Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CA/Rancho Cucamonga
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Rancho Cucamonga, CA

Studies commonly pay $75 to $4,500 per completed study

1,489 clinical trials are currently recruiting participants within 30 miles of Rancho Cucamonga. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,489studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Rancho Cucamonga right now

Top 25 of 1,489 recruiting studies, sorted by proximity — each links to its official registry page

Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma

NK-Cell Lymphoma, NK-Cell Leukemia EARLY/Phase 1 Interventional 40 participants sought
Children's Hospital Orange County — Orange, California (28.5 mi) · Sponsor: New York Medical College
See eligibility & contact on ClinicalTrials.gov (NCT03719105)

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A

Von Willebrand Disease, Type 3, Concomitant VWD and Hemophilia Phase 1 Interventional 40 participants sought
The Center for Comprehensive Care and Diagnosis of Inherited Blood Disorders (CIBD) — Orange, California (28.5 mi) · Sponsor: Bleeding and Clotting Disorders Institute Peoria, Illinois
See eligibility & contact on ClinicalTrials.gov (NCT05500807)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Loma Linda University Medical Center — Loma Linda, California (18.3 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
City of Hope Comprehensive Cancer Center ( Site 0191) — Duarte, California (23.5 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
City of Hope National Medical Center — Duarte, California (23.5 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

Rheumatoid Arthritis, Systemic Lupus Erythematosus Phase 1 Interventional 48 participants sought
Research Site — Fullerton, California (27.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07201558)

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
Loma Linda University Medical Center — Loma Linda, California (18.3 mi) · Sponsor: Medtronic MiniMed, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07228117)

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought
Win Retina — Arcadia, California (26.8 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07553429)

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Carcinoma, Non-Small-Cell Lung Phase 1, Phase 2 Interventional 450 participants sought
City of Hope ( Site 0014) — Duarte, California (23.5 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT04165070)

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, H3 K27M-Mutant Phase 1 Interventional 36 participants sought
Children's Health Orange County (CHOC) — Orange, California (28.5 mi) · Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago
See eligibility & contact on ClinicalTrials.gov (NCT04943848)

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma Phase 1 Interventional 694 participants sought
City of Hope National Medical Center /ID# 276272 — Duarte, California (23.5 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT05005403)

Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum Disorder

Neuromyelitis Optica Spectrum Disorder Phase 2 Interventional 15 participants sought
Loma Linda University Children's Hospital - PIN — Loma Linda, California (18.3 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT05549258)

Shorter Versus Extended Course of Antibiotic Therapy for Necrotizing Soft Tissue Infections

Necrotizing Soft Tissue Infection N/A Observational 50 participants sought
University of California Irvine Medical Center — Orange, California (28.5 mi) · Sponsor: University of California, Irvine
See eligibility & contact on ClinicalTrials.gov (NCT06002607)

A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors

Advanced Cancer, Solid Tumor Phase 1 Interventional 26 participants sought
City of Hope National Medical Center — Duarte, California (23.5 mi) · Sponsor: Proviva Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06190886)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Duarte, California (23.5 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma

B-Cell Non-Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma Phase 1 Interventional 15 participants sought
City of Hope Medical Center — Duarte, California (23.5 mi) · Sponsor: City of Hope Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT05432635)

Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD

Age-Related Macular Degeneration, Geographic Atrophy N/A Interventional 125 participants sought
Loma Linda University — Loma Linda, California (18.3 mi) · Sponsor: VisionCare, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05438732)

First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

Advanced Metastatic Castration-resistant Prostate Cancer, Prostate Specific Membrane Antigen (PSMA) Expression Phase 1 Interventional 198 participants sought
City of Hope - Duarte Cancer Center — Duarte, California (23.5 mi) · Sponsor: Bayer
See eligibility & contact on ClinicalTrials.gov (NCT06217822)

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Phase 1 Interventional 15 participants sought
City of Hope Medical Center — Duarte, California (23.5 mi) · Sponsor: City of Hope Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT06287944)

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Phase 2 Interventional 120 participants sought
University of California Irvine — Orange, California (28.5 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06465329)

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

Lymphoma, B-Cell, Lymphoma, Non-Hodgkin (NHL) Phase 1 Interventional 106 participants sought
City of Hope — Duarte, California (23.5 mi) · Sponsor: Umoja Biopharma
See eligibility & contact on ClinicalTrials.gov (NCT06528301)

