Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TX/Denton
Updated October 2026 from ClinicalTrials.gov

Paid Clinical Trials in Denton, TX

Studies commonly pay $75 to $4,500 per completed study

380 clinical trials are currently recruiting participants within 30 miles of Denton. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

380studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Denton right now

Top 25 of 380 recruiting studies, sorted by proximity — each links to its official registry page

Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies

Neuromyelitis Optica Spectrum Disorder, NMOSD N/A Observational 200 participants sought
Clinical Trial Site — Plano, Texas (29.0 mi) · Sponsor: Alexion Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05966467)

Intracardiac Versus Transesophageal Echocardiographic Guidance for Left Atrial Appendage Occlusion

Left Atrial Appendage Closure N/A Interventional 444 participants sought
Baylor Scott and White Heart Hospital — Plano, Texas (29.0 mi) · Sponsor: Baylor Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT06348394)

A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

Diffuse Cutaneous Systemic Sclerosis Phase 2 Interventional 200 participants sought
Arthritis and Rheumatology Ins — Allen, Texas (28.4 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06470048)

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Breast Neoplasms, Triple Negative Breast Neoplasms Phase 3 Interventional 2,400 participants sought
Texas Oncology - Northeast Texas ( Site 8002) — Flower Mound, Texas (14.3 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06966700)

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

Colitis, Ulcerative Phase 3 Interventional 882 participants sought
GI Alliance Southlake — Southlake, Texas (19.1 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07196748)

A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)

Muscular Atrophy, Spinal Phase 3 Interventional 30 participants sought
Neurology Rare Disease Center — Flower Mound, Texas (14.3 mi) · Sponsor: Biogen
See eligibility & contact on ClinicalTrials.gov (NCT07221669)

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

Relapsing Multiple Sclerosis, Multiple Sclerosis N/A Observational 2,000 participants sought
TG Therapeutics Investigational Trial Site — Frisco, Texas (19.0 mi) · Sponsor: TG Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06433752)

Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations

Solid Tumours Phase 2 Interventional 588 participants sought
Texas Oncology - Plano West — Plano, Texas (29.0 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT06581432)

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus Phase 3 Interventional 450 participants sought
Sl0044 50562 — Frisco, Texas (19.0 mi) · Sponsor: UCB Biopharma SRL
See eligibility & contact on ClinicalTrials.gov (NCT06617325)

RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures

Focal Onset Seizures Phase 2 Interventional 216 participants sought
Stryde Research — Frisco, Texas (19.0 mi) · Sponsor: Supernus Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06798896)

A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

Chronic Idiopathic Constipation (CIC) Phase 3 Interventional 692 participants sought
DelRicht Clinical Research - McKinney — Prosper, Texas (19.7 mi) · Sponsor: Ardelyx
See eligibility & contact on ClinicalTrials.gov (NCT07382167)

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

Type 2 Diabetes, Cortisol Excess Phase 2 Interventional 1,500 participants sought
Alliance Clinical - Lewisville (Epic Clinical Research) — Lewisville, Texas (14.6 mi) · Sponsor: Sparrow Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07296484)

A Study to Evaluate the Efficacy, Safety and Tolerability of ALKS 2680 in Adults With Narcolepsy Type 1 (Brilliance NT1 - 304)

Narcolepsy Type 1 Phase 3 Interventional 150 participants sought
Alkermes Investigational Site — Frisco, Texas (19.0 mi) · Sponsor: Alkermes, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07540897)

A Study to Evaluate Efficacy, Safety, and Tolerability of Remibrutinib in Adult Participants With Severe Chronic Pruritus of Unknown Origin (CPUO)

Chronic Pruritus of Unknown Origin Phase 3 Interventional 180 participants sought
Dermatology Solutions — Grapevine, Texas (19.9 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07811869)

A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer

Gastric Adenocarcinoma, Gastric Cancer Phase 2 Interventional 146 participants sought
Texas Oncology Grapevine — Grapevine, Texas (19.9 mi) · Sponsor: Toray Industries, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06038578)

Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease

Arterial Disease of Legs, Below-the-knee Obstruction N/A Interventional 368 participants sought
The Heart Hospital Baylor Plano — Plano, Texas (29.0 mi) · Sponsor: Concept Medical Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06182397)

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

Lower Extremity Acute Limb Ischemia, LE ALI N/A Observational 300 participants sought
Baylor Scott & White The Heart Hospital - Plano — Plano, Texas (29.0 mi) · Sponsor: Penumbra Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06747117)

