Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TX/McKinney
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in McKinney, TX

Studies commonly pay $75 to $4,500 per completed study

457 clinical trials are currently recruiting participants within 30 miles of McKinney. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

457studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near McKinney right now

Top 25 of 457 recruiting studies, sorted by proximity — each links to its official registry page

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
UT Southwestern Clinical Center at Richardson/Plano — Richardson, Texas (17.9 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma Phase 2 Interventional 81 participants sought
UT Southwestern Clinical Center at Richardson/Plano — Richardson, Texas (17.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05112601)

Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8 Phase 3 Interventional 428 participants sought
UT Southwestern Clinical Center at Richardson/Plano — Richardson, Texas (17.9 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05646316)

A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

Diffuse Cutaneous Systemic Sclerosis Phase 2 Interventional 200 participants sought
Arthritis and Rheumatology Ins — Allen, Texas (6.8 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06470048)

Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS

COPD, Smoking N/A Interventional 290 participants sought
Metroplex Pulmonary & Sleep Center — McKinney, Texas (3.0 mi) · Sponsor: Philip Morris Products S.A.
See eligibility & contact on ClinicalTrials.gov (NCT07108166)

Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

Rheumatoid Arthritis, Systemic Lupus Erythematosus Phase 1 Interventional 48 participants sought
Research Site — Allen, Texas (6.8 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07201558)

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
Tekton Research — McKinney, Texas (3.0 mi) · Sponsor: Medtronic MiniMed, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07228117)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
UT Southwestern Clinical Center at Richardson/Plano — Richardson, Texas (17.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth in/Near Infected Bone Cavities

Periprosthetic Joint Infections N/A Interventional 204 participants sought
Carrollton regional Medical Center — Carrollton, Texas (21.5 mi) · Sponsor: Elute, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05361941)

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus Phase 3 Interventional 450 participants sought
Sl0044 50562 — Frisco, Texas (9.7 mi) · Sponsor: UCB Biopharma SRL
See eligibility & contact on ClinicalTrials.gov (NCT06617325)

Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients

Irritability Associated With Autism Spectrum Disorder Phase 3 Interventional 160 participants sought
AIM Trials — Plano, Texas (12.7 mi) · Sponsor: Intra-Cellular Therapies, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06690398)

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Metastatic Castration Sensitive Prostate Cancer (mCSPC), Hormone Sensitive Prostate Cancer Phase 3 Interventional 1,000 participants sought
University of Texas Southwestern Simmons Cancer Center - Richardson/Plano — Richardson, Texas (17.9 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07028853)

A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia

Schizophrenia Phase 2 Interventional 268 participants sought
Pillar Clinical Research - Richardson /ID# 275715 — Richardson, Texas (17.9 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT07145918)

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate Phase 2 Interventional 1,431 participants sought
GI Alliance - Garland — Garland, Texas (20.0 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07415044)

A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis

Generalized Myasthenia Gravis Phase 2, Phase 3 Interventional 12 participants sought
Neurology Rare Disease Center — Denton, Texas (27.0 mi) · Sponsor: argenx
See eligibility & contact on ClinicalTrials.gov (NCT06392386)

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis With Cardiomyopathy Phase 3 Interventional 1,750 participants sought
Clinical Trial Site — Plano, Texas (12.7 mi) · Sponsor: Alnylam Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07052903)

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

Aortic Valve Insufficiency, Aortic Valve Stenosis N/A Interventional 200 participants sought
The Heart Hospital Baylor Plano — Plano, Texas (12.7 mi) · Sponsor: Edwards Lifesciences
See eligibility & contact on ClinicalTrials.gov (NCT05172973)
Actively enrolling

Studies you may be able to join near McKinney

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in McKinney

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

DelRicht Research of Dallas Clinical Trials

★ 4.9
1050 S Coit Rd Ste 10, Prosper, TX 75078
(972) 807-5787
"Working with both Adriana and Kelsey was a great experience. The care I received as well as education was terrific!"
— Dan Chase, 5★

North Dallas Research Associates

★ 5.0
4201 Medical Center Dr Ste 380, McKinney, TX 75069
(972) 562-2345

North Texas Center for Clinical Research

★ 5.0
3880 Parkwood Blvd, Frisco, TX 75034
(214) 618-0220
"Aly, Summer and Keisha are awesome. Very little waiting time and the staff are always there to welcome you with a smile."
— Brett Kozlowski, 5★

Tekton Research

4201 Medical Center Dr Ste 250, McKinney, TX 75069
(972) 777-6011

ACRC Trials

★ 4.8
5655 W Spring Creek Pkwy Ste 125, Plano, TX 75024
(469) 382-3949
"Was in a study with ACRC and it was great! Thorough explanations for the study, and super friendly coordinator who called periodically to see how th…"
— Kara B, 5★

The ENT & Allergy Centers of Texas | McKinney

★ 4.5
5220 W University Dr Ste 150, McKinney, TX 75071
(972) 984-1050
"Our son has been a patient since he was about one, now five and a half and they have always had such patience with him as well as know how to make me…"
— Kayla, 5★

Pillar Clinical Research, Richardson, Texas

★ 4.8
630 N Coit Rd Ste.2200, Richardson, TX 75080
(214) 396-4844
"Berry beautiful place valm the Staff are very admint about about take care of you it was a beautiful experience I love you all. I would definitely re…"
— Vig Dall, 5★

Future Med Clinical Research

5072 W Plano Pkwy #190, Plano, TX 75093
(972) 312-7285

Discovery Clinical Trials - Dallas

★ 4.9
7777 Forest Ln Bldg D, Suite 1200, Dallas, TX 75230
(855) 468-7788
"The office staff are so professional and caring just like family well educated and explained the procedures love being a part of this trial❤️❤️❤️"
— delia anthony, 5★

Clinical trials in McKinney: what's recruiting

The McKinney area currently has 457 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to McKinney, the most active research areas are:

  • Cancer & Oncology5 studies
  • Immune & Skin4 studies
  • Heart & Vascular4 studies
  • Lungs & Breathing1 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from McKinney, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in McKinney

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

McKinney participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in McKinney?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in McKinney, TX?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in McKinney?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of McKinney.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in McKinney typically complete one or two studies per year.

Paid clinical trials near McKinney

Other metros within reach

Frisco, TX1,824 Plano, TX1,825 Garland, TX1,830 Dallas, TX1,868 Mesquite, TX1,771 Irving, TX1,988 Denton, TX379 Grand Prairie, TX1,956

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in McKinney Chronic Kidney Disease (HealthMatch) in McKinney Bladder Issues Due To Spinal Cord Injury in McKinney All conditions

More of TX

Houston3,069 Pasadena3,010 Irving1,988 Grand Prairie1,956 Arlington1,871 Dallas1,868 Garland1,830 Plano1,825 Frisco1,824 Mesquite1,771 San Antonio1,010 Austin738

New paid studies open every week

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