Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TX/McAllen
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in McAllen, TX

Studies commonly pay $75 to $4,500 per completed study

136 clinical trials are currently recruiting participants within 30 miles of McAllen. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

136studies recruiting
7+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near McAllen right now

Top 25 of 136 recruiting studies, sorted by proximity — each links to its official registry page

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis Phase 2 Interventional 168 participants sought
Gamma Medical Research — McAllen, Texas (1.8 mi) · Sponsor: R1 Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06712654)

Phase 2 Study of ADX-038 in Participants With Geographic Atrophy

Geographic Atrophy Secondary to Age-related Macular Degeneration Phase 2 Interventional 240 participants sought
ADARx Clinical Site — McAllen, Texas (1.8 mi) · Sponsor: ADARx Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06990269)

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Cardiovascular Risk, Acute Myocardial Infarction (AMI) Phase 3 Interventional 10,000 participants sought
HCA Research Institute — McAllen, Texas (1.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT06118281)

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Percutaneous Coronary Intervention, Peripheral Endovascular Intervention Phase 4 Interventional 6,000 participants sought
DHR Health Institute for Research — McAllen, Texas (1.8 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT06909565)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
Nova Oncology — McAllen, Texas (1.8 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

Atopic Dermatitis N/A Observational 1,000 participants sought
Galderma Investigational Site 7062 — Edinburg, Texas (7.4 mi) · Sponsor: Galderma R&D
See eligibility & contact on ClinicalTrials.gov (NCT06988605)

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis, Ulcerative Colitis Chronic Phase 2 Interventional 143 participants sought
DHR Health Gastroenterology - Edinburg — Edinburg, Texas (7.4 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT06598943)

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Atherosclerotic Cardiovascular Disease, Overweight Phase 3 Interventional 12,800 participants sought
Biopharma Informatic-McAllen — McAllen, Texas (1.8 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037433)

Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

Urothelial Cancer, Advanced/Metastatic Urothelial Cancer Phase 1, Phase 2 Interventional 132 participants sought
Texas Oncology - Central/South Texas — McAllen, Texas (1.8 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07421700)

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

Geographic Atrophy, Macular Degeneration N/A Observational 500 participants sought
Valley Retina Institute — McAllen, Texas (1.8 mi) · Sponsor: Astellas Pharma Global Development, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06779773)

A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active Idiopathic Inflammatory Myopathies [Dermatomyositis (DM) and Polymyositis (PM)]

Myositis Phase 3 Interventional 318 participants sought
Pulmonary and Sleep Center of the Valley — Weslaco, Texas (16.5 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT05895786)

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

Breast Cancer, Metastatic Breast Cancer Phase 3 Interventional 404 participants sought
Texas Oncology McAllen — McAllen, Texas (1.8 mi) · Sponsor: BriaCell Therapeutics Corporation
See eligibility & contact on ClinicalTrials.gov (NCT06072612)

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

Non-small Cell Carcinoma, Non-Small Cell Lung Cancer Metastatic Phase 3 Interventional 680 participants sought
Texas Oncology -Central South — McAllen, Texas (1.8 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07144280)

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Stage III Colon Cancer Phase 2, Phase 3 Interventional 1,912 participants sought
STCC at DHR Health Institute for Research and Development — Edinburg, Texas (7.4 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05174169)

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

Osteoarthritis, Overweight or Obesity Phase 3 Interventional 900 participants sought
Texas Valley Clinical Research — Weslaco, Texas (16.5 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07353931)

A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple Sclerosis Who Switch From an Approved Anti-CD20 Therapy

Multiple Sclerosis Phase 4 Interventional 100 participants sought
DHR Health MS Center — McAllen, Texas (1.8 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07609719)

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

Ventricular Ejection Fraction, LVF N/A Observational 2,000 participants sought
South Heart Clinic — Weslaco, Texas (16.5 mi) · Sponsor: Peerbridge Health, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06699056)

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Obesity, Heart Failure Phase 3 Interventional 5,610 participants sought
Biopharma Informatic, LLC — McAllen, Texas (1.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07567001)

