Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/MA/Boston
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Boston, MA

Studies commonly pay $75 to $4,500 per completed study

2,966 clinical trials are currently recruiting participants within 30 miles of Boston. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

2,966studies recruiting
9+research centers nearby
7condition categories
Live from the NIH registry

Studies recruiting near Boston right now

Top 25 of 2,966 recruiting studies, sorted by proximity — each links to its official registry page

RESOLVE: Abemaciclib + Letrozole +/- Metformin or Gedatolisib in Endometrial Cancer

Endometrial Cancer Phase 2 Interventional 110 participants sought
Massachusetts General Hospital Cancer Center — Boston, Massachusetts (3.0 mi) · Sponsor: Dana-Farber Cancer Institute
See eligibility & contact on ClinicalTrials.gov (NCT03675893)

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

High Grade Glioma, Diffuse Intrinsic Pontine Glioma Phase 2 Interventional 120 participants sought
Dana-Farber Cancer Institute — Boston, Massachusetts (3.0 mi) · Sponsor: Nationwide Children's Hospital
See eligibility & contact on ClinicalTrials.gov (NCT05096481)

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC) Phase 1 Interventional 604 participants sought
Massachusetts General Hospital — Boston, Massachusetts (3.0 mi) · Sponsor: Revolution Medicines, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06040541)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Dana-Farber Cancer Institute — Boston, Massachusetts (3.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis

Congenital Heart Disease, Single-ventricle N/A Observational 10 participants sought
Boston Children's Hospital — Boston, Massachusetts (3.0 mi) · Sponsor: Boston Children's Hospital
See eligibility & contact on ClinicalTrials.gov (NCT06434207)

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

HIV-1-infection, Frailty Phase 2 Interventional 100 participants sought
Massachusetts General Hospital — Boston, Massachusetts (3.0 mi) · Sponsor: Massachusetts General Hospital
See eligibility & contact on ClinicalTrials.gov (NCT06554717)

Effects of IL-1 Beta Inhibition on Vascular Inflammation in TET2 Clonal Hematopoiesis

Vascular Inflammation, ASCVD Phase 2 Interventional 120 participants sought
Massachusetts General Hospital — Boston, Massachusetts (3.0 mi) · Sponsor: Massachusetts General Hospital
See eligibility & contact on ClinicalTrials.gov (NCT06691217)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
Beth Israel Deaconess Medical Center ( Site 0161) — Boston, Massachusetts (3.0 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

SARC046: A Phase II Trial of Nab-Sirolimus in Patients With Progressing or Symptomatic Epithelioid Hemangioendothelioma

Epithelioid Hemangioendothelioma (EHE) Phase 2 Interventional 41 participants sought
Brigham and Women's Hospital — Boston, Massachusetts (3.0 mi) · Sponsor: Sarcoma Alliance for Research through Collaboration
See eligibility & contact on ClinicalTrials.gov (NCT07104331)

Assess Fibrin in Brains With AD/ADRD

Alzheimer Disease, Dementia of Alzheimer Type Phase 1, Phase 2 Interventional 30 participants sought
Massachusetts General Hospital — Boston, Massachusetts (3.0 mi) · Sponsor: Massachusetts General Hospital
See eligibility & contact on ClinicalTrials.gov (NCT05336695)

BE WELL With Migraine: Brain Education and WELLness With Migraine

Migraine N/A Interventional 286 participants sought
Cambridge Health Alliance - Center for Mindfulness and Compassion — Cambridge, Massachusetts (4.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT05987592)

Integrated Treatment for Enhancing Growth in Recovery During Adolescence

Alcohol Use Disorder, Cannabis Use Disorder N/A Interventional 294 participants sought
MGH Department of Psychiatry — Boston, Massachusetts (3.0 mi) · Sponsor: Massachusetts General Hospital
See eligibility & contact on ClinicalTrials.gov (NCT06395467)

Training Inner Speech in Children With Developmental Language Disorder

Developmental Language Disorder N/A Interventional 75 participants sought
MGH Institute of Health Professions — Boston, Massachusetts (3.0 mi) · Sponsor: MGH Institute of Health Professions
See eligibility & contact on ClinicalTrials.gov (NCT06880731)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Tufts Medical Center — Boston, Massachusetts (3.0 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design

