Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TX/Plano
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Plano, TX

Studies commonly pay $75 to $4,500 per completed study

1,809 clinical trials are currently recruiting participants within 30 miles of Plano. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,809studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Plano right now

Top 25 of 1,809 recruiting studies, sorted by proximity — each links to its official registry page

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Medical City Dallas Hospital — Dallas, Texas (18.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)

Locally Advanced Solid Tumor, Metastatic Solid Tumor Phase 1 Interventional 30 participants sought
Texas Oncology — Dallas, Texas (18.8 mi) · Sponsor: Acepodia Biotech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06415487)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Texas Oncology DFW — Dallas, Texas (18.8 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

Niemann-Pick Type C Disease, GM1 Gangliosidosis Phase 3 Interventional 147 participants sought
Children's Medical Center Dallas — Dallas, Texas (18.8 mi) · Sponsor: Azafaros B.V.
See eligibility & contact on ClinicalTrials.gov (NCT07054515)

Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity

Physical Inactivity, Phosphate Overload N/A Interventional 124 participants sought
University of Texas Southwestern — Dallas, Texas (18.8 mi) · Sponsor: University of Texas Southwestern Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT05147909)

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
Tekton Research — McKinney, Texas (12.8 mi) · Sponsor: Medtronic MiniMed, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07228117)

Registry Study to Evaluate the Clinical Outcome of Cancer Patients and Benign Diseases Treated With Radiation

Cancer N/A Observational 10,000 participants sought
UT Southwestern Medical Centre — Dallas, Texas (18.8 mi) · Sponsor: University of Texas Southwestern Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT03617237)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
Parkland Health and Hospital System — Dallas, Texas (18.8 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

Obesity Phase 3 Interventional 600 participants sought
North Texas Endocrine Center — Dallas, Texas (18.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07503210)

APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women

Overactive Bladder (OAB), Urinary Urgency N/A Interventional 596 participants sought
UT Southwestern Medical Center — Dallas, Texas (18.8 mi) · Sponsor: Medstar Health Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT06797245)

Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS

COPD, Smoking N/A Interventional 290 participants sought
Metroplex Pulmonary & Sleep Center — McKinney, Texas (12.8 mi) · Sponsor: Philip Morris Products S.A.
See eligibility & contact on ClinicalTrials.gov (NCT07108166)

A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies

Solid Tumors Phase 2 Interventional 170 participants sought
Texas Oncology - Baylor Charles A. Sammons Cancer Center — Dallas, Texas (18.8 mi) · Sponsor: Mirati Therapeutics Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07415031)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
UT Southwestern Clinical Center at Richardson/Plano — Richardson, Texas (7.1 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Optimizing Beta Blocker Dosage in Women While Using the Wearable Cardioverter Defibrillator

Cardiomyopathies, Heart Failure N/A Interventional 300 participants sought
CardioVoyage — McKinney, Texas (12.8 mi) · Sponsor: Zoll Medical Corporation
See eligibility & contact on ClinicalTrials.gov (NCT04504188)

Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite Polypharmacy

Primary Open Angle Glaucoma, Open Angle Glaucoma N/A Interventional 129 participants sought
Glaucoma Associates of Texas — Dallas, Texas (18.8 mi) · Sponsor: Sanoculis Ltd
See eligibility & contact on ClinicalTrials.gov (NCT06313749)

A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis

Colitis Ulcerative Phase 2 Interventional 204 participants sought
Texas Digestive Disease Consultants - Southlake- Site Number : 8400015 — Southlake, Texas (23.6 mi) · Sponsor: Sanofi
See eligibility & contact on ClinicalTrials.gov (NCT06867094)

A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors

MTAP-deleted Solid Tumors Phase 1, Phase 2 Interventional 450 participants sought
NEXT Dallas - Oncology Department — Irving, Texas (20.0 mi) · Sponsor: Bayer
See eligibility & contact on ClinicalTrials.gov (NCT06914128)
Actively enrolling

Studies you may be able to join near Plano

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Plano

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

ClinRx Research

★ 4.5
6300 Stonewood Dr Ste 102, Plano, TX 75024
(972) 886-8969
"The staff is very professional and friendly. The procedure was very good, and I didn't experience any complications. I recommend ClinRx for any futur…"
— Johnny Thompson, 5★

North Texas Center for Clinical Research

★ 5.0
3880 Parkwood Blvd, Frisco, TX 75034
(214) 618-0220
"Aly, Summer and Keisha are awesome. Very little waiting time and the staff are always there to welcome you with a smile."
— Brett Kozlowski, 5★

ACRC Trials

★ 4.8
5655 W Spring Creek Pkwy Ste 125, Plano, TX 75024
(469) 382-3949
"Was in a study with ACRC and it was great! Thorough explanations for the study, and super friendly coordinator who called periodically to see how th…"
— Kara B, 5★

Future Med Clinical Research

5072 W Plano Pkwy #190, Plano, TX 75093
(972) 312-7285

Clinical Investigations of Texas

★ 5.0
1524 Independence Pkwy M, Plano, TX 75075
(972) 599-1530
"Clinical Investigations is extremely professional and makes patient care a priority. Clinical trials lead to new treatments for those in need!"
— Pam Vincent, 5★

Pillar Clinical Research, Richardson, Texas

★ 4.8
630 N Coit Rd Ste.2200, Richardson, TX 75080
(214) 396-4844
"Berry beautiful place valm the Staff are very admint about about take care of you it was a beautiful experience I love you all. I would definitely re…"
— Vig Dall, 5★

Discovery Clinical Trials - Dallas

★ 4.9
7777 Forest Ln Bldg D, Suite 1200, Dallas, TX 75230
(855) 468-7788
"The office staff are so professional and caring just like family well educated and explained the procedures love being a part of this trial❤️❤️❤️"
— delia anthony, 5★

Callier Clinical Research Center

811 Synergy Park Blvd, Richardson, TX 75080

SGS USA - Richardson

★ 4.4
1801 N Glenville Dr, Richardson, TX 75081
(833) 530-7596
"Their email doesn't work.<br>They hardly answer phone calls.<br>Zelle payment didn't work and I updated my info and spent 5 hours trying to get a hol…"
— Ruth Curiel, 1★

Clinical trials in Plano: what's recruiting

The Plano area currently has 1,809 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Plano, the most active research areas are:

  • Cancer & Oncology12 studies
  • Diabetes & Metabolism3 studies
  • Liver & Kidney1 studies
  • Lungs & Breathing1 studies
  • Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from Plano, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Plano

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Plano participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Plano?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Plano, TX?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Plano?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Plano typically complete one or two studies per year.

Paid clinical trials near Plano

Other metros within reach

Frisco, TX1,808 McKinney, TX446 Garland, TX1,818 Dallas, TX1,857 Irving, TX1,967 Mesquite, TX1,759 Denton, TX371 Grand Prairie, TX1,935

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Plano Chronic Kidney Disease (HealthMatch) in Plano Bladder Issues Due To Spinal Cord Injury in Plano All conditions

More of TX

Houston3,067 Pasadena3,004 Irving1,967 Grand Prairie1,935 Dallas1,857 Arlington1,856 Garland1,818 Frisco1,808 Mesquite1,759 San Antonio1,026 Austin723

New paid studies open every week

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