Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/IA/Des Moines
Updated November 2026 from ClinicalTrials.gov

Paid Clinical Trials in Des Moines, IA

Studies commonly pay $75 to $4,500 per completed study

229 clinical trials are currently recruiting participants within 30 miles of Des Moines. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

229studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Des Moines right now

Top 25 of 229 recruiting studies, sorted by proximity — each links to its official registry page

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma Phase 3 Interventional 5,951 participants sought
Blank Children's Hospital — Des Moines, Iowa (1.9 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT03959085)

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia (CLL) Phase 2 Interventional 75 participants sought
Des Moines Oncology Research Association /ID# 232606 — Des Moines, Iowa (1.9 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT04895436)

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

Cigarette Smoking-Related Carcinoma Phase 3 Interventional 600 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05008848)

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma Phase 3 Interventional 1,273 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03678025)

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Childhood Medulloblastoma Phase 3 Interventional 225 participants sought
Blank Children's Hospital — Des Moines, Iowa (1.9 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT05382338)

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism Phase 2, Phase 3 Interventional 2,800 participants sought
Iowa Diabetes and Endocrinology Research Center /ID# 256750 — West Des Moines, Iowa (5.2 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06345339)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
Mission Blood & Cancer Care ( Site 0114) — Waukee, Iowa (14.5 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Phase 3 Interventional 1,200 participants sought
University of Iowa Health Care. ( Site 0057) — Waukee, Iowa (14.5 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06136559)

Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease

Arterial Disease of Legs, Below-the-knee Obstruction N/A Interventional 368 participants sought
Unity Point Health Des Moines — Des Moines, Iowa (1.9 mi) · Sponsor: Concept Medical Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06182397)

A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma Phase 3 Interventional 700 participants sought
Mission Cancer Blood University of Iowa Health Care — Waukee, Iowa (14.5 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07518186)

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Mitral Valve Regurgitation N/A Interventional 1,056 participants sought
MercyOne Des Moines Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: Medtronic Cardiovascular
See eligibility & contact on ClinicalTrials.gov (NCT03242642)

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum N/A Interventional 9,500 participants sought
Mercy Medical Center - Des Moines — Des Moines, Iowa (1.9 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05080673)

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis Phase 3 Interventional 2,150 participants sought
Akero Clinical Study Site — West Des Moines, Iowa (5.2 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06528314)

Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure

Healthy Adult Participants N/A Observational 15 participants sought
Decentralized / At-Home Participation (U.S.) — Des Moines, Iowa (1.9 mi) · Sponsor: Ecotera Health LLC
See eligibility & contact on ClinicalTrials.gov (NCT07775495)

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma Phase 3 Interventional 364 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT04510597)

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

Oligometastatic Prostate Cancer (OMPC) Phase 3 Interventional 450 participants sought
Unity Point Clinic — Des Moines, Iowa (1.9 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT05939414)

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Heart Failure Phase 3 Interventional 4,200 participants sought
The Iowa Clinic, PC — West Des Moines, Iowa (5.2 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT06935370)

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Phase 3 Interventional 247 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04269902)

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

Multiple conditions Phase 2 Interventional 98 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06532279)

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Colorectal Neoplasms Phase 3 Interventional 1,000 participants sought
Mission Cancer Blood — Waukee, Iowa (14.5 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06662786)

Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL

Relapsed or Refractory Aggressive B-Cell Non-Hodgkins Lymphoma Phase 2 Interventional 130 participants sought
Mission Blood and Cancer - MercyOne Cancer Center — Waukee, Iowa (14.5 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06806033)

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma Phase 3 Interventional 62 participants sought
Blank Children's Hospital — Des Moines, Iowa (1.9 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT05235165)

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

Non-small Cell Lung Cancer Phase 3 Interventional 320 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: Canadian Cancer Trials Group
See eligibility & contact on ClinicalTrials.gov (NCT06686771)

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

Mantle Cell Lymphoma, B Cell Lymphoma Phase 3 Interventional 300 participants sought
Mission Cancer and Blood — Waukee, Iowa (14.5 mi) · Sponsor: BeOne Medicines
See eligibility & contact on ClinicalTrials.gov (NCT06742996)

A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

Metastatic Castration-resistant Prostatic Neoplasms Phase 3 Interventional 1,203 participants sought
Mission Cancer Blood — Waukee, Iowa (14.5 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07164443)
Actively enrolling

Studies you may be able to join near Des Moines

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Des Moines

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

ICTS Research Clinic Integrated Clinical Trial Services, Inc.

★ 3.7
1031 Office Park Rd #9, West Des Moines, IA 50265
(515) 223-2300
"The first time I started with Integrated Clinical Trial Services my EKG showed I had a concern. I went to Iowa Heart and was tested/treated and put …"
— kenn bekker, 5★

Heartland Medical Research

1230 8th St Ste 200, West Des Moines, IA 50265
(515) 225-6050

Des Moines University Clinic

★ 4.2
3200 Grand Ave, Des Moines, IA 50312
(515) 271-1700
"It's the osteopathic college renamed. The best part of it is the osteopathic manipulation department. I'm seeing one that can do myofascial and she's…"
— Diane Falkoski, 5★

Iowa Oncology Research Association

1221 Pleasant St #450, Des Moines, IA 50309
(515) 241-3305

The Iowa Clinic Research - West Des Moines Campus

5950 University Ave, West Des Moines, IA 50266
(515) 875-9815

OpenLoop Health

★ 4.5
317 6th Ave #400, Des Moines, IA 50309
(855) 597-1248

The Iowa Clinic Research - Ankeny Campus

1410 SW Tradition Dr, Ankeny, IA 50023
(515) 875-9815

Mission Cancer + Blood

★ 4.0 (22 reviews)
110 E Court Ave Ste. 200, Des Moines, IA 50309
(515) 282-2921
"Rating solely on disability access. This is an extremely difficult place to access, starting in the parking lot. The disabled parking is as far as p…"
— Dan Hodge, 2★

Dr. Robert R. Shreck, MD

★ 5.0 (2 reviews)
1221 Pleasant St Ste 100, Des Moines, IA 50309
(515) 282-2921
"Best doctor and friend all around Danny parnell"
— Danny Parnell, 5★

Clinical trials in Des Moines: what's recruiting

The Des Moines area currently has 229 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Des Moines, the most active research areas are:

  • Cancer & Oncology17 studies
  • Liver & Kidney2 studies
  • Diabetes & Metabolism1 studies
  • Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from Des Moines, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Des Moines

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Des Moines participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Des Moines pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Des Moines safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Des Moines, IA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Des Moines typically complete one or two studies per year.

Paid clinical trials near Des Moines

Other metros within reach

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By condition

Eligibility and exclusions, condition by condition

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More of IA

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