Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/MO/Columbia
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Columbia, MO

Studies commonly pay $75 to $4,500 per completed study

256 clinical trials are currently recruiting participants within 30 miles of Columbia. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

256studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Columbia right now

Top 25 of 256 recruiting studies, sorted by proximity — each links to its official registry page

Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair

Hand Transplantation, Peripheral Nerve Injuries N/A Interventional 180 participants sought
University of Missouri — Columbia, Missouri (0.5 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT03610763)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
Capital Region Southwest Campus — Jefferson City, Missouri (26.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05561387)

Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students

Mental Health Issue N/A Interventional 21,350 participants sought
University of Missouri — Columbia, Missouri (0.5 mi) · Sponsor: University of Virginia
See eligibility & contact on ClinicalTrials.gov (NCT06047041)

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Percutaneous Coronary Intervention, Peripheral Endovascular Intervention Phase 4 Interventional 6,000 participants sought
University of Missouri Health Care — Columbia, Missouri (0.5 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT06909565)

uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

Urothelial Carcinoma, Urothelial Carcinoma Recurrent N/A Observational 400 participants sought
University of Missouri — Columbia, Missouri (0.5 mi) · Sponsor: UroGen Pharma Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT05874921)

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Ganglioneuroblastoma, Nodular, Neuroblastoma Phase 3 Interventional 478 participants sought
University of Missouri Children's Hospital — Columbia, Missouri (0.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06172296)

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

Locally Advanced Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8 Phase 3 Interventional 474 participants sought
MU Health - University Hospital/Ellis Fischel Cancer Center — Columbia, Missouri (0.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05624996)

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

Limited Stage Small Cell Lung Cancer Phase 2 Interventional 250 participants sought
Missouri Cancer Associates — Columbia, Missouri (0.5 mi) · Sponsor: SCRI Development Innovations, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06773910)

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

Sleep Architecture, Mild Traumatic Brain Injury N/A Interventional 15 participants sought
University of Missouri-Columbia — Columbia, Missouri (0.5 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT07385105)

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 Phase 3 Interventional 1,875 participants sought
University of Missouri Children's Hospital — Columbia, Missouri (0.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05675410)

Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma Phase 3 Interventional 380 participants sought
University of Missouri Hospital /ID# 261553 — Columbia, Missouri (0.5 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06158841)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

Muscle Invasive Bladder Urothelial Carcinoma, Stage II Bladder Cancer AJCC v8 Phase 3 Interventional 486 participants sought
MU Health - University Hospital/Ellis Fischel Cancer Center — Columbia, Missouri (0.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT07097142)

Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy

Lumbar Disc Herniation Phase 4 Interventional 200 participants sought
Missouri Orthopaedic Institute — Columbia, Missouri (0.5 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT04182997)

A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

HIV Infections Phase 2 Interventional 186 participants sought
GSK Investigational Site — Columbia, Missouri (0.5 mi) · Sponsor: ViiV Healthcare
See eligibility & contact on ClinicalTrials.gov (NCT07202546)

A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively

Schizophrenia, Autism-Related Irritability Phase 3 Interventional 400 participants sought
Local Institution - 0142 — Columbia, Missouri (0.5 mi) · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See eligibility & contact on ClinicalTrials.gov (NCT07424404)

Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

Non Small Cell Lung Cancer, Esophageal Cancer N/A Observational 320 participants sought
Harry S Truman Veterans Memorial Hospital — Columbia, Missouri (0.5 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT03551951)

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

High Grade Osteosarcoma, Localized Osteosarcoma Phase 2, Phase 3 Interventional 1,122 participants sought
University of Missouri Children's Hospital — Columbia, Missouri (0.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05691478)

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Cardiovascular Risk, Acute Myocardial Infarction (AMI) Phase 3 Interventional 10,000 participants sought
Missouri Cardiovascular Specialist — Columbia, Missouri (0.5 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT06118281)

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 189 participants sought
MU Health Care Goldschmidt Cancer Center — Jefferson City, Missouri (26.9 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT02734537)

7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)

Small-cell Lung Cancer, Brain Metastases N/A Observational 20 participants sought
University of Missouri — Columbia, Missouri (0.5 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT07175077)

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

Urothelial Cancer, Urinary Bladder Neoplasms Phase 3 Interventional 390 participants sought
Missouri Cancer Associates — Columbia, Missouri (0.5 mi) · Sponsor: Astellas Pharma Global Development, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07566156)

S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8, Estrogen Receptor Positive N/A Interventional 739 participants sought
University of Missouri - Ellis Fischel — Columbia, Missouri (0.5 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03723928)
Actively enrolling

Studies you may be able to join near Columbia

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Columbia

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Rural Health Research Center University of Missouri

7 Hospital Dr Ste MA306, Columbia, MO 65201

Truman VA Medical Research Foundation

★ 4.4
800 Hospital Dr, Columbia, MO 65201
(573) 814-6555
"I retired in 2013 and used Truman VamA until 2018 when I moved to Texas for a short period and switched to a different VA. The dedication of the staf…"
— Dan Stoner, 5★

Mizzou Center for Patient-Centered Outcomes Research (PCOR)

1 Hospital Dr Ste MA306, Columbia, MO 65201
(573) 882-3126

Mizzou Center for Precision Medicine

Univ Hospital, 1 Hospital Dr, Columbia, MO 65201

Cognitive Neuroscience Systems Core Facility - University of Missouri

Melvin H. Marx Bldg, 1416 Carrie Francke Dr, Columbia, MO 65203

Roy Blunt NextGen Precision Health Building

★ 4.8
1030 Hitt St, Columbia, MO 65211
(573) 882-8571
"Great customer service and team"
— Raul Vivas, 5★

MizZzou Sleep Research Lab

★ 5.0
909 Hitt St, Columbia, MO 65212
(573) 884-7428

GI Associates Research

★ 5.0
210 Portland St #104, Columbia, MO 65201
(573) 740-0800

Ellis Fischel Cancer Center

★ 4.3 (39 reviews)
1 Hospital Dr, Columbia, MO 65212
(573) 882-2100

Clinical trials in Columbia: what's recruiting

The Columbia area currently has 256 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Columbia, the most active research areas are:

  • Cancer & Oncology14 studies
  • Heart & Vascular2 studies
  • Liver & Kidney2 studies
  • Brain & Mental Health1 studies

Every listing shows the study phase, the recruiting site and its distance from Columbia, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Columbia

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Columbia participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Columbia pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Columbia safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Columbia, MO?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Columbia?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Columbia.

Paid clinical trials near Columbia

Other metros within reach

Springfield, MO155 St. Louis, MO1,476 Kansas City, MO1,024 Overland Park, KS1,023 Kansas City, KS1,035 Olathe, KS1,030 Springfield, IL192 Des Moines, IA221

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Columbia Bladder Issues Due To Spinal Cord Injury in Columbia All conditions

More of MO

St. Louis1,476 Kansas City1,024 Springfield155

New paid studies open every week

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