Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/OR/Portland
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Portland, OR

Studies commonly pay $75 to $4,500 per completed study

1,027 clinical trials are currently recruiting participants within 30 miles of Portland. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,027studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Portland right now

Top 25 of 1,027 recruiting studies, sorted by proximity — each links to its official registry page

Support Via Technology: Living and Learning With Advancing Dementia-REVISED

Caregiver Burden N/A Interventional 238 participants sought
Oregon Health & Science University, Layton Aging and Alzheimer's Disease Research Center — Portland, Oregon (1.6 mi) · Sponsor: Oregon Health and Science University
See eligibility & contact on ClinicalTrials.gov (NCT06460012)

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Phase 2 Interventional 120 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06465329)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
Providence Portland Medical Center ( Site 0120) — Portland, Oregon (1.6 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults

Acute Respiratory Failure N/A Observational 2,092 participants sought
Oregon Health and Sciences University — Portland, Oregon (1.6 mi) · Sponsor: Brian Driver
See eligibility & contact on ClinicalTrials.gov (NCT06934876)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Oregon Health & Science University, Knight Cancer Institute — Portland, Oregon (1.6 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought
EyeHealth Northwest — Portland, Oregon (1.6 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07553429)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Portland, Oregon (1.6 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device Exemption] Study)

Carotid Artery Calcification, Carotid Artery Diseases N/A Interventional 185 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: Shockwave Medical, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07062471)

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

Urothelial Cancer, Bladder Cancer Phase 2, Phase 3 Interventional 630 participants sought
Research Site — Portland, Oregon (1.6 mi) · Sponsor: Daiichi Sankyo
See eligibility & contact on ClinicalTrials.gov (NCT07129993)

Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease N/A Observational 3,000 participants sought
Oregon Clinic — Portland, Oregon (1.6 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT01915511)

Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up

Asthma, Pulmonary Function N/A Observational 225 participants sought
Oregon Health and Science University (OHSU) — Portland, Oregon (1.6 mi) · Sponsor: Oregon Health and Science University
See eligibility & contact on ClinicalTrials.gov (NCT06106646)

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Non-Small Cell Lung Cancer Phase 3 Interventional 675 participants sought
Research Site — Portland, Oregon (1.6 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06357533)

Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

Complex Cardiovascular Surgery With Cardiopulmonary Bypass Phase 3 Interventional 200 participants sought
Oregon Health & Sciences University — Portland, Oregon (1.6 mi) · Sponsor: CSL Behring
See eligibility & contact on ClinicalTrials.gov (NCT07094087)

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer

Carcinoma, Non-small-Cell Lung Phase 1 Interventional 126 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: Johnson & Johnson Enterprise Innovation Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06116786)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Portland, Oregon (1.6 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06129864)

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

Pulmonary Invasive Fungal Infections, Pulmonary Invasive Aspergillosis N/A Observational 400 participants sought
Oregon Health and Science University — Portland, Oregon (1.6 mi) · Sponsor: Arkansas Children's Hospital Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT03827694)
Actively enrolling

Studies you may be able to join near Portland

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Portland

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Legacy Research Institute

★ 4.4
1225 NE 2nd Ave, Portland, OR 97232
(503) 413-2491
"Safe place to get help, PES is a little uncomfortable but they get you a bed as fast as they can and the nurses are almost all nice"
— Lukas, 4★

Oregon Medical Research Center

★ 4.4
1750 S Harbor Way Unit 330, Portland, OR 97201
(503) 245-1525
"Fantastic start to finish. The Staff at OMRC were kind, professional, helpful, informative, and were the first healthcare providers to believe me and…"
— Amy Pettinger, 5★

Summit Research Network Oregon, Inc.

★ 4.6
2701 NW Vaughn St #350, Portland, OR 97210
(503) 279-8252
"The entire staff from the front dest to the lab lady's, doctors, and medical assistants are extremely compationate and friendly."
— Valerie Carter, 5★

Kaiser Permanente Center for Health Research

★ 3.4
3800 N Interstate Ave, Portland, OR 97227
(503) 335-2400
"So far, so good! Most professionals seems to be genuinely friendly."
— Luciano De Lopes, 5★

Providence Center for Outcomes Research and Education - Portland

★ 5.0
4400 NE Halsey St Bldg 1, Suite 265, Portland, OR 97213
(503) 215-7170

Earle A. Chiles Research Institute

4805 NE Glisan St Ste 2N35, Portland, OR 97213
(503) 215-6588

Northwest Research Center

★ 5.0
6327 SE Milwaukie Ave, Portland, OR 97202
(503) 238-6233

OHSU Mark O. Hatfield Research Center

★ 3.8
Hatfield Research Center, 3181 SW Sam Jackson Park Rd, Portland, OR 97239
"Doctors, surgeons, faculty, everyone is wonderful & top-of-their-game qualified."
— Robin Knauerhase, 5★

Helfgott Research Institute at NUNM

★ 5.0
2220 SW 1st Ave, Portland, OR 97201
(503) 552-1751
"I came in from one of its sister clinics (Mercy and Wisdom) for a full panel to start a new medication and found the premises pretty open friendly. S…"
— Neko Ramsay, 5★

Clinical trials in Portland: what's recruiting

The Portland area currently has 1,027 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Portland, the most active research areas are:

  • Cancer & Oncology12 studies
  • Lungs & Breathing5 studies
  • Diabetes & Metabolism1 studies
  • Immune & Skin1 studies
  • Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from Portland, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Portland

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Portland participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Portland?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Portland, OR?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Portland?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Portland typically complete one or two studies per year.

Paid clinical trials near Portland

Other metros within reach

Vancouver, WA1,027 Salem, OR116 Olympia, WA234 Eugene, OR149 Tacoma, WA1,465 Bremerton, WA1,486 Seattle, WA1,511 Bellevue, WA1,519

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Portland Bladder Issues Due To Spinal Cord Injury in Portland All conditions

More of OR

Eugene149 Salem116 Medford37

New paid studies open every week

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