Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TN/Chattanooga
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Chattanooga, TN

Studies commonly pay $75 to $4,500 per completed study

146 clinical trials are currently recruiting participants within 30 miles of Chattanooga. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

146studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Chattanooga right now

Top 25 of 146 recruiting studies, sorted by proximity — each links to its official registry page

A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions.

Ankle Arthrodesis or Arthroplasty, Hindfoot Fusion N/A Interventional 126 participants sought
Integrity Orthopedics and Sports Medicine — Chattanooga, Tennessee (3.8 mi) · Sponsor: Kuros Biosurgery AG

Comparison of Epi-ON Corneal Collagen Crosslinking Performed Using an 18-Minute UVA Exposure vs. a 24-Minute UVA Exposure on Eyes With Ectatic Corneal Diseases

Keratoconus, Ectasia of Cornea Phase 3 Interventional 485 participants sought
Woolfson Eye Institute — Chattanooga, Tennessee (3.8 mi) · Sponsor: Woolfson Eye Institute

A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

Type 1 Diabetes Mellitus With Hypoglycemia Phase 2 Interventional 186 participants sought
University Diabetes & Endocrine Consultants — Chattanooga, Tennessee (3.8 mi) · Sponsor: Zucara Therapeutics Inc.

A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)

Recurrent or Metastatic Solid Tumors Phase 2 Interventional 520 participants sought
Tn Gynecologic Oncology Group, Llc — Chattanooga, Tennessee (3.8 mi) · Sponsor: Daiichi Sankyo

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis Phase 2 Interventional 168 participants sought
Nephrology & Hypertension Specialists — Dalton, Georgia (25.8 mi) · Sponsor: R1 Therapeutics

Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome

Down Syndrome (DS), Keratoconus Phase 3 Interventional 225 participants sought
Woolfson Eye Institute — Chattanooga, Tennessee (3.8 mi) · Sponsor: Woolfson Eye Institute

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Breast Cancer, Early Breast Cancer Phase 3 Interventional 4,300 participants sought
Research Site — Chattanooga, Tennessee (3.8 mi) · Sponsor: AstraZeneca

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

Endometrial Cancer Phase 3 Interventional 1,123 participants sought
Erlanger Medical Center ( Site 5009) — Chattanooga, Tennessee (3.8 mi) · Sponsor: Merck Sharp & Dohme LLC

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma Phase 2 Interventional 80 participants sought
T C Thompson Children's Hospital — Chattanooga, Tennessee (3.8 mi) · Sponsor: Children's Oncology Group

A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

B-Cell Non-Hodgkins Lymphoma Phase 2 Interventional 100 participants sought
Tennessee Oncology — Chattanooga, Tennessee (3.8 mi) · Sponsor: Hoffmann-La Roche

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

Non-Small Cell Lung Cancer Phase 3 Interventional 860 participants sought
Research Site — Chattanooga, Tennessee (3.8 mi) · Sponsor: AstraZeneca

FastWire REvascularisation of Extremities, (For LOWer Limbs) - FREEFLOW

Chronic Total Occlusion of Artery of the Extremities N/A Interventional 65 participants sought
Vascular Institute of Chattanooga — Chattanooga, Tennessee (3.8 mi) · Sponsor: Versono Medical Ltd

Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Acute Ischemic Stroke, Cerebral Stroke Phase 3 Interventional 514 participants sought
CHI Memorial Neuroscience Institute — Chattanooga, Tennessee (3.8 mi) · Sponsor: Pharmazz, Inc.

RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT

Neoplasms, Arteriovenous Malformation of Central Nervous System N/A Observational 50,000 participants sought
Cyberknife at Erlanger — Chattanooga, Tennessee (3.8 mi) · Sponsor: The Radiosurgery Society

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

Metastatic Breast Cancer Phase 1, Phase 2 Interventional 1,132 participants sought
Tennessee Oncology - Chattanooga Oncology & Hematology Associates — Chattanooga, Tennessee (3.8 mi) · Sponsor: Hoffmann-La Roche

A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH

Non-alcoholic Fatty Liver Disease Phase 3 Interventional 1,200 participants sought
GSK Investigational Site — Chattanooga, Tennessee (3.8 mi) · Sponsor: GlaxoSmithKline

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Intracranial Meningioma, Recurrent Meningioma Phase 2 Interventional 124 participants sought
Memorial Hospital — Chattanooga, Tennessee (3.8 mi) · Sponsor: Alliance for Clinical Trials in Oncology

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Generalized Myasthenia Gravis Phase 3 Interventional 264 participants sought
Erlanger Health, Inc. - 1123255 — Chattanooga, Tennessee (3.8 mi) · Sponsor: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

NASH With Fibrosis, MASH With Fibrosis Phase 3 Interventional 1,650 participants sought
Akero Clinical Study Site — Chattanooga, Tennessee (3.8 mi) · Sponsor: Akero Therapeutics, Inc

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Anaplastic Kidney Wilms Tumor, Recurrent Kidney Wilms Tumor Phase 2 Interventional 256 participants sought
T C Thompson Children's Hospital — Chattanooga, Tennessee (3.8 mi) · Sponsor: Children's Oncology Group
Google-rated

Top-rated research centers in Chattanooga

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

M3 Wake Research Chattanooga

★ 4.5
6035 Shallowford Rd, Chattanooga, TN 37421
(423) 698-4584
"Great friendly staff, get paid for participating in qualified medical research."
— Tyler Yeager, 5★

Nova Research Trials

725 Glenwood Dr Ste 686, Chattanooga, TN 37404
(423) 703-0888

Lynn Institute of Chattanooga

Located in the Missionary Ridge Medical Tower, 725 Glenwood Dr #888, Chattanooga, TN 37404
(423) 713-5966

Chattanooga Research & Medicine

2205 McCallie Ave Ste 301, Chattanooga, TN 37404
(423) 643-2253

Chattanooga Medical Research

★ 5.0
929 Spring Creek Rd, Chattanooga, TN 37412
(423) 648-7794

Wilkins Research Services

★ 4.0
1730 Gunbarrel Rd, Chattanooga, TN 37421
(423) 894-9478
"I had my very first focus group today and I was nervous since I have never done anything like his before. They were extremely sweet, offered us drink…"
— Leila Parker, 5★

Erlanger Endocrinology

★ 2.3
979 E 3rd St Ste A-550, Chattanooga, TN 37403
(423) 778-8224
"Have an appointment today after waiting for 3 months but I haven't been able to get ahold of anyone at the office. They absolutely suck . Please if …"
— sticky mess, 1★

Southeast Clinical Research Center

1102 W Waugh St, Dalton, GA 30720
(706) 913-1779

Scenic City Neurotherapy and Ketamine Center

★ 4.9 (82 reviews)
7405 Shallowford Rd STE 240, Chattanooga, TN 37421
(423) 228-0579
"Exceptional staff across the board. Charles and Brian are incredible providers, Connie, the receptionist is a joy to talk to and be welcomed by every…"
— James Dietzen, 5★

Clinical trials in Chattanooga: what's recruiting

The Chattanooga area currently has 146 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Chattanooga, the most active research areas are:

  • Cancer & Oncology10 studies
  • Liver & Kidney5 studies
  • Heart & Vascular2 studies
  • Diabetes & Metabolism2 studies

Every listing shows the study phase, the recruiting site and its distance from Chattanooga, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Chattanooga

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Chattanooga participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Chattanooga pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Chattanooga?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Chattanooga safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Chattanooga?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.

Paid clinical trials near Chattanooga

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