Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/IN/Indianapolis
Updated November 2026 from ClinicalTrials.gov

Paid Clinical Trials in Indianapolis, IN

Studies commonly pay $75 to $4,500 per completed study

953 clinical trials are currently recruiting participants within 30 miles of Indianapolis. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

953studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Indianapolis right now

Top 25 of 953 recruiting studies, sorted by proximity — each links to its official registry page

Clinical Decision Support Tool in PARDS Pilot Study

Ventilation Therapy; Complications, Ventilator-Induced Lung Injury N/A Interventional 180 participants sought
Riley Hospital for Children — Indianapolis, Indiana (0.9 mi) · Sponsor: Children's Hospital Los Angeles
See eligibility & contact on ClinicalTrials.gov (NCT04068012)

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

Brain Tumor, Recurrent, Brain Tumor N/A Observational 600 participants sought
Indiana University, IU Health Methodist Hospital — Indianapolis, Indiana (0.9 mi) · Sponsor: GT Medical Technologies, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04427384)

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A

Von Willebrand Disease, Type 3, Concomitant VWD and Hemophilia Phase 1 Interventional 40 participants sought
Innovative Hematology, Inc. (IHI) — Indianapolis, Indiana (0.9 mi) · Sponsor: Bleeding and Clotting Disorders Institute Peoria, Illinois
See eligibility & contact on ClinicalTrials.gov (NCT05500807)

Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer

Endometrial Cancer Phase 2, Phase 3 Interventional 268 participants sought
Indiana University — Indianapolis, Indiana (0.9 mi) · Sponsor: Kartos Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05797831)

Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma

Large Cell Lymphoma, Diffuse, Relapsed Cancer Phase 2 Interventional 35 participants sought
Indiana University Melvin and Bren Simon Comprehensive Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: Dipenkumar Modi
See eligibility & contact on ClinicalTrials.gov (NCT05852717)

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

Colitis, Ulcerative Phase 3 Interventional 882 participants sought
IU Health University Hospital — Indianapolis, Indiana (0.9 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07196748)

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
Indiana University Health Riley Hospital for Children — Indianapolis, Indiana (0.9 mi) · Sponsor: Medtronic MiniMed, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07228117)

A Study of Buntanetap in Participants With PD

Parkinson's Disease (PD), Deep Brain Stimulation Phase 2, Phase 3 Interventional 500 participants sought
Josephson Wallack Munshower Neurology, P.C. — Indianapolis, Indiana (0.9 mi) · Sponsor: Annovis Bio Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07284784)

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2

Post Operative Surgical Site Infection Phase 3 Interventional 600 participants sought
Indiana University School of Medicine - Methodist Hospital — Indianapolis, Indiana (0.9 mi) · Sponsor: Major Extremity Trauma Research Consortium
See eligibility & contact on ClinicalTrials.gov (NCT04678154)

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer, c-MET Phase 3 Interventional 768 participants sought
Investigative Clinical Research of Indiana - Indianapolis /ID# 260468 — Indianapolis, Indiana (0.9 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT04928846)

Options for Pain Management Using Nonpharmacological Strategies

Pain N/A Interventional 296 participants sought
Richard L. Roudebush VA Medical Center, Indianapolis, IN — Indianapolis, Indiana (0.9 mi) · Sponsor: VA Office of Research and Development
See eligibility & contact on ClinicalTrials.gov (NCT05563792)

Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8 Phase 3 Interventional 428 participants sought
Indiana University/Melvin and Bren Simon Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05646316)

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)

Vulvar Diseases, HPV Infection Phase 2 Interventional 27 participants sought
Ascension St. Vincent — Indianapolis, Indiana (0.9 mi) · Sponsor: Frantz Viral Therapeutics, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06075264)

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Solid Tumor, Adult, Metastatic Breast Cancer Phase 1 Interventional 392 participants sought
Indiana University Simon Comprehensive Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
See eligibility & contact on ClinicalTrials.gov (NCT06625775)

HER2 Vaccine for Locally Advanced Breast Cancer

Breast Cancer, HER2-positive Breast Cancer Phase 1 Interventional 36 participants sought
Indiana University Melvin & Bren Simon Comprehensive Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: Pravin T.P Kaumaya
See eligibility & contact on ClinicalTrials.gov (NCT06949410)

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Breast Neoplasms, Triple Negative Breast Neoplasms Phase 3 Interventional 2,400 participants sought
Franciscan Health ( Site 0077) — Indianapolis, Indiana (0.9 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06966700)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
Indiana University Melvin and Bren Simon Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

Study of Resmetirom in Children and Adolescents With MASH

MASH, MASH - Metabolic Dysfunction-Associated Steatohepatitis Phase 2 Interventional 61 participants sought
Riley Hospital for Children at IU Health — Indianapolis, Indiana (0.9 mi) · Sponsor: Madrigal Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07763015)