Fibromyalgia Phase 3 Interventional 620 participants sought
Clinical Research Site — Boston, Massachusetts (3.0 mi) · Sponsor: Axsome Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07398417)

Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression

Treatment Resistant Depression (TRD) N/A Interventional 20 participants sought
Massachusetts General Hospital's Depression and Clinical Research program — Boston, Massachusetts (3.0 mi) · Sponsor: Massachusetts General Hospital
See eligibility & contact on ClinicalTrials.gov (NCT07563868)

International Weight Control Registry

Weight Loss, Overweight N/A Observational 100,000 participants sought
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University — Boston, Massachusetts (3.0 mi) · Sponsor: Tufts University
See eligibility & contact on ClinicalTrials.gov (NCT04907396)

ViTAA Registry Pre- and Post-Operative Monitoring for Endovascular Aortic Aneurysm Repair and Serial Monitoring for AAA

Abdominal Aortic Aneurysms N/A Observational 200 participants sought
MGH - Massachusetts General Hospital Fireman Vascular Center — Boston, Massachusetts (3.0 mi) · Sponsor: ViTAA Medical Solutions
See eligibility & contact on ClinicalTrials.gov (NCT05004051)

Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial

Graft Vs Host Disease, Acute-graft-versus-host Disease N/A Interventional 36 participants sought
Brigham and Women's Hospital — Boston, Massachusetts (3.0 mi) · Sponsor: Dana-Farber Cancer Institute
See eligibility & contact on ClinicalTrials.gov (NCT05236062)

APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women

Overactive Bladder (OAB), Urinary Urgency N/A Interventional 596 participants sought
Curavit — Boston, Massachusetts (3.0 mi) · Sponsor: Medstar Health Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT06797245)

Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults

Acute Respiratory Failure N/A Observational 2,092 participants sought
Lahey Hospital & Medical Center — Burlington, Massachusetts (14.0 mi) · Sponsor: Brian Driver
See eligibility & contact on ClinicalTrials.gov (NCT06934876)
Actively enrolling

Studies you may be able to join near Boston

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Boston

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

DM Clinical Research-Brookline

★ 4.8
209 Harvard St #502, Brookline, MA 02446
(857) 410-9993
"They have been robo calling me with an AI bot of some kind, plus texts and emails. It's unbelievably irritating."
— Matthew O'Rourke, 1★

BMC Clinical Research Unit

850 Harrison Ave 6th floor, Boston, MA 02118
(617) 638-8855

MIT Clinical Research Center

45, 201 Carleton St E25, Cambridge, MA 02142
(617) 253-6331

Boston Clinical Trials

6 Liberty Sq PMB # 317, Boston, MA 02109

Boston Clinical Trials

★ 4.4
26 Cummins Hwy, Boston, MA 02131
(617) 477-4868
"Very well organized and telephone health checks were very helpful in getting a good sample collection. Would do this again if offered."
— Mary Wolfe, 5★

Tufts Medical Center Clinical + Translational Research Center (CTRC)

North Building, 800 Washington St 6th Floor, Boston, MA 02111
(617) 636-5973

Center for Community-Based Research

450 Brookline Ave LW703, Boston, MA 02215
(617) 632-4673

CIB

50 Staniford St Unit 401, Boston, MA 02114
(855) 275-6387

Center for Regenerative Medicine, Boston University Medical Campus

★ 5.0
670 Albany St Fl 2, Boston, MA 02118
(203) 391-4681

Clinical trials in Boston: what's recruiting

The Boston area currently has 2,966 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Boston, the most active research areas are:

  • Cancer & Oncology8 studies
  • Diabetes & Metabolism3 studies
  • Brain & Mental Health3 studies
  • Heart & Vascular2 studies
  • Lungs & Breathing1 studies

Every listing shows the study phase, the recruiting site and its distance from Boston, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Boston

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Boston participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Boston pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Boston?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Boston?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Boston.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Boston typically complete one or two studies per year.

Paid clinical trials near Boston

Other metros within reach

Nashua, NH263 Providence, RI554 New Bedford, MA517 Worcester, MA270 Manchester, NH83 Norwich, CT115 Springfield, MA315 Portland, ME165

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Boston Chronic Kidney Disease (HealthMatch) in Boston Bladder Issues Due To Spinal Cord Injury in Boston All conditions

More of MA

New Bedford517 Springfield315 Worcester270

New paid studies open every week

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