Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TX/San Antonio
Updated October 2026 from ClinicalTrials.gov

Paid Clinical Trials in San Antonio, TX

Studies commonly pay $75 to $4,500 per completed study

1,014 clinical trials are currently recruiting participants within 30 miles of San Antonio. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,014studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near San Antonio right now

Top 25 of 1,014 recruiting studies, sorted by proximity — each links to its official registry page

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

Glioma Phase 1, Phase 2 Interventional 55 participants sought
The Cancer Therapy and Research Center at UTHSCSA — San Antonio, Texas (3.3 mi) · Sponsor: Cerenome
See eligibility & contact on ClinicalTrials.gov (NCT01906385)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Retina Consultants of Texas — Schertz, Texas (16.5 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC) Phase 1 Interventional 604 participants sought
START — San Antonio, Texas (3.3 mi) · Sponsor: Revolution Medicines, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06040541)

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis Phase 2 Interventional 168 participants sought
US Renal Care - South San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: R1 Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06712654)

A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

KRAS G12C Mutation, KRAS G12S Mutation Phase 1 Interventional 140 participants sought
NEXT Oncology — San Antonio, Texas (3.3 mi) · Sponsor: Kumquat Biosciences Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06720987)

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

Triple Negative Breast Cancer, HER2-negative Breast Cancer Phase 1 Interventional 96 participants sought
Dren Investigational Site — San Antonio, Texas (3.3 mi) · Sponsor: Dren Bio
See eligibility & contact on ClinicalTrials.gov (NCT06999187)

A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)

Chronic Inducible Urticaria, Cold Urticaria Phase 3 Interventional 240 participants sought
RFSA Dermatology — San Antonio, Texas (3.3 mi) · Sponsor: Celldex Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT07266402)

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought
Medical Center Ophthalmology Associates — San Antonio, Texas (3.3 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07553429)

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Non-small Cell Lung Cancer, Histiocytic Neoplasm Phase 1, Phase 2 Interventional 554 participants sought
START San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: Institut de Recherches Internationales Servier
See eligibility & contact on ClinicalTrials.gov (NCT05786924)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
Texas Oncology - San Antonio ( Site 8009) — San Antonio, Texas (3.3 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis

Lewy Body Dementia Psychosis Phase 2 Interventional 180 participants sought
The University of Texas Health Science Center San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: ACADIA Pharmaceuticals Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07029581)

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

HNSCC, ESCC Phase 1 Interventional 150 participants sought
Normunity Investigational Site — San Antonio, Texas (3.3 mi) · Sponsor: Normunity AccelCo, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07182149)

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma, Relapsed/Refractory Multiple Myeloma Phase 2 Interventional 100 participants sought
START San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: C4 Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07284758)

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

Colorectal Cancer, Colorectal Cancer (CRC) Phase 1 Interventional 80 participants sought
NEXT Oncology — San Antonio, Texas (3.3 mi) · Sponsor: Cartography Biosciences
See eligibility & contact on ClinicalTrials.gov (NCT07321106)

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

Non-Small Cell Lung Cancer (NSCLC) Phase 3 Interventional 750 participants sought
Texas Oncology - San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT07361510)

A Study to Investigate Canvuparatide Compared With Placebo in Adult Patients With Hypoparathyroidism

Hypoparathyroidism Phase 3 Interventional 160 participants sought
MBX Biosciences Investigational Site — Shavano Park, Texas (8.6 mi) · Sponsor: MBX Biosciences
See eligibility & contact on ClinicalTrials.gov (NCT07699471)

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

Advanced Solid Tumor Phase 1, Phase 2 Interventional 499 participants sought
Clinical Trial Site — San Antonio, Texas (3.3 mi) · Sponsor: Arvinas Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07749586)

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma Phase 1 Interventional 694 participants sought
NEXT Oncology /ID# 243007 — San Antonio, Texas (3.3 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT05005403)

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

Amyloid Plaque, Beta-Amyloid Phase 1, Phase 2 Interventional 304 participants sought
UT Health San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: AC Immune SA
See eligibility & contact on ClinicalTrials.gov (NCT05462106)

