Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TX/McAllen
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in McAllen, TX

Studies commonly pay $75 to $4,500 per completed study

139 clinical trials are currently recruiting participants within 30 miles of McAllen. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

139studies recruiting
7+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near McAllen right now

Top 25 of 139 recruiting studies, sorted by proximity — each links to its official registry page

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

Type 2 Diabetes, Cortisol Excess Phase 2 Interventional 1,500 participants sought
Texas Valley Clinical Research - Mission, TX — Mission, Texas (4.9 mi) · Sponsor: Sparrow Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07296484)

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Cardiovascular Risk, Acute Myocardial Infarction (AMI) Phase 3 Interventional 10,000 participants sought
HCA Research Institute — McAllen, Texas (1.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT06118281)

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis Phase 3 Interventional 2,150 participants sought
Akero Clinical Study Site — Pharr, Texas (4.4 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06528314)

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

Ventricular Ejection Fraction, LVF N/A Observational 2,000 participants sought
South Heart Clinic — Weslaco, Texas (16.5 mi) · Sponsor: Peerbridge Health, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06699056)

A Randomized Control Trial of Conversations Advancing Resilience and Empowerment (CARE) Intervention

Quality of Life, Health Promotion N/A Interventional 200 participants sought
The University of Texas at Rio Grande Valley — Edinburg, Texas (7.4 mi) · Sponsor: University of Texas Rio Grande Valley
See eligibility & contact on ClinicalTrials.gov (NCT07698964)

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

Acute Ischemic Stroke Phase 3 Interventional 404 participants sought
DHR Health Institute for Research and Development — Edinburg, Texas (7.4 mi) · Sponsor: Mercy Health Ohio
See eligibility & contact on ClinicalTrials.gov (NCT05611242)

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Atherosclerotic Cardiovascular Disease, Overweight Phase 3 Interventional 12,800 participants sought
Biopharma Informatic-McAllen — McAllen, Texas (1.8 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037433)

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Diabetes Mellitus, Type 2, Hypertension Phase 3 Interventional 11,800 participants sought
Texas Valley Clinical Research — Weslaco, Texas (16.5 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07064473)

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

Metabolic Dysfunction-Associated Steatotic Liver Disease Phase 3 Interventional 4,500 participants sought
Biopharma Informatic, LLC — McAllen, Texas (1.8 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07165028)

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

Cigarette Smoking-Related Carcinoma Phase 3 Interventional 600 participants sought
STCC at DHR Health Institute for Research and Development — Edinburg, Texas (7.4 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05008848)

A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition

Metabolic Dysfunction-Associated SteatoHepatitis (MASH) Phase 2 Interventional 120 participants sought
Great Lakes Research Institute — Pharr, Texas (4.4 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT05519475)

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

Melanoma Phase 3 Interventional 560 participants sought
Texas Oncology - McAllen — McAllen, Texas (1.8 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06246916)

Phase 3 Study to Assess Efficacy, Safety & Tolerability of OCU410 For Geographic Atrophy Secondary to Dry AMD

Dry Age-related Macular Degeneration Phase 3 Interventional 237 participants sought
Valley Retina Institute — McAllen, Texas (1.8 mi) · Sponsor: Ocugen
See eligibility & contact on ClinicalTrials.gov (NCT07770828)

Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

Langerhans Cell Histiocytosis Phase 3 Interventional 124 participants sought
Vannie Cook Children's Clinic — McAllen, Texas (1.8 mi) · Sponsor: Baylor College of Medicine
See eligibility & contact on ClinicalTrials.gov (NCT02670707)

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

Overweight, Obesity Phase 3 Interventional 900 participants sought
Texas Valley Clinical Research (TVCR) - Mission — Mission, Texas (4.9 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07392190)

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

COPD (Chronic Obstructive Pulmonary Disease) Phase 3 Interventional 5,000 participants sought
Research Site — McAllen, Texas (1.8 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06283966)

Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain

Chemotherapy Induced Neuropathic Pain, Chemotherapy Induced Pain Neuropathy Phase 2 Interventional 240 participants sought
Central Recruiting Site — McAllen, Texas (1.8 mi) · Sponsor: Dogwood Therapeutics Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06848348)

A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus Phase 3 Interventional 1,200 participants sought
Research Site — Weslaco, Texas (16.5 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07662213)

Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

Malignant Solid Neoplasm N/A Observational 2,062 participants sought
STCC at DHR Health Institute for Research and Development — Edinburg, Texas (7.4 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT04871542)
Actively enrolling

Studies you may be able to join near McAllen

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in McAllen

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

DHR Health Institute for Research and Development

★ 4.0
1000 E Dove Ave Ste 200, McAllen, TX 78504
(956) 362-2390
"Staff is very friendly and great services"
— Ralphie Steinke, 5★

Rio Grande Valley Clinical Research Institute

★ 5.0
1002 W Sam Houston Blvd Ste 5, Pharr, TX 78577
(956) 342-2626
"Great doctor's great work thank you guys"
— Mario Reyna, 5★

Elevate Clinical Research - McAllen

★ 5.0
1020 Zinnia Ave W, McAllen, TX 78504
(956) 709-8567
"Great experience participating in a clinical study. The staff were friendly, professional, and always treated me with respect. They made the entire p…"
— Mando MTZ, 5★

Futuro Clinical Trials, LLC

★ 5.0
900 Lindberg Ave, McAllen, TX 78501
(956) 999-8399
"Super friendly professional and answered all my questions and cleared any concerns. Thanks again!!"
— Moises Arjona Jr, 5★

McAllen Research

★ 5.0
1104 W Sam Houston Blvd Ste B, Pharr, TX 78577
(956) 223-1050
"Definitely recommend, they are the best at what they do , super friendly and helpful staff always willing to go the extra mile ❤️"
— michael reyna, 5★

Discovery Clinical Trials - Mission

★ 4.8
1506 E Griffin Pkwy, Mission, TX 78572
(855) 468-7788
"Terrible experience. I was given a phony debit card as a compensation on 01/26/26. The clinic didn’t do the right thing in putting my information so …"
— Jose Sotello, 1★

Texas Valley Clinical Research

★ 5.0
1300 S Bryan Rd Unit 107, Mission, TX 78572
(956) 379-6866
"The staff is very informative and caring. They truly listen to any questions you have and are always ready to help you. I feel very comfortable with …"
— Diana Perez, 5★

Clinical trials in McAllen: what's recruiting

The McAllen area currently has 139 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to McAllen, the most active research areas are:

  • Diabetes & Metabolism8 studies
  • Cancer & Oncology6 studies
  • Heart & Vascular5 studies
  • Liver & Kidney5 studies
  • Lungs & Breathing2 studies

Every listing shows the study phase, the recruiting site and its distance from McAllen, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in McAllen

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

McAllen participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in McAllen safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in McAllen, TX?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in McAllen?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of McAllen.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in McAllen typically complete one or two studies per year.

Paid clinical trials near McAllen

Other metros within reach

Brownsville, TX63 Corpus Christi, TX65 Laredo, TX22 San Antonio, TX1,010 Austin, TX738 Galveston, TX204 Houston, TX3,069 Pasadena, TX3,010

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in McAllen Bladder Issues Due To Spinal Cord Injury in McAllen All conditions

More of TX

Houston3,069 Pasadena3,010 Irving1,988 Grand Prairie1,956 Arlington1,871 Dallas1,868 Garland1,830 Plano1,825 Frisco1,824 Mesquite1,771 San Antonio1,010 Austin738

New paid studies open every week

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