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

Obesity or Overweight Phase 3 Interventional 300 participants sought
South Texas Research Institute — Edinburg, Texas (7.4 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07575399)

Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers

Diabetic Foot Ulcer N/A Interventional 450 participants sought
Futuro Clinical Trials, LLC — McAllen, Texas (1.8 mi) · Sponsor: Piomic Medical
See eligibility & contact on ClinicalTrials.gov (NCT05758545)

REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults

Venous Thromboembolism (VTE) Phase 3 Interventional 2,000 participants sought
Futuro Clinical Trials — McAllen, Texas (1.8 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07015905)

Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

Pneumococcal Immunization, Healthy Volunteers Phase 3 Interventional 2,195 participants sought
PAS Research - Children's Care Clinic- Site Number : 8400035 — Edinburg, Texas (7.4 mi) · Sponsor: Sanofi
See eligibility & contact on ClinicalTrials.gov (NCT07348692)
Actively enrolling

Studies you may be able to join near McAllen

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in McAllen

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

DHR Health Institute for Research and Development

★ 4.0
1000 E Dove Ave Ste 200, McAllen, TX 78504
(956) 362-2390
"Staff is very friendly and great services"
— Ralphie Steinke, 5★

Rio Grande Valley Clinical Research Institute

★ 5.0
1002 W Sam Houston Blvd Ste 5, Pharr, TX 78577
(956) 342-2626
"Great doctor's great work thank you guys"
— Mario Reyna, 5★

Elevate Clinical Research - McAllen

★ 5.0
1020 Zinnia Ave W, McAllen, TX 78504
(956) 709-8567
"Great experience participating in a clinical study. The staff were friendly, professional, and always treated me with respect. They made the entire p…"
— Mando MTZ, 5★

Futuro Clinical Trials, LLC

★ 5.0
900 Lindberg Ave, McAllen, TX 78501
(956) 999-8399
"Super friendly professional and answered all my questions and cleared any concerns. Thanks again!!"
— Moises Arjona Jr, 5★

McAllen Research

★ 5.0
1104 W Sam Houston Blvd Ste B, Pharr, TX 78577
(956) 223-1050
"Definitely recommend, they are the best at what they do , super friendly and helpful staff always willing to go the extra mile ❤️"
— michael reyna, 5★

Discovery Clinical Trials - Mission

★ 4.8
1506 E Griffin Pkwy, Mission, TX 78572
(855) 468-7788
"Terrible experience. I was given a phony debit card as a compensation on 01/26/26. The clinic didn’t do the right thing in putting my information so …"
— Jose Sotello, 1★

Texas Valley Clinical Research

★ 5.0
1300 S Bryan Rd Unit 107, Mission, TX 78572
(956) 379-6866
"The staff is very informative and caring. They truly listen to any questions you have and are always ready to help you. I feel very comfortable with …"
— Diana Perez, 5★

Clinical trials in McAllen: what's recruiting

The McAllen area currently has 136 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to McAllen, the most active research areas are:

  • Cancer & Oncology7 studies
  • Diabetes & Metabolism6 studies
  • Heart & Vascular5 studies
  • Immune & Skin3 studies
  • Liver & Kidney2 studies

Every listing shows the study phase, the recruiting site and its distance from McAllen, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in McAllen

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

McAllen participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in McAllen safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in McAllen, TX?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in McAllen?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of McAllen.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in McAllen typically complete one or two studies per year.

Paid clinical trials near McAllen

Other metros within reach

Brownsville, TX61 Corpus Christi, TX60 Laredo, TX23 San Antonio, TX1,026 Austin, TX723 Galveston, TX203 Houston, TX3,067 Pasadena, TX3,004

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in McAllen Bladder Issues Due To Spinal Cord Injury in McAllen All conditions

More of TX

Houston3,067 Pasadena3,004 Irving1,967 Grand Prairie1,935 Dallas1,857 Arlington1,856 Garland1,818 Plano1,809 Frisco1,808 Mesquite1,759 San Antonio1,026 Austin723

New paid studies open every week

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