Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/MI/South Lyon
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in South Lyon, MI

Studies commonly pay $75 to $4,500 per completed study

1,319 clinical trials are currently recruiting participants within 30 miles of South Lyon. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,319studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near South Lyon right now

Top 25 of 1,319 recruiting studies, sorted by proximity — each links to its official registry page

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

High Grade Glioma, Diffuse Intrinsic Pontine Glioma Phase 2 Interventional 120 participants sought
C.S. Mott Children's Hospital — Ann Arbor, Michigan (13.5 mi) · Sponsor: Nationwide Children's Hospital
See eligibility & contact on ClinicalTrials.gov (NCT05096481)

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A

Von Willebrand Disease, Type 3, Concomitant VWD and Hemophilia Phase 1 Interventional 40 participants sought
University of Michigan Medical School — Ann Arbor, Michigan (13.5 mi) · Sponsor: Bleeding and Clotting Disorders Institute Peoria, Illinois
See eligibility & contact on ClinicalTrials.gov (NCT05500807)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
C S Mott Children's Hospital — Ann Arbor, Michigan (13.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

Thrombocythemia, Essential, Primary Myelofibrosis Phase 3 Interventional 400 participants sought
University of Michigan ( Site 6000) — Ann Arbor, Michigan (13.5 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06351631)

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Phase 2 Interventional 120 participants sought
Detroit Clinical Research Center — Farmington Hills, Michigan (14.1 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06465329)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
University of Michigan — Ann Arbor, Michigan (13.5 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

Acute Myeloid Leukemia (AML) Phase 3 Interventional 1,300 participants sought
University of Michigan — Ann Arbor, Michigan (13.5 mi) · Sponsor: Kura Oncology, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07007312)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Trinity Health IHA Medical Group Hematology Oncology - Brighton — Brighton, Michigan (8.0 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD

Age-Related Macular Degeneration, Geographic Atrophy N/A Interventional 125 participants sought
Oakland Ophthalmic Surgery — Birmingham, Michigan (23.2 mi) · Sponsor: VisionCare, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05438732)

Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy

Pain, Postoperative, Intrathoracic Procedure N/A Interventional 80 participants sought
University of Michigan — Ann Arbor, Michigan (13.5 mi) · Sponsor: University of Michigan
See eligibility & contact on ClinicalTrials.gov (NCT06384664)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Ann Arbor, Michigan (13.5 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease

Hypertension, Pulmonary, Lung Diseases, Interstitial Phase 2 Interventional 25 participants sought
Allen Park — Allen Park, Michigan (26.6 mi) · Sponsor: Tectonic Operating Company, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07473700)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Associated Retinal Consultants PC — Royal Oak, Michigan (26.0 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Ann Arbor, Michigan (13.5 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06129864)

Virtual Reality (VR) -Directed Brain Gut Behavioral Treatment (BGBT) for Inflammatory Bowel Disease (IBD) Inpatients

Inflammatory Bowel Diseases N/A Interventional 40 participants sought
University of Michigan — Ann Arbor, Michigan (13.5 mi) · Sponsor: University of Michigan
See eligibility & contact on ClinicalTrials.gov (NCT06188793)

Study Evaluating the Safety and Efficacy of Neffy or Intramuscular Adrenalin in Patients With Allergic Reactions After Oral Food Challenge or Allergen Immunotherapy

Allergic Reactions Phase 4 Interventional 600 participants sought
University Of Michigan — Ann Arbor, Michigan (13.5 mi) · Sponsor: ARS Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06834165)

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Metastatic Castration Sensitive Prostate Cancer (mCSPC), Hormone Sensitive Prostate Cancer Phase 3 Interventional 1,000 participants sought
Michigan Institute of Urology, PC — Troy, Michigan (27.5 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07028853)

Treatment of the Biceps With Concomitant Supraspinatus Tears

Supraspinatus Tear N/A Interventional 180 participants sought
Sports Medicine and Shoulder Surgery, University of Michigan — Ann Arbor, Michigan (13.5 mi) · Sponsor: La Tour Hospital
See eligibility & contact on ClinicalTrials.gov (NCT05660031)

