Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CA/Ontario
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Ontario, CA

Studies commonly pay $75 to $4,500 per completed study

1,702 clinical trials are currently recruiting participants within 30 miles of Ontario. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,702studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Ontario right now

Top 25 of 1,702 recruiting studies, sorted by proximity — each links to its official registry page

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Loma Linda University Medical Center — Loma Linda, California (19.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
City of Hope National Medical Center — Duarte, California (22.3 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)

Primary Membranous Nephropathy Phase 2 Interventional 30 participants sought
Research Site — Loma Linda, California (19.8 mi) · Sponsor: Alexion Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07157787)

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
Loma Linda University Medical Center — Loma Linda, California (19.8 mi) · Sponsor: Medtronic MiniMed, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07228117)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Orange County Retina Med Group — Santa Ana, California (25.2 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)

Limb Girdle Muscular Dystrophy, Limb-Girdle Muscular Dystrophy Type 2 Phase 1, Phase 2 Interventional 10 participants sought
University of California - Irvine — Irvine, California (28.4 mi) · Sponsor: AskBio Inc
See eligibility & contact on ClinicalTrials.gov (NCT05230459)

A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors

Advanced Cancer, Solid Tumor Phase 1 Interventional 26 participants sought
City of Hope National Medical Center — Duarte, California (22.3 mi) · Sponsor: Proviva Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06190886)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Duarte, California (22.3 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Carcinoma, Non-Small-Cell Lung Phase 1, Phase 2 Interventional 450 participants sought
City of Hope ( Site 0014) — Duarte, California (22.3 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT04165070)

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Phase 2 Interventional 120 participants sought
University of California Irvine — Orange, California (22.4 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06465329)

A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors

MTAP-deleted Solid Tumors Phase 1, Phase 2 Interventional 450 participants sought
City of Hope - Duarte Cancer Center — Duarte, California (22.3 mi) · Sponsor: Bayer
See eligibility & contact on ClinicalTrials.gov (NCT06914128)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Kaiser Permanente-Ontario — Ontario, California (3.0 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis Phase 2 Interventional 168 participants sought
North America Research Institute — San Dimas, California (12.4 mi) · Sponsor: R1 Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06712654)

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Percutaneous Coronary Intervention, Peripheral Endovascular Intervention Phase 4 Interventional 6,000 participants sought
Riverside Community Hospital — Riverside, California (13.4 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT06909565)

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Chronic Migraine Phase 3 Interventional 420 participants sought
Advanced Research Center /ID# 270257 — Anaheim, California (22.6 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06810505)

Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis

Lewy Body Dementia Psychosis Phase 2 Interventional 180 participants sought
ATP Clinical Research Inc. — Irvine, California (28.4 mi) · Sponsor: ACADIA Pharmaceuticals Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07029581)

Evaluating the Impact of Training for IHSS Workers

Home Care for Elderly or Disabled Individuals N/A Interventional 2,500 participants sought
San Bernardino County — San Bernardino, California (18.7 mi) · Sponsor: Abdul Latif Jameel Poverty Action Lab
See eligibility & contact on ClinicalTrials.gov (NCT06205433)

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

Lymphoma, B-Cell, Lymphoma, Non-Hodgkin (NHL) Phase 1 Interventional 106 participants sought
City of Hope — Duarte, California (22.3 mi) · Sponsor: Umoja Biopharma
See eligibility & contact on ClinicalTrials.gov (NCT06528301)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
University of California, Irvine (UCI) Health - UC Irvine Medical Center — Orange, California (22.4 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia, Recurrent Adult Acute Myeloid Leukemia Phase 1 Interventional 27 participants sought
City of Hope Medical Center — Duarte, California (22.3 mi) · Sponsor: City of Hope Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT05672147)

Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2

Intracerebral Hemorrhage Phase 3 Interventional 350 participants sought
Kaiser Permanente Fontana Medical Center — Fontana, California (10.5 mi) · Sponsor: Joseph Broderick, MD
See eligibility & contact on ClinicalTrials.gov (NCT07227246)
Actively enrolling

Studies you may be able to join near Ontario

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Ontario

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Catalina Research Institute

★ 4.5
9525 Monte Vista Ave Ste 200, Montclair, CA 91763
(909) 590-8409
"Hi my name is Lionel Thomas I value innovation, data, and helping people, participating in a clinical trial with Catalina Research Institute has been…"
— Lionel Thomas, 5★

Brio Clinical

★ 3.6
1910 S Archibald Ave # U, Ontario, CA 91761
(951) 465-3500
"It seems like the staffing team doesn't really know how to properly update or communicate regarding referrals—or perhaps they just don't prioritize t…"
— Dezza Barredo-Alcala, 1★

Empire Clinical Research

★ 4.2 (39 reviews)
2740 N Garey Ave #203, Pomona, CA 91767
(909) 981-5321
"Absolutely awful.. the staff is very good, kind, but they waste your time and do not pay"
— Jeffrey Marquez, 1★

Dream Team Clinical Research

★ 5.0
1800 N Orange Grove Ave, Pomona, CA 91767
(714) 780-0076

WesternU Health Center for Clinical & Translational Research

★ 5.0
795 E 2nd St Second Floor, Suite 2003, Pomona, CA 91766
(909) 469-8626

Critical Care Research Inc

★ 5.0
10743 Civic Center Dr, Rancho Cucamonga, CA 91730
(909) 987-3883
"Now look at my problem<br>Hello I am interested in attending the Friday May 29 @ 1pm information session @ University of South Alabama. My Bachelor o…"
— Kel Moy, 5★

Prospective Research Innovations Inc.

★ 5.0
8577 Haven Ave Suite 301, 8577 Haven Ave #301, Rancho Cucamonga, CA 91730
(626) 559-2770
"I've had an amazing experience with Prospective Research. The staff were really nice and caring, and the facilities were top-notch. Everything was re…"
— Ajwa Khalil, 5★

Infinity Clinical Research

★ 3.5
1901 Town and Country Dr Ste 104, Norco, CA 92860
(714) 252-6689
"I just completed a year-long clinical research trial and had an excellent experience! The staff at the Norco location were always professional, knowl…"
— Jonnine Eras, 5★

National Institute of Clinical Research - Pomona

★ 5.0
630 N Park Ave, Pomona, CA 91768
(909) 766-8042
"Awesome clinical trial office the staff are incredible courteous and professional lots of trials to participate in or be on the list. All in all tops…"
— James Marquez, 5★

Clinical trials in Ontario: what's recruiting

The Ontario area currently has 1,702 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Ontario, the most active research areas are:

  • Cancer & Oncology13 studies
  • Heart & Vascular3 studies
  • Diabetes & Metabolism1 studies
  • Liver & Kidney1 studies
  • Brain & Mental Health1 studies

Every listing shows the study phase, the recruiting site and its distance from Ontario, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Ontario

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Ontario participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in Ontario safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Ontario, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Ontario?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Ontario typically complete one or two studies per year.

Paid clinical trials near Ontario

Other metros within reach

Rancho Cucamonga, CA1,472 Pomona, CA3,123 Fontana, CA965 Corona, CA1,565 Riverside, CA936 Anaheim, CA3,164 San Bernardino, CA460 Fullerton, CA3,230

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Ontario Bladder Issues Due To Spinal Cord Injury in Ontario All conditions

More of CA

Long Beach3,348 Torrance3,239 Fullerton3,230 Anaheim3,164 Garden Grove3,162 Pomona3,123 Glendale2,948 Los Angeles2,936 Huntington Beach2,847 Santa Clarita2,389 Hayward2,266 Oakland2,257

New paid studies open every week

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