Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/PA/Philadelphia
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Philadelphia, PA

Studies commonly pay $75 to $4,500 per completed study

2,171 clinical trials are currently recruiting participants within 30 miles of Philadelphia. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

2,171studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Philadelphia right now

Top 25 of 2,171 recruiting studies, sorted by proximity — each links to its official registry page

CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT

Acute Leukemia, Acute Myeloid Leukemia N/A Interventional 50 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Children's Hospital of Philadelphia
See eligibility & contact on ClinicalTrials.gov (NCT03810196)

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

High Grade Glioma, Diffuse Intrinsic Pontine Glioma Phase 2 Interventional 120 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Nationwide Children's Hospital
See eligibility & contact on ClinicalTrials.gov (NCT05096481)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
Abramson Cancer Center and Perelman Center for Advanced Medicine ( Site 0131) — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

Neuroblastoma Recurrent Phase 2 Interventional 54 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: St. Jude Children's Research Hospital
See eligibility & contact on ClinicalTrials.gov (NCT07085338)

CART123 Cells With or Without Ruxolitinib in Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML) Phase 1 Interventional 30 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Stephan Grupp MD PhD
See eligibility & contact on ClinicalTrials.gov (NCT07464951)

One-Time DNA Study for Vasculitis

Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss), Giant Cell Arteritis N/A Observational 1,000 participants sought
University of Pennsylvania — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: University of Pennsylvania
See eligibility & contact on ClinicalTrials.gov (NCT01241305)

Adaptive Radiation for Abdominopelvic Metastases

Neoplasm - Soft Tissue Pelvis Malignant Secondary, Malignant Neoplasm of Stomach Phase 1 Interventional 30 participants sought
Fox Chase Cancer Center — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Fox Chase Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT05880667)

A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)

PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM) Phase 1 Interventional 9 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Rocket Pharmaceuticals Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05885412)

Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial

Crohn Disease N/A Interventional 60 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Seattle Children's Hospital
See eligibility & contact on ClinicalTrials.gov (NCT06216899)

Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy

Chronic Graft-versus-host Disease (cGVHD) Phase 2 Interventional 120 participants sought
Fox Chase Cancer Center — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: H. Lee Moffitt Cancer Center and Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT06660355)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Lymphoma, Non-Hodgkin, Multiple Myeloma Phase 2 Interventional 4,200 participants sought
Fox Chase Cancer Center — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: American Society of Clinical Oncology
See eligibility & contact on ClinicalTrials.gov (NCT02693535)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
University of Pennsylvania/Abramson Cancer Center — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Carcinoma, Non-Small-Cell Lung Phase 1, Phase 2 Interventional 450 participants sought
Abramson Cancer Center of the University of Pennsylvania ( Site 0010) — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT04165070)

Safety and Tolerability Subretinal OPGx-001 for LCA5-Associated Inherited Retinal Degeneration (LCA5-IRD) and Non-interventional Arm With Untreated Patients

LCA5 Phase 1, Phase 2 Interventional 22 participants sought
University of Pennsylvania Perelman School of Medicine — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Opus Genetics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT05616793)

AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma

Multiple Myeloma Phase 1, Phase 2 Interventional 226 participants sought
Research Site — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06106945)

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes N/A Observational 200 participants sought
The Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Jaeb Center for Health Research
See eligibility & contact on ClinicalTrials.gov (NCT06837181)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures

Osteoporotic Fractures, Osteoporosis N/A Observational 648 participants sought
Thomas Jefferson University Hospital — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: AO Foundation, AO Spine
See eligibility & contact on ClinicalTrials.gov (NCT07027306)

Observational Study of Adults and Adolescents With Erythropoietic Protoporphyria (EPP) and X-linked Porphyria (XLP)

Erythropoietic Protoporphyria (EPP), X-Linked Porphyria (XLP) N/A Observational 50 participants sought
Temple University — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Portal Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07567131)
Actively enrolling

Studies you may be able to join near Philadelphia

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Philadelphia

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

DM Clinical Research-Philadelphia

★ 4.6
231 N Broad St Fl 3, Philadelphia, PA 19107
(267) 376-9392
"Everyone here is polite and professional and I've been here more than once."
— cory scott, 5★

Jefferson Clinical Research Institute

★ 1.7
833 Chestnut St Ste 900, Philadelphia, PA 19107
(215) 955-9987
"The doctors are great but the administration is beyond horrible. Every point of contact has been a disaster and the apologies do little to repair the…"
— Lawrence Short, 1★

Smilow Center for Translational Research

★ 4.7
3400 Civic Center Blvd, Philadelphia, PA 19104
(215) 573-6784
"The Smilow Center for Translational Research is a hub of medical innovation located in Philadelphia. It’s where scientists and doctors work together …"
— Anwar M Hossain, 5★

Clinical Research Philadelphia

★ 4.2
9501 Roosevelt Blvd #208, Philadelphia, PA 19114
"If you ever thought of participating in any type of medical research study, don't' hesitate to check out Clinical Research Philadelphia. They have m…"
— Chris Pez, 5★

Lumina Clinical Research Center

1 Utah Ave, Cherry Hill Township, NJ 08002
(856) 857-9500

CenExel Marlton NJ

★ 3.9
30 Lake Center Dr, Marlton, NJ 08053
(888) 437-4104
"" I tony Gibbs really miss staying at CenExel Marlton NJ and a Room in miss getting paid from a study for 3-monthes and that my 2-homes / I believe i…"
— Antoine Gibbs, 5★

Joseph Stokes, Jr. Research Institute

★ 3.0
3615 Civic Center Blvd, Philadelphia, PA 19104
(215) 590-3800
"Tinnitus... is a coded sound signal... from... people who spoke in the past, detected scientifically, or who spoke now and their voices have been tra…"
— أمجد الأسعد, 5★

Lankenau Institute for Medical Research

★ 5.0
100 E Lancaster Ave, Penn Wynne, PA 19096
(484) 476-8400
"I drive quite a distance to see one of the best orthopedic doctors in the Nation! So yes worth every drop of gas. The staff has always been respectfu…"
— Anthony Myers, 5★

Coriell Institute for Medical Research

★ 4.3
403 Haddon Ave, Camden, NJ 08103
(856) 966-7377

Clinical trials in Philadelphia: what's recruiting

The Philadelphia area currently has 2,171 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Philadelphia, the most active research areas are:

  • Cancer & Oncology14 studies
  • Heart & Vascular2 studies
  • Immune & Skin1 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Philadelphia, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Philadelphia

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Philadelphia participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Philadelphia pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Philadelphia safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Philadelphia, PA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Philadelphia?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Philadelphia typically complete one or two studies per year.

Paid clinical trials near Philadelphia

Other metros within reach

Trenton, NJ2,339 Allentown, PA228 Reading, PA271 Staten Island, NY4,282 Lancaster, PA424 Newark, NJ4,276 Jersey City, NJ4,332 Paterson, NJ4,155

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Philadelphia Chronic Kidney Disease (HealthMatch) in Philadelphia Bladder Issues Due To Spinal Cord Injury in Philadelphia All conditions

More of PA

Pittsburgh1,234 York443 Lancaster424 Harrisburg400 Reading271 Allentown228 Scranton91 Erie88

New paid studies open every week

Get an email when a new clinical trial starts recruiting within 30 miles of your ZIP code. No spam — only real studies from the NIH registry.

By subscribing you agree to receive study alert emails. Unsubscribe anytime in one click.

Get free trial alerts