Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/AL/Birmingham
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Birmingham, AL

Studies commonly pay $75 to $4,500 per completed study

962 clinical trials are currently recruiting participants within 30 miles of Birmingham. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

962studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Birmingham right now

Top 25 of 962 recruiting studies, sorted by proximity — each links to its official registry page

Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients

Amyotrophic Lateral Sclerosis Phase 3 Interventional 495 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: AB Science
See eligibility & contact on ClinicalTrials.gov (NCT03127267)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Children's Hospital of Alabama — Birmingham, Alabama (0.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Study to Investigate the Safety and Efficacy of MEDI0618 Compared to Placebo in Adult Participants With Episodic Migraine

Migraine Phase 2 Interventional 488 participants sought
Flourish - Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06602479)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Veterans Administration Medical Center - Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma Phase 1, Phase 2 Interventional 260 participants sought
UAB Comprehensive Cancer Center — Birmingham, Alabama (0.6 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT05372354)

APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women

Overactive Bladder (OAB), Urinary Urgency N/A Interventional 596 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: Medstar Health Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT06797245)

Multi-Center Clean Air Randomized Controlled Trial in COPD

Chronic Obstructive Pulmonary Disease (COPD) Phase 3 Interventional 770 participants sought
University of Alabama, Lung Health Center — Birmingham, Alabama (0.6 mi) · Sponsor: JHSPH Center for Clinical Trials
See eligibility & contact on ClinicalTrials.gov (NCT06376994)

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes N/A Observational 200 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: Jaeb Center for Health Research
See eligibility & contact on ClinicalTrials.gov (NCT06837181)

Bony Overlap Following Use of the Inferior Border Saw for the 'Low and Short' Sagittal Split: A Split-Mouth Study

Mandibular Surgery N/A Interventional 40 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: University of Alabama at Birmingham
See eligibility & contact on ClinicalTrials.gov (NCT07104656)

A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors

MTAP-deleted Solid Tumors Phase 1, Phase 2 Interventional 450 participants sought
UAB O'Neal Comprehensive Cancer Center - The Kirklin Clinic of UAB Hospital — Birmingham, Alabama (0.6 mi) · Sponsor: Bayer
See eligibility & contact on ClinicalTrials.gov (NCT06914128)

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

Bladder Carcinoma, Ureter Carcinoma N/A Observational 2,020 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: Guardant Health, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05059444)

Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

IgA Nephropathy Phase 4 Interventional 60 participants sought
Univ of Alabama/Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: Calliditas Therapeutics AB
See eligibility & contact on ClinicalTrials.gov (NCT06712407)

UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy

Alzheimer Disease Phase 2 Interventional 160 participants sought
University of Alabama at Birmingham Medical Center — Birmingham, Alabama (0.6 mi) · Sponsor: University of Alabama at Birmingham
See eligibility & contact on ClinicalTrials.gov (NCT03503331)

Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)

Locally Advanced Cervical Cancer Phase 3 Interventional 800 participants sought
Research Site — Birmingham, Alabama (0.6 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06079671)

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Percutaneous Coronary Intervention, Peripheral Endovascular Intervention Phase 4 Interventional 6,000 participants sought
Cardiology, PC — Birmingham, Alabama (0.6 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT06909565)

A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

Acute HIV Infection Phase 2 Interventional 48 participants sought
31788, Alabama CRS — Birmingham, Alabama (0.6 mi) · Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
See eligibility & contact on ClinicalTrials.gov (NCT05719441)

Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

Preterm Delivery, Obstetrical Complications Phase 3 Interventional 1,800 participants sought
University of Alabama - Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: The George Washington University Biostatistics Center
See eligibility & contact on ClinicalTrials.gov (NCT06980025)
Actively enrolling

Studies you may be able to join near Birmingham

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Birmingham

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

UAB St. Vincent's Clinical Research

800 St Vincents Dr #510, Birmingham, AL 35205
(205) 212-6031

Flourish Research - Birmingham

★ 5.0
2660 10th Ave S Ste 735, Building 1, Birmingham, AL 35205
(205) 208-9244

Rehabilitation Research Resource to Enhance Clinical Trials

1720 2nd Ave S, Birmingham, AL 35294
(205) 996-6086

Central Alabama Research

★ 5.0
10 Old Montgomery Hwy #100, Homewood, AL 35209
(205) 949-1907

Alabama Vaccine Research Clinic at UAB

Community Care Bldg, 908 20th St S #310, Birmingham, AL 35294
(205) 975-2839

Clinical Research Consultants

2006 Brookwood Medical Center Dr, Birmingham, AL 35209
(205) 414-9902

O'Neal Cancer Center at UAB

★ 3.2 (28 reviews)
1824 6th Ave S, Birmingham, AL 35233
(205) 801-9034
"The hematology department specifically NP Kathryn Mercer is very dismissive has wasted my time! Wouldn't advise anyone to go see her and go somewhere…"
— Liah C, 1★

Accel Research Sites Network - Birmingham

★ 4.5
2017 Canyon Rd #41, Vestavia Hills, AL 35216
(205) 757-8301
"I enjoyed participating in this research project. Everyone was courteous and professional."
— Fred hawkins, 5★

Wallace Tumor Institute

★ 4.3 (4 reviews)
1824 6th Ave S, Birmingham, AL 35233
(205) 934-4011
"Very clean and the workers are all very nice and helpful. I was able to feel safe and find my MRI/PET on basement floor no problem after asking a few…"
— Heartbeatviews, 5★

Clinical trials in Birmingham: what's recruiting

The Birmingham area currently has 962 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Birmingham, the most active research areas are:

  • Cancer & Oncology8 studies
  • Liver & Kidney3 studies
  • Diabetes & Metabolism2 studies
  • Heart & Vascular2 studies
  • Lungs & Breathing1 studies

Every listing shows the study phase, the recruiting site and its distance from Birmingham, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Birmingham

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Birmingham participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Birmingham pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Birmingham safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Birmingham, AL?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
How often do new paid studies open in Birmingham?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Birmingham.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Birmingham typically complete one or two studies per year.

Paid clinical trials near Birmingham

Other metros within reach

Tuscaloosa, AL23 Huntsville, AL89 Montgomery, AL14 Columbus, GA67 Chattanooga, TN150 Murfreesboro, TN79 Atlanta, GA1,693 Nashville, TN1,347

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Birmingham Chronic Kidney Disease (HealthMatch) in Birmingham Bladder Issues Due To Spinal Cord Injury in Birmingham All conditions

More of AL

Mobile168 Huntsville89 Tuscaloosa23 Montgomery14

New paid studies open every week

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