Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CA/Santa Clarita
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Santa Clarita, CA

Studies commonly pay $75 to $4,500 per completed study

2,390 clinical trials are currently recruiting participants within 30 miles of Santa Clarita. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

2,390studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Santa Clarita right now

Top 25 of 2,390 recruiting studies, sorted by proximity — each links to its official registry page

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Kaiser Permanente - Panorama City — Panorama City, California (13.6 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
Roy and Patricia Disney Family Cancer Center - Providence Saint Joseph Medical Center ( Site 0135) — Burbank, California (19.5 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Beverly Hills Cancer Center — Beverly Hills, California (24.4 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought
Global Research Management — Glendale, California (23.5 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07553429)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
California Eye Specialists Medical group Inc. — Pasadena, California (27.4 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Children's Hospital Los Angeles — Los Angeles, California (29.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Study to Investigate the Safety and Efficacy of MEDI0618 Compared to Placebo in Adult Participants With Episodic Migraine

Migraine Phase 2 Interventional 488 participants sought
Clinical Research Institute, LCC — Los Angeles, California (29.1 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06602479)

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

Urothelial Cancer, Bladder Cancer Phase 2, Phase 3 Interventional 630 participants sought
Research Site — Glendale, California (23.5 mi) · Sponsor: Daiichi Sankyo
See eligibility & contact on ClinicalTrials.gov (NCT07129993)

Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants

Movement Disorders, Neurorehabilitation N/A Interventional 50 participants sought
UCLA Neural Engineering and Computation Lab — Los Angeles, California (29.1 mi) · Sponsor: University of California, Los Angeles
See eligibility & contact on ClinicalTrials.gov (NCT07236892)

A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1

Narcolepsy Type 1 Phase 3 Interventional 150 participants sought
Alkermes Investigational Site — Los Angeles, California (29.1 mi) · Sponsor: Alkermes, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07455383)

PEACE Trial: Postpartum Evaluation of Antihypertensive Cessation and Efficacy

Postpartum Hypertension (PPHT) Phase 4 Interventional 110 participants sought
UCLA Ronald Reagan — Los Angeles, California (29.1 mi) · Sponsor: University of California, Los Angeles
See eligibility & contact on ClinicalTrials.gov (NCT06915792)

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Solid Tumor, Non-Small-Cell Lung Cancer Phase 1 Interventional 364 participants sought
UCLA Santa Monica Hematology Oncology — Santa Monica, California (27.5 mi) · Sponsor: Astellas Pharma Inc
See eligibility & contact on ClinicalTrials.gov (NCT07094204)

Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis

Children With Medical Complexity (CMC), Multiple Chronic Conditions N/A Interventional 110 participants sought
Children's Hospital Los Angeles — Los Angeles, California (29.1 mi) · Sponsor: University of Utah
See eligibility & contact on ClinicalTrials.gov (NCT07167927)

Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation

Severe Tricuspid Regurgitation N/A Interventional 1,186 participants sought
Los Robles Hospital & Medical Center — Thousand Oaks, California (25.9 mi) · Sponsor: Medtronic Cardiovascular
See eligibility & contact on ClinicalTrials.gov (NCT07321899)

A Study to Investigate Canvuparatide Compared With Placebo in Adult Patients With Hypoparathyroidism

Hypoparathyroidism Phase 3 Interventional 160 participants sought
MBX Biosciences Investigational Site — Los Angeles, California (29.1 mi) · Sponsor: MBX Biosciences
See eligibility & contact on ClinicalTrials.gov (NCT07699471)

Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients

Amyotrophic Lateral Sclerosis Phase 3 Interventional 495 participants sought
University of Southern California — Los Angeles, California (29.1 mi) · Sponsor: AB Science
See eligibility & contact on ClinicalTrials.gov (NCT03127267)

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Solid Tumor, Adult, Metastatic Breast Cancer Phase 1 Interventional 392 participants sought
University of California Los Angeles — Los Angeles, California (29.1 mi) · Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
See eligibility & contact on ClinicalTrials.gov (NCT06625775)

First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours

Hepatocellular Carcinoma Phase 1, Phase 2 Interventional 304 participants sought
Research Site — Los Angeles, California (29.1 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06795022)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Sylmar, California (8.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)
Actively enrolling

Studies you may be able to join near Santa Clarita

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Santa Clarita

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Clearview Medical Research

27141 Hidaway Ave #103, Canyon Country, CA 91351
(323) 633-4730

Flourish Research - Los Angeles (Northridge)

★ 4.9
18433 Roscoe Blvd #208, Northridge, CA 91325
(818) 280-4220
"This clinic is the best and stuff are great and caring if you need to get studied go here in Northridge ."
— John Cariaga (Jon jon), 5★

Clinical Research of California

★ 4.3
7301 Medical Center Dr Unit 405, West Hills, CA 91307

Alliance Research Institute(Roscoe Blvd)

★ 3.9
22110 Roscoe Blvd Suite 202, Canoga Park, CA 91304
(818) 835-9085
"This organization is deceptive, ill trained and will waste your time without any compensation. I have done other trails, and always had a good expe…"
— Michael Nuttall, 1★

Valiance Clinical Research Northridge

★ 5.0
19355 Business Ctr Dr Ste. 2, Northridge, CA 91324
(747) 799-0050
"Went there for a Research project. Ask first about parking. Staff is very helpful and kind, especially Natalie and Justin."
— KAILEH PISTOL (UrbaneGypsy), 5★

Clinical Research Center Centro De Estudios Clinicos

Los Angeles, CA 91345

Alliance Clinical Canoga Park

★ 3.5
22030 Sherman Way #101, Canoga Park, CA 91303
(818) 999-4673
"I was called for a longterm study on migraines. My appointment was 2:30 pm. They were quite rude. She had a tizzy fit that I had a slice of toast and…"
— Paulette carr, 1★

Asclepes Research

★ 3.8
14860 Roscoe Blvd #304, Panorama City, CA 91402
(844) 283-3649
"Where we’re going to my moms appointment and the worker that was at the lobby where we had to wait so my mom can get inside and the worker was yellin…"
— Uriel Recendez, 1★

Northridge Clinical Trials

★ 4.8 (17 reviews)
18433 Roscoe Blvd Ste 101, Northridge, CA 91325
(818) 350-7482
"Loved it here, Luke was so friendly and I love having to talk to them and come here!"
— kenneth lee, 5★

Clinical trials in Santa Clarita: what's recruiting

The Santa Clarita area currently has 2,390 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Santa Clarita, the most active research areas are:

  • Cancer & Oncology10 studies
  • Heart & Vascular2 studies
  • Brain & Mental Health1 studies
  • Diabetes & Metabolism1 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from Santa Clarita, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Santa Clarita

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Santa Clarita participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Santa Clarita pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Santa Clarita safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Santa Clarita, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Santa Clarita?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Santa Clarita?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Santa Clarita.

Paid clinical trials near Santa Clarita

Other metros within reach

Los Angeles, CA2,949 Glendale, CA2,959 Lancaster, CA107 Palmdale, CA131 Thousand Oaks, CA684 Torrance, CA3,253 Long Beach, CA3,361 Oxnard, CA133

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Santa Clarita Bladder Issues Due To Spinal Cord Injury in Santa Clarita All conditions

More of CA

Long Beach3,361 Torrance3,253 Fullerton3,246 Anaheim3,181 Garden Grove3,176 Pomona3,138 Glendale2,959 Los Angeles2,949 Huntington Beach2,863 Hayward2,268 Oakland2,257

New paid studies open every week

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