Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/MO/Columbia
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Columbia, MO

Studies commonly pay $75 to $4,500 per completed study

264 clinical trials are currently recruiting participants within 30 miles of Columbia. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

264studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Columbia right now

Top 25 of 264 recruiting studies, sorted by proximity — each links to its official registry page

Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair

Hand Transplantation, Peripheral Nerve Injuries N/A Interventional 180 participants sought
University of Missouri — Columbia, Missouri (0.5 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT03610763)

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)

Obesity, Non-Alcoholic Fatty Liver Disease N/A Observational 60 participants sought
University of Missouri School of Medicine — Columbia, Missouri (0.5 mi) · Sponsor: Bettina Mittendorfer
See eligibility & contact on ClinicalTrials.gov (NCT06571474)

Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

Intracerebral Hemorrhage, Stroke N/A Observational 1,018 participants sought
University of Missouri — Columbia, Missouri (0.5 mi) · Sponsor: Zeenat Qureshi Stroke Institute
See eligibility & contact on ClinicalTrials.gov (NCT06402968)

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Ganglioneuroblastoma, Nodular, Neuroblastoma Phase 3 Interventional 478 participants sought
University of Missouri Children's Hospital — Columbia, Missouri (0.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06172296)

Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma Phase 3 Interventional 380 participants sought
University of Missouri Hospital /ID# 261553 — Columbia, Missouri (0.5 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06158841)

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma Phase 3 Interventional 1,450 participants sought
MU Health Care Goldschmidt Cancer Center — Jefferson City, Missouri (26.9 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT04566328)

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma Phase 3 Interventional 255 participants sought
MU Health - University Hospital/Ellis Fischel Cancer Center — Columbia, Missouri (0.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07198074)

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Moderately to Severely Active Crohns Disease Phase 3 Interventional 425 participants sought
Harry S. Truman Memorial Veterans Hospital — Columbia, Missouri (0.5 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06819891)

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

Asthma Phase 3 Interventional 724 participants sought
Teva Investigational Site 12149 — Columbia, Missouri (0.5 mi) · Sponsor: Teva Branded Pharmaceutical Products R&D LLC
See eligibility & contact on ClinicalTrials.gov (NCT06664619)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought
MU Health - University Hospital/Ellis Fischel Cancer Center — Columbia, Missouri (0.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT01810913)

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma Phase 3 Interventional 62 participants sought
University of Missouri Children's Hospital — Columbia, Missouri (0.5 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT05235165)

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma Phase 2 Interventional 80 participants sought
University of Missouri Children's Hospital — Columbia, Missouri (0.5 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT02981628)

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

Metastatic Colorectal Cancer Phase 3 Interventional 1,020 participants sought
Missouri Cancer Associates - 150518964 — Columbia, Missouri (0.5 mi) · Sponsor: EMD Serono Research & Development Institute, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07549412)

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

Non-small Cell Lung Cancer Phase 2, Phase 3 Interventional 1,260 participants sought
Missouri Cancer Associates — Columbia, Missouri (0.5 mi) · Sponsor: BioNTech SE
See eligibility & contact on ClinicalTrials.gov (NCT06712316)

Arterial Destiffening Effects of SGLT2 Inhibition in Veterans With Obesity

Obesity, Vascular Health Phase 2 Interventional 50 participants sought
Harry S. Truman Memorial, Columbia, MO — Columbia, Missouri (0.5 mi) · Sponsor: VA Office of Research and Development
See eligibility & contact on ClinicalTrials.gov (NCT06745063)

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 Phase 2 Interventional 474 participants sought
MU Health - University Hospital/Ellis Fischel Cancer Center — Columbia, Missouri (0.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06632977)

Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.

Infections, Quality of Life N/A Interventional 100 participants sought
University of Missouri — Columbia, Missouri (0.5 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT05846438)

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

Colon Cancer, Rectal Cancer Phase 2 Interventional 60 participants sought
Missouri Cancer Associates — Columbia, Missouri (0.5 mi) · Sponsor: SCRI Development Innovations, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07011576)

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

Ovarian Neoplasms, Fallopian Tube Neoplasms Phase 3 Interventional 1,630 participants sought
University of Missouri Hospital — Columbia, Missouri (0.5 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07213804)

Fabry Disease Registry & Pregnancy Sub-registry

Fabry Disease N/A Observational 9,000 participants sought
University of Missouri Health System Department of Genetics- Site Number : 840031 — Columbia, Missouri (0.5 mi) · Sponsor: Genzyme, a Sanofi Company
See eligibility & contact on ClinicalTrials.gov (NCT00196742)

Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Peripartum Cardiomyopathy, Postpartum Phase 4 Interventional 250 participants sought
Karen L Florio, MD — Columbia, Missouri (0.5 mi) · Sponsor: Dennis M. McNamara, MD, MS
See eligibility & contact on ClinicalTrials.gov (NCT05180773)
Google-rated

Top-rated research centers in Columbia

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Rural Health Research Center University of Missouri

7 Hospital Dr Ste MA306, Columbia, MO 65201

Truman VA Medical Research Foundation

★ 4.4
800 Hospital Dr, Columbia, MO 65201
(573) 814-6555
"I retired in 2013 and used Truman VamA until 2018 when I moved to Texas for a short period and switched to a different VA. The dedication of the staf…"
— Dan Stoner, 5★

Mizzou Center for Patient-Centered Outcomes Research (PCOR)

1 Hospital Dr Ste MA306, Columbia, MO 65201
(573) 882-3126

Mizzou Center for Precision Medicine

Univ Hospital, 1 Hospital Dr, Columbia, MO 65201

Cognitive Neuroscience Systems Core Facility - University of Missouri

Melvin H. Marx Bldg, 1416 Carrie Francke Dr, Columbia, MO 65203

Roy Blunt NextGen Precision Health Building

★ 4.8
1030 Hitt St, Columbia, MO 65211
(573) 882-8571
"Great customer service and team"
— Raul Vivas, 5★

MizZzou Sleep Research Lab

★ 5.0
909 Hitt St, Columbia, MO 65212
(573) 884-7428

GI Associates Research

★ 5.0
210 Portland St #104, Columbia, MO 65201
(573) 740-0800

Ellis Fischel Cancer Center

★ 4.3 (39 reviews)
1 Hospital Dr, Columbia, MO 65212
(573) 882-2100

Clinical trials in Columbia: what's recruiting

The Columbia area currently has 264 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Columbia, the most active research areas are:

  • Cancer & Oncology11 studies
  • Diabetes & Metabolism3 studies
  • Heart & Vascular3 studies
  • Liver & Kidney1 studies
  • Immune & Skin1 studies

Every listing shows the study phase, the recruiting site and its distance from Columbia, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Columbia

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Columbia participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Columbia pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Columbia safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Columbia, MO?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Columbia?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Columbia.

Paid clinical trials near Columbia

Other metros within reach

Springfield, MO157 St. Louis, MO1,481 Kansas City, MO1,000 Overland Park, KS999 Kansas City, KS1,011 Olathe, KS1,006 Springfield, IL192 Des Moines, IA226

More of MO

St. Louis1,481 Kansas City1,000 Springfield157

New paid studies open every week

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