Live from the NIH registry
Studies recruiting near Lorain right now
Top 25 of 1,309 recruiting studies, sorted by proximity — each links to its official registry page
KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)
Carcinoma, Non-Small-Cell Lung
Phase 1, Phase 2
Interventional 450 participants sought
Cleveland Clinic Main ( Site 0006) — Cleveland, Ohio (25.6 mi)
· Sponsor: Merck Sharp & Dohme LLC
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
B Acute Lymphoblastic Leukemia
Phase 2
Interventional 222 participants sought
Rainbow Babies and Childrens Hospital — Cleveland, Ohio (25.6 mi)
· Sponsor: National Cancer Institute (NCI)
Treatment of Moderate to Severe Refractory Crohn's Disease
Crohns Disease
Phase 1, Phase 2
Interventional 39 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Tr1X, Inc.
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
Lymphoma, Large B-Cell, Diffuse
Phase 2
Interventional 594 participants sought
University Hospitals of Cleveland ( Site 0155) — Cleveland, Ohio (25.6 mi)
· Sponsor: Merck Sharp & Dohme LLC
A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations
Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma
Phase 2
Interventional 40 participants sought
Ohio State University-Telemedicine — Cleveland, Ohio (25.6 mi)
· Sponsor: Sameek Roychowdhury
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
N/A
Interventional 400 participants sought
University Hospitals Cleveland Medical Center — Cleveland, Ohio (25.6 mi)
· Sponsor: Medtronic MiniMed, Inc.
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
Diabetic Macular Edema
Phase 1, Phase 2
Interventional 49 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Boehringer Ingelheim
A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)
Neovascular Age-related Macular Degeneration
Phase 4
Interventional 188 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Genentech, Inc.
A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF SHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS
Advanced Solid Tumors
Phase 1, Phase 2
Interventional 83 participants sought
University Hospitals Cleveland Medical Center — Cleveland, Ohio (25.6 mi)
· Sponsor: Jiangsu HengRui Medicine Co., Ltd.
Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD
Age-Related Macular Degeneration, Geographic Atrophy
N/A
Interventional 125 participants sought
Cleveland Clinic | Cole Eye Institute — Cleveland, Ohio (25.6 mi)
· Sponsor: VisionCare, Inc.
Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
N/A
Interventional 14 participants sought
Cleveland State University — Cleveland, Ohio (25.6 mi)
· Sponsor: Cionic, Inc.
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation
Atrial Fibrillation, Obesity
Phase 2
Interventional 100 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: The Cleveland Clinic
Study of AZD2389 Safety, Tolerability, and Pharmacodynamics in Adults With Steatotic Liver Disease and Advanced Fibrosis
Liver Fibrosis, Hepatic Cirrhosis
Phase 2
Interventional 104 participants sought
Research Site — Westlake, Ohio (13.8 mi)
· Sponsor: AstraZeneca
RA-PRO PRAGMATIC TRIAL
Rheumatoid Arthritis
Phase 3
Interventional 924 participants sought
University Hospital Cleveland Medical Ctr — Cleveland, Ohio (25.6 mi)
· Sponsor: University of Alabama at Birmingham
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Bladder Carcinoma, Ureter Carcinoma
N/A
Observational 2,020 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Guardant Health, Inc.
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Metastatic Castration Sensitive Prostate Cancer (mCSPC), Hormone Sensitive Prostate Cancer
Phase 3
Interventional 1,000 participants sought
University Hospitals Seidman Cancer Center at UH Avon Health Center — Avon, Ohio (7.7 mi)
· Sponsor: Pfizer
Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease
Liver Cirrhoses, Portal Hypertension Related to Cirrhosis
Phase 4
Interventional 70 participants sought
Cleveland Clinic Main Campus — Cleveland, Ohio (25.6 mi)
· Sponsor: The Cleveland Clinic
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
Solid Tumor, Non-Small-Cell Lung Cancer
Phase 1
Interventional 364 participants sought
University Hospitals - UH Cleveland Medical Center — Cleveland, Ohio (25.6 mi)
· Sponsor: Astellas Pharma Inc
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
Pulmonary Invasive Fungal Infections, Pulmonary Invasive Aspergillosis
N/A
Observational 400 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Arkansas Children's Hospital Research Institute
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Previously Treated Non-Small Cell Lung Cancer
Phase 2, Phase 3
Interventional 10,000 participants sought
UH Seidman Cancer Center at Saint John Medical Center — Westlake, Ohio (13.8 mi)
· Sponsor: SWOG Cancer Research Network
A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies
Myelodysplastic Syndrome, Acute Myeloid Leukemia
Phase 1
Interventional 178 participants sought
University Hospitals Cleveland Medical Center — Cleveland, Ohio (25.6 mi)
· Sponsor: Seagen, a wholly owned subsidiary of Pfizer
Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy
Amblyopia, Strabismus
N/A
Observational 150 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: The Cleveland Clinic
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Ulcerative Colitis
Phase 4
Interventional 65 participants sought
Gastro Intestinal Research Institute of Northern Ohio, LLC. — Westlake, Ohio (13.8 mi)
· Sponsor: Takeda
A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy
Locally Advanced Head and Neck Squamous Cell Carcinoma
Phase 3
Interventional 1,145 participants sought
Research Site — Cleveland, Ohio (25.6 mi)
· Sponsor: AstraZeneca
Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes
Peripheral Arterial Disease
N/A
Observational 14,000 participants sought
Cleveland Clinic — Cleveland, Ohio (25.6 mi)
· Sponsor: Baylor Research Institute