Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only

Home/CO/Colorado Springs

Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Colorado Springs, CO

Studies commonly pay $75 to $4,500 per completed study

207 clinical trials are currently recruiting participants within 30 miles of Colorado Springs. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

207studies recruiting

9+research centers nearby

5condition categories

Live from the NIH registry

Studies recruiting near Colorado Springs right now

Top 25 of 207 recruiting studies, sorted by proximity — each links to its official registry page

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: ECOG-ACRIN Cancer Research Group

See eligibility & contact on ClinicalTrials.gov (NCT03937635)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought

Research Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: AstraZeneca

See eligibility & contact on ClinicalTrials.gov (NCT06129864)

A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis

Ulcerative Colitis Phase 2 Interventional 80 participants sought

Peak Gastroenterology Associates — Colorado Springs, Colorado (4.0 mi) · Sponsor: Boehringer Ingelheim

See eligibility & contact on ClinicalTrials.gov (NCT06636656)

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate Phase 2 Interventional 1,431 participants sought

Peak Gastroenterology Associates — Colorado Springs, Colorado (4.0 mi) · Sponsor: Eli Lilly and Company

See eligibility & contact on ClinicalTrials.gov (NCT07415044)

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer Phase 3 Interventional 600 participants sought

UC Health Oncology Research — Colorado Springs, Colorado (4.0 mi) · Sponsor: Hoffmann-La Roche

See eligibility & contact on ClinicalTrials.gov (NCT06793215)

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma, Stage II Pancreatic Cancer AJCC v8 Phase 3 Interventional 356 participants sought

Rocky Mountain Cancer Centers-Penrose — Colorado Springs, Colorado (4.0 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT06958328)

A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

Neuroblastoma Recurrent Phase 2 Interventional 54 participants sought

Children's Hospital of Colorado — Colorado Springs, Colorado (4.0 mi) · Sponsor: St. Jude Children's Research Hospital

See eligibility & contact on ClinicalTrials.gov (NCT07085338)

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 189 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: ECOG-ACRIN Cancer Research Group

See eligibility & contact on ClinicalTrials.gov (NCT02734537)

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Malignancy N/A Observational 240 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: Alliance for Clinical Trials in Oncology

See eligibility & contact on ClinicalTrials.gov (NCT04242095)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: SWOG Cancer Research Network

See eligibility & contact on ClinicalTrials.gov (NCT05561387)

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Primary Open Angle Glaucoma Phase 3 Interventional 130 participants sought

Colorado Eye Institute /ID# 277072 — Colorado Springs, Colorado (4.0 mi) · Sponsor: AbbVie

See eligibility & contact on ClinicalTrials.gov (NCT06822738)

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma Phase 3 Interventional 255 participants sought

UCHealth Memorial Hospital Central — Colorado Springs, Colorado (4.0 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT07198074)

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Arrhythmia, Bradycardia N/A Observational 20,000 participants sought

Research site — Colorado Springs, Colorado (4.0 mi) · Sponsor: Medtronic

See eligibility & contact on ClinicalTrials.gov (NCT00271180)

Improving Care for Rural Patients With Solid Tumors

Lung Cancer, Head and Neck Cancer N/A Interventional 320 participants sought

Memorial Hospital Central — Colorado Springs, Colorado (4.0 mi) · Sponsor: University of Colorado, Denver

See eligibility & contact on ClinicalTrials.gov (NCT04916990)

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

Non-Small Cell Lung Cancer, NSCLC, KRAS, NRAS, HRAS-mutated NSCLC Phase 1, Phase 2 Interventional 616 participants sought

Colorado Health Medical Group - Medical Oncology & Hematology — Colorado Springs, Colorado (4.0 mi) · Sponsor: Revolution Medicines, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06162221)

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

Locally Advanced Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8 Phase 3 Interventional 474 participants sought

Rocky Mountain Cancer Centers-Penrose — Colorado Springs, Colorado (4.0 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT05624996)

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

Metabolic Dysfunction Associated Steatohepatitis Phase 3 Interventional 1,590 participants sought

Future Innovative Treatments — Colorado Springs, Colorado (4.0 mi) · Sponsor: Boehringer Ingelheim

See eligibility & contact on ClinicalTrials.gov (NCT06632457)

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

Miscellaneous Neoplasm, Nos, Non-Neoplastic Condition, Nos N/A Interventional 535 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: Alliance for Clinical Trials in Oncology

See eligibility & contact on ClinicalTrials.gov (NCT07091617)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,209 participants sought

