Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/IA/Des Moines
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Des Moines, IA

Studies commonly pay $75 to $4,500 per completed study

222 clinical trials are currently recruiting participants within 30 miles of Des Moines. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

222studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Des Moines right now

Top 25 of 222 recruiting studies, sorted by proximity — each links to its official registry page

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Wolfe Eye Clinic — West Des Moines, Iowa (5.2 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Blank Children's Hospital — Des Moines, Iowa (1.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Phase 3 Interventional 1,200 participants sought
University of Iowa Health Care. ( Site 0057) — Waukee, Iowa (14.5 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06136559)

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer Phase 3 Interventional 600 participants sought
Mission Cancer + Blood - IMMC — Des Moines, Iowa (1.9 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06793215)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Des Moines, Iowa (1.9 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Des Moines, Iowa (1.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06129864)

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism Phase 2, Phase 3 Interventional 2,800 participants sought
Iowa Diabetes and Endocrinology Research Center /ID# 256750 — West Des Moines, Iowa (5.2 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06345339)

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 189 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT02734537)

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Malignant Glioma Phase 1, Phase 2 Interventional 132 participants sought
Blank Children's Hospital — Des Moines, Iowa (1.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05099003)

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma, Stage II Pancreatic Cancer AJCC v8 Phase 3 Interventional 356 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06958328)

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Malignancy N/A Observational 240 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04242095)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
Mercy Medical Center - Des Moines — Des Moines, Iowa (1.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05561387)

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Malignant Female Reproductive System Neoplasm, Malignant Solid Neoplasm Phase 2 Interventional 70 participants sought
UI Health Care Mission Cancer and Blood - Des Moines Clinic — Des Moines, Iowa (1.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06126276)

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia Phase 3 Interventional 303 participants sought
Blank Children's Hospital — Des Moines, Iowa (1.9 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT03150693)

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Classic Follicular Lymphoma, Follicular Lymphoma With Unusual Cytological Features Phase 3 Interventional 600 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06337318)

A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma Phase 3 Interventional 700 participants sought
Mission Cancer Blood University of Iowa Health Care — Waukee, Iowa (14.5 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07518186)

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

Metastatic Salivary Gland Carcinoma, Recurrent Salivary Gland Carcinoma Phase 2 Interventional 146 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05408845)

Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital

COPD N/A Interventional 70 participants sought
Central Iowa Hospital Corp - UnityPoint Health — Des Moines, Iowa (1.9 mi) · Sponsor: Fisher and Paykel Healthcare
See eligibility & contact on ClinicalTrials.gov (NCT07222410)

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Arrhythmia, Bradycardia N/A Observational 20,000 participants sought
Research site — West Des Moines, Iowa (5.2 mi) · Sponsor: Medtronic
See eligibility & contact on ClinicalTrials.gov (NCT00271180)

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

Metabolic Dysfunction Associated Steatohepatitis Phase 3 Interventional 1,590 participants sought
Iowa Diabetes and Endocrinology Research Center — West Des Moines, Iowa (5.2 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT06632457)

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

Non-small Cell Lung Cancer Phase 3 Interventional 320 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: Canadian Cancer Trials Group
See eligibility & contact on ClinicalTrials.gov (NCT06686771)

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma Phase 3 Interventional 255 participants sought
Iowa Methodist Medical Center — Des Moines, Iowa (1.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07198074)
Actively enrolling

Studies you may be able to join near Des Moines

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Des Moines

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

ICTS Research Clinic Integrated Clinical Trial Services, Inc.

★ 3.7
1031 Office Park Rd #9, West Des Moines, IA 50265
(515) 223-2300
"The first time I started with Integrated Clinical Trial Services my EKG showed I had a concern. I went to Iowa Heart and was tested/treated and put …"
— kenn bekker, 5★

Heartland Medical Research

1230 8th St Ste 200, West Des Moines, IA 50265
(515) 225-6050

Des Moines University Clinic

★ 4.2
3200 Grand Ave, Des Moines, IA 50312
(515) 271-1700
"It's the osteopathic college renamed. The best part of it is the osteopathic manipulation department. I'm seeing one that can do myofascial and she's…"
— Diane Falkoski, 5★

Iowa Oncology Research Association

1221 Pleasant St #450, Des Moines, IA 50309
(515) 241-3305

The Iowa Clinic Research - West Des Moines Campus

5950 University Ave, West Des Moines, IA 50266
(515) 875-9815

OpenLoop Health

★ 4.5
317 6th Ave #400, Des Moines, IA 50309
(855) 597-1248

The Iowa Clinic Research - Ankeny Campus

1410 SW Tradition Dr, Ankeny, IA 50023
(515) 875-9815

Mission Cancer + Blood

★ 4.0 (22 reviews)
110 E Court Ave Ste. 200, Des Moines, IA 50309
(515) 282-2921
"Rating solely on disability access. This is an extremely difficult place to access, starting in the parking lot. The disabled parking is as far as p…"
— Dan Hodge, 2★

Dr. Robert R. Shreck, MD

★ 5.0 (2 reviews)
1221 Pleasant St Ste 100, Des Moines, IA 50309
(515) 282-2921
"Best doctor and friend all around Danny parnell"
— Danny Parnell, 5★

Clinical trials in Des Moines: what's recruiting

The Des Moines area currently has 222 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Des Moines, the most active research areas are:

  • Cancer & Oncology17 studies
  • Heart & Vascular2 studies
  • Immune & Skin1 studies
  • Lungs & Breathing1 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Des Moines, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Des Moines

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Des Moines participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Des Moines pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Des Moines safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Des Moines, IA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Des Moines typically complete one or two studies per year.

Paid clinical trials near Des Moines

Other metros within reach

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By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Des Moines Bladder Issues Due To Spinal Cord Injury in Des Moines All conditions

More of IA

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