Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NY/Buffalo
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Buffalo, NY

Studies commonly pay $75 to $4,500 per completed study

516 clinical trials are currently recruiting participants within 30 miles of Buffalo. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

516studies recruiting
9+research centers nearby
3condition categories
Live from the NIH registry

Studies recruiting near Buffalo right now

Top 25 of 516 recruiting studies, sorted by proximity — each links to its official registry page

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Roswell Park Cancer Institute — Buffalo, New York (1.8 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Roswell Park Cancer Institute — Buffalo, New York (1.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
Erie County Medical Center ( Site 0175) — Buffalo, New York (1.8 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University Telemedicine — Buffalo, New York (1.8 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer

Carcinoma, Non-small-Cell Lung Phase 1 Interventional 126 participants sought
Roswell Park Comprehensive Cancer Center — Buffalo, New York (1.8 mi) · Sponsor: Johnson & Johnson Enterprise Innovation Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06116786)

A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

Generalized Myasthenia Gravis Phase 3 Interventional 180 participants sought
Dent Neurological Institute — Buffalo, New York (1.8 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06744920)

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Chronic Migraine Phase 3 Interventional 420 participants sought
Dent Neurologic Institute - Amherst /ID# 270260 — Amherst, New York (5.8 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06810505)

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Percutaneous Coronary Intervention, Peripheral Endovascular Intervention Phase 4 Interventional 6,000 participants sought
Sisters of Charity Hospital — Buffalo, New York (1.8 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT06909565)

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

Aortic Valve Insufficiency, Aortic Valve Stenosis N/A Interventional 200 participants sought
University of Buffalo — Buffalo, New York (1.8 mi) · Sponsor: Edwards Lifesciences
See eligibility & contact on ClinicalTrials.gov (NCT05172973)

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

Cystic Fibrosis N/A Observational 400 participants sought
The Cystic Fibrosis Center of Western New York — Buffalo, New York (1.8 mi) · Sponsor: Nicole Hamblett
See eligibility & contact on ClinicalTrials.gov (NCT06504589)

Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems

Peripheral Neuropathies, Peripheral Neuropathy Due to Chemotherapy N/A Interventional 200 participants sought
Dent Neurologic Institute — Amherst, New York (5.8 mi) · Sponsor: RxFunction Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06959277)

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma Phase 3 Interventional 1,524 participants sought
Roswell Park Cancer Institute — Buffalo, New York (1.8 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT07200830)

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Phase 3 Interventional 1,200 participants sought
Roswell Park Cancer Institute ( Site 0023) — Buffalo, New York (1.8 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06136559)

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Advanced Solid Tumor, Melanoma Phase 2 Interventional 740 participants sought
Roswell Park Cancer Institute IDS — Buffalo, New York (1.8 mi) · Sponsor: Daiichi Sankyo
See eligibility & contact on ClinicalTrials.gov (NCT06172478)

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism Phase 2, Phase 3 Interventional 2,800 participants sought
Research Foundation of SUNY - University of Buffalo /ID# 261019 — Buffalo, New York (1.8 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06345339)

Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

Viral Pneumonia Phase 2 Interventional 550 participants sought
VA Western New York Healthcare system — Buffalo, New York (1.8 mi) · Sponsor: Synairgen Research Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT06999603)

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

Acute Myeloid Leukemia (AML) Phase 3 Interventional 1,300 participants sought
State University of New York at Buffalo — Buffalo, New York (1.8 mi) · Sponsor: Kura Oncology, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07007312)

Lamivudine in Combination With Chemoimmunotherapy for the Treatment of Extensive Stage Small Cell Lung Cancer

Extensive Stage Lung Small Cell Carcinoma Phase 2 Interventional 28 participants sought
Roswell Park Cancer Institute — Buffalo, New York (1.8 mi) · Sponsor: Roswell Park Cancer Institute
See eligibility & contact on ClinicalTrials.gov (NCT04696575)

PUSH-IT Continuing Enteral Feeds for Tracheostomy

Tracheostomy Complication, Critical Illness N/A Interventional 200 participants sought
Erie County Medical Center (University at Buffalo) — Buffalo, New York (1.8 mi) · Sponsor: State University of New York at Buffalo
See eligibility & contact on ClinicalTrials.gov (NCT05906472)

Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy

Urothelial Cancer Phase 2, Phase 3 Interventional 470 participants sought
Local Institution - 0248 — Buffalo, New York (1.8 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT07106762)
Actively enrolling

Studies you may be able to join near Buffalo

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Buffalo

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Clinical Translational Research Center - University at Buffalo

★ 5.0
875 Ellicott St, Buffalo, NY 14203
(716) 645-2000

Circuit Clinical

★ 3.3
1 W Seneca St 24th Floor, Buffalo, NY 14203
(888) 732-3990
"This is for Margate. When you do a Clinical Research Study with Circuit Clinical you DO NOT sign a Confidentiality agreement. It is called a Consent …"
— Karen, 5★

Scott Bieler Clinical Sciences Center

★ 4.8 (26 reviews)
128 Carlton St, Buffalo, NY 14203
(716) 845-2300
"The staff at supportive care clinic are fantastic. I felt comfortable and relaxed coming to the clinic.<br>My therapist is wonderful and has provide…"
— Stephen Uram, 5★

Center for Genetics and Pharmacology

★ 4.8
658 Virginia St, Buffalo, NY 14263
(877) 275-7724
"A top notch facility for cancer research. Part of Roswell Park Comprehensive Cancer Center, Buffalo, New York."
— Uchechukwu Brian Eziagu, 5★

CCRG Research

★ 5.0
1083 Delaware Ave, Buffalo, NY 14209
(716) 833-9300
"I took part in one of their research studies. The staff was very friendly, helpful, and attentive. I was impressed by the efficiency of the experienc…"
— Peter Wilson, 5★

Canon Stroke & Vascular Research Center

★ 5.0
875 Ellicott St, Buffalo, NY 14203
(716) 829-5400

Center For Computational Research

★ 5.0
701 Ellicott St, Buffalo, NY 14203
(716) 645-6500
"Super computer is awesome and well maintained."
— Anudeep Reddy, 5★

Buffalo Neuroimaging Analysis Center

★ 5.0
Suite 450, 77 Goodell St, Buffalo, NY 14203
(833) 914-4967

Research Institute On Addictions

★ 5.0
Research Institute on Addictions, 1021 Main St, Buffalo, NY 14203
(716) 887-2566
"5 star place in my humble opinion"
— collin fitzy, 5★

Clinical trials in Buffalo: what's recruiting

The Buffalo area currently has 516 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Buffalo, the most active research areas are:

  • Cancer & Oncology13 studies
  • Heart & Vascular1 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Buffalo, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Buffalo

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Buffalo participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Buffalo pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Buffalo safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Buffalo?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Buffalo typically complete one or two studies per year.

Paid clinical trials near Buffalo

Other metros within reach

Rochester, NY471 Erie, PA89 Youngstown, OH82 Pittsburgh, PA1,232 Syracuse, NY249 Binghamton, NY21 Cleveland, OH1,413 Akron, OH394

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Buffalo Bladder Issues Due To Spinal Cord Injury in Buffalo All conditions

More of NY

Staten Island4,271 Brooklyn4,269 New York4,206 Manhattan4,198 Bronx4,178 Queens4,161 Yonkers4,153 Rochester471 Syracuse249 Albany197 Poughkeepsie77

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