Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CO/Colorado Springs
Updated October 2026 from ClinicalTrials.gov

Paid Clinical Trials in Colorado Springs, CO

Studies commonly pay $75 to $4,500 per completed study

205 clinical trials are currently recruiting participants within 30 miles of Colorado Springs. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

205studies recruiting
9+research centers nearby
7condition categories
Live from the NIH registry

Studies recruiting near Colorado Springs right now

Top 25 of 205 recruiting studies, sorted by proximity — each links to its official registry page

A Long-Term Study of ALKS 2680 in Subjects With Narcolepsy and Idiopathic Hypersomnia

Narcolepsy Type 1, Narcolepsy Type 2 Phase 2, Phase 3 Interventional 786 participants sought
Alkermes Investigational Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: Alkermes, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06767683)

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate Phase 2 Interventional 1,431 participants sought
Peak Gastroenterology Associates — Colorado Springs, Colorado (4.0 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07415044)

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Carcinoma Phase 3 Interventional 804 participants sought
Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT04423211)

Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder

Schizophrenia, Bipolar I Disorder Phase 3 Interventional 220 participants sought
Alkermes Investigator Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: Alkermes, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05303064)

A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

Neuroblastoma Recurrent Phase 2 Interventional 54 participants sought
Children's Hospital of Colorado — Colorado Springs, Colorado (4.0 mi) · Sponsor: St. Jude Children's Research Hospital
See eligibility & contact on ClinicalTrials.gov (NCT07085338)

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought
Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04251052)

Effects of Physical and Psychosocial Stress on Functional Hypothalamic Amenorrhea in Exercising Women

Amenorrhea Secondary N/A Interventional 54 participants sought
University of Colorado Colorado Springs — Colorado Springs, Colorado (4.0 mi) · Sponsor: University of Colorado, Colorado Springs
See eligibility & contact on ClinicalTrials.gov (NCT05967819)

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

Relapsing Multiple Sclerosis, Multiple Sclerosis N/A Observational 2,000 participants sought
TG Therapeutics Investigational Trial Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: TG Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06433752)

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

Bipolar Disorder Type I With Mania Phase 3 Interventional 450 participants sought
Local Institution - 0203 — Colorado Springs, Colorado (4.0 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT06929273)

Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis

Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps N/A Interventional 300 participants sought
Colorado ENT & Allergy — Colorado Springs, Colorado (4.0 mi) · Sponsor: Airiver Medical, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07290140)

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis Phase 3 Interventional 2,150 participants sought
Akero Clinical Study Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06528314)

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 Phase 2 Interventional 474 participants sought
UCHealth Memorial Hospital Central — Colorado Springs, Colorado (4.0 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06632977)

Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps

Chronic Rhinosinusitis Without Nasal Polyps Phase 3 Interventional 84 participants sought
Colorado ENT & Allergy — Colorado Springs, Colorado (4.0 mi) · Sponsor: Optinose US Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06850805)

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma Phase 3 Interventional 255 participants sought
UCHealth Memorial Hospital Central — Colorado Springs, Colorado (4.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07198074)

JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

Non-Small Cell Lung Cancer Phase 3 Interventional 272 participants sought
Penrose Cancer Center — Colorado Springs, Colorado (4.0 mi) · Sponsor: University of Texas Southwestern Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT02468024)

A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

Crohn Disease Phase 3 Interventional 530 participants sought
Peak Gastroenterology Associates — Colorado Springs, Colorado (4.0 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07499232)

A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration

Neovascular Age-related Macular Degeneration, nAMD Phase 3 Interventional 304 participants sought
Retina Consultants of Southern Colorado (Colorado Springs)- RCA — Colorado Springs, Colorado (4.0 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07614776)

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

Asthma Phase 2 Interventional 531 participants sought
Asthma & Allergy Associates - Colorado Springs — Colorado Springs, Colorado (4.0 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07219173)

A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

Idiopathic Hypersomnia Phase 3 Interventional 248 participants sought
Delta Waves LLC — Colorado Springs, Colorado (4.0 mi) · Sponsor: Harmony Biosciences Management, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07500090)

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Phase 3 Interventional 247 participants sought
Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04269902)

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum N/A Interventional 9,500 participants sought
Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05080673)

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma, Stage I Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8 Phase 3 Interventional 228 participants sought
UCHealth Memorial Hospital Central — Colorado Springs, Colorado (4.0 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06992427)

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Intestinal Neoplasms, Gastrointestinal Neoplasms Phase 3 Interventional 800 participants sought
Rocky Mountain Cancer Centers, LLP — Colorado Springs, Colorado (4.0 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07222800)
Actively enrolling

Studies you may be able to join near Colorado Springs

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Colorado Springs

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Legacy Clinical Trials of Colorado Springs

★ 5.0
2960 N Circle Dr #125, Colorado Springs, CO 80909
(719) 387-7572

Skylight Health Research

★ 5.0
3100 N Academy Blvd Ste 115, Colorado Springs, CO 80917
(719) 301-7162
"I did the COVID study, the staff is awesome! All very nice and professional."
— IShii Graphics and Media, 5★

MCB Clinical Research Centers

★ 4.1
110 S Parkside Dr, Colorado Springs, CO 80910
(719) 634-6576
"I’ve been coming to this clinical research center for years, and the improvement is honestly impressive. Compared to 4/5 years ago, the facility is n…"
— Holly M, 5★

Optum - Clinical Research

6340 Barnes Rd, Colorado Springs, CO 80922
(844) 761-9865

Lane Center for Academic Health Sciences at UCCS

★ 4.5
4863 N Nevada Ave, Colorado Springs, CO 80918
"Super friendly and helpful staff."
— Michael Nicewonger, 5★

Lynn Institute of the Rockies

★ 5.0
2855 Dublin Blvd, Colorado Springs, CO 80918
(719) 636-3784
"Friendly staff! It's been a pleasure being part of the trials with this group."
— Jacqueline Hjelm, 5★

Ascend Clinical

★ 5.0
9925 Federal Dr, Colorado Springs, CO 80921
(719) 538-1462

WellLife Medical Centers

★ 4.3
975 Garden of the Gods Rd, Colorado Springs, CO 80907
(719) 694-8782

Delta Waves

★ 4.2
5835 Lehman Dr #101, Colorado Springs, CO 80918
(719) 262-9283
"They were amazing. On our road trip, we had to make an unplanned stop here for a piece of medical equipment that I needed. I highly recommend them!"
— Dawn Gordon, 5★

Clinical trials in Colorado Springs: what's recruiting

The Colorado Springs area currently has 205 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Colorado Springs, the most active research areas are:

  • Cancer & Oncology9 studies
  • Immune & Skin2 studies
  • Lungs & Breathing2 studies
  • Brain & Mental Health2 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Colorado Springs, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Colorado Springs

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Colorado Springs participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Colorado Springs pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Colorado Springs safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Colorado Springs, CO?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Colorado Springs?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Colorado Springs.

Paid clinical trials near Colorado Springs

Other metros within reach

Aurora, CO1,571 Denver, CO1,604 Lakewood, CO1,604 Thornton, CO1,608 Greeley, CO157 Fort Collins, CO155 Grand Junction, CO50 Albuquerque, NM345

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Colorado Springs Bladder Issues Due To Spinal Cord Injury in Colorado Springs All conditions

More of CO

Thornton1,608 Denver1,604 Lakewood1,604 Aurora1,571 Greeley157 Fort Collins155 Grand Junction50

New paid studies open every week

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