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis Phase 2 Interventional 168 participants sought
North America Research Institute — San Dimas, California (13.8 mi) · Sponsor: R1 Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06712654)

Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

Breast Carcinoma, Chemotherapy-Induced Peripheral Neuropathy Phase 2 Interventional 120 participants sought
City of Hope Medical Center — Duarte, California (23.5 mi) · Sponsor: City of Hope Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT06731894)

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

Urothelial Cancer, Bladder Cancer Phase 2, Phase 3 Interventional 630 participants sought
Research Site — Fullerton, California (27.0 mi) · Sponsor: Daiichi Sankyo
See eligibility & contact on ClinicalTrials.gov (NCT07129993)
Actively enrolling

Studies you may be able to join near Rancho Cucamonga

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Rancho Cucamonga

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Critical Care Research Inc

★ 5.0
10743 Civic Center Dr, Rancho Cucamonga, CA 91730
(909) 987-3883
"Now look at my problem<br>Hello I am interested in attending the Friday May 29 @ 1pm information session @ University of South Alabama. My Bachelor o…"
— Kel Moy, 5★

Prospective Research Innovations Inc.

★ 5.0
8577 Haven Ave Suite 301, 8577 Haven Ave #301, Rancho Cucamonga, CA 91730
(626) 559-2770
"I've had an amazing experience with Prospective Research. The staff were really nice and caring, and the facilities were top-notch. Everything was re…"
— Ajwa Khalil, 5★

Catalina Research Institute

★ 4.5
9525 Monte Vista Ave Ste 200, Montclair, CA 91763
(909) 590-8409
"Hi my name is Lionel Thomas I value innovation, data, and helping people, participating in a clinical trial with Catalina Research Institute has been…"
— Lionel Thomas, 5★

Empire Clinical Research

★ 4.2 (39 reviews)
2740 N Garey Ave #203, Pomona, CA 91767
(909) 981-5321
"Absolutely awful.. the staff is very good, kind, but they waste your time and do not pay"
— Jeffrey Marquez, 1★

Dream Team Clinical Research

★ 5.0
1800 N Orange Grove Ave, Pomona, CA 91767
(714) 780-0076

WesternU Health Center for Clinical & Translational Research

★ 5.0
795 E 2nd St Second Floor, Suite 2003, Pomona, CA 91766
(909) 469-8626

Pacific Clinical Research

★ 1.0
1317 W Foothill Blvd, Upland, CA 91786
(909) 920-3000
"I used to come here many years ago and they helped me so much with my depression. Back then, they had so many wonderful people that were professional…"
— Kelly Ayers, 1★

National Institute of Clinical Research - Pomona

★ 5.0
630 N Park Ave, Pomona, CA 91768
(909) 766-8042
"Awesome clinical trial office the staff are incredible courteous and professional lots of trials to participate in or be on the list. All in all tops…"
— James Marquez, 5★

CenExel Riverside CA

★ 4.7
5700 Division St, Riverside, CA 92506
(866) 478-8391
"You have to experience it for yourself.."
— Jarad Racine, 5★

Clinical trials in Rancho Cucamonga: what's recruiting

The Rancho Cucamonga area currently has 1,489 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Rancho Cucamonga, the most active research areas are:

  • Cancer & Oncology17 studies
  • Diabetes & Metabolism2 studies
  • Immune & Skin1 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from Rancho Cucamonga, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Rancho Cucamonga

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Rancho Cucamonga participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in Rancho Cucamonga safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Rancho Cucamonga, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Rancho Cucamonga?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Rancho Cucamonga?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Rancho Cucamonga.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Rancho Cucamonga typically complete one or two studies per year.

Paid clinical trials near Rancho Cucamonga

Other metros within reach

Ontario, CA1,726 Fontana, CA982 Pomona, CA3,148 Riverside, CA955 Corona, CA1,582 San Bernardino, CA465 Anaheim, CA3,193 Moreno Valley, CA436

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Rancho Cucamonga Bladder Issues Due To Spinal Cord Injury in Rancho Cucamonga All conditions

More of CA

Long Beach3,366 Torrance3,258 Fullerton3,251 Anaheim3,193 Garden Grove3,186 Pomona3,148 Glendale2,964 Los Angeles2,949 Huntington Beach2,867 Santa Clarita2,384 Hayward2,257 Oakland2,248

New paid studies open every week

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