Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/IL/Champaign
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Champaign, IL

Studies commonly pay $75 to $4,500 per completed study

168 clinical trials are currently recruiting participants within 30 miles of Champaign. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

168studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Champaign right now

Top 25 of 168 recruiting studies, sorted by proximity — each links to its official registry page

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma Phase 2 Interventional 81 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05112601)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Champaign, Illinois (1.6 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

Non-Small Cell Lung Cancer (NSCLC) Phase 3 Interventional 750 participants sought
Local Institution - 0423 — Urbana, Illinois (3.5 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT07361510)

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Malignant Female Reproductive System Neoplasm, Malignant Solid Neoplasm Phase 2 Interventional 70 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06126276)

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma Phase 3 Interventional 364 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT04510597)

Fall Prevention Among People With Spinal Cord Injury and Multiple Sclerosis Who Use Wheelchairs and Scooters

Spinal Cord Injuries (SCI), Multiple Sclerosis N/A Interventional 120 participants sought
Disability Participation and Quality of Life (DPQOL) Laboratory — Urbana, Illinois (3.5 mi) · Sponsor: University of Illinois at Urbana-Champaign
See eligibility & contact on ClinicalTrials.gov (NCT07167680)

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

Multiple conditions Phase 2 Interventional 98 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06532279)

Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

Grade 3b Follicular Lymphoma, High Grade B-Cell Lymphoma Phase 2 Interventional 227 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05890352)

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Breast Carcinoma, Colorectal Carcinoma N/A Observational 2,000 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT06418204)

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

Cigarette Smoking-Related Carcinoma Phase 3 Interventional 600 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05008848)

Mindfulness Walking Intervention to Enhance Resilience (iWalk)

Neurodegenerative Disease, EEG N/A Interventional 90 participants sought
University of Illinois Urbana-Champaign — Urbana, Illinois (3.5 mi) · Sponsor: University of Illinois at Urbana-Champaign
See eligibility & contact on ClinicalTrials.gov (NCT07285954)

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

Locally Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma Phase 2 Interventional 122 participants sought
Carle Cancer Center NCI Community Oncology Research Program — Urbana, Illinois (3.5 mi) · Sponsor: Academic and Community Cancer Research United
See eligibility & contact on ClinicalTrials.gov (NCT05168163)

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Endometrial Carcinoma, Endometrial Clear Cell Adenocarcinoma Phase 3 Interventional 360 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05256225)

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 Phase 3 Interventional 3,680 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06058377)

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Locally Advanced Cervical Adenocarcinoma, Locally Advanced Cervical Adenosquamous Carcinoma Phase 3 Interventional 336 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07061977)

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

Advanced Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma Phase 2 Interventional 46 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT03191149)

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

Cardiotoxicity, HER2/Neu Positive Phase 3 Interventional 491 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03418961)

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma N/A Observational 800 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: University of Rochester
See eligibility & contact on ClinicalTrials.gov (NCT06073431)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT01810913)

Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

Angioimmunoblastic T-cell Lymphoma, Enteropathy-Associated T-Cell Lymphoma Phase 2 Interventional 170 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04803201)
Actively enrolling

Studies you may be able to join near Champaign

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Champaign

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Cline Center for Advanced Social Research

★ 3.7
2001 S 1st St Ste 207, Champaign, IL 61820
(217) 265-7845

Christie Clinic Clinical Research

1801 W Windsor Rd, Champaign, IL 61822
(217) 366-2200

Alcohol Research Lab

Psychology Building, 603 E Daniel St Room 23, Champaign, IL 61820
(217) 300-5850

Coordinated Science Laboratory

★ 4.6
1308 W Main St Rm B16, Urbana, IL 61801
(217) 333-2511
"Lots of offices and an auditorium."
— Dave Vesely, 4★

U of I Urbana-Champaign Cancer Center at Illinois

Beckman Institute for Advanced Science and Technology, 405 N Mathews Ave, Urbana, IL 61801
(217) 300-6100

University of Illinois Counseling Center

★ 2.4 (18 reviews)
610 E John St Rm 206, Champaign, IL 61820
(217) 333-3704
"Absurd contract they try to get you to sign which puts everything against the student seeking help. They pretend to not know any better. Ludicrous."
— John B, 1★

Carle Cancer Institute Urbana

★ 4.3
509 W University Ave, Urbana, IL 61801
(217) 383-3010

Christie Clinic Department of Dermatology- Cosmetic Center

★ 4.3
101 W University Ave, Champaign, IL 61820
(217) 366-1248

Carle Neuroscience Institute

★ 3.5
610 N Lincoln Ave, Urbana, IL 61801
(217) 383-6555
"It's clean, and seemed quiet. I had a great doctor that listened to me. The front desk staff seemed respectful."
— Samantha Ragazincky, 5★

Clinical trials in Champaign: what's recruiting

The Champaign area currently has 168 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Champaign, the most active research areas are:

  • Cancer & Oncology18 studies
  • Liver & Kidney2 studies
  • Lungs & Breathing1 studies
  • Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from Champaign, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Champaign

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Champaign participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Champaign?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Champaign?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Champaign?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Champaign.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Champaign typically complete one or two studies per year.

Paid clinical trials near Champaign

Other metros within reach

Joliet, IL514 Springfield, IL181 Lafayette, IN36 Peoria, IL219 Naperville, IL2,351 Aurora, IL614 Chicago, IL2,437 Indianapolis, IN921

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Champaign Bladder Issues Due To Spinal Cord Injury in Champaign All conditions

More of IL

Chicago2,437 Naperville2,351 Aurora614 Joliet514 Round Lake Beach466 Peoria219 Springfield181 Rockford110

New paid studies open every week

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