Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TX/Denton
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Denton, TX

Studies commonly pay $75 to $4,500 per completed study

371 clinical trials are currently recruiting participants within 30 miles of Denton. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

371studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Denton right now

Top 25 of 371 recruiting studies, sorted by proximity — each links to its official registry page

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Ulcerative Colitis Phase 4 Interventional 65 participants sought
Texas Digestive Disease Consultants (TDDC), Southlake — Southlake, Texas (19.1 mi) · Sponsor: Takeda
See eligibility & contact on ClinicalTrials.gov (NCT06095128)

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
Revival Research Institute — Denton, Texas (0.5 mi) · Sponsor: Medtronic MiniMed, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07228117)

Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis

Rheumatoid Arthritis N/A Interventional 40 participants sought
Precision Comprehensive Clinical Research Solutions — Colleyville, Texas (23.3 mi) · Sponsor: Surf Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT07293871)

A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies

Solid Tumors Phase 2 Interventional 170 participants sought
Texas Oncology - DFW — Grapevine, Texas (19.9 mi) · Sponsor: Mirati Therapeutics Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07415031)

A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System

Atrial Fibrillation N/A Interventional 276 participants sought
Baylor Scott & White Research Institute at The Heart Hospital Baylor Plano — Plano, Texas (29.0 mi) · Sponsor: Biosense Webster, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07227532)

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

Asthma Phase 3 Interventional 440 participants sought
Research Site — Frisco, Texas (19.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06307665)

Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients

Irritability Associated With Autism Spectrum Disorder Phase 3 Interventional 160 participants sought
North Pointe Psychiatry — Flower Mound, Texas (14.3 mi) · Sponsor: Intra-Cellular Therapies, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06690398)

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease

Sjögren, Sjogren Disease Phase 1 Interventional 36 participants sought
Cullinan Investigative Site — Plano, Texas (29.0 mi) · Sponsor: Cullinan Therapeutics Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07041099)

Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device Exemption] Study)

Carotid Artery Calcification, Carotid Artery Diseases N/A Interventional 185 participants sought
Baylor Scott & White Plano — Plano, Texas (29.0 mi) · Sponsor: Shockwave Medical, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07062471)

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

Myotonic Dystrophy Type 1 (DM1) Phase 1, Phase 2 Interventional 116 participants sought
Neurology Rare Disease Center — Denton, Texas (0.5 mi) · Sponsor: Dyne Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT05481879)

A Study of SGT-003 Gene Therapy in Ambulant Males With Duchenne Muscular Dystrophy (IMPACT DUCHENNE)

Duchenne Muscular Dystrophy Phase 3 Interventional 80 participants sought
Neurology Rare Disease Center — Flower Mound, Texas (14.3 mi) · Sponsor: Solid Biosciences Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07160634)

Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets

Type 2 Diabetes Phase 2 Interventional 60 participants sought
Epic Clinical Research — Lewisville, Texas (14.6 mi) · Sponsor: Biomea Fusion Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07502495)

Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease

Primary Mitochondrial Disease Phase 2 Interventional 180 participants sought
Neurology and Neuromuscular Care Center-Neurology Rare Disease Center — Flower Mound, Texas (14.3 mi) · Sponsor: Pharming Technologies B.V.
See eligibility & contact on ClinicalTrials.gov (NCT05650229)

Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration

Age-Related Macular Degeneration, Geographic Atrophy Phase 1, Phase 2 Interventional 60 participants sought
Retina Center of Texas — Southlake, Texas (19.1 mi) · Sponsor: Perceive Biotherapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06087458)

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Cardiovascular Risk, Acute Myocardial Infarction (AMI) Phase 3 Interventional 10,000 participants sought
Baylor Scott & White Res Inst — Plano, Texas (29.0 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT06118281)

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

Polymyositis, Dermatomyositis Phase 3 Interventional 240 participants sought
Research Site — Colleyville, Texas (23.3 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06455449)

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

Metastatic Colorectal Cancer Phase 1 Interventional 542 participants sought
Texas Oncology - Northeast Texas — Denton, Texas (0.5 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT04929223)

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

Macular Degeneration, Age-Related Macular Degeneration Phase 2, Phase 3 Interventional 960 participants sought
Retina Center of Texas — Southlake, Texas (19.1 mi) · Sponsor: EyeBiotech Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT07440225)

A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

Asthma Phase 3 Interventional 231 participants sought
Research Site — Frisco, Texas (19.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06023589)
Actively enrolling

Studies you may be able to join near Denton

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Denton

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Epic Medical Research - Denton

2625 Scripture St #102, Denton, TX 76201
(972) 777-6956

Clinical Research Center-N Texas

2921 Country Club Rd #101, Denton, TX 76210
(940) 484-5010

Center for Psychosocial Health Disparities Research

Terrill Hall, 1611 W Mulberry St, Denton, TX 76201
(940) 565-2000

Elevate Clinical Research - Neurology Rare Disease Center

2817 S Mayhill Rd #115, Denton, TX 76208
(832) 240-9765

North Texas Center for Clinical Research

★ 5.0
3880 Parkwood Blvd, Frisco, TX 75034
(214) 618-0220
"Aly, Summer and Keisha are awesome. Very little waiting time and the staff are always there to welcome you with a smile."
— Brett Kozlowski, 5★

DelRicht Research of Dallas Clinical Trials

★ 4.9
1050 S Coit Rd Ste 10, Prosper, TX 75078
(972) 807-5787
"Working with both Adriana and Kelsey was a great experience. The care I received as well as education was terrific!"
— Dan Chase, 5★

Pillar Clinical Research, Richardson, Texas

★ 4.8
630 N Coit Rd Ste.2200, Richardson, TX 75080
(214) 396-4844
"Berry beautiful place valm the Staff are very admint about about take care of you it was a beautiful experience I love you all. I would definitely re…"
— Vig Dall, 5★

DM Clinical Research- Irving

★ 4.3
Medical Office Building II, 2021 N MacArthur Blvd Ste 450, Irving, TX 75061
(945) 298-0007
"Great Clinical Place to pretesapate! Love the Team very nice caring people there."
— Janie Torres, 5★

Discovery Clinical Trials - Dallas

★ 4.9
7777 Forest Ln Bldg D, Suite 1200, Dallas, TX 75230
(855) 468-7788
"The office staff are so professional and caring just like family well educated and explained the procedures love being a part of this trial❤️❤️❤️"
— delia anthony, 5★

Clinical trials in Denton: what's recruiting

The Denton area currently has 371 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Denton, the most active research areas are:

  • Immune & Skin5 studies
  • Heart & Vascular4 studies
  • Diabetes & Metabolism2 studies
  • Cancer & Oncology2 studies
  • Lungs & Breathing2 studies

Every listing shows the study phase, the recruiting site and its distance from Denton, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Denton

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Denton participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Denton pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Denton safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Denton, TX?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Denton?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Denton?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Denton.

Paid clinical trials near Denton

Other metros within reach

Frisco, TX1,808 Irving, TX1,967 Plano, TX1,809 McKinney, TX446 Fort Worth, TX606 Arlington, TX1,856 Grand Prairie, TX1,935 Dallas, TX1,857

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Denton Bladder Issues Due To Spinal Cord Injury in Denton All conditions

More of TX

Houston3,067 Pasadena3,004 Irving1,967 Grand Prairie1,935 Dallas1,857 Arlington1,856 Garland1,818 Plano1,809 Frisco1,808 Mesquite1,759 San Antonio1,026 Austin723

New paid studies open every week

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