Live from the NIH registry
Studies recruiting near Lorain right now
Top 25 of 1,304 recruiting studies, sorted by proximity — each links to its official registry page
KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)
Carcinoma, Non-Small-Cell Lung
Phase 1, Phase 2
Interventional 450 participants sought
Cleveland Clinic Main ( Site 0006) — Cleveland, Ohio (25.6 mi)
· Sponsor: Merck Sharp & Dohme LLC
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
B Acute Lymphoblastic Leukemia
Phase 2
Interventional 222 participants sought
Rainbow Babies and Childrens Hospital — Cleveland, Ohio (25.6 mi)
· Sponsor: National Cancer Institute (NCI)
Treatment of Moderate to Severe Refractory Crohn's Disease
Crohns Disease
Phase 1, Phase 2
Interventional 39 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Tr1X, Inc.
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
N/A
Interventional 400 participants sought
University Hospitals Cleveland Medical Center — Cleveland, Ohio (25.6 mi)
· Sponsor: Medtronic MiniMed, Inc.
A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)
Neovascular Age-related Macular Degeneration
Phase 4
Interventional 188 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Genentech, Inc.
A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF SHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS
Advanced Solid Tumors
Phase 1, Phase 2
Interventional 83 participants sought
University Hospitals Cleveland Medical Center — Cleveland, Ohio (25.6 mi)
· Sponsor: Jiangsu HengRui Medicine Co., Ltd.
Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
N/A
Interventional 14 participants sought
Cleveland State University — Cleveland, Ohio (25.6 mi)
· Sponsor: Cionic, Inc.
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation
Atrial Fibrillation, Obesity
Phase 2
Interventional 100 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: The Cleveland Clinic
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Bladder Carcinoma, Ureter Carcinoma
N/A
Observational 2,020 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Guardant Health, Inc.
Milk Thistle Clinical Trial in Pediatric NAFLD
Non-Alcoholic Fatty Liver Disease (NAFLD)
Phase 2
Interventional 20 participants sought
University Hospitals Cleveland Medical Center — Cleveland, Ohio (25.6 mi)
· Sponsor: University Hospitals Cleveland Medical Center
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Metastatic Castration Sensitive Prostate Cancer (mCSPC), Hormone Sensitive Prostate Cancer
Phase 3
Interventional 1,000 participants sought
University Hospitals Seidman Cancer Center at UH Avon Health Center — Avon, Ohio (7.7 mi)
· Sponsor: Pfizer
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
Solid Tumor, Non-Small-Cell Lung Cancer
Phase 1
Interventional 364 participants sought
University Hospitals - UH Cleveland Medical Center — Cleveland, Ohio (25.6 mi)
· Sponsor: Astellas Pharma Inc
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
Pulmonary Invasive Fungal Infections, Pulmonary Invasive Aspergillosis
N/A
Observational 400 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Arkansas Children's Hospital Research Institute
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Previously Treated Non-Small Cell Lung Cancer
Phase 2, Phase 3
Interventional 10,000 participants sought
UH Seidman Cancer Center at Saint John Medical Center — Westlake, Ohio (13.8 mi)
· Sponsor: SWOG Cancer Research Network
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Ulcerative Colitis
Phase 4
Interventional 65 participants sought
Gastro Intestinal Research Institute of Northern Ohio, LLC. — Westlake, Ohio (13.8 mi)
· Sponsor: Takeda
HCMR Re-Imaging Study
Hypertrophic Cardiomyopathy (HCM)
N/A
Observational 314 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Christopher Kramer
Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes
Peripheral Arterial Disease
N/A
Observational 14,000 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Baylor Research Institute
RESET System Pivotal Trial (Rev F)
Diabetes type2, Obesity
N/A
Interventional 264 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Morphic Medical Inc.
Study of Cytokine Release Syndrome Prophylaxis and Treatment With Siltuximab Prior to Epcoritamab
Non-Hodgkin Lymphoma, Cytokine Release Syndrome
Phase 1
Interventional 20 participants sought
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center — Cleveland, Ohio (25.6 mi)
· Sponsor: Taylor Brooks
Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery
Bleeding, Colorectal Disorders
Phase 2
Interventional 394 participants sought
Cleveland Clinic Fairview Hospital — Cleveland, Ohio (25.6 mi)
· Sponsor: Kristen Ban
A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission
Acute HIV Infection
Phase 2
Interventional 48 participants sought
2501, Case CRS — Cleveland, Ohio (25.6 mi)
· Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Multi-Center Clean Air Randomized Controlled Trial in COPD
Chronic Obstructive Pulmonary Disease (COPD)
Phase 3
Interventional 770 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: JHSPH Center for Clinical Trials
Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients
Irritability Associated With Autism Spectrum Disorder
Phase 3
Interventional 160 participants sought
Westlake Brain Health — Westlake, Ohio (13.8 mi)
· Sponsor: Intra-Cellular Therapies, Inc.
Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial
Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma
Phase 3
Interventional 1,524 participants sought
MetroHealth Medical Center — Cleveland, Ohio (25.6 mi)
· Sponsor: Alliance for Clinical Trials in Oncology
Zenith® Fenestrated+ Clinical Study
Aortic Aneurysm, Abdominal, Juxtarenal Aortic Aneurysm
N/A
Interventional 105 participants sought
Cleveland Clinic Foundation — Cleveland, Ohio (25.6 mi)
· Sponsor: Cook Research Incorporated