Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TX/McAllen
Updated October 2026 from ClinicalTrials.gov

Paid Clinical Trials in McAllen, TX

Studies commonly pay $75 to $4,500 per completed study

135 clinical trials are currently recruiting participants within 30 miles of McAllen. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

135studies recruiting
7+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near McAllen right now

Top 25 of 135 recruiting studies, sorted by proximity — each links to its official registry page

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

Relapsing Multiple Sclerosis, Multiple Sclerosis N/A Observational 2,000 participants sought
TG Therapeutics Investigational Trial Site — Edinburg, Texas (7.4 mi) · Sponsor: TG Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06433752)

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Cardiovascular Risk, Acute Myocardial Infarction (AMI) Phase 3 Interventional 10,000 participants sought
HCA Research Institute — McAllen, Texas (1.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT06118281)

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

Ventricular Ejection Fraction, LVF N/A Observational 2,000 participants sought
South Heart Clinic — Weslaco, Texas (16.5 mi) · Sponsor: Peerbridge Health, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06699056)

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

Overweight, Obesity Phase 3 Interventional 900 participants sought
Texas Valley Clinical Research (TVCR) - Mission — Mission, Texas (4.9 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07392190)

A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus

Systemic Lupus Erythematosus Phase 3 Interventional 245 participants sought
Research Site — Edinburg, Texas (7.4 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07430306)

A Randomized Control Trial of Conversations Advancing Resilience and Empowerment (CARE) Intervention

Quality of Life, Health Promotion N/A Interventional 200 participants sought
The University of Texas at Rio Grande Valley — Edinburg, Texas (7.4 mi) · Sponsor: University of Texas Rio Grande Valley
See eligibility & contact on ClinicalTrials.gov (NCT07698964)

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

NASH With Fibrosis, MASH With Fibrosis Phase 3 Interventional 1,650 participants sought
Akero Clinical Study Site — McAllen, Texas (1.8 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06215716)

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis Phase 3 Interventional 762 participants sought
89bio Clinical Study Site — Edinburg, Texas (7.4 mi) · Sponsor: 89bio, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06419374)

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

Type 2 Diabetes, Cortisol Excess Phase 2 Interventional 1,500 participants sought
Texas Valley Clinical Research - Mission, TX — Mission, Texas (4.9 mi) · Sponsor: Sparrow Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07296484)

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Heart Failure Phase 3 Interventional 11,300 participants sought
Research Site — McAllen, Texas (1.8 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06677060)

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Atherosclerotic Cardiovascular Disease, Overweight Phase 3 Interventional 12,800 participants sought
Biopharma Informatic-McAllen — McAllen, Texas (1.8 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037433)

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Phase 3 Interventional 247 participants sought
STCC at DHR Health Institute for Research and Development — Edinburg, Texas (7.4 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04269902)

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

Metastatic Non-small Cell Lung Cancer Phase 3 Interventional 734 participants sought
DHR Health Oncology Institute — Edinburg, Texas (7.4 mi) · Sponsor: NovoCure GmbH
See eligibility & contact on ClinicalTrials.gov (NCT06216301)

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought
Valley Retina Institute, PA — McAllen, Texas (1.8 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07553429)

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

Progressive Pulmonary Fibrosis, Interstitial Lung Disease Phase 3 Interventional 698 participants sought
A & A Research Consultants, LLC — McAllen, Texas (1.8 mi) · Sponsor: United Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT05943535)

Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain

Chemotherapy Induced Neuropathic Pain, Chemotherapy Induced Pain Neuropathy Phase 2 Interventional 240 participants sought
Central Recruiting Site — McAllen, Texas (1.8 mi) · Sponsor: Dogwood Therapeutics Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06848348)

A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine and a Marketed Measles, Mumps and Rubella Vaccine When Administered as Intramuscular Injection to Healthy Children 12 to 15 Months of Age

Chickenpox Phase 3 Interventional 911 participants sought
GSK Investigational Site — Pharr, Texas (4.4 mi) · Sponsor: GlaxoSmithKline
See eligibility & contact on ClinicalTrials.gov (NCT06855160)

Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Syndrome

Cushing Syndrome Phase 2 Interventional 12 participants sought
Texas Valley Clinical Research — Weslaco, Texas (16.5 mi) · Sponsor: RECORDATI GROUP
See eligibility & contact on ClinicalTrials.gov (NCT03708900)

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

Cigarette Smoking-Related Carcinoma Phase 3 Interventional 600 participants sought
STCC at DHR Health Institute for Research and Development — Edinburg, Texas (7.4 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05008848)

Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

Malignant Solid Neoplasm N/A Observational 2,062 participants sought
STCC at DHR Health Institute for Research and Development — Edinburg, Texas (7.4 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT04871542)

A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)

Metabolic Dysfunction-associated Steatohepatitis Phase 2 Interventional 160 participants sought
South Texas Research Institute (STRI) — Edinburg, Texas (7.4 mi) · Sponsor: Eccogene
See eligibility & contact on ClinicalTrials.gov (NCT07288138)
Actively enrolling

Studies you may be able to join near McAllen

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in McAllen

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

DHR Health Institute for Research and Development

★ 4.0
1000 E Dove Ave Ste 200, McAllen, TX 78504
(956) 362-2390
"Staff is very friendly and great services"
— Ralphie Steinke, 5★

Rio Grande Valley Clinical Research Institute

★ 5.0
1002 W Sam Houston Blvd Ste 5, Pharr, TX 78577
(956) 342-2626
"Great doctor's great work thank you guys"
— Mario Reyna, 5★

Elevate Clinical Research - McAllen

★ 5.0
1020 Zinnia Ave W, McAllen, TX 78504
(956) 709-8567
"Great experience participating in a clinical study. The staff were friendly, professional, and always treated me with respect. They made the entire p…"
— Mando MTZ, 5★

Futuro Clinical Trials, LLC

★ 5.0
900 Lindberg Ave, McAllen, TX 78501
(956) 999-8399
"Super friendly professional and answered all my questions and cleared any concerns. Thanks again!!"
— Moises Arjona Jr, 5★

McAllen Research

★ 5.0
1104 W Sam Houston Blvd Ste B, Pharr, TX 78577
(956) 223-1050
"Definitely recommend, they are the best at what they do , super friendly and helpful staff always willing to go the extra mile ❤️"
— michael reyna, 5★

Discovery Clinical Trials - Mission

★ 4.8
1506 E Griffin Pkwy, Mission, TX 78572
(855) 468-7788
"Terrible experience. I was given a phony debit card as a compensation on 01/26/26. The clinic didn’t do the right thing in putting my information so …"
— Jose Sotello, 1★

Texas Valley Clinical Research

★ 5.0
1300 S Bryan Rd Unit 107, Mission, TX 78572
(956) 379-6866
"The staff is very informative and caring. They truly listen to any questions you have and are always ready to help you. I feel very comfortable with …"
— Diana Perez, 5★

Clinical trials in McAllen: what's recruiting

The McAllen area currently has 135 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to McAllen, the most active research areas are:

  • Diabetes & Metabolism6 studies
  • Cancer & Oncology4 studies
  • Heart & Vascular4 studies
  • Liver & Kidney3 studies
  • Immune & Skin1 studies

Every listing shows the study phase, the recruiting site and its distance from McAllen, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in McAllen

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

McAllen participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in McAllen safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in McAllen, TX?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in McAllen?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of McAllen.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in McAllen typically complete one or two studies per year.

Paid clinical trials near McAllen

Other metros within reach

Brownsville, TX62 Corpus Christi, TX68 Laredo, TX22 San Antonio, TX1,018 Austin, TX748 Galveston, TX202 Houston, TX3,066 Pasadena, TX3,004

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in McAllen Bladder Issues Due To Spinal Cord Injury in McAllen All conditions

More of TX

Houston3,066 Pasadena3,004 Irving2,008 Grand Prairie1,979 Arlington1,892 Dallas1,890 Garland1,849 Plano1,841 Frisco1,840 Mesquite1,792 San Antonio1,018 Austin748

New paid studies open every week

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