Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/PA/Allentown
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Allentown, PA

Studies commonly pay $75 to $4,500 per completed study

228 clinical trials are currently recruiting participants within 30 miles of Allentown. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

228studies recruiting
7+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Allentown right now

Top 25 of 228 recruiting studies, sorted by proximity — each links to its official registry page

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Lymphoma, Non-Hodgkin, Multiple Myeloma Phase 2 Interventional 4,200 participants sought
Lehigh Valley Hospital - Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: American Society of Clinical Oncology
See eligibility & contact on ClinicalTrials.gov (NCT02693535)

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

Metastatic Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8 Phase 2 Interventional 240 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05327686)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer Phase 3 Interventional 600 participants sought
St. Luke's University Health Network — Bethlehem, Pennsylvania (5.9 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06793215)

A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)

Bipolar Disorder, Bipolar Depression Phase 3 Interventional 400 participants sought
Lehigh Center for Clinical Research — Allentown, Pennsylvania (1.1 mi) · Sponsor: Xenon Pharmaceuticals Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07172516)

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Solid Tumors, Hematologic Malignancies Phase 3 Interventional 3,500 participants sought
St. Luke's University Health Network ( Site 0017) — Bethlehem, Pennsylvania (5.9 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT03486873)

Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

Multiple Myeloma Phase 3 Interventional 1,594 participants sought
Lehigh Valley Health Network — Allentown, Pennsylvania (1.1 mi) · Sponsor: European Myeloma Network B.V.
See eligibility & contact on ClinicalTrials.gov (NCT05243797)

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 626 participants sought
Local Institution - Unk041 — Allentown, Pennsylvania (1.1 mi) · Sponsor: Mirati Therapeutics Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04613596)

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

Melanoma Phase 3 Interventional 560 participants sought
St. Luke's University Health Network — Easton, Pennsylvania (14.8 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06246916)

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

Major Depressive Disorder Phase 2 Interventional 164 participants sought
Lehigh Center for Clinical Research — Allentown, Pennsylvania (1.1 mi) · Sponsor: Syndeio Biosciences, Inc
See eligibility & contact on ClinicalTrials.gov (NCT07115329)

LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

Pulmonary Hypertension Associated With HFpEF Phase 3 Interventional 540 participants sought
Tenax Investigational Site — Allentown, Pennsylvania (1.1 mi) · Sponsor: Tenax Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07288398)

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Arrhythmia, Bradycardia N/A Observational 20,000 participants sought
Research site — Allentown, Pennsylvania (1.1 mi) · Sponsor: Medtronic
See eligibility & contact on ClinicalTrials.gov (NCT00271180)

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 335 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05554406)

Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

Arthritis, Unstable Radial Head N/A Interventional 84 participants sought
Lehigh Valley Health Network — Allentown, Pennsylvania (1.1 mi) · Sponsor: Aptis Medical
See eligibility & contact on ClinicalTrials.gov (NCT05796908)

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Anaplastic Kidney Wilms Tumor, Recurrent Kidney Wilms Tumor Phase 2 Interventional 256 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT04322318)

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

Psychosis Associated With Alzheimer's Disease Phase 3 Interventional 410 participants sought
Local Institution - 1019 — Allentown, Pennsylvania (1.1 mi) · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See eligibility & contact on ClinicalTrials.gov (NCT05511363)

Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease

Endometrial Cancer, Endometrioid Adenocarcinoma N/A Observational 1,715 participants sought
Lehigh Valley Health Network — Allentown, Pennsylvania (1.1 mi) · Sponsor: Memorial Sloan Kettering Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT04291612)

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Phase 1, Phase 2 Interventional 960 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: PedAL BCU, LLC
See eligibility & contact on ClinicalTrials.gov (NCT04726241)

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Breast Carcinoma, Colorectal Carcinoma N/A Observational 2,000 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT06418204)

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 Phase 3 Interventional 3,680 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06058377)

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

Liver Neoplasms, Primary Liver Cancer N/A Observational 5,000 participants sought
Lehigh Valley Hospital — Allentown, Pennsylvania (1.1 mi) · Sponsor: HistoSonics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06486454)
Actively enrolling

Studies you may be able to join near Allentown

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Allentown

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Lehigh Center for Clinical Research

★ 5.0
1245 S Cedar Crest Blvd, Allentown, PA 18103
(610) 820-0342
"Staff was very friendly and explained information to me in great detail"
— Virgilio Baello, 5★

Northeast Clinical Research Center

2014 City Line Rd #103, Bethlehem, PA 18017
(610) 433-4100

Northeast Clinical Trials and Research Institute LLC

★ 4.2 (15 reviews)
3465 Nazareth Rd Suite 102, Easton, PA 18045
(833) 330-0930
"Excellent care and professionalism"
— Violeta Navarrete, 5★

Lehigh Valley Cancer Institute

★ 1.0
Salisbury Township, PA 18103
"I'm so disappointed in my Hemo Doctor didn't communicate with me about my chemo treatments it's been a nightmare dealing with the staff here so unhap…"
— Vanessa Rymer, 1★

Targeted Medical Education

2351 Woodland Dr #101, Allentown, PA 18103
(855) 882-9635

Spokenword Clinical Trials Inc.

3465 Nazareth Rd, Easton, PA 18045
(610) 697-9683

Clinical Research Center-Reading

2760 Century Blvd #3, Reading, PA 19610
(610) 375-2466

Clinical trials in Allentown: what's recruiting

The Allentown area currently has 228 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Allentown, the most active research areas are:

  • Cancer & Oncology17 studies
  • Liver & Kidney4 studies
  • Brain & Mental Health3 studies
  • Heart & Vascular3 studies
  • Lungs & Breathing2 studies

Every listing shows the study phase, the recruiting site and its distance from Allentown, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Allentown

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Allentown participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in Allentown safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Allentown, PA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Allentown?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Allentown.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Allentown typically complete one or two studies per year.

Paid clinical trials near Allentown

Other metros within reach

Reading, PA271 Philadelphia, PA2,171 Trenton, NJ2,339 Scranton, PA91 Lancaster, PA424 Newark, NJ4,276 Staten Island, NY4,282 Paterson, NJ4,155

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Allentown Bladder Issues Due To Spinal Cord Injury in Allentown All conditions

More of PA

Philadelphia2,171 Pittsburgh1,234 York443 Lancaster424 Harrisburg400 Reading271 Scranton91 Erie88

New paid studies open every week

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