Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/WI/Appleton
Updated October 2026 from ClinicalTrials.gov

Paid Clinical Trials in Appleton, WI

Studies commonly pay $75 to $4,500 per completed study

150 clinical trials are currently recruiting participants within 30 miles of Appleton. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

150studies recruiting
2+research centers nearby
3condition categories
Live from the NIH registry

Studies recruiting near Appleton right now

Top 25 of 150 recruiting studies, sorted by proximity — each links to its official registry page

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought
Vince Lombardi Cancer Clinic - Oshkosh — Oshkosh, Wisconsin (19.1 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04251052)

Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

Lung Non-Small Cell Carcinoma Phase 3 Interventional 336 participants sought
Bellin Memorial Hospital — Green Bay, Wisconsin (24.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07388524)

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma Phase 3 Interventional 364 participants sought
Vince Lombardi Cancer Clinic - Oshkosh — Oshkosh, Wisconsin (19.1 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT04510597)

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

Cigarette Smoking-Related Carcinoma Phase 3 Interventional 600 participants sought
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin (24.7 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05008848)

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Multiple conditions Phase 2 Interventional 120 participants sought
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin (24.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06649812)

Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief

Neck Pain Musculoskeletal, Neck Pain Treatment N/A Interventional 160 participants sought
Emplify by Bellin Health Ashwaubenon — Green Bay, Wisconsin (24.7 mi) · Sponsor: Baylor University
See eligibility & contact on ClinicalTrials.gov (NCT06906107)

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma Phase 3 Interventional 255 participants sought
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin (24.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07198074)

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

High Grade Osteosarcoma, Localized Osteosarcoma Phase 2, Phase 3 Interventional 1,122 participants sought
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin (24.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05691478)

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Classic Follicular Lymphoma, Follicular Lymphoma With Unusual Cytological Features Phase 3 Interventional 600 participants sought
ThedaCare Regional Cancer Center — Appleton, Wisconsin (1.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06337318)

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Heart Failure Phase 3 Interventional 11,300 participants sought
Research Site — Green Bay, Wisconsin (24.7 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06677060)

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

Colorectal Cancer, Sarcopenia N/A Observational 300 participants sought
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin (24.7 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT03998202)

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Phase 3 Interventional 247 participants sought
ThedaCare Regional Cancer Center — Appleton, Wisconsin (1.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04269902)

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

Myelodysplastic Syndrome Phase 2 Interventional 54 participants sought
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin (24.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06577441)

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum N/A Interventional 9,500 participants sought
Ascension Northeast Wisconsin-Saint Elizabeth Cancer Center-Appleton — Appleton, Wisconsin (1.7 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05080673)

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Ganglioneuroblastoma, Ganglioneuroblastoma, Nodular Phase 3 Interventional 750 participants sought
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin (24.7 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT03126916)

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Muscle Invasive Bladder Urothelial Carcinoma, Muscle Invasive Renal Pelvis Urothelial Carcinoma Phase 2, Phase 3 Interventional 992 participants sought
ThedaCare Regional Cancer Center — Appleton, Wisconsin (1.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05987241)

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8 Phase 3 Interventional 306 participants sought
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin (24.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06498635)

The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials

Cancer N/A Interventional 500 participants sought
Vince Lombardi Cancer Clinic - Oshkosh — Oshkosh, Wisconsin (19.1 mi) · Sponsor: Eastern Cooperative Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT06756607)

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 335 participants sought
ThedaCare Regional Cancer Center — Appleton, Wisconsin (1.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05554406)

Standardized Application of Feeding Evaluations Using SMART Tool

Infant and Young Child Feeding N/A Interventional 3,500 participants sought
Aurora Medical Center Oshkosh — Oshkosh, Wisconsin (19.1 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT07136610)

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Intracranial Meningioma, Recurrent Meningioma Phase 2 Interventional 124 participants sought
Vince Lombardi Cancer Clinic - Oshkosh — Oshkosh, Wisconsin (19.1 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT02523014)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin (24.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT01810913)
Actively enrolling

Studies you may be able to join near Appleton

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Appleton

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

ThedaCare Regional Medical Center-Appleton

★ 3.1
1818 N Meade St, Appleton, WI 54911
(920) 731-4101

NeuroSpine Center Of Wisconsin

★ 4.8
5320 W Michaels Dr, Appleton, WI 54913
(920) 882-8200

Clinical trials in Appleton: what's recruiting

The Appleton area currently has 150 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Appleton, the most active research areas are:

  • Cancer & Oncology18 studies
  • Liver & Kidney2 studies
  • Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from Appleton, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Appleton

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Appleton participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Appleton pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
How do I join a study in Appleton, WI?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Appleton?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Appleton.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Appleton typically complete one or two studies per year.

Paid clinical trials near Appleton

Other metros within reach

Green Bay, WI147 Milwaukee, WI706 Madison, WI526 Round Lake Beach, IL469 Rockford, IL112 Muskegon, MI64 Aurora, IL615 Chicago, IL2,443

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Appleton Bladder Issues Due To Spinal Cord Injury in Appleton All conditions

More of WI

Milwaukee706 Madison526 Green Bay147

New paid studies open every week

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