Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/OH/Youngstown
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Youngstown, OH

Studies commonly pay $75 to $4,500 per completed study

82 clinical trials are currently recruiting participants within 30 miles of Youngstown. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

82studies recruiting
3+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Youngstown right now

Top 25 of 82 recruiting studies, sorted by proximity — each links to its official registry page

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 189 participants sought
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT02734537)

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Malignancy N/A Observational 240 participants sought
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04242095)

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma, Stage I Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8 Phase 3 Interventional 228 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06992427)

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

Metastatic Salivary Gland Carcinoma, Recurrent Salivary Gland Carcinoma Phase 2 Interventional 146 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05408845)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05561387)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,209 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05946213)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT01810913)

Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Hip

Osteoarthritis Phase 2 Interventional 4,000 participants sought
VivaTech International, Inc. — Grove City, Pennsylvania (29.3 mi) · Sponsor: VivaTech International, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT02844764)

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma Phase 2 Interventional 81 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05112601)

Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

Resectable Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8 Phase 3 Interventional 1,100 participants sought
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06632327)

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Liver Phase 3 Interventional 408 participants sought
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT05863195)

Distance-Based Exercise to Preserve Function and Prevent Disability

Localized Malignant Solid Neoplasm, Anal Cancer N/A Interventional 104 participants sought
UPMC Hillman Cancer Center - New Castle — New Castle, Pennsylvania (16.9 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT07059884)

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

Colorectal Cancer, CRC (Colorectal Cancer) Phase 2 Interventional 136 participants sought
NGM Clinical Study Site — Youngstown, Ohio (0.2 mi) · Sponsor: NGM Biopharmaceuticals, Inc
See eligibility & contact on ClinicalTrials.gov (NCT07033026)

A Trial to Study the Effects of Ginseng and Cordyceps on Aerobic Capacity, Lactate Kinetics, and Nitric Oxide

Healthy Subjects With Low Energy Levels N/A Interventional 75 participants sought
The Center for Applied Health Sciences — Canfield, Ohio (7.9 mi) · Sponsor: Applied Food Sciences Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07729943)

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Advanced Malignant Solid Neoplasm, Anatomic Stage III Breast Cancer AJCC v8 Phase 2 Interventional 2,900 participants sought
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564377)

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma Phase 3 Interventional 364 participants sought
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT04510597)

Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery

Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v6 and v7, Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7 Phase 2 Interventional 82 participants sought
UPMC Jameson — New Castle, Pennsylvania (16.9 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03493425)

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Breast Cancer, Early Breast Cancer Phase 3 Interventional 5,500 participants sought
Research Site — Youngstown, Ohio (0.2 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT05952557)

The Lilac Device Trial - IMPACT: A Clinical Investigation on IMproving Peripheral Neuropathy Induced by Chemotherapy With Advanced Compression Technology - A Safety and Efficacy Study

Chemotherapy Induced Peripheral Neuropathy (CIPN) N/A Interventional 142 participants sought
Mercy Health St. Elizabeth Hospital — Youngstown, Ohio (0.2 mi) · Sponsor: Luminate Medical, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07142304)

Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers

Diabetic Foot Ulcer (DFU), Chronic Foot Ulcers N/A Interventional 240 participants sought
Lower Extremity Institute of Research and Therapy — Boardman, Ohio (5.3 mi) · Sponsor: Tides Medical
See eligibility & contact on ClinicalTrials.gov (NCT06681428)

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Phase 2 Interventional 180 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07195734)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania (11.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)
Actively enrolling

Studies you may be able to join near Youngstown

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for severe chronic itching

Enrolling adults aged 18 to 90 who have had chronic itching for six months or longer. Not open to itching caused by atopic dermatitis, psoriasis, chronic kidney disease, notalgia paresthetica or medication, nor to people with an autoimmune condition such as lupus, Crohn's disease, ulcerative colitis or rheumatoid arthritis.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Youngstown

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

The Center for Applied Health Sciences

★ 5.0
6570 Seville Dr, Canfield, OH 44406
(330) 926-6927

Integrity First Clinical Trials

400 E Main St Ste M3, Canfield, OH 44406
(330) 234-9416

Optima Research

1039 Boardman-Canfield Rd Bldg B, Suite B, Boardman, OH 44512
(330) 422-3234

Clinical trials in Youngstown: what's recruiting

The Youngstown area currently has 82 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Youngstown, the most active research areas are:

  • Cancer & Oncology18 studies
  • Liver & Kidney4 studies
  • Immune & Skin2 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Youngstown, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Youngstown

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Youngstown participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Youngstown?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Youngstown, OH?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Youngstown?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Youngstown?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Youngstown.

Paid clinical trials near Youngstown

Other metros within reach

Canton, OH304 Akron, OH394 Pittsburgh, PA1,232 Cleveland, OH1,413 Erie, PA89 Lorain, OH1,309 Buffalo, NY516 Columbus, OH1,345

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Youngstown Severe Chronic Pruritus in Youngstown Bladder Issues Due To Spinal Cord Injury in Youngstown All conditions

More of OH

Cleveland1,413 Columbus1,345 Lorain1,309 Cincinnati1,127 Akron394 Dayton310 Canton304 Toledo211

New paid studies open every week

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