Continuous Observational Monitoring Program for Allay™ Hydrogel Cap Safety and Success Study

Peripheral Nerve Injuries N/A Observational 1,000 participants sought
Complete Foot and Ankle Care of North Texas, PA — Denton, Texas (0.5 mi) · Sponsor: Tulavi Therapeutics,Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07246980)

A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice

Asthma N/A Observational 2,500 participants sought
Lumi Research - Hurst - Site Number: 840164 — Hurst, Texas (27.3 mi) · Sponsor: Sanofi
See eligibility & contact on ClinicalTrials.gov (NCT07556159)

Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD

Rhinovirus Infection Phase 2 Interventional 180 participants sought
Epic Clinical Research, LLC — Lewisville, Texas (14.6 mi) · Sponsor: Altesa Biosciences, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07610395)

Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD

Attention-Deficit/Hyperactivity Disorder Phase 4 Interventional 286 participants sought
AIM Trials, LLC — Plano, Texas (29.0 mi) · Sponsor: Supernus Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04781140)

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Cardiovascular Diseases, Heart Diseases N/A Interventional 780 participants sought
Baylor Scott & White Medical Center - Plano — Plano, Texas (29.0 mi) · Sponsor: BrioHealth Solutions, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06310031)

Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device Exemption] Study)

Carotid Artery Calcification, Carotid Artery Diseases N/A Interventional 185 participants sought
Baylor Scott & White Plano — Plano, Texas (29.0 mi) · Sponsor: Shockwave Medical, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07062471)
Actively enrolling

Studies you may be able to join near Denton

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Denton

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Epic Medical Research - Denton

2625 Scripture St #102, Denton, TX 76201
(972) 777-6956

Clinical Research Center-N Texas

2921 Country Club Rd #101, Denton, TX 76210
(940) 484-5010

Center for Psychosocial Health Disparities Research

Terrill Hall, 1611 W Mulberry St, Denton, TX 76201
(940) 565-2000

Elevate Clinical Research - Neurology Rare Disease Center

2817 S Mayhill Rd #115, Denton, TX 76208
(832) 240-9765

North Texas Center for Clinical Research

★ 5.0
3880 Parkwood Blvd, Frisco, TX 75034
(214) 618-0220
"Aly, Summer and Keisha are awesome. Very little waiting time and the staff are always there to welcome you with a smile."
— Brett Kozlowski, 5★

DelRicht Research of Dallas Clinical Trials

★ 4.9
1050 S Coit Rd Ste 10, Prosper, TX 75078
(972) 807-5787
"Working with both Adriana and Kelsey was a great experience. The care I received as well as education was terrific!"
— Dan Chase, 5★

Pillar Clinical Research, Richardson, Texas

★ 4.8
630 N Coit Rd Ste.2200, Richardson, TX 75080
(214) 396-4844
"Berry beautiful place valm the Staff are very admint about about take care of you it was a beautiful experience I love you all. I would definitely re…"
— Vig Dall, 5★

DM Clinical Research- Irving

★ 4.3
Medical Office Building II, 2021 N MacArthur Blvd Ste 450, Irving, TX 75061
(945) 298-0007
"Great Clinical Place to pretesapate! Love the Team very nice caring people there."
— Janie Torres, 5★

Discovery Clinical Trials - Dallas

★ 4.9
7777 Forest Ln Bldg D, Suite 1200, Dallas, TX 75230
(855) 468-7788
"The office staff are so professional and caring just like family well educated and explained the procedures love being a part of this trial❤️❤️❤️"
— delia anthony, 5★

Clinical trials in Denton: what's recruiting

The Denton area currently has 380 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Denton, the most active research areas are:

  • Immune & Skin2 studies
  • Cancer & Oncology2 studies
  • Diabetes & Metabolism1 studies
  • Lungs & Breathing1 studies
  • Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from Denton, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Denton

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Denton participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Denton pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Denton safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Denton, TX?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Denton?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Denton?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Denton.

Paid clinical trials near Denton

Other metros within reach

Frisco, TX1,838 Irving, TX2,008 Plano, TX1,839 McKinney, TX454 Fort Worth, TX629 Arlington, TX1,893 Grand Prairie, TX1,978 Dallas, TX1,887

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Denton Bladder Issues Due To Spinal Cord Injury in Denton All conditions

More of TX

Houston3,077 Pasadena3,010 Irving2,008 Grand Prairie1,978 Arlington1,893 Dallas1,887 Garland1,848 Plano1,839 Frisco1,838 Mesquite1,788 San Antonio1,015 Austin751

New paid studies open every week

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