Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CA/San Diego
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in San Diego, CA

Studies commonly pay $75 to $4,500 per completed study

1,336 clinical trials are currently recruiting participants within 30 miles of San Diego. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,336studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near San Diego right now

Top 25 of 1,336 recruiting studies, sorted by proximity — each links to its official registry page

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Rady Children's Hospital - San Diego — San Diego, California (8.4 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)

Locally Advanced Solid Tumor, Metastatic Solid Tumor Phase 1 Interventional 30 participants sought
University of California San Diego — San Diego, California (8.4 mi) · Sponsor: Acepodia Biotech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06415487)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
University of California San Diego Moores Cancer Center — San Diego, California (8.4 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
Rady Children's Hospital - San Diego — San Diego, California (8.4 mi) · Sponsor: Medtronic MiniMed, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07228117)

Targeting Minority Stressors to Improve Eating Disorder Symptoms in Sexual Minority Individuals With Eating Disorders

Eating Disorders, Sexual Minorities Phase 1 Interventional 30 participants sought
San Diego State University — San Diego, California (8.4 mi) · Sponsor: Auburn University
See eligibility & contact on ClinicalTrials.gov (NCT06565637)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — La Jolla, California (8.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)

Primary Membranous Nephropathy Phase 2 Interventional 30 participants sought
Research Site — San Diego, California (8.4 mi) · Sponsor: Alexion Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07157787)

Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis

Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps N/A Interventional 300 participants sought
SENTA Clinica — San Diego, California (8.4 mi) · Sponsor: Airiver Medical, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07290140)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Kaiser Permanente-San Diego Mission — San Diego, California (8.4 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

Melanoma Stage III, Melanoma Stage IV Phase 2 Interventional 25 participants sought
UC San Diego Moores Cancer Center — La Jolla, California (8.9 mi) · Sponsor: University of California, San Francisco
See eligibility & contact on ClinicalTrials.gov (NCT04598009)

Automated Insulin for Management of Intrapartum Glycemia

Type 1 Diabetes (T1D), Pregnancy N/A Interventional 150 participants sought
University of California, San Diego — San Diego, California (8.4 mi) · Sponsor: University of California, San Francisco
See eligibility & contact on ClinicalTrials.gov (NCT06883344)

Androgen Effects on the Reproductive Neuroendocrine Axis, 2025 Version

Transgenderism, Reproductive Issues Phase 4 Interventional 80 participants sought
University of California, San Diego — San Diego, California (8.4 mi) · Sponsor: University of California, San Diego
See eligibility & contact on ClinicalTrials.gov (NCT07092527)

A Study to Investigate the Safety and Efficacy of MEDI0618 Compared to Placebo in Adult Participants With Episodic Migraine

Migraine Phase 2 Interventional 488 participants sought
The Neurology Center of Southern California - Carlsbad Office — La Jolla, California (8.9 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06602479)

First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours

Hepatocellular Carcinoma Phase 1, Phase 2 Interventional 304 participants sought
Research Site — La Jolla, California (8.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06795022)

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes N/A Observational 200 participants sought
University of California San Diego — San Diego, California (8.4 mi) · Sponsor: Jaeb Center for Health Research
See eligibility & contact on ClinicalTrials.gov (NCT06837181)

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis Phase 2 Interventional 168 participants sought
California Institute of Renal Research — Chula Vista, California (13.4 mi) · Sponsor: R1 Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06712654)

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Chronic Migraine Phase 3 Interventional 420 participants sought
Excell Research /ID# 270258 — Oceanside, California (29.3 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06810505)

Study Evaluating the Safety and Efficacy of Neffy or Intramuscular Adrenalin in Patients With Allergic Reactions After Oral Food Challenge or Allergen Immunotherapy

Allergic Reactions Phase 4 Interventional 600 participants sought
Orso Health, Inc. — La Jolla, California (8.9 mi) · Sponsor: ARS Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06834165)

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

Bladder Carcinoma, Ureter Carcinoma N/A Observational 2,020 participants sought
University of California, San Diego — La Jolla, California (8.9 mi) · Sponsor: Guardant Health, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05059444)

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Ulcerative Colitis, Crohn's Disease Phase 3 Interventional 240 participants sought
Rady Children's Hospital - San Diego - PIN — San Diego, California (8.4 mi) · Sponsor: Takeda
See eligibility & contact on ClinicalTrials.gov (NCT05442567)

Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer Survivors

Breast Cancer Survivor Phase 2 Interventional 200 participants sought
University of California San Diego (Data collection and Data analysis) — San Diego, California (8.4 mi) · Sponsor: Memorial Sloan Kettering Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT06728579)
Actively enrolling

Studies you may be able to join near San Diego

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for severe chronic itching

Enrolling adults aged 18 to 90 who have had chronic itching for six months or longer. Not open to itching caused by atopic dermatitis, psoriasis, chronic kidney disease, notalgia paresthetica or medication, nor to people with an autoimmune condition such as lupus, Crohn's disease, ulcerative colitis or rheumatoid arthritis.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in San Diego

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Artemis Institute for Clinical Research

★ 4.8
3870 Murphy Canyon Rd Ste 200, San Diego, CA 92123
(858) 278-3647
"The Staff is amazing!! Every person I have worked with there has been very professional and helpful. The location is great. I highly recommend them."
— William Rodriguez, 5★

California Research Foundation

★ 4.3
9444 Farnham St #200, San Diego, CA 92123
(619) 291-2321
"This is a very clean, quiet, and professional environment. I have done clinical trials in the past and feel like I am just a number. From the time I …"
— John McMann, 5★

M3 Wake Research San Diego - Convoy

★ 4.1
3709 Convoy St, San Diego, CA 92111
(858) 505-8672
"They were very professional. Answered all my questions; some of a delicate nature. The doctor was very helpful. I would recommend this study for wom…"
— Rose Garay, 5★

Paradigm Clinical Research

★ 4.4
9095 Rio San Diego Dr Ste 400, San Diego, CA 92108
(858) 274-4226
"Best clinical research trial I’ve joined so far. Staff is really friendly and professional. Was paid right away after every visit. Very well run plac…"
— Khem See, 5★

Velocity Clinical Research

★ 3.1
8881 Fletcher Pkwy Ste 300, La Mesa, CA 91942
(619) 567-1550
"I am disappointed with my experience at Velocity Research’s La Mesa location. The information on the company’s website appears to be incorrect or mis…"
— Geo, 1★

University Clinical Trials

7695 Cardinal Ct #200, San Diego, CA 92123
(858) 278-8470

Synergy Research Centers

★ 3.9
7922 Palm St, Lemon Grove, CA 91945
(619) 303-6130
"I love the staff they are super nice...."
— Jasmin Mendez, 5★

Apex Clinical Research

★ 5.0
5555 Reservoir Dr #209, San Diego, CA 92120
(619) 582-5564
"The staff are very knowledgeable and friendly i would definitely recommend"
— Travis Barnes, 5★

Horizon Clinical Research

★ 4.6
Suite 259, 5565 Grossmont Center Dr Bldg 3, La Mesa, CA 91942
(619) 456-6012
"The research team, from support staff to doctors, are incredibly kind and helpful. It is clear that they are driving to the solution and a better qua…"
— John C Edmonston, 5★

Clinical trials in San Diego: what's recruiting

The San Diego area currently has 1,336 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to San Diego, the most active research areas are:

  • Cancer & Oncology11 studies
  • Liver & Kidney5 studies
  • Diabetes & Metabolism3 studies
  • Heart & Vascular1 studies
  • Immune & Skin1 studies

Every listing shows the study phase, the recruiting site and its distance from San Diego, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in San Diego

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

San Diego participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in San Diego pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in San Diego?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in San Diego, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in San Diego?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.

Paid clinical trials near San Diego

Other metros within reach

Chula Vista, CA1,260 Escondido, CA1,291 Oceanside, CA707 Hemet, CA337 Mission Viejo, CA1,380 Irvine, CA1,516 Moreno Valley, CA435 Corona, CA1,565

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in San Diego Severe Chronic Pruritus in San Diego Bladder Issues Due To Spinal Cord Injury in San Diego All conditions

More of CA

Long Beach3,348 Torrance3,239 Fullerton3,230 Anaheim3,164 Garden Grove3,162 Pomona3,123 Glendale2,948 Los Angeles2,936 Huntington Beach2,847 Santa Clarita2,389 Hayward2,266 Oakland2,257

New paid studies open every week

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