Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/OH/Youngstown
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Youngstown, OH

Studies commonly pay $75 to $4,500 per completed study

87 clinical trials are currently recruiting participants within 30 miles of Youngstown. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

87studies recruiting
3+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Youngstown right now

Top 25 of 87 recruiting studies, sorted by proximity — each links to its official registry page

Effects of Amylopectin Chromium Blend on Whole-Body Protein Kinetics and Glucose in Peri/Post-Menopausal Women

Glucose Monitoring, Continuous, Whole Body Protein Metabolism N/A Interventional 60 participants sought
The Center for Applied Health Sciences — Canfield, Ohio (7.9 mi) · Sponsor: Nutrition 21, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07402382)

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

Psoriasis, Overweight or Obesity Phase 4 Interventional 200 participants sought
Optima Research - Boardman — Boardman, Ohio (5.3 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT06857942)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05561387)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,209 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05946213)

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

Multiple conditions Phase 2 Interventional 98 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06532279)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT01810913)

Mobile Health for Adherence in Breast Cancer Patients

Anatomic Stage IV Breast Cancer AJCC v8, Breast Carcinoma N/A Interventional 410 participants sought
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT06112613)

Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

Resectable Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8 Phase 3 Interventional 1,100 participants sought
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06632327)

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 Phase 3 Interventional 1,524 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06876714)

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Phase 3 Interventional 247 participants sought
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04269902)

Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery

Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v6 and v7, Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7 Phase 2 Interventional 82 participants sought
UPMC Jameson — New Castle, Pennsylvania (16.9 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03493425)

Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body

Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion N/A Observational 150 participants sought
Mercy Health Youngstown — Youngstown, Ohio (0.2 mi) · Sponsor: Bayer
See eligibility & contact on ClinicalTrials.gov (NCT04142437)

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Extensive Stage Lung Small Cell Carcinoma Phase 2, Phase 3 Interventional 138 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04402788)

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma Phase 2, Phase 3 Interventional 224 participants sought
UPMC Hillman Cancer Center - New Castle — New Castle, Pennsylvania (16.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06203600)

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Breast Cancer, Early Breast Cancer Phase 3 Interventional 5,500 participants sought
Research Site — Youngstown, Ohio (0.2 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT05952557)

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Malignancy N/A Observational 240 participants sought
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04242095)

A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis

Moderate to Severe Atopic Dermatitis Phase 1 Interventional 149 participants sought
Sitryx Clinical Site — Boardman, Ohio (5.3 mi) · Sponsor: Sitryx Therapeutics Ltd
See eligibility & contact on ClinicalTrials.gov (NCT07558668)

A Study Evaluating BFB759 in Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa (HS) Phase 2, Phase 3 Interventional 210 participants sought
Optima Research - Boardman — Boardman, Ohio (5.3 mi) · Sponsor: Bluefin Biomedicine, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07287644)

Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)

Pruritus Phase 3 Interventional 284 participants sought
Optima Research - Boardman- Site Number : 8400039 — Boardman, Ohio (5.3 mi) · Sponsor: Sanofi
See eligibility & contact on ClinicalTrials.gov (NCT05263206)

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

Metastatic Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8 Phase 2 Interventional 240 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05327686)
Actively enrolling

Studies you may be able to join near Youngstown

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for severe chronic itching

Enrolling adults aged 18 to 90 who have had chronic itching for six months or longer. Not open to itching caused by atopic dermatitis, psoriasis, chronic kidney disease, notalgia paresthetica or medication, nor to people with an autoimmune condition such as lupus, Crohn's disease, ulcerative colitis or rheumatoid arthritis.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Youngstown

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

The Center for Applied Health Sciences

★ 5.0
6570 Seville Dr, Canfield, OH 44406
(330) 926-6927

Integrity First Clinical Trials

400 E Main St Ste M3, Canfield, OH 44406
(330) 234-9416

Optima Research

1039 Boardman-Canfield Rd Bldg B, Suite B, Boardman, OH 44512
(330) 422-3234

Clinical trials in Youngstown: what's recruiting

The Youngstown area currently has 87 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Youngstown, the most active research areas are:

  • Cancer & Oncology18 studies
  • Immune & Skin2 studies
  • Diabetes & Metabolism1 studies
  • Brain & Mental Health1 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from Youngstown, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Youngstown

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Youngstown participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Youngstown?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Youngstown, OH?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Youngstown?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Youngstown?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Youngstown.

Paid clinical trials near Youngstown

Other metros within reach

Canton, OH307 Akron, OH394 Pittsburgh, PA1,237 Cleveland, OH1,409 Erie, PA88 Lorain, OH1,304 Buffalo, NY513 Columbus, OH1,340

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Youngstown Severe Chronic Pruritus in Youngstown Bladder Issues Due To Spinal Cord Injury in Youngstown All conditions

More of OH

Cleveland1,409 Columbus1,340 Lorain1,304 Cincinnati1,131 Akron394 Dayton310 Canton307 Toledo208

New paid studies open every week

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