Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/PA/Philadelphia
Updated November 2026 from ClinicalTrials.gov

Paid Clinical Trials in Philadelphia, PA

Studies commonly pay $75 to $4,500 per completed study

2,167 clinical trials are currently recruiting participants within 30 miles of Philadelphia. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

2,167studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Philadelphia right now

Top 25 of 2,167 recruiting studies, sorted by proximity — each links to its official registry page

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications Phase 3 Interventional 115 participants sought
Hospital of the University of Pennsylvania (Adults only) — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Pierre Fabre Medicament
See eligibility & contact on ClinicalTrials.gov (NCT03394365)

CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT

Acute Leukemia, Acute Myeloid Leukemia N/A Interventional 50 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Children's Hospital of Philadelphia
See eligibility & contact on ClinicalTrials.gov (NCT03810196)

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

High Grade Glioma, Diffuse Intrinsic Pontine Glioma Phase 2 Interventional 120 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Nationwide Children's Hospital
See eligibility & contact on ClinicalTrials.gov (NCT05096481)

Assessment of Geriatric Evaluations Impact on New AML Guidance

AML, Adult N/A Observational 100 participants sought
Abramson Cancer Center at University of Pennsylvania — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Abramson Cancer Center at Penn Medicine
See eligibility & contact on ClinicalTrials.gov (NCT05909501)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure

Chronic Lymphocytic Leukaemia, Moderate to Severe Cardiac Impairment Phase 4 Interventional 60 participants sought
Research Site — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06651970)

A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

Neuroblastoma Recurrent Phase 2 Interventional 54 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: St. Jude Children's Research Hospital
See eligibility & contact on ClinicalTrials.gov (NCT07085338)

A Study of Brenipatide in Participants With Alcohol Use Disorder

Alcohol Use Disorder Phase 3 Interventional 1,100 participants sought
Penn Medicine: University of Pennsylvania Health System — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07219953)

CART123 Cells With or Without Ruxolitinib in Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML) Phase 1 Interventional 30 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Stephan Grupp MD PhD
See eligibility & contact on ClinicalTrials.gov (NCT07464951)

One-Time DNA Study for Vasculitis

Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss), Giant Cell Arteritis N/A Observational 1,000 participants sought
University of Pennsylvania — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: University of Pennsylvania
See eligibility & contact on ClinicalTrials.gov (NCT01241305)

Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell Lymphoma

Folliculotropic Mycosis Fungoides, Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma Phase 1, Phase 2 Interventional 78 participants sought
Thomas Jefferson University Hospital — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: City of Hope Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT03011814)

Adaptive Radiation for Abdominopelvic Metastases

Neoplasm - Soft Tissue Pelvis Malignant Secondary, Malignant Neoplasm of Stomach Phase 1 Interventional 30 participants sought
Fox Chase Cancer Center — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Fox Chase Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT05880667)

A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)

PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM) Phase 1 Interventional 9 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Rocket Pharmaceuticals Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05885412)

Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial

Crohn Disease N/A Interventional 60 participants sought
Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Seattle Children's Hospital
See eligibility & contact on ClinicalTrials.gov (NCT06216899)

Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy

Chronic Graft-versus-host Disease (cGVHD) Phase 2 Interventional 120 participants sought
Fox Chase Cancer Center — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: H. Lee Moffitt Cancer Center and Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT06660355)

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes N/A Observational 200 participants sought
The Children's Hospital of Philadelphia — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Jaeb Center for Health Research
See eligibility & contact on ClinicalTrials.gov (NCT06837181)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

Virtual Mindful After Cancer (MAC) Intervention to Promote Sexual Health for Breast and Gynecologic Cancer Survivors

Gynecologic Cancers, Breast Cancer Phase 1 Interventional 60 participants sought
University of Pennsylvania — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Oregon State University
See eligibility & contact on ClinicalTrials.gov (NCT07055854)

A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

Sepsis, Acute Kidney Injury Phase 2 Interventional 124 participants sought
Research Site — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07215702)

