Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/MO/Columbia
Updated October 2026 from ClinicalTrials.gov

Paid Clinical Trials in Columbia, MO

Studies commonly pay $75 to $4,500 per completed study

248 clinical trials are currently recruiting participants within 30 miles of Columbia. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

248studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Columbia right now

Top 25 of 248 recruiting studies, sorted by proximity — each links to its official registry page

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
MU Health Care Goldschmidt Cancer Center — Jefferson City, Missouri (26.9 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

Generalized Myasthenia Gravis N/A Observational 500 participants sought
Clinical Trial Site — Columbia, Missouri (0.5 mi) · Sponsor: Alexion Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04202341)

Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students

Mental Health Issue N/A Interventional 21,350 participants sought
University of Missouri — Columbia, Missouri (0.5 mi) · Sponsor: University of Virginia
See eligibility & contact on ClinicalTrials.gov (NCT06047041)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Columbia, Missouri (0.5 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06129864)

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Percutaneous Coronary Intervention, Peripheral Endovascular Intervention Phase 4 Interventional 6,000 participants sought
University of Missouri Health Care — Columbia, Missouri (0.5 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT06909565)

A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

Small Cell Lung Cancer Phase 2 Interventional 180 participants sought
Missouri Cancer Associates /ID# 278299 — Columbia, Missouri (0.5 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT07155174)

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

Non-Small Cell Lung Cancer (NSCLC) Phase 3 Interventional 750 participants sought
Missouri Cancer Associates — Columbia, Missouri (0.5 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT07361510)

Targeting Insomnia in School Aged Children With Autism Spectrum Disorder

Insomnia Chronic, Autism Spectrum Disorder N/A Interventional 180 participants sought
Thompson Center for Autism and Neurodevelopmental Disorders — Columbia, Missouri (0.5 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT04545606)

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

Limited Stage Small Cell Lung Cancer Phase 2 Interventional 250 participants sought
Missouri Cancer Associates — Columbia, Missouri (0.5 mi) · Sponsor: SCRI Development Innovations, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06773910)

Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps

Chronic Rhinosinusitis Without Nasal Polyps Phase 3 Interventional 84 participants sought
University of Missouri Medical Center — Columbia, Missouri (0.5 mi) · Sponsor: Optinose US Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06850805)

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

Sleep Architecture, Mild Traumatic Brain Injury N/A Interventional 15 participants sought
University of Missouri-Columbia — Columbia, Missouri (0.5 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT07385105)

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

Obesity or Overweight Phase 3 Interventional 2,500 participants sought
Research Site — Jefferson City, Missouri (26.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07784725)

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism Phase 2, Phase 3 Interventional 2,800 participants sought
University of Missouri Hospital /ID# 262562 — Columbia, Missouri (0.5 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06345339)

Collection and Storage of Tissue and Blood Samples From Patients With Cancer

Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm N/A Observational 5,000 participants sought
MU Health Care Goldschmidt Cancer Center — Jefferson City, Missouri (26.9 mi) · Sponsor: National Cancer Institute LAO
See eligibility & contact on ClinicalTrials.gov (NCT02474160)

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 Phase 2 Interventional 474 participants sought
MU Health - University Hospital/Ellis Fischel Cancer Center — Columbia, Missouri (0.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06632977)

Study of Fetal Health Outcomes: Working With a Missouri E-telehealth Platform (The SHOW-ME Study)

Pregnancy N/A Interventional 110 participants sought
University of Missouri — Columbia, Missouri (0.5 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT06741735)

Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

Non Small Cell Lung Cancer, Esophageal Cancer N/A Observational 320 participants sought
Harry S Truman Veterans Memorial Hospital — Columbia, Missouri (0.5 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT03551951)

Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects

Hematopoietic and Lymphoid Cell Neoplasm, Immune System Disorder N/A Observational 2,240 participants sought
MU Health Care Goldschmidt Cancer Center — Jefferson City, Missouri (26.9 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04242095)

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

Metastatic Colorectal Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8 Phase 2 Interventional 146 participants sought
MU Health - University Hospital/Ellis Fischel Cancer Center — Columbia, Missouri (0.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05673148)

Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma Phase 3 Interventional 380 participants sought
University of Missouri Hospital /ID# 261553 — Columbia, Missouri (0.5 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06158841)

Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults

Aging, Sarcopenia N/A Interventional 12 participants sought
NextGen Precision Health Building, Clinical and Translational Science Unit — Columbia, Missouri (0.5 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT06689618)
Actively enrolling

Studies you may be able to join near Columbia

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Columbia

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Rural Health Research Center University of Missouri

7 Hospital Dr Ste MA306, Columbia, MO 65201

Truman VA Medical Research Foundation

★ 4.4
800 Hospital Dr, Columbia, MO 65201
(573) 814-6555
"I retired in 2013 and used Truman VamA until 2018 when I moved to Texas for a short period and switched to a different VA. The dedication of the staf…"
— Dan Stoner, 5★

Mizzou Center for Patient-Centered Outcomes Research (PCOR)

1 Hospital Dr Ste MA306, Columbia, MO 65201
(573) 882-3126

Mizzou Center for Precision Medicine

Univ Hospital, 1 Hospital Dr, Columbia, MO 65201

Cognitive Neuroscience Systems Core Facility - University of Missouri

Melvin H. Marx Bldg, 1416 Carrie Francke Dr, Columbia, MO 65203

Roy Blunt NextGen Precision Health Building

★ 4.8
1030 Hitt St, Columbia, MO 65211
(573) 882-8571
"Great customer service and team"
— Raul Vivas, 5★

MizZzou Sleep Research Lab

★ 5.0
909 Hitt St, Columbia, MO 65212
(573) 884-7428

GI Associates Research

★ 5.0
210 Portland St #104, Columbia, MO 65201
(573) 740-0800

Ellis Fischel Cancer Center

★ 4.3 (39 reviews)
1 Hospital Dr, Columbia, MO 65212
(573) 882-2100

Clinical trials in Columbia: what's recruiting

The Columbia area currently has 248 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Columbia, the most active research areas are:

  • Cancer & Oncology9 studies
  • Heart & Vascular2 studies
  • Diabetes & Metabolism1 studies
  • Lungs & Breathing1 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from Columbia, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Columbia

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Columbia participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Columbia pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Columbia safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Columbia, MO?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Columbia?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Columbia.

Paid clinical trials near Columbia

Other metros within reach

Springfield, MO153 St. Louis, MO1,513 Kansas City, MO1,035 Overland Park, KS1,034 Kansas City, KS1,046 Olathe, KS1,042 Springfield, IL184 Des Moines, IA226

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Columbia Bladder Issues Due To Spinal Cord Injury in Columbia All conditions

More of MO

St. Louis1,513 Kansas City1,035 Springfield153

New paid studies open every week

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