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

Pulmonary Invasive Fungal Infections, Pulmonary Invasive Aspergillosis N/A Observational 400 participants sought
Indiana University School of Medicine — Indianapolis, Indiana (0.9 mi) · Sponsor: Arkansas Children's Hospital Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT03827694)

Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder

Schizophrenia, Bipolar I Disorder Phase 3 Interventional 220 participants sought
Alkermes Investigator Site — Indianapolis, Indiana (0.9 mi) · Sponsor: Alkermes, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05303064)

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

Cancer, Melanoma Stage III Phase 1, Phase 2 Interventional 240 participants sought
IU Simon Comprehensive Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: Krystal Biotech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05970497)

Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up

Asthma, Pulmonary Function N/A Observational 225 participants sought
Indiana University — Indianapolis, Indiana (0.9 mi) · Sponsor: Oregon Health and Science University
See eligibility & contact on ClinicalTrials.gov (NCT06106646)

rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant Depression

Depression, Treatment Resistant N/A Interventional 20 participants sought
Goodman Hall Neuroscience Center — Indianapolis, Indiana (0.9 mi) · Sponsor: Indiana University
See eligibility & contact on ClinicalTrials.gov (NCT06511544)
Actively enrolling

Studies you may be able to join near Indianapolis

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Indianapolis

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

DelRicht Research of Indianapolis Clinical Trials

★ 4.8
2162 N Meridian St Ste B, Indianapolis, IN 46202
(504) 383-8674
"The staff is very helpful and attentive. Having a wonderful experience so far."
— Chrystopher Burns, 5★

Indiana CTSI

★ 4.0
410 W 10th St Ste 1000, Indianapolis, IN 46202
(317) 278-2874
"This is for the lawn outside. Chill spot to sit in the shade and relax for a moment. The mist from the spillway makes it feel relatively fresh and co…"
— Autumn McDonald, 4★

Stark Neurosciences Research Institute

★ 5.0
NB Building, 320 W 15th St #414, Indianapolis, IN 46202
(317) 278-7000
"Pretty neat building for the first time going inside, but a new hospital addition is being built next door which is 17 floors and should be finished …"
— Alex Hartman, 5★

Regenstrief Institute

★ 3.9
1101 W 10th St, Indianapolis, IN 46202
(317) 274-9000

Lilly Research Laboratories

★ 4.6
307 E Merrill St, Indianapolis, IN 46225
(317) 276-2000
"There was an issue with my mother's insulin pen today. She is visiting from out of state. She called and reported it and was attempting to requesting…"
— Michael Mannino, 1★

Indiana Alzheimer Disease Center

355 W 16th St, Indianapolis, IN 46202
(317) 963-5500

Indiana University Melvin and Bren Simon Comprehensive Cancer Center

★ 4.2 (59 reviews)
535 Barnhill Dr, Indianapolis, IN 46202
(888) 600-4822
"Worst experience. They don’t respect"
— Mike Smith, 1★

Indiana Center for Systems Biology and Personalized Medicine

★ 4.0
Walker Plaza, 719 Indiana Ave, Indianapolis, IN 46202
(317) 278-7604
"Do they store body parts here too. Like the research center in Chicago.?"
— El 701 Viajes Privados, 4★

IU Health Neuroscience Center

★ 3.8
355 W 15th St, Indianapolis, IN 46202
(317) 948-5450
"After 10 years of dealing with a brain tumor I made the decision to have it surgically removed by Neurosurgeon Dr Almeida. It was a complicated surge…"
— Dusty Roads, 5★

Clinical trials in Indianapolis: what's recruiting

The Indianapolis area currently has 953 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Indianapolis, the most active research areas are:

  • Cancer & Oncology11 studies
  • Brain & Mental Health3 studies
  • Diabetes & Metabolism2 studies
  • Lungs & Breathing2 studies
  • Immune & Skin1 studies

Every listing shows the study phase, the recruiting site and its distance from Indianapolis, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Indianapolis

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Indianapolis participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Indianapolis pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
How do I join a study in Indianapolis, IN?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Indianapolis?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Indianapolis.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Indianapolis typically complete one or two studies per year.

Paid clinical trials near Indianapolis

Other metros within reach

Lafayette, IN34 Fort Wayne, IN117 Louisville, KY559 Cincinnati, OH1,128 South Bend, IN105 Elkhart, IN105 Dayton, OH308 Champaign, IL176

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Indianapolis Bladder Issues Due To Spinal Cord Injury in Indianapolis All conditions

More of IN

Fort Wayne117 Elkhart105 South Bend105 Evansville77 Lafayette34

New paid studies open every week

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