Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TX/San Antonio
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in San Antonio, TX

Studies commonly pay $75 to $4,500 per completed study

1,026 clinical trials are currently recruiting participants within 30 miles of San Antonio. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,026studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near San Antonio right now

Top 25 of 1,026 recruiting studies, sorted by proximity — each links to its official registry page

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Retina Consultants of Texas — Schertz, Texas (16.5 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Children's Hospital of San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis Phase 2 Interventional 168 participants sought
US Renal Care - South San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: R1 Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06712654)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
University of Texas Health Science Center at San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05561387)

Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis

Lewy Body Dementia Psychosis Phase 2 Interventional 180 participants sought
The University of Texas Health Science Center San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: ACADIA Pharmaceuticals Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07029581)

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

Asthma Phase 3 Interventional 440 participants sought
Research Site — San Antonio, Texas (3.3 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06307665)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — San Antonio, Texas (3.3 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 710 participants sought
Texas Oncology San Antonio Medical Center — San Antonio, Texas (3.3 mi) · Sponsor: Daiichi Sankyo
See eligibility & contact on ClinicalTrials.gov (NCT07022483)

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

Solid Tumor Cancer, Locally Advanced Phase 1, Phase 2 Interventional 480 participants sought
Avenzo Therapeutics Recruiting Site — San Antonio, Texas (3.3 mi) · Sponsor: Avenzo Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07038343)

A Study to Evaluate Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects

Iron Deficiency Anemia Phase 3 Interventional 75 participants sought
Sun Research Institute — San Antonio, Texas (3.3 mi) · Sponsor: AMAG Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT03893045)

Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

Sleep Wake Disorders, Sleep Disorders, Circadian Rhythm Phase 3 Interventional 70 participants sought
Vanda Investigational Site — San Antonio, Texas (3.3 mi) · Sponsor: Vanda Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT04652882)

Evaluating Treatments for Suicidal Veterans With PTSD

Self-directed Violence, Post-traumatic Stress Disorder (PTSD) N/A Interventional 125 participants sought
South Texas Health Care System, San Antonio, TX — San Antonio, Texas (3.3 mi) · Sponsor: VA Office of Research and Development
See eligibility & contact on ClinicalTrials.gov (NCT05974631)

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes N/A Observational 200 participants sought
The University of Texas Health Science Center at San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: Jaeb Center for Health Research
See eligibility & contact on ClinicalTrials.gov (NCT06837181)

Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes

Peripheral Arterial Disease N/A Observational 14,000 participants sought
UT Health Sciences Center — San Antonio, Texas (3.3 mi) · Sponsor: Baylor Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT01904851)

Comparing Antipsychotic Medications in LBD Over Time

Parkinson's Disease Psychosis, Dementia With Lewy Bodies Phase 4 Interventional 94 participants sought
University Health System — San Antonio, Texas (3.3 mi) · Sponsor: The University of Texas Health Science Center at San Antonio
See eligibility & contact on ClinicalTrials.gov (NCT05590637)

Rotator Cuff Repairs With or Without BioEnthesis™ Augmentation

Rotator Cuff Tears, Rotator Cuff Injuries Phase 4 Interventional 100 participants sought
Brooke Army Medical Center — San Antonio, Texas (3.3 mi) · Sponsor: Brooke Army Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT06289686)

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

Bladder Carcinoma, Ureter Carcinoma N/A Observational 2,020 participants sought
The University of Texas Health Science Center at San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: Guardant Health, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05059444)

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Phase 3 Interventional 1,200 participants sought
Texas Oncology - San Antonio ( Site 8006) — San Antonio, Texas (3.3 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06136559)

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

Cancer, Tumor, Solid Phase 1, Phase 2 Interventional 168 participants sought
NEXT Oncology — San Antonio, Texas (3.3 mi) · Sponsor: OncoResponse, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06090266)

Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment

Parenteral Nutrition Associated Liver Disease (PNALD), Essential Fatty Acid Deficiency N/A Observational 40 participants sought
The University of Texas Health Science Center at San Antonio — San Antonio, Texas (3.3 mi) · Sponsor: Fresenius Kabi
See eligibility & contact on ClinicalTrials.gov (NCT06274788)
Actively enrolling

Studies you may be able to join near San Antonio

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in San Antonio

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Flourish Research - San Antonio

★ 4.3
5430 Fredericksburg Rd #200, San Antonio, TX 78229
(210) 714-0067
"The staff is over worked but always pleasant and working hard to get you out fast."
— YVONNE B, 5★

Sun Research Institute

★ 4.8
427 9th St, San Antonio, TX 78215
(210) 227-1289
"I absolutely ADORE the staff at SRI!!<br><br>Nina is the face of SRI. She greets you and asks if there is anything with which she can help. She also …"
— C Boyd, 5★

DM Clinical Research — San Antonio

★ 4.7
315 N San Saba Suite 102, San Antonio, TX 78207
(830) 283-7997
"I will be there. On the 9th. Thank u for ur reminder"
— Paul, 4★

Wellness Clinical Research Center

2714 West Ave, San Antonio, TX 78201

Southern Star Research Institute

★ 5.0
2833 Babcock Rd #206, San Antonio, TX 78229
(210) 581-2812
"They have been really great. Everything is tired so studies. It has helped my tummy been like I think 5 plus years"
— Virginia Zamora Davila, 5★

​Quality Research Inc

★ 4.9
303 W Sunset Rd Ste 102, San Antonio, TX 78209
(210) 864-8844
"Kaye is very knowledgeable, she explained everything about the result of our fibroscan. She took her time to answer all our questions and gave us re…"
— Rose Alonzo, 5★

Pinnacle Clinical Research

★ 4.7
5109 Medical Dr Ste 200, San Antonio, TX 78229
(210) 982-0320

Chromosome 18 Clinical Research Center

★ 4.8
7703 Floyd Curl Drive, Medical School Building, 5th Floor, Suite 533F, San Antonio, TX 78229
(210) 567-5321
"Great organization! They are doing wonderful work for the Chromosome 18 community, please support them in any way you can. Our family attended the an…"
— Jonathon Larson, 5★

Discovery Clinical Trials Corporate

★ 5.0
4242 Medical Dr Bldg 5, San Antonio, TX 78229
(855) 468-7788
"The staff at Discovery Clinical Trials are very professional and treat people with dignity and respect. They are thorough in explaining participation…"
— David X Casillas, 5★

Clinical trials in San Antonio: what's recruiting

The San Antonio area currently has 1,026 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to San Antonio, the most active research areas are:

  • Cancer & Oncology10 studies
  • Liver & Kidney3 studies
  • Heart & Vascular2 studies
  • Lungs & Breathing2 studies
  • Brain & Mental Health2 studies

Every listing shows the study phase, the recruiting site and its distance from San Antonio, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in San Antonio

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

San Antonio participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in San Antonio safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in San Antonio, TX?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in San Antonio?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in San Antonio typically complete one or two studies per year.

Paid clinical trials near San Antonio

Other metros within reach

Austin, TX723 Killeen, TX102 Corpus Christi, TX60 Laredo, TX23 Waco, TX52 College Station, TX46 Houston, TX3,067 McAllen, TX136

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in San Antonio Chronic Kidney Disease (HealthMatch) in San Antonio Bladder Issues Due To Spinal Cord Injury in San Antonio All conditions

More of TX

Houston3,067 Pasadena3,004 Irving1,967 Grand Prairie1,935 Dallas1,857 Arlington1,856 Garland1,818 Plano1,809 Frisco1,808 Mesquite1,759 Austin723

New paid studies open every week

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