Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/AL/Birmingham
Updated October 2026 from ClinicalTrials.gov

Paid Clinical Trials in Birmingham, AL

Studies commonly pay $75 to $4,500 per completed study

975 clinical trials are currently recruiting participants within 30 miles of Birmingham. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

975studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Birmingham right now

Top 25 of 975 recruiting studies, sorted by proximity — each links to its official registry page

Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients

Amyotrophic Lateral Sclerosis Phase 3 Interventional 495 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: AB Science
See eligibility & contact on ClinicalTrials.gov (NCT03127267)

Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

Generalized Myasthenia Gravis N/A Observational 500 participants sought
Clinical Trial Site — Birmingham, Alabama (0.6 mi) · Sponsor: Alexion Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04202341)

ViTAA Registry Pre- and Post-Operative Monitoring for Endovascular Aortic Aneurysm Repair and Serial Monitoring for AAA

Abdominal Aortic Aneurysms N/A Observational 200 participants sought
UAB - University of Alabama in Birmingham Hospital — Birmingham, Alabama (0.6 mi) · Sponsor: ViTAA Medical Solutions
See eligibility & contact on ClinicalTrials.gov (NCT05004051)

Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

Hematuria - Cause Not Known N/A Interventional 1,000 participants sought
Urology Centers of Alabama — Homewood, Alabama (3.9 mi) · Sponsor: Pacific Edge Limited
See eligibility & contact on ClinicalTrials.gov (NCT06394869)

Providing an Optimized and Empowered Pregnancy for You (POPPY) Aim 3: Randomized Controlled Trial

Pregnancy Complications, Maternal Distress N/A Interventional 400 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: University of Alabama at Birmingham
See eligibility & contact on ClinicalTrials.gov (NCT06510075)

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

Ovarian Cancer, Fallopian Tube Cancer Phase 2 Interventional 270 participants sought
004 — Birmingham, Alabama (0.6 mi) · Sponsor: Corcept Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06906341)

Evaluating an Interactive Digital Toolkit for Women's PrEP Implementation

HIV Prevention, HIV Risk N/A Interventional 125 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: University of Alabama at Birmingham
See eligibility & contact on ClinicalTrials.gov (NCT07292584)

High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants

Extreme Prematurity, Enteral Nutrition Phase 1, Phase 2 Interventional 150 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: University of Alabama at Birmingham
See eligibility & contact on ClinicalTrials.gov (NCT07307612)

Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma

NK-Cell Lymphoma, NK-Cell Leukemia EARLY/Phase 1 Interventional 40 participants sought
University of Alabama — Birmingham, Alabama (0.6 mi) · Sponsor: New York Medical College
See eligibility & contact on ClinicalTrials.gov (NCT03719105)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Veterans Administration Medical Center - Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Advanced or Metastatic Colorectal Cancer Phase 1, Phase 2 Interventional 225 participants sought
O Neal Comprehensive Cancer Center at UAB — Birmingham, Alabama (0.6 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT05379595)

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes N/A Observational 200 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: Jaeb Center for Health Research
See eligibility & contact on ClinicalTrials.gov (NCT06837181)

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

Prostate Cancer Phase 3 Interventional 940 participants sought
Urology Centers Of Alabama Pc — Homewood, Alabama (3.9 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06855277)

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

NSCLC (Non-small Cell Lung Cancer), Non-Small Cell Lung Cancer Phase 3 Interventional 590 participants sought
Alabama Oncology — Birmingham, Alabama (0.6 mi) · Sponsor: Revolution Medicines, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06881784)

WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis Phase 2 Interventional 164 participants sought
WISPer Site in Birmingham, AL — Birmingham, Alabama (0.6 mi) · Sponsor: Mediar Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06967805)

A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors

Advanced Solid Tumor Phase 1 Interventional 105 participants sought
University of Alabama At Birmingham Hospital — Birmingham, Alabama (0.6 mi) · Sponsor: BeOne Medicines
See eligibility & contact on ClinicalTrials.gov (NCT07226349)

