Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/IA/Des Moines
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Des Moines, IA

Studies commonly pay $75 to $4,500 per completed study

220 clinical trials are currently recruiting participants within 30 miles of Des Moines. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

220studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Des Moines right now

Top 25 of 220 recruiting studies, sorted by proximity — each links to its official registry page

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Blank Children's Hospital — Des Moines, Iowa (1.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer Phase 3 Interventional 600 participants sought
Mission Cancer + Blood - IMMC — Des Moines, Iowa (1.9 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06793215)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Des Moines, Iowa (1.9 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma Phase 3 Interventional 1,524 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT07200830)

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

Type 2 Diabetes, Cortisol Excess Phase 2 Interventional 1,500 participants sought
Iowa Diabetes and Endocrinology Research Center — West Des Moines, Iowa (5.2 mi) · Sponsor: Sparrow Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07296484)

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Malignant Female Reproductive System Neoplasm, Malignant Solid Neoplasm Phase 2 Interventional 70 participants sought
UI Health Care Mission Cancer and Blood - Des Moines Clinic — Des Moines, Iowa (1.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06126276)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Des Moines, Iowa (1.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06129864)

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism Phase 2, Phase 3 Interventional 2,800 participants sought
Iowa Diabetes and Endocrinology Research Center /ID# 256750 — West Des Moines, Iowa (5.2 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06345339)

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Low Grade Astrocytoma, Low Grade Glioma Phase 3 Interventional 170 participants sought
Blank Children's Hospital — Des Moines, Iowa (1.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04166409)

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis Phase 3 Interventional 2,150 participants sought
Akero Clinical Study Site — West Des Moines, Iowa (5.2 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06528314)

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Mitral Valve Regurgitation N/A Interventional 1,056 participants sought
MercyOne Des Moines Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: Medtronic Cardiovascular
See eligibility & contact on ClinicalTrials.gov (NCT03242642)

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

Metabolic Dysfunction-Associated Steatotic Liver Disease Phase 3 Interventional 4,500 participants sought
Iowa Diabetes and Endocrinology Research Center — West Des Moines, Iowa (5.2 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07165028)

Quality of End-of-Life Care for Children With Cancer

Childhood Hematopoietic and Lymphatic System Neoplasm, Childhood Malignant Solid Neoplasm N/A Observational 2,425 participants sought
Blank Children's Hospital — Des Moines, Iowa (1.9 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT07412002)

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma Phase 3 Interventional 364 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT04510597)

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

Metastatic Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8 Phase 2 Interventional 240 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05327686)

Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital

COPD N/A Interventional 70 participants sought
Central Iowa Hospital Corp - UnityPoint Health — Des Moines, Iowa (1.9 mi) · Sponsor: Fisher and Paykel Healthcare
See eligibility & contact on ClinicalTrials.gov (NCT07222410)

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

Multiple conditions Phase 2 Interventional 98 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06532279)

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Colorectal Neoplasms Phase 3 Interventional 1,000 participants sought
Mission Cancer Blood — Waukee, Iowa (14.5 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06662786)

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

Metastatic Digestive System Neuroendocrine Tumor G1, Metastatic Digestive System Neuroendocrine Tumor G2 Phase 2 Interventional 100 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05773274)

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Arrhythmia, Bradycardia N/A Observational 20,000 participants sought
Research site — West Des Moines, Iowa (5.2 mi) · Sponsor: Medtronic
See eligibility & contact on ClinicalTrials.gov (NCT00271180)

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

Metabolic Dysfunction Associated Steatohepatitis Phase 3 Interventional 1,590 participants sought
Iowa Diabetes and Endocrinology Research Center — West Des Moines, Iowa (5.2 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT06632457)
Actively enrolling

Studies you may be able to join near Des Moines

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Des Moines

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

ICTS Research Clinic Integrated Clinical Trial Services, Inc.

★ 3.7
1031 Office Park Rd #9, West Des Moines, IA 50265
(515) 223-2300
"The first time I started with Integrated Clinical Trial Services my EKG showed I had a concern. I went to Iowa Heart and was tested/treated and put …"
— kenn bekker, 5★

Heartland Medical Research

1230 8th St Ste 200, West Des Moines, IA 50265
(515) 225-6050

Des Moines University Clinic

★ 4.2
3200 Grand Ave, Des Moines, IA 50312
(515) 271-1700
"It's the osteopathic college renamed. The best part of it is the osteopathic manipulation department. I'm seeing one that can do myofascial and she's…"
— Diane Falkoski, 5★

Iowa Oncology Research Association

1221 Pleasant St #450, Des Moines, IA 50309
(515) 241-3305

The Iowa Clinic Research - West Des Moines Campus

5950 University Ave, West Des Moines, IA 50266
(515) 875-9815

OpenLoop Health

★ 4.5
317 6th Ave #400, Des Moines, IA 50309
(855) 597-1248

The Iowa Clinic Research - Ankeny Campus

1410 SW Tradition Dr, Ankeny, IA 50023
(515) 875-9815

Mission Cancer + Blood

★ 4.0 (22 reviews)
110 E Court Ave Ste. 200, Des Moines, IA 50309
(515) 282-2921
"Rating solely on disability access. This is an extremely difficult place to access, starting in the parking lot. The disabled parking is as far as p…"
— Dan Hodge, 2★

Dr. Robert R. Shreck, MD

★ 5.0 (2 reviews)
1221 Pleasant St Ste 100, Des Moines, IA 50309
(515) 282-2921
"Best doctor and friend all around Danny parnell"
— Danny Parnell, 5★

Clinical trials in Des Moines: what's recruiting

The Des Moines area currently has 220 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Des Moines, the most active research areas are:

  • Cancer & Oncology11 studies
  • Liver & Kidney6 studies
  • Diabetes & Metabolism4 studies
  • Heart & Vascular3 studies
  • Lungs & Breathing2 studies

Every listing shows the study phase, the recruiting site and its distance from Des Moines, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Des Moines

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Des Moines participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Des Moines pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Des Moines safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Des Moines, IA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Des Moines typically complete one or two studies per year.

Paid clinical trials near Des Moines

Other metros within reach

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By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Des Moines Bladder Issues Due To Spinal Cord Injury in Des Moines All conditions

More of IA

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