Rocky Mountain Cancer Centers-Penrose — Colorado Springs, Colorado (4.0 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT05946213)

VTP-1000 in Adults With Celiac Disease

Celiac Disease EARLY/Phase 1 Interventional 45 participants sought

Peak Gastroenterology Associates — Colorado Springs, Colorado (4.0 mi) · Sponsor: Barinthus Biotherapeutics

See eligibility & contact on ClinicalTrials.gov (NCT06310291)

A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

Idiopathic Hypersomnia Phase 3 Interventional 248 participants sought

Delta Waves LLC — Colorado Springs, Colorado (4.0 mi) · Sponsor: Harmony Biosciences Management, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT07500090)

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

Geographic Atrophy, Macular Degeneration N/A Observational 500 participants sought

Retina Consultants of Southern Colorado — Colorado Springs, Colorado (4.0 mi) · Sponsor: Astellas Pharma Global Development, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06779773)

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Moderately to Severely Active Crohns Disease Phase 3 Interventional 425 participants sought

Peak Gastroenterology Associates — Colorado Springs, Colorado (4.0 mi) · Sponsor: Hoffmann-La Roche

See eligibility & contact on ClinicalTrials.gov (NCT06819891)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT01810913)

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis Phase 3 Interventional 1,350 participants sought

89bio Clinical Study Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: 89bio, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06318169)

Actively enrolling

Studies you may be able to join near Colorado Springs

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Google-rated

Top-rated research centers in Colorado Springs

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Legacy Clinical Trials of Colorado Springs

★ 5.0

2960 N Circle Dr #125, Colorado Springs, CO 80909

(719) 387-7572

Website

Skylight Health Research

★ 5.0

3100 N Academy Blvd Ste 115, Colorado Springs, CO 80917

(719) 301-7162

Website

"I did the COVID study, the staff is awesome! All very nice and professional."

— IShii Graphics and Media, 5★

MCB Clinical Research Centers

★ 4.1

110 S Parkside Dr, Colorado Springs, CO 80910

(719) 634-6576

Website

"I’ve been coming to this clinical research center for years, and the improvement is honestly impressive. Compared to 4/5 years ago, the facility is n…"

— Holly M, 5★

Optum - Clinical Research

6340 Barnes Rd, Colorado Springs, CO 80922

(844) 761-9865

Website

Lane Center for Academic Health Sciences at UCCS

★ 4.5

4863 N Nevada Ave, Colorado Springs, CO 80918

"Super friendly and helpful staff."

— Michael Nicewonger, 5★

Lynn Institute of the Rockies

★ 5.0

2855 Dublin Blvd, Colorado Springs, CO 80918

(719) 636-3784

Website

"Friendly staff! It's been a pleasure being part of the trials with this group."

— Jacqueline Hjelm, 5★

Ascend Clinical

★ 5.0

9925 Federal Dr, Colorado Springs, CO 80921

(719) 538-1462

WellLife Medical Centers

★ 4.3

975 Garden of the Gods Rd, Colorado Springs, CO 80907

(719) 694-8782

Website

Delta Waves

★ 4.2

5835 Lehman Dr #101, Colorado Springs, CO 80918

(719) 262-9283

Website

"They were amazing. On our road trip, we had to make an unplanned stop here for a piece of medical equipment that I needed. I highly recommend them!"

— Dawn Gordon, 5★

Clinical trials in Colorado Springs: what's recruiting

The Colorado Springs area currently has 207 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Colorado Springs, the most active research areas are:

Cancer & Oncology14 studies
Immune & Skin3 studies
Diabetes & Metabolism2 studies
Liver & Kidney2 studies
Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from Colorado Springs, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Colorado Springs

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Colorado Springs participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Colorado Springs pay?

Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.

Are clinical trials in Colorado Springs safe?

Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.

How do I join a study in Colorado Springs, CO?

Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.

Is compensation for clinical trials taxable?

In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.

How often do new paid studies open in Colorado Springs?

Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Colorado Springs.

Paid clinical trials near Colorado Springs

Other metros within reach

Aurora, CO1,561 Denver, CO1,594 Lakewood, CO1,594 Thornton, CO1,597 Greeley, CO161 Fort Collins, CO159 Grand Junction, CO54 Albuquerque, NM345

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Colorado Springs Bladder Issues Due To Spinal Cord Injury in Colorado Springs All conditions

More of CO

Thornton1,597 Denver1,594 Lakewood1,594 Aurora1,561 Greeley161 Fort Collins159 Grand Junction54

New paid studies open every week

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