Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/IN/Indianapolis
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Indianapolis, IN

Studies commonly pay $75 to $4,500 per completed study

915 clinical trials are currently recruiting participants within 30 miles of Indianapolis. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

915studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Indianapolis right now

Top 25 of 915 recruiting studies, sorted by proximity — each links to its official registry page

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A

Von Willebrand Disease, Type 3, Concomitant VWD and Hemophilia Phase 1 Interventional 40 participants sought
Innovative Hematology, Inc. (IHI) — Indianapolis, Indiana (0.9 mi) · Sponsor: Bleeding and Clotting Disorders Institute Peoria, Illinois
See eligibility & contact on ClinicalTrials.gov (NCT05500807)

Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma

Large Cell Lymphoma, Diffuse, Relapsed Cancer Phase 2 Interventional 35 participants sought
Indiana University Melvin and Bren Simon Comprehensive Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: Dipenkumar Modi
See eligibility & contact on ClinicalTrials.gov (NCT05852717)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Riley Hospital for Children — Indianapolis, Indiana (0.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Community Health Network, Inc — Indianapolis, Indiana (0.9 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
Indiana University Health Riley Hospital for Children — Indianapolis, Indiana (0.9 mi) · Sponsor: Medtronic MiniMed, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07228117)

A Study of Buntanetap in Participants With PD

Parkinson's Disease (PD), Deep Brain Stimulation Phase 2, Phase 3 Interventional 500 participants sought
Josephson Wallack Munshower Neurology, P.C. — Indianapolis, Indiana (0.9 mi) · Sponsor: Annovis Bio Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07284784)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Indiana University/Melvin and Bren Simon Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8 Phase 3 Interventional 428 participants sought
Indiana University/Melvin and Bren Simon Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05646316)

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Solid Tumor, Adult, Metastatic Breast Cancer Phase 1 Interventional 392 participants sought
Indiana University Simon Comprehensive Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
See eligibility & contact on ClinicalTrials.gov (NCT06625775)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
Indiana University Melvin and Bren Simon Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma, Relapsed/Refractory Multiple Myeloma Phase 2 Interventional 100 participants sought
Indiana University Health — Indianapolis, Indiana (0.9 mi) · Sponsor: C4 Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07284758)

A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep in Subjects With Neurotrophic Keratitis

Neurotrophic Keratitis Phase 2 Interventional 54 participants sought
Midwest Cornea Associates — Carmel, Indiana (14.0 mi) · Sponsor: TearSolutions, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07568730)

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

Pulmonary Invasive Fungal Infections, Pulmonary Invasive Aspergillosis N/A Observational 400 participants sought
Indiana University School of Medicine — Indianapolis, Indiana (0.9 mi) · Sponsor: Arkansas Children's Hospital Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT03827694)

Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up

Asthma, Pulmonary Function N/A Observational 225 participants sought
Indiana University — Indianapolis, Indiana (0.9 mi) · Sponsor: Oregon Health and Science University
See eligibility & contact on ClinicalTrials.gov (NCT06106646)

rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant Depression

Depression, Treatment Resistant N/A Interventional 20 participants sought
Goodman Hall Neuroscience Center — Indianapolis, Indiana (0.9 mi) · Sponsor: Indiana University
See eligibility & contact on ClinicalTrials.gov (NCT06511544)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Indianapolis, Indiana (0.9 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

Parkinson Disease Phase 2 Interventional 150 participants sought
Josephson Wallack Munshower Neurology PC (Site #231) — Indianapolis, Indiana (0.9 mi) · Sponsor: Appello Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07432958)

Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease

Primary Mitochondrial Disease Phase 2 Interventional 180 participants sought
IU Health University Hospital — Indianapolis, Indiana (0.9 mi) · Sponsor: Pharming Technologies B.V.
See eligibility & contact on ClinicalTrials.gov (NCT05650229)

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Non-Small Cell Lung Cancer Phase 3 Interventional 675 participants sought
Research Site — Noblesville, Indiana (19.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06357533)

Post-Operative Thoracolumosacral Orthosis for PJK

Proximal Junctional Kyphosis, Adult Spinal Deformity Surgery Phase 4 Interventional 84 participants sought
Indiana Spine Group — Carmel, Indiana (14.0 mi) · Sponsor: Hospital for Special Surgery, New York
See eligibility & contact on ClinicalTrials.gov (NCT06491030)

Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections

Methicillin Resistant Staphylococcus Aureus, Osteomyelitis Acute Phase 4 Interventional 100 participants sought
Riley Hospital for Children — Indianapolis, Indiana (0.9 mi) · Sponsor: Indiana University
See eligibility & contact on ClinicalTrials.gov (NCT06982105)

A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-181 in Subjects With Phenylketonuria

Phenylketonuria Phase 1 Interventional 20 participants sought
Indiana University — Indianapolis, Indiana (0.9 mi) · Sponsor: Agios Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07241234)

Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction Phase 3 Interventional 2,000 participants sought
St. Vincent Medical Group — Indianapolis, Indiana (0.9 mi) · Sponsor: Uppsala University
See eligibility & contact on ClinicalTrials.gov (NCT02901184)
Actively enrolling

Studies you may be able to join near Indianapolis

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Indianapolis

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

DelRicht Research of Indianapolis Clinical Trials

★ 4.8
2162 N Meridian St Ste B, Indianapolis, IN 46202
(504) 383-8674
"The staff is very helpful and attentive. Having a wonderful experience so far."
— Chrystopher Burns, 5★

Indiana CTSI

★ 4.0
410 W 10th St Ste 1000, Indianapolis, IN 46202
(317) 278-2874
"This is for the lawn outside. Chill spot to sit in the shade and relax for a moment. The mist from the spillway makes it feel relatively fresh and co…"
— Autumn McDonald, 4★

Stark Neurosciences Research Institute

★ 5.0
NB Building, 320 W 15th St #414, Indianapolis, IN 46202
(317) 278-7000
"Pretty neat building for the first time going inside, but a new hospital addition is being built next door which is 17 floors and should be finished …"
— Alex Hartman, 5★

Regenstrief Institute

★ 3.9
1101 W 10th St, Indianapolis, IN 46202
(317) 274-9000

Lilly Research Laboratories

★ 4.6
307 E Merrill St, Indianapolis, IN 46225
(317) 276-2000
"There was an issue with my mother's insulin pen today. She is visiting from out of state. She called and reported it and was attempting to requesting…"
— Michael Mannino, 1★

Indiana Alzheimer Disease Center

355 W 16th St, Indianapolis, IN 46202
(317) 963-5500

Indiana University Melvin and Bren Simon Comprehensive Cancer Center

★ 4.2 (59 reviews)
535 Barnhill Dr, Indianapolis, IN 46202
(888) 600-4822
"Worst experience. They don’t respect"
— Mike Smith, 1★

Indiana Center for Systems Biology and Personalized Medicine

★ 4.0
Walker Plaza, 719 Indiana Ave, Indianapolis, IN 46202
(317) 278-7604
"Do they store body parts here too. Like the research center in Chicago.?"
— El 701 Viajes Privados, 4★

IU Health Neuroscience Center

★ 3.8
355 W 15th St, Indianapolis, IN 46202
(317) 948-5450
"After 10 years of dealing with a brain tumor I made the decision to have it surgically removed by Neurosurgeon Dr Almeida. It was a complicated surge…"
— Dusty Roads, 5★

Clinical trials in Indianapolis: what's recruiting

The Indianapolis area currently has 915 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Indianapolis, the most active research areas are:

  • Cancer & Oncology10 studies
  • Brain & Mental Health3 studies
  • Lungs & Breathing2 studies
  • Immune & Skin2 studies
  • Heart & Vascular2 studies

Every listing shows the study phase, the recruiting site and its distance from Indianapolis, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Indianapolis

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Indianapolis participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Indianapolis pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
How do I join a study in Indianapolis, IN?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Indianapolis?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Indianapolis.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Indianapolis typically complete one or two studies per year.

Paid clinical trials near Indianapolis

Other metros within reach

Lafayette, IN37 Fort Wayne, IN115 Louisville, KY566 Cincinnati, OH1,127 South Bend, IN110 Elkhart, IN110 Dayton, OH310 Champaign, IL169

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Indianapolis Bladder Issues Due To Spinal Cord Injury in Indianapolis All conditions

More of IN

Fort Wayne115 Elkhart110 South Bend110 Evansville66 Lafayette37

New paid studies open every week

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