Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TX/McAllen
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in McAllen, TX

Studies commonly pay $75 to $4,500 per completed study

137 clinical trials are currently recruiting participants within 30 miles of McAllen. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

137studies recruiting
7+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near McAllen right now

Top 25 of 137 recruiting studies, sorted by proximity — each links to its official registry page

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought
Valley Retina Institute, PA — McAllen, Texas (1.8 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07553429)

A Randomized Control Trial of Conversations Advancing Resilience and Empowerment (CARE) Intervention

Quality of Life, Health Promotion N/A Interventional 200 participants sought
The University of Texas at Rio Grande Valley — Edinburg, Texas (7.4 mi) · Sponsor: University of Texas Rio Grande Valley
See eligibility & contact on ClinicalTrials.gov (NCT07698964)

A Study to Investigate Canvuparatide Compared With Placebo in Adult Patients With Hypoparathyroidism

Hypoparathyroidism Phase 3 Interventional 160 participants sought
MBX Biosciences Investigational Site — Weslaco, Texas (16.5 mi) · Sponsor: MBX Biosciences
See eligibility & contact on ClinicalTrials.gov (NCT07699471)

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism Phase 2, Phase 3 Interventional 2,800 participants sought
Texas Valley Clinical Research /ID# 261476 — Weslaco, Texas (16.5 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06345339)

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Atherosclerotic Cardiovascular Disease, Overweight Phase 3 Interventional 12,800 participants sought
Biopharma Informatic-McAllen — McAllen, Texas (1.8 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037433)

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Advanced Non-Small Cell Lung Cancer, Non-Small Cell Lung Cancer Phase 3 Interventional 1,410 participants sought
Texas Oncology - Central/South Texas — McAllen, Texas (1.8 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07222566)

EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

COVID-19 Phase 3 Interventional 160 participants sought
Biopharma Informatic, LLC — McAllen, Texas (1.8 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT05261139)

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis Phase 3 Interventional 1,350 participants sought
89bio Clinical Study Site — Edinburg, Texas (7.4 mi) · Sponsor: 89bio, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06318169)

A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio

Geographic Atrophy Secondary to Age-related Macular Degeneration Phase 2 Interventional 240 participants sought
Valley Retina Institute- McAllen (01076) — McAllen, Texas (1.8 mi) · Sponsor: Apellis Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07215390)

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

Metabolic Dysfunction Associated Steatohepatitis Phase 3 Interventional 1,590 participants sought
Biopharma Informatic LLC — McAllen, Texas (1.8 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT06632457)

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

Progressive Pulmonary Fibrosis, Interstitial Lung Disease Phase 3 Interventional 698 participants sought
A & A Research Consultants, LLC — McAllen, Texas (1.8 mi) · Sponsor: United Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT05943535)

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

High Risk Cardiovascular Disease, Hypertension Phase 3 Interventional 11,000 participants sought
Clinical Trial Site — McAllen, Texas (1.8 mi) · Sponsor: Alnylam Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07181109)

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

Overweight, Obesity Phase 3 Interventional 900 participants sought
Texas Valley Clinical Research (TVCR) - Mission — Mission, Texas (4.9 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07392190)

A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active Idiopathic Inflammatory Myopathies [Dermatomyositis (DM) and Polymyositis (PM)]

Myositis Phase 3 Interventional 318 participants sought
Pulmonary and Sleep Center of the Valley — Weslaco, Texas (16.5 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT05895786)

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

Breast Cancer, Metastatic Breast Cancer Phase 3 Interventional 404 participants sought
Texas Oncology McAllen — McAllen, Texas (1.8 mi) · Sponsor: BriaCell Therapeutics Corporation
See eligibility & contact on ClinicalTrials.gov (NCT06072612)

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

Obesity, Overweight Phase 2 Interventional 1,481 participants sought
Texas Valley Clinical Research — Weslaco, Texas (16.5 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT06143956)

Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers

Diabetic Foot Ulcer, Wagner Grade 1 - 2 Phase 1, Phase 2 Interventional 15 participants sought
Futuro Clinical Trials — McAllen, Texas (1.8 mi) · Sponsor: Eluciderm Inc
See eligibility & contact on ClinicalTrials.gov (NCT07396376)

