Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/PA/Erie
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Erie, PA

Studies commonly pay $75 to $4,500 per completed study

89 clinical trials are currently recruiting participants within 30 miles of Erie. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

89studies recruiting
4+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Erie right now

Top 25 of 89 recruiting studies, sorted by proximity — each links to its official registry page

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 189 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT02734537)

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Malignant Female Reproductive System Neoplasm, Malignant Solid Neoplasm Phase 2 Interventional 70 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06126276)

Study to Evaluate the Safety of CG-P5 Peptide Eye Drops in Patients Diagnosed With Age-related Wet Macular Degeneration

Age-related Wet Macular Degeneration Phase 1 Interventional 45 participants sought
CBCC Global Research Site:002 — Erie, Pennsylvania (1.1 mi) · Sponsor: Caregen Co. Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT06132035)

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma, Stage I Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8 Phase 3 Interventional 228 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06992427)

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

Metastatic Salivary Gland Carcinoma, Recurrent Salivary Gland Carcinoma Phase 2 Interventional 146 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05408845)

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma Phase 3 Interventional 255 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07198074)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,209 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05946213)

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Stage I Breast Cancer Phase 3 Interventional 1,670 participants sought
Saint Vincent Hospital — Erie, Pennsylvania (1.1 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04852887)

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma Phase 2 Interventional 81 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05112601)

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Adenocarcinoma Phase 3 Interventional 1,260 participants sought
Saint Vincent Hospital — Erie, Pennsylvania (1.1 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06931340)

A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine

Lyme Disease Phase 3 Interventional 1,712 participants sought
Allegheny Health and Wellness Pavilion — Erie, Pennsylvania (1.1 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07500506)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT01810913)

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD Phase 3 Interventional 284 participants sought
Adverum Clinical Site 181 — Erie, Pennsylvania (1.1 mi) · Sponsor: Adverum Biotechnologies, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07482176)

A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea

Functional Hypothalamic Amenorrhea (FHA) Phase 2 Interventional 34 participants sought
OBGYN Associates of Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07235917)

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

Macular Degeneration, Age-Related Macular Degeneration Phase 2, Phase 3 Interventional 960 participants sought
Erie Retina Research — Erie, Pennsylvania (1.1 mi) · Sponsor: EyeBiotech Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT07496567)

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Liver Phase 3 Interventional 408 participants sought
Saint Vincent Hospital — Erie, Pennsylvania (1.1 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT05863195)

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Advanced Malignant Solid Neoplasm, Anatomic Stage III Breast Cancer AJCC v8 Phase 2 Interventional 2,900 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564377)

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma Phase 3 Interventional 364 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT04510597)

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Endometrial Carcinoma, Endometrial Clear Cell Adenocarcinoma Phase 3 Interventional 360 participants sought
Saint Vincent Hospital — Erie, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05256225)

A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

Uterine Fibroids, Endometriosis Phase 3 Interventional 1,000 participants sought
Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: Sumitomo Pharma Switzerland GmbH
See eligibility & contact on ClinicalTrials.gov (NCT05862272)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Locally Advanced Urothelial Carcinoma, Metastatic Urothelial Carcinoma Phase 3 Interventional 320 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06524544)

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Phase 2 Interventional 180 participants sought
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07195734)
Actively enrolling

Studies you may be able to join near Erie

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Erie

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Square-1 Clinical Research

2221-A Ebco Dr, Erie, PA 16506
(814) 838-8724

Erie Retina Research

★ 4.8
2005 W 8th St, Erie, PA 16505
(814) 200-9152
"Dr. Almeida is always awesome!"
— Joe Ropelewski, 5★

Susan Hirt Hagen Center for Community Outreach, Research, and Evaluation (CORE)

★ 5.0
5343 Station Rd, Erie, PA 16510
(814) 898-6297
"Great tour today! Props to Hannah, our guide"
— Jeanie Sing, 5★

Great Lakes Medical Research

138 E Main St, Westfield, NY 14787
(716) 326-4890

Clinical trials in Erie: what's recruiting

The Erie area currently has 89 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Erie, the most active research areas are:

  • Cancer & Oncology16 studies
  • Heart & Vascular3 studies
  • Liver & Kidney3 studies
  • Lungs & Breathing1 studies

Every listing shows the study phase, the recruiting site and its distance from Erie, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Erie

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Erie participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Erie?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Erie safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Erie?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Erie typically complete one or two studies per year.

Paid clinical trials near Erie

Other metros within reach

Youngstown, OH82 Buffalo, NY516 Pittsburgh, PA1,232 Cleveland, OH1,413 Akron, OH394 Canton, OH304 Lorain, OH1,309 Rochester, NY471

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Erie Bladder Issues Due To Spinal Cord Injury in Erie All conditions

More of PA

Philadelphia2,177 Pittsburgh1,232 York447 Lancaster431 Harrisburg402 Reading280 Allentown234 Scranton99

New paid studies open every week

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