Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/MA/Worcester
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Worcester, MA

Studies commonly pay $75 to $4,500 per completed study

269 clinical trials are currently recruiting participants within 30 miles of Worcester. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

269studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Worcester right now

Top 25 of 269 recruiting studies, sorted by proximity — each links to its official registry page

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
UMass Memorial Medical Center - University Campus — Worcester, Massachusetts (0.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

Myasthenia Gravis Foundation of America Global MG Patient Registry

Myasthaenia Gravis, Myasthenia N/A Observational 3,800 participants sought
Myasthenia Gravis Foundation of America — Westborough, Massachusetts (9.8 mi) · Sponsor: Myasthenia Gravis Foundation of America
See eligibility & contact on ClinicalTrials.gov (NCT06617741)

Phase 2 Study to Evaluate EI-001 in Non-segmental Vitiligo Patients

Non-segmental Vitiligo Phase 2 Interventional 45 participants sought
U Mass Chan Medical School — Worcester, Massachusetts (0.6 mi) · Sponsor: Elixiron Immunotherapeutics (Hong Kong) Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT07223229)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
UMass Memorial Medical Center - University Campus — Worcester, Massachusetts (0.6 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Worcester, Massachusetts (0.6 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
University of Massachusetts Medical School — Worcester, Massachusetts (0.6 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma

PTSD, Alcohol; Use, Problem N/A Interventional 144 participants sought
University of Massachusetts Medical School — Worcester, Massachusetts (0.6 mi) · Sponsor: University of Massachusetts, Worcester
See eligibility & contact on ClinicalTrials.gov (NCT06278922)

Promoting Improved Functioning Among People Experiencing Stressful Situations

Acute Stress Reaction N/A Interventional 450 participants sought
University of Massachusetts Chan Medical School — Worcester, Massachusetts (0.6 mi) · Sponsor: University of North Carolina, Chapel Hill
See eligibility & contact on ClinicalTrials.gov (NCT06482567)

An Evaluation of the Effect of the Erchonia FX-405 Laser as an Adjunctive Treatment of Periodontitis

Periodontal Diseases, Periodontitis N/A Interventional 70 participants sought
Acton Dental Associates — Acton, Massachusetts (24.2 mi) · Sponsor: Erchonia Corporation
See eligibility & contact on ClinicalTrials.gov (NCT06656325)

Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients

Irritability Associated With Autism Spectrum Disorder Phase 3 Interventional 160 participants sought
UMass Memorial Healthcare — Worcester, Massachusetts (0.6 mi) · Sponsor: Intra-Cellular Therapies, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06690398)

Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

Colorectal Neoplasms Phase 3 Interventional 300 participants sought
University of Massachusetts — Worcester, Massachusetts (0.6 mi) · Sponsor: Surgimab
See eligibility & contact on ClinicalTrials.gov (NCT03659448)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
UMass Memorial Medical Center - University Campus — Worcester, Massachusetts (0.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

Migraine Phase 3 Interventional 200 participants sought
New England Regional Headache Center — Worcester, Massachusetts (0.6 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT06616194)

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 Phase 3 Interventional 1,875 participants sought
UMass Memorial Medical Center - University Campus — Worcester, Massachusetts (0.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05675410)

Retropubic Hydrodissection and Trocar-induced Bladder Perforation During Retropubic Midurethral Slings

Bladder Perforation, Retropubic Midurethral Sling N/A Interventional 300 participants sought
University of Massachusetts Memorial Medical Center — Worcester, Massachusetts (0.6 mi) · Sponsor: University of Massachusetts, Worcester
See eligibility & contact on ClinicalTrials.gov (NCT07208682)

Testimonials and Navigation in Rheumatology

Rheumatologic Disease, Autoimmune Diseases N/A Interventional 1,170 participants sought
University of Massachusetts Chan Medical School — Worcester, Massachusetts (0.6 mi) · Sponsor: University of Alabama at Birmingham
See eligibility & contact on ClinicalTrials.gov (NCT06469788)

Cytomegalovirus (CMV) Transmission and Immune Tracking (TransmIT) Study

Cytomegalovirus Infections N/A Observational 100 participants sought
UMass Chan Medical School — Worcester, Massachusetts (0.6 mi) · Sponsor: University of Massachusetts, Worcester
See eligibility & contact on ClinicalTrials.gov (NCT06522880)

Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

Atopic Dermatitis N/A Observational 1,000 participants sought
Galderma Investigationa Site 7104 — Milford, Massachusetts (17.4 mi) · Sponsor: Galderma R&D
See eligibility & contact on ClinicalTrials.gov (NCT06988605)

A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis

Systemic Sclerosis Phase 3 Interventional 92 participants sought
Local Institution - 0084 — Worcester, Massachusetts (0.6 mi) · Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
See eligibility & contact on ClinicalTrials.gov (NCT07335562)

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

Breast Cancer, Triple Negative Breast Cancer Phase 2 Interventional 110 participants sought
DFCI @ Milford Regional Hospital — Milford, Massachusetts (17.4 mi) · Sponsor: Dana-Farber Cancer Institute
See eligibility & contact on ClinicalTrials.gov (NCT04468061)
Actively enrolling

Studies you may be able to join near Worcester

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Worcester

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Reliant Medical Group Research Department

640 Lincoln St, Worcester, MA 01605
(508) 595-2195

PracticePoint: Accelerating Medtech Innovation & Empowering Medskill Training

★ 5.0
Gateway Park II, 50 Prescott St, Worcester, MA 01605
(508) 831-4653

Meyers Health Care Institute

385 Grove St, Worcester, MA 01605
(508) 791-7392

Center For Outcomes Research

55 N Lake Ave, Worcester, MA 01655
(508) 856-1336

UMass Cancer Walk

55 N Lake Ave, Worcester, MA 01655
(508) 856-2589

Community Healthlink, Inc.

★ 2.5
72 Jaques Ave, Worcester, MA 01610
(508) 860-1000

Eunice Kennedy Shriver Center

55 N Lake Ave, Worcester, MA 01655
(774) 455-6562

Behavioral Healthcare Services

★ 3.3 (185 reviews)
435 Shrewsbury St, Worcester, MA 01604
(508) 753-5554
"I had a very disappointing experience with Sherrie Urena. I arrived on time for my scheduled appointment, but after waiting over 30 minutes without b…"
— Christina Garoulis, 1★

Clinical Trials of New England

1234 Hyde Park Ave #205, Hyde Park, MA 02136

Clinical trials in Worcester: what's recruiting

The Worcester area currently has 269 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Worcester, the most active research areas are:

  • Cancer & Oncology8 studies
  • Brain & Mental Health1 studies
  • Immune & Skin1 studies
  • Lungs & Breathing1 studies

Every listing shows the study phase, the recruiting site and its distance from Worcester, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Worcester

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Worcester participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in Worcester safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Worcester, MA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Worcester?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Worcester?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Worcester.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Worcester typically complete one or two studies per year.

Paid clinical trials near Worcester

Other metros within reach

Nashua, NH254 Providence, RI550 Boston, MA2,944 Springfield, MA325 Norwich, CT122 Manchester, NH89 Hartford, CT447 New Bedford, MA511

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Worcester Bladder Issues Due To Spinal Cord Injury in Worcester All conditions

More of MA

Boston2,944 New Bedford511 Springfield325

New paid studies open every week

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