Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/MI/Detroit
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Detroit, MI

Studies commonly pay $75 to $4,500 per completed study

1,197 clinical trials are currently recruiting participants within 30 miles of Detroit. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,197studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Detroit right now

Top 25 of 1,197 recruiting studies, sorted by proximity — each links to its official registry page

Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD

Age-Related Macular Degeneration, Geographic Atrophy N/A Interventional 125 participants sought
Oakland Ophthalmic Surgery — Birmingham, Michigan (12.6 mi) · Sponsor: VisionCare, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05438732)

Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma

Large Cell Lymphoma, Diffuse, Relapsed Cancer Phase 2 Interventional 35 participants sought
Karmanos Cancer Center (Wayne State University) — Detroit, Michigan (4.6 mi) · Sponsor: Dipenkumar Modi
See eligibility & contact on ClinicalTrials.gov (NCT05852717)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Children's Hospital of Michigan — Detroit, Michigan (4.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Phase 2 Interventional 120 participants sought
Karmanos Cancer Institute — Detroit, Michigan (4.6 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06465329)

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis Phase 2 Interventional 168 participants sought
St. Clair Nephrology Research — Shelby, Michigan (20.2 mi) · Sponsor: R1 Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06712654)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Profound Research LLC — Royal Oak, Michigan (7.6 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease

Hypertension, Pulmonary, Lung Diseases, Interstitial Phase 2 Interventional 25 participants sought
Allen Park — Allen Park, Michigan (10.3 mi) · Sponsor: Tectonic Operating Company, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07473700)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Wayne State University/Karmanos Cancer Institute — Detroit, Michigan (4.6 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Detroit, Michigan (4.6 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

Acute Myeloid Leukemia (AML) Phase 3 Interventional 1,300 participants sought
Wayne State University School of Medicine — Detroit, Michigan (4.6 mi) · Sponsor: Kura Oncology, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07007312)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
Karmanos Cancer Institute — Detroit, Michigan (4.6 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma, Relapsed/Refractory Multiple Myeloma Phase 2 Interventional 100 participants sought
Karmanos Cancer Institute — Detroit, Michigan (4.6 mi) · Sponsor: C4 Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07284758)

ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile Infection

Clostridium Difficile Infection Recurrence Phase 2 Interventional 20 participants sought
Henry Ford Hospital — Detroit, Michigan (4.6 mi) · Sponsor: Acurx Pharmaceuticals Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07513285)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Associated Retinal Consultants PC — Royal Oak, Michigan (7.6 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma Phase 2, Phase 3 Interventional 455 participants sought
Karmanos Cancer Center — Detroit, Michigan (4.6 mi) · Sponsor: Oncotelic Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06079346)

A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

Diffuse Cutaneous Systemic Sclerosis Phase 2 Interventional 200 participants sought
Wayne State University — Detroit, Michigan (4.6 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06470048)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Detroit, Michigan (4.6 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Non-Small Cell Lung Cancer Phase 3 Interventional 675 participants sought
Research Site — Dearborn, Michigan (5.7 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06357533)

Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks

Acute Hereditary Angio Edema Phase 3 Interventional 124 participants sought
Octapharma Research Site — Farmington Hills, Michigan (15.7 mi) · Sponsor: Octapharma
See eligibility & contact on ClinicalTrials.gov (NCT06361537)

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Percutaneous Coronary Intervention, Peripheral Endovascular Intervention Phase 4 Interventional 6,000 participants sought
Healthy Heart Cardiology at Rochester Hills (Advanced Cardiology Associates — Rochester Hills, Michigan (19.2 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT06909565)
Actively enrolling

Studies you may be able to join near Detroit

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Detroit

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Clinical Trials Office, Karmanos Cancer Institute

★ 3.0
87 E Canfield St Storefront, Detroit, MI 48201
(313) 576-9790
"Never go to this place! They are very rude so is the dr and they are only about there money! Very very bad place"
— Danielle Goble, 1★

WSU Integrative Biosciences Center

★ 4.9
6135 Woodward Ave, Detroit, MI 48202
(313) 577-1771
"Great Staff, hopefully this tinnitus study and its results helps the millions of people that deal with this disease. 🙏"
— Thomas Ruszkiewicz Jr, 5★

Vitalis Clinical Research Center

★ 5.0
7445 Allen Rd #260, Allen Park, MI 48101
(313) 887-4536
"The ladies are very nice and professional. Kiya is the greatest. She explains everything to the fullest"
— Ace Boogie, 5★

Detroit Clinical Research Center

★ 5.0
30160 Orchard Lake Rd #110, Farmington Hills, MI 48334
(248) 737-5939

Mott Center For Human Growth

C. S. Mott Center for Human Growth and Development, 275 E Hancock St, Detroit, MI 48201
(313) 577-1485

Flourish Research - Detroit

★ 3.3
20755 Greenfield Rd #107, Southfield, MI 48075
(248) 864-5242
"My experience with them is one of deceit and changing of information as it fits them. They have the recruiters take your all history and medication h…"
— Marie Berry, 1★

DM Clinical Research-Detroit

★ 4.7
20180 W 12 Mile Rd Ste 400, Southfield, MI 48076
(313) 513-1616
"Very friendly very welcoming very nice overall"
— Aidan Nason, 5★

STARC Lab

3901 Chrysler Dr, Detroit, MI 48201

Henry Ford Cancer - Detroit

★ 4.2 (89 reviews)
2800 W Grand Blvd, Detroit, MI 48202
(888) 246-6424
"Hello,I really do not complain about customer service but in one of your department,they picked up the phone rude,and they had the nerve to hang up …"
— Melinda Alford, 1★

Clinical trials in Detroit: what's recruiting

The Detroit area currently has 1,197 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Detroit, the most active research areas are:

  • Cancer & Oncology13 studies
  • Heart & Vascular3 studies
  • Brain & Mental Health2 studies
  • Liver & Kidney1 studies
  • Lungs & Breathing1 studies

Every listing shows the study phase, the recruiting site and its distance from Detroit, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Detroit

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Detroit participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Detroit?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Detroit safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Detroit?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Detroit.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Detroit typically complete one or two studies per year.

Paid clinical trials near Detroit

Other metros within reach

South Lyon, MI1,319 Ann Arbor, MI1,172 Toledo, OH211 Flint, MI175 Lorain, OH1,309 Lansing, MI178 Cleveland, OH1,413 Akron, OH394

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Detroit Chronic Kidney Disease (HealthMatch) in Detroit Bladder Issues Due To Spinal Cord Injury in Detroit All conditions

More of MI

South Lyon1,319 Ann Arbor1,172 Grand Rapids458 Lansing178 Flint175 Kalamazoo106 Muskegon60

New paid studies open every week

Get an email when a new clinical trial starts recruiting within 30 miles of your ZIP code. No spam — only real studies from the NIH registry.

By subscribing you agree to receive study alert emails. Unsubscribe anytime in one click.

Get free trial alerts