Live from the NIH registry
Studies recruiting near Rancho Cucamonga right now
Top 25 of 1,472 recruiting studies, sorted by proximity — each links to its official registry page
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
B Acute Lymphoblastic Leukemia
Phase 2
Interventional 222 participants sought
Loma Linda University Medical Center — Loma Linda, California (18.3 mi)
· Sponsor: National Cancer Institute (NCI)
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
PIK3CA Mutation, HER2- Negative Breast Cancer
Phase 3
Interventional 540 participants sought
City of Hope National Medical Center — Duarte, California (23.5 mi)
· Sponsor: Relay Therapeutics, Inc.
Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)
Primary Membranous Nephropathy
Phase 2
Interventional 30 participants sought
Research Site — Loma Linda, California (18.3 mi)
· Sponsor: Alexion Pharmaceuticals, Inc.
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
N/A
Interventional 400 participants sought
Loma Linda University Medical Center — Loma Linda, California (18.3 mi)
· Sponsor: Medtronic MiniMed, Inc.
Effect of Electro-Acupuncture on Blood Pressure
Hypertension
N/A
Interventional 160 participants sought
UCIMedical Center — Orange, California (28.5 mi)
· Sponsor: University of California, Irvine
KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)
Carcinoma, Non-Small-Cell Lung
Phase 1, Phase 2
Interventional 450 participants sought
City of Hope ( Site 0014) — Duarte, California (23.5 mi)
· Sponsor: Merck Sharp & Dohme LLC
A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors
Advanced Cancer, Solid Tumor
Phase 1
Interventional 26 participants sought
City of Hope National Medical Center — Duarte, California (23.5 mi)
· Sponsor: Proviva Therapeutics, Inc.
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
Endometrial Cancer
Phase 3
Interventional 600 participants sought
Research Site — Duarte, California (23.5 mi)
· Sponsor: AstraZeneca
A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)
Non-Small Cell Lung Cancer
Phase 2
Interventional 120 participants sought
University of California Irvine — Orange, California (28.5 mi)
· Sponsor: Regeneron Pharmaceuticals
A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies
Lymphoma, B-Cell, Lymphoma, Non-Hodgkin (NHL)
Phase 1
Interventional 106 participants sought
City of Hope — Duarte, California (23.5 mi)
· Sponsor: Umoja Biopharma
A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia
Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis
Phase 2
Interventional 168 participants sought
North America Research Institute — San Dimas, California (13.8 mi)
· Sponsor: R1 Therapeutics
A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors
MTAP-deleted Solid Tumors
Phase 1, Phase 2
Interventional 450 participants sought
City of Hope - Duarte Cancer Center — Duarte, California (23.5 mi)
· Sponsor: Bayer
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Previously Treated Non-Small Cell Lung Cancer
Phase 2, Phase 3
Interventional 10,000 participants sought
City of Hope Upland — Upland, California (5.0 mi)
· Sponsor: SWOG Cancer Research Network
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
Percutaneous Coronary Intervention, Peripheral Endovascular Intervention
Phase 4
Interventional 6,000 participants sought
Riverside Community Hospital — Riverside, California (15.3 mi)
· Sponsor: Duke University
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
Carcinoma, Transitional Cell, Urinary Bladder Neoplasms
Phase 3
Interventional 450 participants sought
University of California, Irvine (UCI) Health - UC Irvine Medical Center — Orange, California (28.5 mi)
· Sponsor: Eli Lilly and Company
A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)
Renal Cell Carcinoma
Phase 3
Interventional 904 participants sought
Providence Medical Foundation ( Site 0141) — Fullerton, California (27.0 mi)
· Sponsor: Merck Sharp & Dohme LLC
A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies
Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)
Phase 1
Interventional 248 participants sought
City of Hope — Duarte, California (23.5 mi)
· Sponsor: Nurix Therapeutics, Inc.
A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years
Chronic Migraine
Phase 3
Interventional 420 participants sought
Advanced Research Center /ID# 270257 — Anaheim, California (28.2 mi)
· Sponsor: AbbVie
Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy
Cancer, Neoplasms
N/A
Interventional 35 participants sought
UCI Health - Yorba Linda — Yorba Linda, California (21.6 mi)
· Sponsor: University of California, Irvine
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2
Intracerebral Hemorrhage
Phase 3
Interventional 350 participants sought
Kaiser Permanente Fontana Medical Center — Fontana, California (7.9 mi)
· Sponsor: Joseph Broderick, MD
Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN
IC-MPGN
Phase 3
Interventional 106 participants sought
Univ Cali Irvine ALS Neuromuscular — Orange, California (28.5 mi)
· Sponsor: Novartis Pharmaceuticals
Evaluating the Impact of Training for IHSS Workers
Home Care for Elderly or Disabled Individuals
N/A
Interventional 2,500 participants sought
San Bernardino County — San Bernardino, California (15.9 mi)
· Sponsor: Abdul Latif Jameel Poverty Action Lab
E-Mindfulness Approaches for Living After Breast Cancer
Breast Cancer, Depression
Phase 3
Interventional 402 participants sought
Kaiser Permanente-Ontario — Ontario, California (6.4 mi)
· Sponsor: NRG Oncology
Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial
Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma
Phase 3
Interventional 1,524 participants sought
UC Irvine Health/Chao Family Comprehensive Cancer Center — Orange, California (28.5 mi)
· Sponsor: Alliance for Clinical Trials in Oncology
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
Pulmonary Invasive Fungal Infections, Pulmonary Invasive Aspergillosis
N/A
Observational 400 participants sought
Children's Hospital of Orange County — Orange, California (28.5 mi)
· Sponsor: Arkansas Children's Hospital Research Institute