Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/IN/South Bend
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in South Bend, IN

Studies commonly pay $75 to $4,500 per completed study

110 clinical trials are currently recruiting participants within 30 miles of South Bend. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

110studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near South Bend right now

Top 25 of 110 recruiting studies, sorted by proximity — each links to its official registry page

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma, Grade 3b Follicular Lymphoma Phase 2 Interventional 396 participants sought
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: SWOG Cancer Research Network

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma, Stage II Pancreatic Cancer AJCC v8 Phase 3 Interventional 356 participants sought
Goshen Center for Cancer Care — Goshen, Indiana (23.4 mi) · Sponsor: NRG Oncology

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 189 participants sought
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: ECOG-ACRIN Cancer Research Group

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Classic Follicular Lymphoma, Follicular Lymphoma With Unusual Cytological Features Phase 3 Interventional 600 participants sought
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: National Cancer Institute (NCI)

A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)

Focal Segmental Glomerulosclerosis Phase 3 Interventional 286 participants sought
Nephrology Physicians - Mishawaka — Mishawaka, Indiana (5.8 mi) · Sponsor: Boehringer Ingelheim

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Malignancy N/A Observational 240 participants sought
Memorial Hospital of South Bend — South Bend, Indiana (1.1 mi) · Sponsor: Alliance for Clinical Trials in Oncology

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: SWOG Cancer Research Network

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction Phase 3 Interventional 5,056 participants sought
Midwest Cardiovascular Research And Education Foundation — Elkhart, Indiana (15.1 mi) · Sponsor: Amgen

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

Metabolic Dysfunction Associated Steatohepatitis Phase 3 Interventional 1,590 participants sought
Digestive Research Alliance of Michiana — South Bend, Indiana (1.1 mi) · Sponsor: Boehringer Ingelheim

Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome

Respiratory Distress Syndrome, Pre-term Infants Phase 3 Interventional 520 participants sought
Memorial Hospital of South Bend — South Bend, Indiana (1.1 mi) · Sponsor: Aerogen Pharma Limited

Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula

Pancreatic Carcinoma, Pancreatic Neoplasm Phase 3 Interventional 274 participants sought
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: SWOG Cancer Research Network

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma Phase 3 Interventional 255 participants sought
Memorial Hospital of South Bend — South Bend, Indiana (1.1 mi) · Sponsor: National Cancer Institute (NCI)

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity Phase 2 Interventional 338 participants sought
Memorial Hospital of South Bend — South Bend, Indiana (1.1 mi) · Sponsor: OHB Neonatology Ltd.

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,209 participants sought
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: NRG Oncology

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis Phase 3 Interventional 1,350 participants sought
89bio Clinical Study Site — South Bend, Indiana (1.1 mi) · Sponsor: 89bio, Inc.

Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

Resectable Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8 Phase 3 Interventional 1,100 participants sought
Goshen Center for Cancer Care — Goshen, Indiana (23.4 mi) · Sponsor: Alliance for Clinical Trials in Oncology

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought
Memorial Hospital of South Bend — South Bend, Indiana (1.1 mi) · Sponsor: National Cancer Institute (NCI)

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma Phase 2 Interventional 81 participants sought
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: National Cancer Institute (NCI)

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

Colorectal Cancer Stage II, Colorectal Cancer Stage III Phase 3 Interventional 1,057 participants sought
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: SWOG Cancer Research Network

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Heart Failure and Impaired Kidney Function Phase 3 Interventional 4,800 participants sought
Research Site — Elkhart, Indiana (15.1 mi) · Sponsor: AstraZeneca

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Stage I Breast Cancer Phase 3 Interventional 1,670 participants sought
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: NRG Oncology

A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

Areata Alopecia, Alopecia Phase 3 Interventional 595 participants sought
The South Bend Clinic Center for Research — South Bend, Indiana (1.1 mi) · Sponsor: Eli Lilly and Company

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Heart Failure Phase 3 Interventional 4,200 participants sought
Midwest Cardiovascular Research and Education Foundation — Elkhart, Indiana (15.1 mi) · Sponsor: Boehringer Ingelheim
Actively enrolling

Studies you may be able to join near South Bend

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Google-rated

Top-rated research centers in South Bend

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Center for Rare and Neglected Diseases

18885 Moose Krause Cir Galvin Life Sciences Center, Notre Dame, IN 46556
(574) 631-8831

Digestive Research Alliance of Michiana

★ 5.0
53830 Generations Dr Ste 110, South Bend, IN 46635
(574) 393-9755

Notre Dame Clinical Law Center

★ 3.5
725 Howard St, South Bend, IN 46617
(574) 631-7795
"It’s just not all it’s cracked up to be . They may and may not help."
— Glen Smarr, 2★

Velocity Clinical Research

★ 4.5
55 University Dr Ste 106, Valparaiso, IN 46383
(219) 464-8302
"Do go there, 2 minutes to load a card, after you done your part, I say because I'm black."
— Crystal Washington, 1★

Cardinal Recovery

★ 4.7 (365 reviews)
3606 E Jefferson Blvd, South Bend, IN 46615
(574) 406-2739
"Staff is very helpful and seem to genuinely care. Unfortunately the people running the place are the opposite."
— Geoffrey Payne, 3★

Medical Behavioral Hospital of Mishawaka

★ 2.2 (122 reviews)
1625 E Jefferson Blvd, Mishawaka, IN 46545
(574) 255-1400
"Im not very happy about my "made up" diagnosis. I would like it reversed.<br><br>7 days."
— Richard Hemenway, 1★

Physicians HolisticHealth Alliance

★ 4.1 (41 reviews)
53800 Generations Dr, South Bend, IN 46635
(574) 273-3880
"PHA is a hidden gem! I have never met two providers that care so much about their patients wellbeing. The knowledge and care I have received over the…"
— Leigh Parks, 5★

LūM Granger

★ 4.8
7221 N Fir Rd, Granger, IN 46530
(574) 968-5166
"These people are some of the most friendly, caring professionals I’ve encountered. Thank you so much"
— Lisa Harkins, 5★

Chicago Clinical Research Institute, Inc.

★ 5.0
611 W Roosevelt Rd, Chicago, IL 60607
(312) 823-6800

Clinical trials in South Bend: what's recruiting

The South Bend area currently has 110 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to South Bend, the most active research areas are:

  • Cancer & Oncology13 studies
  • Heart & Vascular3 studies
  • Diabetes & Metabolism3 studies
  • Liver & Kidney3 studies
  • Lungs & Breathing2 studies

Every listing shows the study phase, the recruiting site and its distance from South Bend, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in South Bend

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

South Bend participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in South Bend pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in South Bend safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
What is the difference between a research center and a hospital study in South Bend?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in South Bend?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of South Bend.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in South Bend typically complete one or two studies per year.

Paid clinical trials near South Bend

Other metros within reach

By condition

Eligibility and exclusions, condition by condition

More of IN

New paid studies open every week

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