Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NY/Buffalo
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Buffalo, NY

Studies commonly pay $75 to $4,500 per completed study

517 clinical trials are currently recruiting participants within 30 miles of Buffalo. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

517studies recruiting
9+research centers nearby
3condition categories
Live from the NIH registry

Studies recruiting near Buffalo right now

Top 25 of 517 recruiting studies, sorted by proximity — each links to its official registry page

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Roswell Park Cancer Institute — Buffalo, New York (1.8 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma Phase 2 Interventional 81 participants sought
Roswell Park Cancer Institute — Buffalo, New York (1.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05112601)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Roswell Park Cancer Institute — Buffalo, New York (1.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)

Pediatric Cancer N/A Observational 35 participants sought
Roswell Park Comprehensive Cancer Center — Buffalo, New York (1.8 mi) · Sponsor: H. Lee Moffitt Cancer Center and Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT06423950)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
Erie County Medical Center ( Site 0175) — Buffalo, New York (1.8 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University Telemedicine — Buffalo, New York (1.8 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease

Aortoiliac Occlusive Disease, Peripheral Arterial Disease N/A Interventional 244 participants sought
Trinity Medical Center — Buffalo, New York (1.8 mi) · Sponsor: W.L.Gore & Associates
See eligibility & contact on ClinicalTrials.gov (NCT05811364)

A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer

Carcinoma, Non-small-Cell Lung Phase 1 Interventional 126 participants sought
Roswell Park Comprehensive Cancer Center — Buffalo, New York (1.8 mi) · Sponsor: Johnson & Johnson Enterprise Innovation Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06116786)

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

Leukemia, Leukemia, Myeloid Phase 1 Interventional 170 participants sought
Roswell Park Cancer Institute — Buffalo, New York (1.8 mi) · Sponsor: BlossomHill Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06501196)

A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

Generalized Myasthenia Gravis Phase 3 Interventional 180 participants sought
Dent Neurological Institute — Buffalo, New York (1.8 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06744920)

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Percutaneous Coronary Intervention, Peripheral Endovascular Intervention Phase 4 Interventional 6,000 participants sought
Sisters of Charity Hospital — Buffalo, New York (1.8 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT06909565)

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

Aortic Valve Insufficiency, Aortic Valve Stenosis N/A Interventional 200 participants sought
University of Buffalo — Buffalo, New York (1.8 mi) · Sponsor: Edwards Lifesciences
See eligibility & contact on ClinicalTrials.gov (NCT05172973)

Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems

Peripheral Neuropathies, Peripheral Neuropathy Due to Chemotherapy N/A Interventional 200 participants sought
Dent Neurologic Institute — Amherst, New York (5.8 mi) · Sponsor: RxFunction Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06959277)

Robotic Minimally Invasive Inguinal Hernia Repair Post-Market Clinical Study With the DEXTER Robotic System

Inguinal Hernia Repair N/A Observational 140 participants sought
Northtowns Ambulatory Surgical Center (NASC) — Buffalo, New York (1.8 mi) · Sponsor: Distalmotion SA
See eligibility & contact on ClinicalTrials.gov (NCT07181876)

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

Large B-cell Lymphoma, Lymphoma, B-Cell Phase 3 Interventional 400 participants sought
Roswell Park Comprehensive Cancer Center — Buffalo, New York (1.8 mi) · Sponsor: Lyell Immunopharma, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07188558)

Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

Failed or Difficult Intubation, Sequela, Intubation; Difficult N/A Observational 150,000 participants sought
Oishei Children's Hospital — Buffalo, New York (1.8 mi) · Sponsor: Children's Hospital of Philadelphia
See eligibility & contact on ClinicalTrials.gov (NCT02493478)

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

Low Grade Serous Ovarian Cancer Phase 3 Interventional 270 participants sought
Roswell Park Cancer Institute — Buffalo, New York (1.8 mi) · Sponsor: Verastem, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06072781)

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Advanced Solid Tumor, Melanoma Phase 2 Interventional 740 participants sought
Roswell Park Cancer Institute IDS — Buffalo, New York (1.8 mi) · Sponsor: Daiichi Sankyo
See eligibility & contact on ClinicalTrials.gov (NCT06172478)
Actively enrolling

Studies you may be able to join near Buffalo

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Buffalo

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Clinical Translational Research Center - University at Buffalo

★ 5.0
875 Ellicott St, Buffalo, NY 14203
(716) 645-2000

Circuit Clinical

★ 3.3
1 W Seneca St 24th Floor, Buffalo, NY 14203
(888) 732-3990
"This is for Margate. When you do a Clinical Research Study with Circuit Clinical you DO NOT sign a Confidentiality agreement. It is called a Consent …"
— Karen, 5★

Scott Bieler Clinical Sciences Center

★ 4.8 (26 reviews)
128 Carlton St, Buffalo, NY 14203
(716) 845-2300
"The staff at supportive care clinic are fantastic. I felt comfortable and relaxed coming to the clinic.<br>My therapist is wonderful and has provide…"
— Stephen Uram, 5★

Center for Genetics and Pharmacology

★ 4.8
658 Virginia St, Buffalo, NY 14263
(877) 275-7724
"A top notch facility for cancer research. Part of Roswell Park Comprehensive Cancer Center, Buffalo, New York."
— Uchechukwu Brian Eziagu, 5★

CCRG Research

★ 5.0
1083 Delaware Ave, Buffalo, NY 14209
(716) 833-9300
"I took part in one of their research studies. The staff was very friendly, helpful, and attentive. I was impressed by the efficiency of the experienc…"
— Peter Wilson, 5★

Canon Stroke & Vascular Research Center

★ 5.0
875 Ellicott St, Buffalo, NY 14203
(716) 829-5400

Center For Computational Research

★ 5.0
701 Ellicott St, Buffalo, NY 14203
(716) 645-6500
"Super computer is awesome and well maintained."
— Anudeep Reddy, 5★

Buffalo Neuroimaging Analysis Center

★ 5.0
Suite 450, 77 Goodell St, Buffalo, NY 14203
(833) 914-4967

Research Institute On Addictions

★ 5.0
Research Institute on Addictions, 1021 Main St, Buffalo, NY 14203
(716) 887-2566
"5 star place in my humble opinion"
— collin fitzy, 5★

Clinical trials in Buffalo: what's recruiting

The Buffalo area currently has 517 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Buffalo, the most active research areas are:

  • Cancer & Oncology13 studies
  • Heart & Vascular1 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Buffalo, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Buffalo

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Buffalo participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Buffalo pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Buffalo safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Buffalo?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Buffalo typically complete one or two studies per year.

Paid clinical trials near Buffalo

Other metros within reach

Rochester, NY473 Erie, PA88 Youngstown, OH81 Pittsburgh, PA1,234 Syracuse, NY242 Binghamton, NY20 Cleveland, OH1,406 Akron, OH388

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Buffalo Bladder Issues Due To Spinal Cord Injury in Buffalo All conditions

More of NY

Staten Island4,282 Brooklyn4,279 New York4,211 Manhattan4,207 Bronx4,188 Queens4,172 Yonkers4,161 Rochester473 Syracuse242 Albany201 Poughkeepsie78

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