A Study of Buntanetap in Participants With PD

Parkinson's Disease (PD), Deep Brain Stimulation Phase 2, Phase 3 Interventional 500 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: Annovis Bio Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07284784)

COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

Complex Congenital Heart Defect, Dysfunctional RVOT Conduit N/A Interventional 108 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: Edwards Lifesciences
See eligibility & contact on ClinicalTrials.gov (NCT02744677)

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

Parkinson Disease N/A Observational 4,500 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: Michael J. Fox Foundation for Parkinson's Research
See eligibility & contact on ClinicalTrials.gov (NCT04477785)

Diet Interventions: Remitted and Evaluated as Complementary Treatments for Pain

Knee Osteoarthritis N/A Interventional 200 participants sought
University of Alabama at Birmingham — Birmingham, Alabama (0.6 mi) · Sponsor: University of Alabama at Birmingham
See eligibility & contact on ClinicalTrials.gov (NCT05785884)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Birmingham, Alabama (0.6 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06129864)

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

Relapsing Multiple Sclerosis, Multiple Sclerosis N/A Observational 2,000 participants sought
TG Therapeutics Investigational Trial Site — Birmingham, Alabama (0.6 mi) · Sponsor: TG Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06433752)
Actively enrolling

Studies you may be able to join near Birmingham

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Birmingham

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

UAB St. Vincent's Clinical Research

800 St Vincents Dr #510, Birmingham, AL 35205
(205) 212-6031

Flourish Research - Birmingham

★ 5.0
2660 10th Ave S Ste 735, Building 1, Birmingham, AL 35205
(205) 208-9244

Rehabilitation Research Resource to Enhance Clinical Trials

1720 2nd Ave S, Birmingham, AL 35294
(205) 996-6086

Central Alabama Research

★ 5.0
10 Old Montgomery Hwy #100, Homewood, AL 35209
(205) 949-1907

Alabama Vaccine Research Clinic at UAB

Community Care Bldg, 908 20th St S #310, Birmingham, AL 35294
(205) 975-2839

Clinical Research Consultants

2006 Brookwood Medical Center Dr, Birmingham, AL 35209
(205) 414-9902

O'Neal Cancer Center at UAB

★ 3.2 (28 reviews)
1824 6th Ave S, Birmingham, AL 35233
(205) 801-9034
"The hematology department specifically NP Kathryn Mercer is very dismissive has wasted my time! Wouldn't advise anyone to go see her and go somewhere…"
— Liah C, 1★

Accel Research Sites Network - Birmingham

★ 4.5
2017 Canyon Rd #41, Vestavia Hills, AL 35216
(205) 757-8301
"I enjoyed participating in this research project. Everyone was courteous and professional."
— Fred hawkins, 5★

Wallace Tumor Institute

★ 4.3 (4 reviews)
1824 6th Ave S, Birmingham, AL 35233
(205) 934-4011
"Very clean and the workers are all very nice and helpful. I was able to feel safe and find my MRI/PET on basement floor no problem after asking a few…"
— Heartbeatviews, 5★

Clinical trials in Birmingham: what's recruiting

The Birmingham area currently has 975 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Birmingham, the most active research areas are:

  • Cancer & Oncology8 studies
  • Lungs & Breathing3 studies
  • Brain & Mental Health3 studies
  • Heart & Vascular2 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Birmingham, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Birmingham

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Birmingham participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Birmingham pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Birmingham safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Birmingham, AL?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
How often do new paid studies open in Birmingham?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Birmingham.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Birmingham typically complete one or two studies per year.

Paid clinical trials near Birmingham

Other metros within reach

Tuscaloosa, AL23 Huntsville, AL93 Montgomery, AL14 Columbus, GA68 Chattanooga, TN138 Murfreesboro, TN80 Atlanta, GA1,713 Nashville, TN1,334

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Birmingham Chronic Kidney Disease (HealthMatch) in Birmingham Bladder Issues Due To Spinal Cord Injury in Birmingham All conditions

More of AL

Mobile176 Huntsville93 Tuscaloosa23 Montgomery14

New paid studies open every week

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