Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CO/Colorado Springs
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Colorado Springs, CO

Studies commonly pay $75 to $4,500 per completed study

208 clinical trials are currently recruiting participants within 30 miles of Colorado Springs. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

208studies recruiting
9+research centers nearby
7condition categories
Live from the NIH registry

Studies recruiting near Colorado Springs right now

Top 25 of 208 recruiting studies, sorted by proximity — each links to its official registry page

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED

Persistent Corneal Epithelial Defect Phase 2 Interventional 84 participants sought
Glaukos Investigative Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: Glaukos Corporation
See eligibility & contact on ClinicalTrials.gov (NCT05966493)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06129864)

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma Phase 3 Interventional 1,524 participants sought
UCHealth Memorial Hospital Central — Colorado Springs, Colorado (4.0 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT07200830)

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer Phase 3 Interventional 600 participants sought
UC Health Oncology Research — Colorado Springs, Colorado (4.0 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06793215)

A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

Neuroblastoma Recurrent Phase 2 Interventional 54 participants sought
Children's Hospital of Colorado — Colorado Springs, Colorado (4.0 mi) · Sponsor: St. Jude Children's Research Hospital
See eligibility & contact on ClinicalTrials.gov (NCT07085338)

Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy

Ig-E Mediated Food Allergy Phase 2 Interventional 100 participants sought
Asthma & Allergy Associates, P.C. — Colorado Springs, Colorado (4.0 mi) · Sponsor: RAPT Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07220811)

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis Phase 3 Interventional 2,150 participants sought
Akero Clinical Study Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06528314)

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

Psychosis Associated With Alzheimer's Disease Phase 3 Interventional 410 participants sought
Local Institution - 1014 — Colorado Springs, Colorado (4.0 mi) · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See eligibility & contact on ClinicalTrials.gov (NCT05511363)

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Breast Carcinoma, Colorectal Carcinoma N/A Observational 2,000 participants sought
Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT06418204)

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Primary Open Angle Glaucoma Phase 3 Interventional 130 participants sought
Colorado Eye Institute /ID# 277072 — Colorado Springs, Colorado (4.0 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06822738)

Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps

Chronic Rhinosinusitis Without Nasal Polyps Phase 3 Interventional 84 participants sought
Colorado ENT & Allergy — Colorado Springs, Colorado (4.0 mi) · Sponsor: Optinose US Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06850805)

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Arrhythmia, Bradycardia N/A Observational 20,000 participants sought
Research site — Colorado Springs, Colorado (4.0 mi) · Sponsor: Medtronic
See eligibility & contact on ClinicalTrials.gov (NCT00271180)

JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

Non-Small Cell Lung Cancer Phase 3 Interventional 272 participants sought
Penrose Cancer Center — Colorado Springs, Colorado (4.0 mi) · Sponsor: University of Texas Southwestern Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT02468024)

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

Viral Lung Infection and Acute Respiratory Failure Phase 3 Interventional 3,527 participants sought
Research Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT05624450)

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

Colitis, Ulcerative Phase 3 Interventional 882 participants sought
Peak Gastroenterology Associates — Colorado Springs, Colorado (4.0 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07196748)

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 626 participants sought
Local Institution - 007-872-C — Colorado Springs, Colorado (4.0 mi) · Sponsor: Mirati Therapeutics Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04613596)

Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis

Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps N/A Interventional 300 participants sought
Colorado ENT & Allergy — Colorado Springs, Colorado (4.0 mi) · Sponsor: Airiver Medical, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07290140)

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

Obesity, Overweight Phase 3 Interventional 125 participants sought
Children's Hospital Colorado — Colorado Springs, Colorado (4.0 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT06672549)

A Study to Evaluate the Efficacy and Safety of Maintenance Ublituximab Following Induction With Efgartigimod Administration in Participants With Myasthenia Gravis (MG)

Myasthenia Gravis Phase 2 Interventional 120 participants sought
TG Therapeutics Investigational Trial Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: TG Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07673744)

Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

Malignant Solid Neoplasm N/A Observational 2,062 participants sought
Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT04871542)
Actively enrolling

Studies you may be able to join near Colorado Springs

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Colorado Springs

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Legacy Clinical Trials of Colorado Springs

★ 5.0
2960 N Circle Dr #125, Colorado Springs, CO 80909
(719) 387-7572

Skylight Health Research

★ 5.0
3100 N Academy Blvd Ste 115, Colorado Springs, CO 80917
(719) 301-7162
"I did the COVID study, the staff is awesome! All very nice and professional."
— IShii Graphics and Media, 5★

MCB Clinical Research Centers

★ 4.1
110 S Parkside Dr, Colorado Springs, CO 80910
(719) 634-6576
"I’ve been coming to this clinical research center for years, and the improvement is honestly impressive. Compared to 4/5 years ago, the facility is n…"
— Holly M, 5★

Optum - Clinical Research

6340 Barnes Rd, Colorado Springs, CO 80922
(844) 761-9865

Lane Center for Academic Health Sciences at UCCS

★ 4.5
4863 N Nevada Ave, Colorado Springs, CO 80918
"Super friendly and helpful staff."
— Michael Nicewonger, 5★

Lynn Institute of the Rockies

★ 5.0
2855 Dublin Blvd, Colorado Springs, CO 80918
(719) 636-3784
"Friendly staff! It's been a pleasure being part of the trials with this group."
— Jacqueline Hjelm, 5★

Ascend Clinical

★ 5.0
9925 Federal Dr, Colorado Springs, CO 80921
(719) 538-1462

WellLife Medical Centers

★ 4.3
975 Garden of the Gods Rd, Colorado Springs, CO 80907
(719) 694-8782

Delta Waves

★ 4.2
5835 Lehman Dr #101, Colorado Springs, CO 80918
(719) 262-9283
"They were amazing. On our road trip, we had to make an unplanned stop here for a piece of medical equipment that I needed. I highly recommend them!"
— Dawn Gordon, 5★

Clinical trials in Colorado Springs: what's recruiting

The Colorado Springs area currently has 208 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Colorado Springs, the most active research areas are:

  • Cancer & Oncology10 studies
  • Immune & Skin2 studies
  • Heart & Vascular2 studies
  • Lungs & Breathing2 studies
  • Liver & Kidney2 studies

Every listing shows the study phase, the recruiting site and its distance from Colorado Springs, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Colorado Springs

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Colorado Springs participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Colorado Springs pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Colorado Springs safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Colorado Springs, CO?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Colorado Springs?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Colorado Springs.

Paid clinical trials near Colorado Springs

Other metros within reach

Aurora, CO1,566 Denver, CO1,600 Lakewood, CO1,600 Thornton, CO1,602 Greeley, CO156 Fort Collins, CO154 Grand Junction, CO52 Albuquerque, NM344

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Colorado Springs Bladder Issues Due To Spinal Cord Injury in Colorado Springs All conditions

More of CO

Thornton1,602 Denver1,600 Lakewood1,600 Aurora1,566 Greeley156 Fort Collins154 Grand Junction52

New paid studies open every week

Get an email when a new clinical trial starts recruiting within 30 miles of your ZIP code. No spam — only real studies from the NIH registry.

By subscribing you agree to receive study alert emails. Unsubscribe anytime in one click.

Get free trial alerts