Evaluating the Role of the Guidewire in Peripheral Intravenous Access: A Randomized Controlled Trial of Ultrasound-Guided Catheter Survival

Peripheral Intravenous Vein Catheter Phlebitis, Intravenous Infection N/A Interventional 360 participants sought
Beaumont Hospital - Royal Oak — Royal Oak, Michigan (26.0 mi) · Sponsor: Corewell Health East
See eligibility & contact on ClinicalTrials.gov (NCT06107361)

Move and Snooze: Adding Insomnia Treatment to an Exercise Program to Improve Pain Outcomes in Older Adults With Knee Osteoarthritis

Knee Osteoarthritis, Insomnia N/A Interventional 288 participants sought
University of Michigan — Ann Arbor, Michigan (13.5 mi) · Sponsor: University of Michigan
See eligibility & contact on ClinicalTrials.gov (NCT06580561)

BSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS

AML, Adult Recurrent, ALL, Recurrent, Adult Phase 1, Phase 2 Interventional 38 participants sought
University of Michigan — Ann Arbor, Michigan (13.5 mi) · Sponsor: BlueSphere Bio, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06704152)
Actively enrolling

Studies you may be able to join near South Lyon

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in South Lyon

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Detroit Clinical Research Center

★ 5.0
30160 Orchard Lake Rd #110, Farmington Hills, MI 48334
(248) 737-5939

Bolt Clinical Research

609 W Main St, Brighton, MI 48116
(989) 996-0860

Michigan Center of Medical Research

★ 3.0
30160 Orchard Lake Rd #160, Farmington Hills, MI 48334
(248) 747-4383
"Dr Green has lefted the office. If you have medication. You better check up on them. They didn't even tell me till I called them. With a problem. Ex…"
— feather smith, 1★

Michigan Institute for Clinical & Health Research

★ 5.0
1600 Huron Pkwy, Ann Arbor, MI 48105
(734) 998-7474

Quest Research Institute

★ 4.9
28555 Orchard Lake Rd Computer Lab, Farmington Hills, MI 48334
(248) 957-8940
"Grateful for the opportunity to participate in this clinical trial."
— Magra, 5★

Revive Research Institute

★ 3.7
28266 Franklin Rd, Southfield, MI 48034
(248) 721-9539
"Khalida and anitha are the most professional caring healthcare workers i have ever encountered thank you so much for you're patients and you're help …"
— Sara, 5★

DM Clinical Research-Detroit

★ 4.7
20180 W 12 Mile Rd Ste 400, Southfield, MI 48076
(313) 513-1616
"Very friendly very welcoming very nice overall"
— Aidan Nason, 5★

Revival Research Institute

★ 3.7
28270 Franklin Rd, Southfield, MI 48034
(248) 721-9539

Headlands Research Detroit

★ 4.7
29355 Northwestern Hwy #200, Southfield, MI 48034
(248) 243-1870
"Warm, friendly staff - great experience and awesome to work with!"
— Gina Angellotti, 5★

Clinical trials in South Lyon: what's recruiting

The South Lyon area currently has 1,319 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to South Lyon, the most active research areas are:

  • Cancer & Oncology9 studies
  • Immune & Skin3 studies
  • Heart & Vascular2 studies
  • Lungs & Breathing1 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from South Lyon, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in South Lyon

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

South Lyon participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in South Lyon?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in South Lyon safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in South Lyon, MI?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in South Lyon?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in South Lyon?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of South Lyon.

Paid clinical trials near South Lyon

Other metros within reach

Ann Arbor, MI1,172 Detroit, MI1,197 Flint, MI175 Toledo, OH211 Lansing, MI178 Lorain, OH1,309 Kalamazoo, MI106 Fort Wayne, IN115

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in South Lyon Chronic Kidney Disease (HealthMatch) in South Lyon Bladder Issues Due To Spinal Cord Injury in South Lyon All conditions

More of MI

Detroit1,197 Ann Arbor1,172 Grand Rapids458 Lansing178 Flint175 Kalamazoo106 Muskegon60

New paid studies open every week

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