Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/MI/Detroit
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Detroit, MI

Studies commonly pay $75 to $4,500 per completed study

1,190 clinical trials are currently recruiting participants within 30 miles of Detroit. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,190studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Detroit right now

Top 25 of 1,190 recruiting studies, sorted by proximity — each links to its official registry page

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Children's Hospital of Michigan — Detroit, Michigan (4.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Phase 2 Interventional 120 participants sought
Karmanos Cancer Institute — Detroit, Michigan (4.6 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06465329)

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis Phase 2 Interventional 168 participants sought
St. Clair Nephrology Research — Shelby, Michigan (20.2 mi) · Sponsor: R1 Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06712654)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Profound Research LLC — Royal Oak, Michigan (7.6 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Wayne State University/Karmanos Cancer Institute — Detroit, Michigan (4.6 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Detroit, Michigan (4.6 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
Karmanos Cancer Institute — Detroit, Michigan (4.6 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Associated Retinal Consultants PC — Royal Oak, Michigan (7.6 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma Phase 2, Phase 3 Interventional 455 participants sought
Karmanos Cancer Center — Detroit, Michigan (4.6 mi) · Sponsor: Oncotelic Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06079346)

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Percutaneous Coronary Intervention, Peripheral Endovascular Intervention Phase 4 Interventional 6,000 participants sought
Healthy Heart Cardiology at Rochester Hills (Advanced Cardiology Associates — Rochester Hills, Michigan (19.2 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT06909565)

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Metastatic Castration Sensitive Prostate Cancer (mCSPC), Hormone Sensitive Prostate Cancer Phase 3 Interventional 1,000 participants sought
Michigan Institute of Urology, PC — Troy, Michigan (15.5 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07028853)

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma Phase 3 Interventional 1,524 participants sought
Henry Ford Hospital — Detroit, Michigan (4.6 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT07200830)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
Ascension Saint John Hospital — Detroit, Michigan (4.6 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05561387)

Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

Systemic Lupus Erythematosus Phase 3 Interventional 550 participants sought
Henry Ford Health — Detroit, Michigan (4.6 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06133972)

Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

COPD, Chronic Obstructive Pulmonary Disease N/A Interventional 200 participants sought
Henry Ford Hospital - Lung and Pulmonary Care — Detroit, Michigan (4.6 mi) · Sponsor: Nuvaira, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07051707)

Evaluating the Role of the Guidewire in Peripheral Intravenous Access: A Randomized Controlled Trial of Ultrasound-Guided Catheter Survival

Peripheral Intravenous Vein Catheter Phlebitis, Intravenous Infection N/A Interventional 360 participants sought
Beaumont Hospital - Royal Oak — Royal Oak, Michigan (7.6 mi) · Sponsor: Corewell Health East
See eligibility & contact on ClinicalTrials.gov (NCT06107361)

Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

Viral Pneumonia Phase 2 Interventional 550 participants sought
Sinai-Grace Hospital — Detroit, Michigan (4.6 mi) · Sponsor: Synairgen Research Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT06999603)

Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa

Hidradenitis Suppurativa Phase 1 Interventional 24 participants sought
Revival Research Institute, Llc Troy — Troy, Michigan (15.5 mi) · Sponsor: Incyte Corporation
See eligibility & contact on ClinicalTrials.gov (NCT07049575)

A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System

Atrial Fibrillation N/A Interventional 276 participants sought
Trinity Health — Ypsilanti, Michigan (27.9 mi) · Sponsor: Biosense Webster, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07227532)

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

Aortic Valve Insufficiency, Aortic Valve Stenosis N/A Interventional 200 participants sought
Henry Ford Hospital Detroit — Detroit, Michigan (4.6 mi) · Sponsor: Edwards Lifesciences
See eligibility & contact on ClinicalTrials.gov (NCT05172973)
Actively enrolling

Studies you may be able to join near Detroit

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Detroit

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Clinical Trials Office, Karmanos Cancer Institute

★ 3.0
87 E Canfield St Storefront, Detroit, MI 48201
(313) 576-9790
"Never go to this place! They are very rude so is the dr and they are only about there money! Very very bad place"
— Danielle Goble, 1★

WSU Integrative Biosciences Center

★ 4.9
6135 Woodward Ave, Detroit, MI 48202
(313) 577-1771
"Great Staff, hopefully this tinnitus study and its results helps the millions of people that deal with this disease. 🙏"
— Thomas Ruszkiewicz Jr, 5★

Vitalis Clinical Research Center

★ 5.0
7445 Allen Rd #260, Allen Park, MI 48101
(313) 887-4536
"The ladies are very nice and professional. Kiya is the greatest. She explains everything to the fullest"
— Ace Boogie, 5★

Detroit Clinical Research Center

★ 5.0
30160 Orchard Lake Rd #110, Farmington Hills, MI 48334
(248) 737-5939

Mott Center For Human Growth

C. S. Mott Center for Human Growth and Development, 275 E Hancock St, Detroit, MI 48201
(313) 577-1485

Flourish Research - Detroit

★ 3.3
20755 Greenfield Rd #107, Southfield, MI 48075
(248) 864-5242
"My experience with them is one of deceit and changing of information as it fits them. They have the recruiters take your all history and medication h…"
— Marie Berry, 1★

DM Clinical Research-Detroit

★ 4.7
20180 W 12 Mile Rd Ste 400, Southfield, MI 48076
(313) 513-1616
"Very friendly very welcoming very nice overall"
— Aidan Nason, 5★

STARC Lab

3901 Chrysler Dr, Detroit, MI 48201

Henry Ford Cancer - Detroit

★ 4.2 (89 reviews)
2800 W Grand Blvd, Detroit, MI 48202
(888) 246-6424
"Hello,I really do not complain about customer service but in one of your department,they picked up the phone rude,and they had the nerve to hang up …"
— Melinda Alford, 1★

Clinical trials in Detroit: what's recruiting

The Detroit area currently has 1,190 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Detroit, the most active research areas are:

  • Cancer & Oncology11 studies
  • Heart & Vascular2 studies
  • Immune & Skin2 studies
  • Liver & Kidney1 studies
  • Brain & Mental Health1 studies

Every listing shows the study phase, the recruiting site and its distance from Detroit, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Detroit

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Detroit participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Detroit?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Detroit safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Detroit?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Detroit.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Detroit typically complete one or two studies per year.

Paid clinical trials near Detroit

Other metros within reach

South Lyon, MI1,329 Ann Arbor, MI1,186 Toledo, OH208 Flint, MI182 Lorain, OH1,304 Lansing, MI183 Cleveland, OH1,409 Akron, OH394

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Detroit Chronic Kidney Disease (HealthMatch) in Detroit Bladder Issues Due To Spinal Cord Injury in Detroit All conditions

More of MI

South Lyon1,329 Ann Arbor1,186 Grand Rapids456 Lansing183 Flint182 Kalamazoo107 Muskegon61

New paid studies open every week

Get an email when a new clinical trial starts recruiting within 30 miles of your ZIP code. No spam — only real studies from the NIH registry.

By subscribing you agree to receive study alert emails. Unsubscribe anytime in one click.

Get free trial alerts