Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TX/Houston
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Houston, TX

Studies commonly pay $75 to $4,500 per completed study

3,067 clinical trials are currently recruiting participants within 30 miles of Houston. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

3,067studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Houston right now

Top 25 of 3,067 recruiting studies, sorted by proximity — each links to its official registry page

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11, Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11 Phase 2 Interventional 270 participants sought
M D Anderson Cancer Center — Houston, Texas (2.2 mi) · Sponsor: M.D. Anderson Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT00801489)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center — Houston, Texas (2.2 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

HER2-positive Metastatic Breast Cancer N/A Observational 200 participants sought
Ben Taub General Hospital — Houston, Texas (2.2 mi) · Sponsor: Abramson Cancer Center at Penn Medicine
See eligibility & contact on ClinicalTrials.gov (NCT06551116)

Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease

Hematopoietic and Lymphoid Cell Neoplasm, Steroid Refractory Graft Versus Host Disease EARLY/Phase 1 Interventional 24 participants sought
M D Anderson Cancer Center — Houston, Texas (2.2 mi) · Sponsor: M.D. Anderson Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT04744116)

A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF SHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS

Advanced Solid Tumors Phase 1, Phase 2 Interventional 83 participants sought
The University of Texas MD Anderson Cancer Center — Houston, Texas (2.2 mi) · Sponsor: Jiangsu HengRui Medicine Co., Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT05277168)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Houston, Texas (2.2 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

IDH1 wt Allele, Recurrent Anaplastic Astrocytoma Phase 1 Interventional 36 participants sought
M D Anderson Cancer Center — Houston, Texas (2.2 mi) · Sponsor: M.D. Anderson Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT03896568)

Adapting and Assessing the Feasibility of a Telehealth Diabetes Prevention Program for Hispanic Adolescents

Obesity and Type 2 Diabetes N/A Interventional 40 participants sought
USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine — Houston, Texas (2.2 mi) · Sponsor: Baylor College of Medicine
See eligibility & contact on ClinicalTrials.gov (NCT06943001)

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

Metastatic Solid Tumors Phase 1 Interventional 600 participants sought
The University of Texas MD Anderson Cancer Center — Houston, Texas (2.2 mi) · Sponsor: Erasca, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06983743)

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes N/A Observational 200 participants sought
Baylor College of Medicine — Houston, Texas (2.2 mi) · Sponsor: Jaeb Center for Health Research
See eligibility & contact on ClinicalTrials.gov (NCT06837181)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Houston Methodist Hospital Cancer Center — Houston, Texas (2.2 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

Phase 2 Study to Evaluate EI-001 in Non-segmental Vitiligo Patients

Non-segmental Vitiligo Phase 2 Interventional 45 participants sought
Center for Clinical Studies — Houston, Texas (2.2 mi) · Sponsor: Elixiron Immunotherapeutics (Hong Kong) Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT07223229)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center — Houston, Texas (2.2 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Carcinoma, Non-Small-Cell Lung Phase 1, Phase 2 Interventional 450 participants sought
The University of Texas MD Anderson Cancer Center ( Site 0009) — Houston, Texas (2.2 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT04165070)

Natural History of Medullary Thyroid Cancer to Inform Advanced Disease Management

Advanced Thyroid Gland Medullary Carcinoma, Stage III Thyroid Gland Medullary Carcinoma AJCC v8 N/A Observational 2,030 participants sought
M D Anderson Cancer Center — Houston, Texas (2.2 mi) · Sponsor: M.D. Anderson Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT04216732)

Optimizing Beta Blocker Dosage in Women While Using the Wearable Cardioverter Defibrillator

Cardiomyopathies, Heart Failure N/A Interventional 300 participants sought
Texas Cardiology Associates of Houston — Kingwood, Texas (22.4 mi) · Sponsor: Zoll Medical Corporation
See eligibility & contact on ClinicalTrials.gov (NCT04504188)

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

Sleep, Fatigue Phase 2, Phase 3 Interventional 188 participants sought
MD Anderson Cancer Center — Houston, Texas (2.2 mi) · Sponsor: M.D. Anderson Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT05474846)

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Ulcerative Colitis Phase 4 Interventional 65 participants sought
The University of Texas Health Science Center at Houston — Houston, Texas (2.2 mi) · Sponsor: Takeda
See eligibility & contact on ClinicalTrials.gov (NCT06095128)

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis Phase 2 Interventional 168 participants sought
DaVita Clinical Research — Houston, Texas (2.2 mi) · Sponsor: R1 Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06712654)

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Percutaneous Coronary Intervention, Peripheral Endovascular Intervention Phase 4 Interventional 6,000 participants sought
Texas Cardiology Associates of Houston — Kingwood, Texas (22.4 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT06909565)
Actively enrolling

Studies you may be able to join near Houston

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Houston

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

HD Research

★ 3.8
1917 Ashland St, Houston, TX 77008
(281) 369-5765
"Horribly rude lady called to ask questions and just be mean and judgey about ny answers. 0/10 this is a scam."
— Frank Leger, 1★

Helios Clinical Research - Houston

1919 N Loop W Fwy #250, Houston, TX 77008
(214) 550-3029

Spring Clinical Research

★ 4.4
2000 Crawford St Ste 1125, Houston, TX 77002
(281) 888-5564

Clinical Trials - CliniCore Research

★ 5.0
4200 Twelve Oaks Pl, Houston, TX 77027
(713) 589-6400

Center for Clinical Studies

★ 5.0
1401 Binz St Unit 200, Houston, TX 77004
(281) 343-3300

DM Clinical Research - Bellaire (Formerly TCDD)

★ 4.9
6550 Mapleridge St #201, Houston, TX 77081
(346) 550-9559
"Great facility for clinical trials and safe way to make money while helping our community."
— Dav “Shag Dog” Boer, 5★

West Houston Clinical Research Service LLC

★ 4.3
2026 Wirt Rd, Houston, TX 77055
(281) 738-2642

Prolato Clinical Research Center

★ 4.7
8990 Kirby Dr Ste 208, Houston, TX 77054
(832) 338-9118
"I feel really grateful for this place, staff were very kind and informative. If you’re looking for a place for clinical research for you or a family …"
— Doirisdel Marcano, 5★

Houston Clinical Trials by Power

3139 W Holcombe Blvd A183, Houston, TX 77025

Clinical trials in Houston: what's recruiting

The Houston area currently has 3,067 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Houston, the most active research areas are:

  • Cancer & Oncology14 studies
  • Heart & Vascular3 studies
  • Diabetes & Metabolism2 studies
  • Brain & Mental Health1 studies
  • Immune & Skin1 studies

Every listing shows the study phase, the recruiting site and its distance from Houston, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Houston

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Houston participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Houston pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Houston safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Houston?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Houston.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Houston typically complete one or two studies per year.

Paid clinical trials near Houston

Other metros within reach

Pasadena, TX3,004 Galveston, TX203 College Station, TX46 Beaumont, TX43 Lake Charles, LA30 Austin, TX723 Waco, TX52 Killeen, TX102

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Houston Chronic Kidney Disease (HealthMatch) in Houston Bladder Issues Due To Spinal Cord Injury in Houston All conditions

More of TX

Pasadena3,004 Irving1,967 Grand Prairie1,935 Dallas1,857 Arlington1,856 Garland1,818 Plano1,809 Frisco1,808 Mesquite1,759 San Antonio1,026 Austin723

New paid studies open every week

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