A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease

Chronic Kidney Disease Phase 2 Interventional 465 participants sought
Clinical Advancement Center — San Antonio, Texas (3.3 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT06717698)

Behavioral Economic Intervention to Improve HIV Behaviors in Sexual Minority Individuals

HIV Prevention N/A Interventional 60 participants sought
University of Texas Health Science Center at San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: The University of Texas Health Science Center at San Antonio
See eligibility & contact on ClinicalTrials.gov (NCT06745947)

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

Limited Stage Small Cell Lung Cancer Phase 2 Interventional 250 participants sought
Texas Oncology - San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: SCRI Development Innovations, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06773910)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — San Antonio, Texas (3.3 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)
Actively enrolling

Studies you may be able to join near San Antonio

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in San Antonio

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Flourish Research - San Antonio

★ 4.3
5430 Fredericksburg Rd #200, San Antonio, TX 78229
(210) 714-0067
"The staff is over worked but always pleasant and working hard to get you out fast."
— YVONNE B, 5★

Sun Research Institute

★ 4.8
427 9th St, San Antonio, TX 78215
(210) 227-1289
"I absolutely ADORE the staff at SRI!!<br><br>Nina is the face of SRI. She greets you and asks if there is anything with which she can help. She also …"
— C Boyd, 5★

DM Clinical Research — San Antonio

★ 4.7
315 N San Saba Suite 102, San Antonio, TX 78207
(830) 283-7997
"I will be there. On the 9th. Thank u for ur reminder"
— Paul, 4★

Wellness Clinical Research Center

2714 West Ave, San Antonio, TX 78201

Southern Star Research Institute

★ 5.0
2833 Babcock Rd #206, San Antonio, TX 78229
(210) 581-2812
"They have been really great. Everything is tired so studies. It has helped my tummy been like I think 5 plus years"
— Virginia Zamora Davila, 5★

​Quality Research Inc

★ 4.9
303 W Sunset Rd Ste 102, San Antonio, TX 78209
(210) 864-8844
"Kaye is very knowledgeable, she explained everything about the result of our fibroscan. She took her time to answer all our questions and gave us re…"
— Rose Alonzo, 5★

Pinnacle Clinical Research

★ 4.7
5109 Medical Dr Ste 200, San Antonio, TX 78229
(210) 982-0320

Chromosome 18 Clinical Research Center

★ 4.8
7703 Floyd Curl Drive, Medical School Building, 5th Floor, Suite 533F, San Antonio, TX 78229
(210) 567-5321
"Great organization! They are doing wonderful work for the Chromosome 18 community, please support them in any way you can. Our family attended the an…"
— Jonathon Larson, 5★

Discovery Clinical Trials Corporate

★ 5.0
4242 Medical Dr Bldg 5, San Antonio, TX 78229
(855) 468-7788
"The staff at Discovery Clinical Trials are very professional and treat people with dignity and respect. They are thorough in explaining participation…"
— David X Casillas, 5★

Clinical trials in San Antonio: what's recruiting

The San Antonio area currently has 1,014 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to San Antonio, the most active research areas are:

  • Cancer & Oncology17 studies
  • Liver & Kidney2 studies
  • Heart & Vascular1 studies
  • Diabetes & Metabolism1 studies
  • Lungs & Breathing1 studies

Every listing shows the study phase, the recruiting site and its distance from San Antonio, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in San Antonio

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

San Antonio participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in San Antonio safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in San Antonio, TX?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in San Antonio?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in San Antonio typically complete one or two studies per year.

Paid clinical trials near San Antonio

Other metros within reach

Austin, TX741 Killeen, TX106 Corpus Christi, TX67 Laredo, TX22 Waco, TX53 College Station, TX46 Houston, TX3,069 McAllen, TX137

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in San Antonio Chronic Kidney Disease (HealthMatch) in San Antonio Bladder Issues Due To Spinal Cord Injury in San Antonio All conditions

More of TX

Houston3,069 Pasadena3,009 Irving1,994 Grand Prairie1,962 Dallas1,877 Arlington1,876 Garland1,836 Plano1,829 Frisco1,828 Mesquite1,776 Austin741

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