Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/IL/Champaign
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Champaign, IL

Studies commonly pay $75 to $4,500 per completed study

169 clinical trials are currently recruiting participants within 30 miles of Champaign. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

169studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Champaign right now

Top 25 of 169 recruiting studies, sorted by proximity — each links to its official registry page

Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib

Carcinoma, Non-Small Cell Lung Phase 1, Phase 2 Interventional 158 participants sought
Carle Cancer Institute — Urbana, Illinois (3.5 mi) · Sponsor: Genprex, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04486833)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Champaign, Illinois (1.6 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma, Stage II Pancreatic Cancer AJCC v8 Phase 3 Interventional 356 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06958328)

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 189 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT02734537)

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Malignant Female Reproductive System Neoplasm, Malignant Solid Neoplasm Phase 2 Interventional 70 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06126276)

Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis Phase 2 Interventional 165 participants sought
Christie Clinic on University /ID# 277871 — Champaign, Illinois (1.6 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT07230288)

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Malignancy N/A Observational 240 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04242095)

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

Epithelial Ovarian Cancer, Fallopian Tube Cancer Phase 2 Interventional 140 participants sought
Carle Foundation Hospital /ID# 276470 — Urbana, Illinois (3.5 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06890338)

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma, Stage I Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8 Phase 3 Interventional 228 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06992427)

Fall Prevention Among People With Spinal Cord Injury and Multiple Sclerosis Who Use Wheelchairs and Scooters

Spinal Cord Injuries (SCI), Multiple Sclerosis N/A Interventional 120 participants sought
Disability Participation and Quality of Life (DPQOL) Laboratory — Urbana, Illinois (3.5 mi) · Sponsor: University of Illinois at Urbana-Champaign
See eligibility & contact on ClinicalTrials.gov (NCT07167680)

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

Metastatic Salivary Gland Carcinoma, Recurrent Salivary Gland Carcinoma Phase 2 Interventional 146 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05408845)

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Classic Follicular Lymphoma, Follicular Lymphoma With Unusual Cytological Features Phase 3 Interventional 600 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06337318)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,209 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05946213)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05561387)

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

Breast Cancer, Metastatic Breast Cancer Phase 3 Interventional 404 participants sought
Carle Foundation Cancer Institute-Urbana — Urbana, Illinois (3.5 mi) · Sponsor: BriaCell Therapeutics Corporation
See eligibility & contact on ClinicalTrials.gov (NCT06072612)

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

Colorectal Cancer Stage II, Colorectal Cancer Stage III Phase 3 Interventional 1,057 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT07018869)

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma Phase 3 Interventional 255 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07198074)

Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer

Locally Advanced Adrenal Cortical Carcinoma, Metastatic Adrenal Cortical Carcinoma Phase 2 Interventional 48 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06900595)

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Stage I Breast Cancer Phase 3 Interventional 1,670 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04852887)

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

Cardiotoxicity, HER2/Neu Positive Phase 3 Interventional 491 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03418961)

AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer

Epithelial Ovarian Cancer Phase 3 Interventional 1,100 participants sought
Research Site — Urbana, Illinois (3.5 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07218809)
Actively enrolling

Studies you may be able to join near Champaign

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Champaign

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Cline Center for Advanced Social Research

★ 3.7
2001 S 1st St Ste 207, Champaign, IL 61820
(217) 265-7845

Christie Clinic Clinical Research

1801 W Windsor Rd, Champaign, IL 61822
(217) 366-2200

Alcohol Research Lab

Psychology Building, 603 E Daniel St Room 23, Champaign, IL 61820
(217) 300-5850

Coordinated Science Laboratory

★ 4.6
1308 W Main St Rm B16, Urbana, IL 61801
(217) 333-2511
"Lots of offices and an auditorium."
— Dave Vesely, 4★

U of I Urbana-Champaign Cancer Center at Illinois

Beckman Institute for Advanced Science and Technology, 405 N Mathews Ave, Urbana, IL 61801
(217) 300-6100

University of Illinois Counseling Center

★ 2.4 (18 reviews)
610 E John St Rm 206, Champaign, IL 61820
(217) 333-3704
"Absurd contract they try to get you to sign which puts everything against the student seeking help. They pretend to not know any better. Ludicrous."
— John B, 1★

Carle Cancer Institute Urbana

★ 4.3
509 W University Ave, Urbana, IL 61801
(217) 383-3010

Christie Clinic Department of Dermatology- Cosmetic Center

★ 4.3
101 W University Ave, Champaign, IL 61820
(217) 366-1248

Carle Neuroscience Institute

★ 3.5
610 N Lincoln Ave, Urbana, IL 61801
(217) 383-6555
"It's clean, and seemed quiet. I had a great doctor that listened to me. The front desk staff seemed respectful."
— Samantha Ragazincky, 5★

Clinical trials in Champaign: what's recruiting

The Champaign area currently has 169 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Champaign, the most active research areas are:

  • Cancer & Oncology20 studies
  • Lungs & Breathing1 studies
  • Liver & Kidney1 studies
  • Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from Champaign, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Champaign

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Champaign participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Champaign?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Champaign?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Champaign?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Champaign.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Champaign typically complete one or two studies per year.

Paid clinical trials near Champaign

Other metros within reach

Joliet, IL514 Springfield, IL188 Lafayette, IN37 Peoria, IL219 Naperville, IL2,362 Aurora, IL614 Chicago, IL2,448 Indianapolis, IN915

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Champaign Bladder Issues Due To Spinal Cord Injury in Champaign All conditions

More of IL

Chicago2,448 Naperville2,362 Aurora614 Joliet514 Round Lake Beach472 Peoria219 Springfield188 Rockford113

New paid studies open every week

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