Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CA/San Francisco
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in San Francisco, CA

Studies commonly pay $75 to $4,500 per completed study

2,236 clinical trials are currently recruiting participants within 30 miles of San Francisco. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

2,236studies recruiting
8+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near San Francisco right now

Top 25 of 2,236 recruiting studies, sorted by proximity — each links to its official registry page

QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

HER2-positive Metastatic Breast Cancer N/A Observational 200 participants sought
University of California San Francisco Medical Center — San Francisco, California (1.9 mi) · Sponsor: Abramson Cancer Center at Penn Medicine
See eligibility & contact on ClinicalTrials.gov (NCT06551116)

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

Niemann-Pick Type C Disease, GM1 Gangliosidosis Phase 3 Interventional 147 participants sought
UCSF Children's Hospital and Research Center at Oakland — Oakland, California (10.1 mi) · Sponsor: Azafaros B.V.
See eligibility & contact on ClinicalTrials.gov (NCT07054515)

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

Melanoma Stage III, Melanoma Stage IV Phase 2 Interventional 25 participants sought
University of California, San Francisco — San Francisco, California (1.9 mi) · Sponsor: University of California, San Francisco
See eligibility & contact on ClinicalTrials.gov (NCT04598009)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
UCSF Medical Center-Mission Bay — San Francisco, California (1.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures

Osteoporotic Fractures, Osteoporosis N/A Observational 648 participants sought
University of California San Francisco (USCF) Department of Orthopaedic Surgery — San Francisco, California (1.9 mi) · Sponsor: AO Foundation, AO Spine
See eligibility & contact on ClinicalTrials.gov (NCT07027306)

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
University of California San Francisco UCSF The Madison Clinic for Pediatric Diabetes — San Francisco, California (1.9 mi) · Sponsor: Medtronic MiniMed, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07228117)

Feasibility of Acquiring Hyperpolarized Imaging in Patients With Meningioma

Meningioma Phase 1 Interventional 50 participants sought
University of California, San Francisco — San Francisco, California (1.9 mi) · Sponsor: Javier Villaneuva-Meyer, MD
See eligibility & contact on ClinicalTrials.gov (NCT06014905)

TBI Rehabilitation and Activation in Veterans

Traumatic Brain Injury N/A Interventional 120 participants sought
San Francisco VA Health Care System — San Francisco, California (1.9 mi) · Sponsor: Northern California Institute of Research and Education
See eligibility & contact on ClinicalTrials.gov (NCT06562127)

APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women

Overactive Bladder (OAB), Urinary Urgency N/A Interventional 596 participants sought
Stanford University — Palo Alto, California (27.3 mi) · Sponsor: Medstar Health Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT06797245)

Implementing Scalable, PAtient-centered, Team-based, Technology-enabled Care for Adults With Type 2 Diabetes (iPATH)

Diabetes Mellitus, Type 2 N/A Interventional 119,680 participants sought
Board of Trustees of the Leland Stanford Junior University — Stanford, California (27.5 mi) · Sponsor: Stanford University
See eligibility & contact on ClinicalTrials.gov (NCT06251323)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — San Francisco, California (1.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

Exploring Clinical Utility of Wearables for the Bladder in Pelvic Health Physical Therapy Clinics

Postpartum Bladder Dysfunction, Post-prostatectomy Bladder Dysfunction N/A Observational 25 participants sought
University of California San Francisco Weill Institute for Neurosciences — San Francisco, California (1.9 mi) · Sponsor: University of California, San Francisco
See eligibility & contact on ClinicalTrials.gov (NCT07451106)

Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)

Help-Seeking Behavior, Pre-exposure Prophylaxis Use N/A Interventional 360 participants sought
San Francisco State University — San Francisco, California (1.9 mi) · Sponsor: San Francisco State University
See eligibility & contact on ClinicalTrials.gov (NCT07475702)

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Carcinoma, Non-Small-Cell Lung Phase 1, Phase 2 Interventional 450 participants sought
UCSF Medical Center at Mission Bay ( Site 0007) — San Francisco, California (1.9 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT04165070)