Safety, Pharmacokinetics (PK), and Efficacy of ONC-783 in Advanced Solid Tumors

Advanced Solid Tumor Phase 1 Interventional 20 participants sought
University of Pennsylvania Abramson Cancer Center — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: OncoC4, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07408258)

Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

Barrett's Esophagus, Esophageal Neoplasm N/A Observational 2,000 participants sought
University of Pennsylvania — Philadelphia, Pennsylvania (4.1 mi) · Sponsor: Case Western Reserve University
See eligibility & contact on ClinicalTrials.gov (NCT00288119)
Actively enrolling

Studies you may be able to join near Philadelphia

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Philadelphia

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

DM Clinical Research-Philadelphia

★ 4.6
231 N Broad St Fl 3, Philadelphia, PA 19107
(267) 376-9392
"Everyone here is polite and professional and I've been here more than once."
— cory scott, 5★

Jefferson Clinical Research Institute

★ 1.7
833 Chestnut St Ste 900, Philadelphia, PA 19107
(215) 955-9987
"The doctors are great but the administration is beyond horrible. Every point of contact has been a disaster and the apologies do little to repair the…"
— Lawrence Short, 1★

Smilow Center for Translational Research

★ 4.7
3400 Civic Center Blvd, Philadelphia, PA 19104
(215) 573-6784
"The Smilow Center for Translational Research is a hub of medical innovation located in Philadelphia. It’s where scientists and doctors work together …"
— Anwar M Hossain, 5★

Clinical Research Philadelphia

★ 4.2
9501 Roosevelt Blvd #208, Philadelphia, PA 19114
"If you ever thought of participating in any type of medical research study, don't' hesitate to check out Clinical Research Philadelphia. They have m…"
— Chris Pez, 5★

Lumina Clinical Research Center

1 Utah Ave, Cherry Hill Township, NJ 08002
(856) 857-9500

CenExel Marlton NJ

★ 3.9
30 Lake Center Dr, Marlton, NJ 08053
(888) 437-4104
"" I tony Gibbs really miss staying at CenExel Marlton NJ and a Room in miss getting paid from a study for 3-monthes and that my 2-homes / I believe i…"
— Antoine Gibbs, 5★

Joseph Stokes, Jr. Research Institute

★ 3.0
3615 Civic Center Blvd, Philadelphia, PA 19104
(215) 590-3800
"Tinnitus... is a coded sound signal... from... people who spoke in the past, detected scientifically, or who spoke now and their voices have been tra…"
— أمجد الأسعد, 5★

Lankenau Institute for Medical Research

★ 5.0
100 E Lancaster Ave, Penn Wynne, PA 19096
(484) 476-8400
"I drive quite a distance to see one of the best orthopedic doctors in the Nation! So yes worth every drop of gas. The staff has always been respectfu…"
— Anthony Myers, 5★

Coriell Institute for Medical Research

★ 4.3
403 Haddon Ave, Camden, NJ 08103
(856) 966-7377

Clinical trials in Philadelphia: what's recruiting

The Philadelphia area currently has 2,167 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Philadelphia, the most active research areas are:

  • Cancer & Oncology12 studies
  • Heart & Vascular2 studies
  • Immune & Skin1 studies
  • Diabetes & Metabolism1 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from Philadelphia, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Philadelphia

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Philadelphia participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Philadelphia pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Philadelphia safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Philadelphia, PA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Philadelphia?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Philadelphia typically complete one or two studies per year.

Paid clinical trials near Philadelphia

Other metros within reach

Trenton, NJ2,341 Allentown, PA224 Reading, PA267 Staten Island, NY4,289 Lancaster, PA428 Newark, NJ4,281 Jersey City, NJ4,337 Paterson, NJ4,162

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Philadelphia Chronic Kidney Disease (HealthMatch) in Philadelphia Bladder Issues Due To Spinal Cord Injury in Philadelphia All conditions

More of PA

Pittsburgh1,245 York446 Lancaster428 Harrisburg403 Reading267 Allentown224 Scranton96 Erie92

New paid studies open every week

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