A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus Phase 3 Interventional 1,200 participants sought
Research Site — Weslaco, Texas (16.5 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07662213)

A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease

Respiratory Syncytial Virus Infections Phase 2 Interventional 192 participants sought
DCT-McAllen Primary Care Research, LLC — McAllen, Texas (1.8 mi) · Sponsor: Shionogi
See eligibility & contact on ClinicalTrials.gov (NCT07214571)

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

Osteoarthritis, Overweight or Obesity Phase 3 Interventional 900 participants sought
Texas Valley Clinical Research — Weslaco, Texas (16.5 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07353931)

A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple Sclerosis Who Switch From an Approved Anti-CD20 Therapy

Multiple Sclerosis Phase 4 Interventional 100 participants sought
DHR Health MS Center — McAllen, Texas (1.8 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07609719)

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

End Stage Kidney Disease Phase 2, Phase 3 Interventional 3,110 participants sought
Gamma Medical Research, Inc. — McAllen, Texas (1.8 mi) · Sponsor: CSL Behring
See eligibility & contact on ClinicalTrials.gov (NCT05485961)
Actively enrolling

Studies you may be able to join near McAllen

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in McAllen

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

DHR Health Institute for Research and Development

★ 4.0
1000 E Dove Ave Ste 200, McAllen, TX 78504
(956) 362-2390
"Staff is very friendly and great services"
— Ralphie Steinke, 5★

Rio Grande Valley Clinical Research Institute

★ 5.0
1002 W Sam Houston Blvd Ste 5, Pharr, TX 78577
(956) 342-2626
"Great doctor's great work thank you guys"
— Mario Reyna, 5★

Elevate Clinical Research - McAllen

★ 5.0
1020 Zinnia Ave W, McAllen, TX 78504
(956) 709-8567
"Great experience participating in a clinical study. The staff were friendly, professional, and always treated me with respect. They made the entire p…"
— Mando MTZ, 5★

Futuro Clinical Trials, LLC

★ 5.0
900 Lindberg Ave, McAllen, TX 78501
(956) 999-8399
"Super friendly professional and answered all my questions and cleared any concerns. Thanks again!!"
— Moises Arjona Jr, 5★

McAllen Research

★ 5.0
1104 W Sam Houston Blvd Ste B, Pharr, TX 78577
(956) 223-1050
"Definitely recommend, they are the best at what they do , super friendly and helpful staff always willing to go the extra mile ❤️"
— michael reyna, 5★

Discovery Clinical Trials - Mission

★ 4.8
1506 E Griffin Pkwy, Mission, TX 78572
(855) 468-7788
"Terrible experience. I was given a phony debit card as a compensation on 01/26/26. The clinic didn’t do the right thing in putting my information so …"
— Jose Sotello, 1★

Texas Valley Clinical Research

★ 5.0
1300 S Bryan Rd Unit 107, Mission, TX 78572
(956) 379-6866
"The staff is very informative and caring. They truly listen to any questions you have and are always ready to help you. I feel very comfortable with …"
— Diana Perez, 5★

Clinical trials in McAllen: what's recruiting

The McAllen area currently has 137 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to McAllen, the most active research areas are:

  • Diabetes & Metabolism9 studies
  • Cancer & Oncology4 studies
  • Liver & Kidney4 studies
  • Heart & Vascular2 studies
  • Lungs & Breathing2 studies

Every listing shows the study phase, the recruiting site and its distance from McAllen, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in McAllen

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

McAllen participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in McAllen safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in McAllen, TX?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in McAllen?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of McAllen.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in McAllen typically complete one or two studies per year.

Paid clinical trials near McAllen

Other metros within reach

Brownsville, TX62 Corpus Christi, TX61 Laredo, TX21 San Antonio, TX1,023 Austin, TX736 Galveston, TX201 Houston, TX3,068 Pasadena, TX3,007

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in McAllen Bladder Issues Due To Spinal Cord Injury in McAllen All conditions

More of TX

Houston3,068 Pasadena3,007 Irving1,979 Grand Prairie1,947 Arlington1,866 Dallas1,864 Garland1,826 Plano1,817 Frisco1,816 Mesquite1,767 San Antonio1,023 Austin736

New paid studies open every week

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