Automated Insulin for Management of Intrapartum Glycemia

Type 1 Diabetes (T1D), Pregnancy N/A Interventional 150 participants sought
University of California, San Francisco — San Francisco, California (1.9 mi) · Sponsor: University of California, San Francisco
See eligibility & contact on ClinicalTrials.gov (NCT06883344)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
University of California San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center — San Francisco, California (1.9 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

Feasibility of HPV Testing With Mail-delivered Sample Collection Kits

HPV Infection, HIV Infections N/A Observational 135 participants sought
University of California, San Francisco — San Francisco, California (1.9 mi) · Sponsor: University of California, San Francisco
See eligibility & contact on ClinicalTrials.gov (NCT07087145)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
California Pacific Medical Center-Pacific Campus — San Francisco, California (1.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes N/A Observational 200 participants sought
Stanford University — Palo Alto, California (27.3 mi) · Sponsor: Jaeb Center for Health Research
See eligibility & contact on ClinicalTrials.gov (NCT06837181)

Natural History of Medullary Thyroid Cancer to Inform Advanced Disease Management

Advanced Thyroid Gland Medullary Carcinoma, Stage III Thyroid Gland Medullary Carcinoma AJCC v8 N/A Observational 2,030 participants sought
University of California San Francisco — San Francisco, California (1.9 mi) · Sponsor: M.D. Anderson Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT04216732)
Actively enrolling

Studies you may be able to join near San Francisco

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in San Francisco

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

California Pacific Medical Center Research Institute: Sutter Health Affiliate

★ 3.5
475 Brannan St #130, San Francisco, CA 94107
(415) 600-1600

SF Research Institute Inc.

★ 3.2
2566 Ocean Ave, San Francisco, CA 94132
(415) 745-4340

Center For Clinical Research

★ 5.0
2299 Post St Ste 210, San Francisco, CA 94115
(800) 363-1069
"These people are very friendly and experienced from top to bottom."
— Greg Rodriguez, 5★

Power Clinical Trials

461 2ND ST SAN FRANCISCO C131, San Francisco, CA 94107
(415) 900-4227

Quest Clinical Research

★ 5.0
2300 Sutter St #202, San Francisco, CA 94115
(415) 353-0800
"Quest is an amazing medical research company that has offered cutting edge investigational and trial ttherapy to thousands of patients with HIV and h…"
— Karl Eriksen, 5★

SF Infectious Diseases Research Center

2540 23rd St, San Francisco, CA 94110
(415) 806-8554

UCSF Cancer Clinical Trials and Investigational Treatments Center

1825 4th St Fifth Floor, San Francisco, CA 94158
(415) 885-7796

CPMC Research Institute

★ 5.0
2330 Clay St, San Francisco, CA 94115
(415) 561-1785

Clinical trials in San Francisco: what's recruiting

The San Francisco area currently has 2,236 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to San Francisco, the most active research areas are:

  • Cancer & Oncology10 studies
  • Diabetes & Metabolism5 studies
  • Liver & Kidney1 studies
  • Immune & Skin1 studies
  • Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from San Francisco, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in San Francisco

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

San Francisco participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in San Francisco?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in San Francisco safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in San Francisco, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in San Francisco?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of San Francisco.

Paid clinical trials near San Francisco

Other metros within reach

Oakland, CA2,257 Hayward, CA2,266 Vallejo, CA1,505 Concord, CA1,513 Fremont, CA2,254 Sunnyvale, CA1,165 Fairfield, CA348 Antioch, CA449

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in San Francisco Chronic Kidney Disease (HealthMatch) in San Francisco Bladder Issues Due To Spinal Cord Injury in San Francisco All conditions

More of CA

Long Beach3,348 Torrance3,239 Fullerton3,230 Anaheim3,164 Garden Grove3,162 Pomona3,123 Glendale2,948 Los Angeles2,936 Huntington Beach2,847 Santa Clarita2,389 Hayward2,266 Oakland2,257

New paid studies open every week

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