Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/IL/Champaign
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Champaign, IL

Studies commonly pay $75 to $4,500 per completed study

167 clinical trials are currently recruiting participants within 30 miles of Champaign. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

167studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Champaign right now

Top 25 of 167 recruiting studies, sorted by proximity — each links to its official registry page

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Multiple conditions Phase 2 Interventional 150 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05136196)

Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment

Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm N/A Interventional 600 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06279013)

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma Phase 3 Interventional 1,450 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT04566328)

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

Breast Neoplasms Phase 3 Interventional 558 participants sought
Carle Foundation Hospital d/b/a Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: BioNTech SE
See eligibility & contact on ClinicalTrials.gov (NCT07173751)

A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.

Chronic Kidney Disease and Hypertension Phase 2 Interventional 218 participants sought
Research Site — Champaign, Illinois (1.6 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07222917)

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Classic Follicular Lymphoma, Follicular Lymphoma With Unusual Cytological Features Phase 3 Interventional 600 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06337318)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT01810913)

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Brain Metastases Phase 3 Interventional 206 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: Canadian Cancer Trials Group
See eligibility & contact on ClinicalTrials.gov (NCT03550391)

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04251052)

An Individualized-health eLibrary App for People With Multiple Sclerosis

Multiple Sclerosis N/A Interventional 60 participants sought
University of Illinois Urbana-Champaign — Champaign, Illinois (1.6 mi) · Sponsor: University of Illinois at Urbana-Champaign
See eligibility & contact on ClinicalTrials.gov (NCT05124600)

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Breast Carcinoma, Colorectal Carcinoma N/A Observational 2,000 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT06418204)

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

Locally Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma Phase 2 Interventional 122 participants sought
Carle Cancer Center NCI Community Oncology Research Program — Urbana, Illinois (3.5 mi) · Sponsor: Academic and Community Cancer Research United
See eligibility & contact on ClinicalTrials.gov (NCT05168163)

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 Phase 2 Interventional 474 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06632977)

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

Breast Cancer, Locally Advanced Breast Cancer Phase 3 Interventional 1,000 participants sought
Clinical Trial Site — Urbana, Illinois (3.5 mi) · Sponsor: Olema Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07085767)

Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms

Alcohol Drinking, Alcohol Intoxication N/A Observational 240 participants sought
University of Illinois at Urbana-Champaign — Champaign, Illinois (1.6 mi) · Sponsor: University of Illinois at Urbana-Champaign
See eligibility & contact on ClinicalTrials.gov (NCT05692830)

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Stage I Breast Cancer Phase 3 Interventional 1,670 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04852887)

Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)

Cognitive Change, Diet, Healthy N/A Interventional 72 participants sought
University of Illinois at Urbana-Champaign — Urbana, Illinois (3.5 mi) · Sponsor: University of Illinois at Urbana-Champaign
See eligibility & contact on ClinicalTrials.gov (NCT06605898)

Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL

Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia Phase 3 Interventional 466 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT07321652)

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Intracranial Meningioma, Recurrent Meningioma Phase 2 Interventional 124 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT02523014)

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Extensive Stage Lung Small Cell Carcinoma Phase 2, Phase 3 Interventional 138 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04402788)
Google-rated

Top-rated research centers in Champaign

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Cline Center for Advanced Social Research

★ 3.7
2001 S 1st St Ste 207, Champaign, IL 61820
(217) 265-7845

Christie Clinic Clinical Research

1801 W Windsor Rd, Champaign, IL 61822
(217) 366-2200

Alcohol Research Lab

Psychology Building, 603 E Daniel St Room 23, Champaign, IL 61820
(217) 300-5850

Coordinated Science Laboratory

★ 4.6
1308 W Main St Rm B16, Urbana, IL 61801
(217) 333-2511
"Lots of offices and an auditorium."
— Dave Vesely, 4★

U of I Urbana-Champaign Cancer Center at Illinois

Beckman Institute for Advanced Science and Technology, 405 N Mathews Ave, Urbana, IL 61801
(217) 300-6100

University of Illinois Counseling Center

★ 2.4 (18 reviews)
610 E John St Rm 206, Champaign, IL 61820
(217) 333-3704
"Absurd contract they try to get you to sign which puts everything against the student seeking help. They pretend to not know any better. Ludicrous."
— John B, 1★

Carle Cancer Institute Urbana

★ 4.3
509 W University Ave, Urbana, IL 61801
(217) 383-3010

Christie Clinic Department of Dermatology- Cosmetic Center

★ 4.3
101 W University Ave, Champaign, IL 61820
(217) 366-1248

Carle Neuroscience Institute

★ 3.5
610 N Lincoln Ave, Urbana, IL 61801
(217) 383-6555
"It's clean, and seemed quiet. I had a great doctor that listened to me. The front desk staff seemed respectful."
— Samantha Ragazincky, 5★

Clinical trials in Champaign: what's recruiting

The Champaign area currently has 167 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Champaign, the most active research areas are:

  • Cancer & Oncology16 studies
  • Liver & Kidney2 studies
  • Heart & Vascular1 studies
  • Lungs & Breathing1 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Champaign, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Champaign

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Champaign participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Champaign?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Champaign?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Champaign?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Champaign.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Champaign typically complete one or two studies per year.

Paid clinical trials near Champaign

Other metros within reach

Joliet, IL521 Springfield, IL192 Lafayette, IN40 Peoria, IL219 Naperville, IL2,362 Aurora, IL617 Chicago, IL2,449 Indianapolis, IN915

More of IL

Chicago2,449 Naperville2,362 Aurora617 Joliet521 Round Lake Beach455 Peoria219 Springfield192 Rockford115

New paid studies open every week

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