Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/OR/Portland
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Portland, OR

Studies commonly pay $75 to $4,500 per completed study

1,021 clinical trials are currently recruiting participants within 30 miles of Portland. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,021studies recruiting
9+research centers nearby
3condition categories
Live from the NIH registry

Studies recruiting near Portland right now

Top 25 of 1,021 recruiting studies, sorted by proximity — each links to its official registry page

Support Via Technology: Living and Learning With Advancing Dementia-REVISED

Caregiver Burden N/A Interventional 238 participants sought
Oregon Health & Science University, Layton Aging and Alzheimer's Disease Research Center — Portland, Oregon (1.6 mi) · Sponsor: Oregon Health and Science University
See eligibility & contact on ClinicalTrials.gov (NCT06460012)

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Phase 2 Interventional 120 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06465329)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Oregon Health & Science University, Knight Cancer Institute — Portland, Oregon (1.6 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device Exemption] Study)

Carotid Artery Calcification, Carotid Artery Diseases N/A Interventional 185 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: Shockwave Medical, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07062471)

Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease N/A Observational 3,000 participants sought
Oregon Clinic — Portland, Oregon (1.6 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT01915511)

Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up

Asthma, Pulmonary Function N/A Observational 225 participants sought
Oregon Health and Science University (OHSU) — Portland, Oregon (1.6 mi) · Sponsor: Oregon Health and Science University
See eligibility & contact on ClinicalTrials.gov (NCT06106646)

A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer

Carcinoma, Non-small-Cell Lung Phase 1 Interventional 126 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: Johnson & Johnson Enterprise Innovation Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06116786)

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

Pulmonary Invasive Fungal Infections, Pulmonary Invasive Aspergillosis N/A Observational 400 participants sought
Oregon Health and Science University — Portland, Oregon (1.6 mi) · Sponsor: Arkansas Children's Hospital Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT03827694)

Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Face and Scalp

Actinic Keratosis Phase 3 Interventional 160 participants sought
Oregon Dermatology and Research Center — Portland, Oregon (1.6 mi) · Sponsor: Sun Pharmaceutical Industries, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07144345)

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma Phase 3 Interventional 1,524 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT07200830)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05561387)

IVIG for Infection Prevention After CAR-T-Cell Therapy

Hematologic Malignancies Phase 2 Interventional 150 participants sought
Oregon Health and Science University (OHSU) Knight Cancer Institute — Portland, Oregon (1.6 mi) · Sponsor: Fred Hutchinson Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT05952804)

Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

Viral Pneumonia Phase 2 Interventional 550 participants sought
Oregon Health & Science University (OHSU) — Portland, Oregon (1.6 mi) · Sponsor: Synairgen Research Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT06999603)

Ruxolitinib With Azacitidine Maintenance for the Treatment of Patients With Acute Myeloid Leukemia Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation

Acute Myeloid Leukemia Phase 1 Interventional 40 participants sought
OHSU Knight Cancer Institute — Portland, Oregon (1.6 mi) · Sponsor: OHSU Knight Cancer Institute
See eligibility & contact on ClinicalTrials.gov (NCT07548983)

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 Phase 3 Interventional 1,875 participants sought
Providence Portland Medical Center — Portland, Oregon (1.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05675410)

Hearing Aids for Veterans With Functional Hearing Difficulties

Auditory Processing Disorder N/A Interventional 142 participants sought
VA Portland Health Care System, Portland, OR — Portland, Oregon (1.6 mi) · Sponsor: VA Office of Research and Development
See eligibility & contact on ClinicalTrials.gov (NCT06117254)

Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

Advanced Solid Tumor, Metastatic Solid Tumor Phase 1 Interventional 220 participants sought
Oregon Health and Science University — Portland, Oregon (1.6 mi) · Sponsor: Circle Pharma
See eligibility & contact on ClinicalTrials.gov (NCT06577987)

Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

IgA Nephropathy Phase 4 Interventional 60 participants sought
Oregon Health & Science University (OHSU) - Nephrology and Hypertension Clinic — Portland, Oregon (1.6 mi) · Sponsor: Calliditas Therapeutics AB
See eligibility & contact on ClinicalTrials.gov (NCT06712407)
Actively enrolling

Studies you may be able to join near Portland

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Portland

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Legacy Research Institute

★ 4.4
1225 NE 2nd Ave, Portland, OR 97232
(503) 413-2491
"Safe place to get help, PES is a little uncomfortable but they get you a bed as fast as they can and the nurses are almost all nice"
— Lukas, 4★

Oregon Medical Research Center

★ 4.4
1750 S Harbor Way Unit 330, Portland, OR 97201
(503) 245-1525
"Fantastic start to finish. The Staff at OMRC were kind, professional, helpful, informative, and were the first healthcare providers to believe me and…"
— Amy Pettinger, 5★

Summit Research Network Oregon, Inc.

★ 4.6
2701 NW Vaughn St #350, Portland, OR 97210
(503) 279-8252
"The entire staff from the front dest to the lab lady's, doctors, and medical assistants are extremely compationate and friendly."
— Valerie Carter, 5★

Kaiser Permanente Center for Health Research

★ 3.4
3800 N Interstate Ave, Portland, OR 97227
(503) 335-2400
"So far, so good! Most professionals seems to be genuinely friendly."
— Luciano De Lopes, 5★

Providence Center for Outcomes Research and Education - Portland

★ 5.0
4400 NE Halsey St Bldg 1, Suite 265, Portland, OR 97213
(503) 215-7170

Earle A. Chiles Research Institute

4805 NE Glisan St Ste 2N35, Portland, OR 97213
(503) 215-6588

Northwest Research Center

★ 5.0
6327 SE Milwaukie Ave, Portland, OR 97202
(503) 238-6233

OHSU Mark O. Hatfield Research Center

★ 3.8
Hatfield Research Center, 3181 SW Sam Jackson Park Rd, Portland, OR 97239
"Doctors, surgeons, faculty, everyone is wonderful & top-of-their-game qualified."
— Robin Knauerhase, 5★

Helfgott Research Institute at NUNM

★ 5.0
2220 SW 1st Ave, Portland, OR 97201
(503) 552-1751
"I came in from one of its sister clinics (Mercy and Wisdom) for a full panel to start a new medication and found the premises pretty open friendly. S…"
— Neko Ramsay, 5★

Clinical trials in Portland: what's recruiting

The Portland area currently has 1,021 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Portland, the most active research areas are:

  • Cancer & Oncology12 studies
  • Lungs & Breathing3 studies
  • Brain & Mental Health1 studies

Every listing shows the study phase, the recruiting site and its distance from Portland, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Portland

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Portland participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Portland?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Portland, OR?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Portland?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Portland typically complete one or two studies per year.

Paid clinical trials near Portland

Other metros within reach

Vancouver, WA1,021 Salem, OR116 Olympia, WA234 Eugene, OR148 Tacoma, WA1,464 Bremerton, WA1,481 Seattle, WA1,510 Bellevue, WA1,520

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Portland Bladder Issues Due To Spinal Cord Injury in Portland All conditions

More of OR

Eugene148 Salem116 Medford36

New paid studies open every week

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