Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/OH/Lorain
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Lorain, OH

Studies commonly pay $75 to $4,500 per completed study

1,309 clinical trials are currently recruiting participants within 30 miles of Lorain. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,309studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Lorain right now

Top 25 of 1,309 recruiting studies, sorted by proximity — each links to its official registry page

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Carcinoma, Non-Small-Cell Lung Phase 1, Phase 2 Interventional 450 participants sought
Cleveland Clinic Main ( Site 0006) — Cleveland, Ohio (25.6 mi) · Sponsor: Merck Sharp & Dohme LLC

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Rainbow Babies and Childrens Hospital — Cleveland, Ohio (25.6 mi) · Sponsor: National Cancer Institute (NCI)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
University Hospitals of Cleveland ( Site 0155) — Cleveland, Ohio (25.6 mi) · Sponsor: Merck Sharp & Dohme LLC

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Cleveland, Ohio (25.6 mi) · Sponsor: Sameek Roychowdhury

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
University Hospitals Cleveland Medical Center — Cleveland, Ohio (25.6 mi) · Sponsor: Medtronic MiniMed, Inc.

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi) · Sponsor: Boehringer Ingelheim

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi) · Sponsor: Genentech, Inc.

A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF SHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS

Advanced Solid Tumors Phase 1, Phase 2 Interventional 83 participants sought
University Hospitals Cleveland Medical Center — Cleveland, Ohio (25.6 mi) · Sponsor: Jiangsu HengRui Medicine Co., Ltd.

Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD

Age-Related Macular Degeneration, Geographic Atrophy N/A Interventional 125 participants sought
Cleveland Clinic | Cole Eye Institute — Cleveland, Ohio (25.6 mi) · Sponsor: VisionCare, Inc.

Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis

Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting N/A Interventional 14 participants sought
Cleveland State University — Cleveland, Ohio (25.6 mi) · Sponsor: Cionic, Inc.

Study of AZD2389 Safety, Tolerability, and Pharmacodynamics in Adults With Steatotic Liver Disease and Advanced Fibrosis

Liver Fibrosis, Hepatic Cirrhosis Phase 2 Interventional 104 participants sought
Research Site — Westlake, Ohio (13.8 mi) · Sponsor: AstraZeneca

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Metastatic Castration Sensitive Prostate Cancer (mCSPC), Hormone Sensitive Prostate Cancer Phase 3 Interventional 1,000 participants sought
University Hospitals Seidman Cancer Center at UH Avon Health Center — Avon, Ohio (7.7 mi) · Sponsor: Pfizer

Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

Liver Cirrhoses, Portal Hypertension Related to Cirrhosis Phase 4 Interventional 70 participants sought
Cleveland Clinic Main Campus — Cleveland, Ohio (25.6 mi) · Sponsor: The Cleveland Clinic

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Solid Tumor, Non-Small-Cell Lung Cancer Phase 1 Interventional 364 participants sought
University Hospitals - UH Cleveland Medical Center — Cleveland, Ohio (25.6 mi) · Sponsor: Astellas Pharma Inc

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

Pulmonary Invasive Fungal Infections, Pulmonary Invasive Aspergillosis N/A Observational 400 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi) · Sponsor: Arkansas Children's Hospital Research Institute

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
UH Seidman Cancer Center at Saint John Medical Center — Westlake, Ohio (13.8 mi) · Sponsor: SWOG Cancer Research Network

A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

Myelodysplastic Syndrome, Acute Myeloid Leukemia Phase 1 Interventional 178 participants sought
University Hospitals Cleveland Medical Center — Cleveland, Ohio (25.6 mi) · Sponsor: Seagen, a wholly owned subsidiary of Pfizer

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Ulcerative Colitis Phase 4 Interventional 65 participants sought
Gastro Intestinal Research Institute of Northern Ohio, LLC. — Westlake, Ohio (13.8 mi) · Sponsor: Takeda

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Cleveland, Ohio (25.6 mi) · Sponsor: AstraZeneca
Actively enrolling

Studies you may be able to join near Lorain

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Google-rated

Top-rated research centers in Lorain

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Clinical Research Institute of Ohio

★ 5.0
850 Columbia Rd #200, Westlake, OH 44145
(440) 363-4000

Clinical Research Solutions - Cleveland, OH

★ 5.0
6900 Pearl Rd #305, Middleburg Heights, OH 44130
(440) 340-9010
"Outstanding staff. I look forward to seeing Cara and Brandon. Great experience!"
— steve allen, 5★

Cleveland Clinic - Lorain Family Health & Surgery Center

★ 3.8
5700 Cooper Foster Park Rd W, Lorain, OH 44053
(440) 616-6045
"5800 Cooper I’ve been trying to get documents signed so I can that I can return to work and they have ghosted me. Today makes 6 business days since I…"
— Sidney Thompson, 1★

Charak Center for Health and Wellness

★ 4.3 (332 reviews)
1530 W River Rd N First Floor, Elyria, OH 44035
(440) 324-5555
"So I booked an appointment to continue my meds that I'm on and start ADHD meds again and I was hopeful because they got me in so quickly. I was barel…"
— Taylor Lucas, 1★

Clinical Research Management

★ 5.0
1265 Ridge Rd Ste a, Hinckley, OH 44233
(330) 278-2343
"I am not sure what this place is but when I have time, I’d like to drive by and get some photos to add to this review with some details."
— Joseph Powell, 5★

C7Research

3762 Pearl Rd, Cleveland, OH 44109
(216) 282-7047

Paramount Medical Research

★ 5.0
18660 Bagley Rd #102B, Cleveland, OH 44130
(440) 826-0742

Insight Clinical Trials

★ 4.7
4801 Acorn Dr, Independence, OH 44131
(216) 526-1843
"I love the staff very welcoming"
— El-Rico A Dejesus, 5★

Velocity Clinical Research

★ 4.5
3619 Park E Dr Ste 300, Beachwood, OH 44122
(216) 682-0320

Clinical trials in Lorain: what's recruiting

The Lorain area currently has 1,309 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Lorain, the most active research areas are:

  • Cancer & Oncology11 studies
  • Diabetes & Metabolism4 studies
  • Immune & Skin3 studies
  • Liver & Kidney3 studies
  • Heart & Vascular2 studies

Every listing shows the study phase, the recruiting site and its distance from Lorain, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Lorain

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Lorain participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Lorain?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Lorain, OH?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Lorain?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Lorain typically complete one or two studies per year.

Paid clinical trials near Lorain

Other metros within reach

By condition

Eligibility and exclusions, condition by condition

More of OH

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