Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/PA/Allentown
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Allentown, PA

Studies commonly pay $75 to $4,500 per completed study

234 clinical trials are currently recruiting participants within 30 miles of Allentown. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

234studies recruiting
7+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Allentown right now

Top 25 of 234 recruiting studies, sorted by proximity — each links to its official registry page

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05561387)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

PUSH-IT Continuing Enteral Feeds for Tracheostomy

Tracheostomy Complication, Critical Illness N/A Interventional 200 participants sought
Lehigh Valley Health Network — Allentown, Pennsylvania (1.1 mi) · Sponsor: State University of New York at Buffalo
See eligibility & contact on ClinicalTrials.gov (NCT05906472)

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer Phase 3 Interventional 600 participants sought
St. Luke's University Health Network — Bethlehem, Pennsylvania (5.9 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06793215)

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

Epithelial Ovarian Cancer, Fallopian Tube Cancer Phase 2 Interventional 140 participants sought
St. Lukes University Hospital /ID# 274362 — Bethlehem, Pennsylvania (5.9 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06890338)

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Lymphoma, Non-Hodgkin, Multiple Myeloma Phase 2 Interventional 4,200 participants sought
Lehigh Valley Hospital - Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: American Society of Clinical Oncology
See eligibility & contact on ClinicalTrials.gov (NCT02693535)

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Solid Tumors, Hematologic Malignancies Phase 3 Interventional 3,500 participants sought
St. Luke's University Health Network ( Site 0017) — Bethlehem, Pennsylvania (5.9 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT03486873)

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 189 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT02734537)

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

Hypertension, Hypertension, Systolic N/A Interventional 316 participants sought
Penn Medicine at Doylestown Health Cardiology — Doylestown, Pennsylvania (26.8 mi) · Sponsor: Orchestra BioMed, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06059638)

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

Major Depressive Disorder Phase 2 Interventional 164 participants sought
Lehigh Center for Clinical Research — Allentown, Pennsylvania (1.1 mi) · Sponsor: Syndeio Biosciences, Inc
See eligibility & contact on ClinicalTrials.gov (NCT07115329)

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Arrhythmia, Bradycardia N/A Observational 20,000 participants sought
Research site — Allentown, Pennsylvania (1.1 mi) · Sponsor: Medtronic
See eligibility & contact on ClinicalTrials.gov (NCT00271180)

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Malignancy N/A Observational 240 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04242095)

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Anaplastic Kidney Wilms Tumor, Recurrent Kidney Wilms Tumor Phase 2 Interventional 256 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT04322318)

A Fruit and Vegetable Prescription Program

Diabetes Mellitus, Diabetes Complications N/A Interventional 120 participants sought
Penn State Health St. Joseph Downtown Campus — Reading, Pennsylvania (29.8 mi) · Sponsor: Milton S. Hershey Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT06107816)

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

Colorectal Cancer Stage II, Colorectal Cancer Stage III Phase 3 Interventional 1,057 participants sought
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania (1.1 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT07018869)

Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease

Triple Negative Breast Cancer, Non Small Cell Lung Cancer Phase 2 Interventional 145 participants sought
Lehigh Valley Health Network — Allentown, Pennsylvania (1.1 mi) · Sponsor: Memorial Sloan Kettering Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT03808337)

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

Liver Neoplasms, Primary Liver Cancer N/A Observational 5,000 participants sought
Lehigh Valley Hospital — Allentown, Pennsylvania (1.1 mi) · Sponsor: HistoSonics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06486454)

Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula

Pancreatic Carcinoma, Pancreatic Neoplasm Phase 3 Interventional 274 participants sought
Saint Luke's Cancer Center - Allentown — Allentown, Pennsylvania (1.1 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT06807437)

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Cancer (CRC) Phase 3 Interventional 600 participants sought
Clinical Study Site — Sellersville, Pennsylvania (19.0 mi) · Sponsor: Summit Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT07228832)

Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention

Suicide and Depression, Adolescent Behavior N/A Interventional 900 participants sought
Berks Community Health Center — Reading, Pennsylvania (29.8 mi) · Sponsor: University of Pittsburgh
See eligibility & contact on ClinicalTrials.gov (NCT05748730)

Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease

Diabetic Kidney Disease (DKD) Phase 2 Interventional 270 participants sought
Northeast Clinical Research Center — Bethlehem, Pennsylvania (5.9 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07271186)
Actively enrolling

Studies you may be able to join near Allentown

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Allentown

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Lehigh Center for Clinical Research

★ 5.0
1245 S Cedar Crest Blvd, Allentown, PA 18103
(610) 820-0342
"Staff was very friendly and explained information to me in great detail"
— Virgilio Baello, 5★

Northeast Clinical Research Center

2014 City Line Rd #103, Bethlehem, PA 18017
(610) 433-4100

Northeast Clinical Trials and Research Institute LLC

★ 4.2 (15 reviews)
3465 Nazareth Rd Suite 102, Easton, PA 18045
(833) 330-0930
"Excellent care and professionalism"
— Violeta Navarrete, 5★

Lehigh Valley Cancer Institute

★ 1.0
Salisbury Township, PA 18103
"I'm so disappointed in my Hemo Doctor didn't communicate with me about my chemo treatments it's been a nightmare dealing with the staff here so unhap…"
— Vanessa Rymer, 1★

Targeted Medical Education

2351 Woodland Dr #101, Allentown, PA 18103
(855) 882-9635

Spokenword Clinical Trials Inc.

3465 Nazareth Rd, Easton, PA 18045
(610) 697-9683

Clinical Research Center-Reading

2760 Century Blvd #3, Reading, PA 19610
(610) 375-2466

Clinical trials in Allentown: what's recruiting

The Allentown area currently has 234 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Allentown, the most active research areas are:

  • Cancer & Oncology15 studies
  • Diabetes & Metabolism3 studies
  • Liver & Kidney3 studies
  • Heart & Vascular2 studies
  • Brain & Mental Health2 studies

Every listing shows the study phase, the recruiting site and its distance from Allentown, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Allentown

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Allentown participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in Allentown safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Allentown, PA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Allentown?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Allentown.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Allentown typically complete one or two studies per year.

Paid clinical trials near Allentown

Other metros within reach

Reading, PA280 Philadelphia, PA2,177 Trenton, NJ2,350 Scranton, PA99 Lancaster, PA431 Newark, NJ4,264 Staten Island, NY4,271 Paterson, NJ4,141

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Allentown Bladder Issues Due To Spinal Cord Injury in Allentown All conditions

More of PA

Philadelphia2,177 Pittsburgh1,232 York447 Lancaster431 Harrisburg402 Reading280 Scranton99 Erie89

New paid studies open every week

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