Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/PA/Pittsburgh
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Pittsburgh, PA

Studies commonly pay $75 to $4,500 per completed study

1,232 clinical trials are currently recruiting participants within 30 miles of Pittsburgh. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,232studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Pittsburgh right now

Top 25 of 1,232 recruiting studies, sorted by proximity — each links to its official registry page

Pupil-Indexed Noninvasive Neuromodulation

Paresis N/A Interventional 110 participants sought
VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: VA Office of Research and Development
See eligibility & contact on ClinicalTrials.gov (NCT06282406)

A Non-interventional, International, Multicentre Clinical Research Study to Build the Largest Collection of Multimodal Data (Including Clinical Data, Imaging Data and Omics Data) in Oncology

Diffuse Large B Cell Lymphoma, Solid Tumor Cancer N/A Observational 7,000 participants sought
University of Pittsburgh — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: OWKIN
See eligibility & contact on ClinicalTrials.gov (NCT06625203)

Expiratory Muscle Strength Training for Hypernasal Speech in Children

Velopharyngeal Insufficiency, Velopharyngeal Incompetence Due to Cleft Palate N/A Interventional 30 participants sought
UPMC Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Noel Jabbour
See eligibility & contact on ClinicalTrials.gov (NCT05492266)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Children's Hospital of Pittsburgh of UPMC — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

Thrombocythemia, Essential, Primary Myelofibrosis Phase 3 Interventional 400 participants sought
UPMC Hillman Cancer Center ( Site 6004) — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06351631)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems

Peripheral Neuropathies, Peripheral Neuropathy Due to Chemotherapy N/A Interventional 200 participants sought
University of Pittsburgh — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: RxFunction Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06959277)

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

Urothelial Cancer, Bladder Cancer Phase 2, Phase 3 Interventional 630 participants sought
Research Site — Monroeville, Pennsylvania (10.0 mi) · Sponsor: Daiichi Sankyo
See eligibility & contact on ClinicalTrials.gov (NCT07129993)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
UPMC-Saint Margaret — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Allegheny General Hospital — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

Study of Sodium Phenylbutyrate (ACER-001) for the Treatment of Pediatric and Adults Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)

Medium-chain Acyl-CoA Dehydrogenase Deficiency Phase 2 Interventional 24 participants sought
UPMC Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Jerry Vockley, MD, PhD
See eligibility & contact on ClinicalTrials.gov (NCT06773026)

A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE)

Colo-rectal Cancer Phase 2 Interventional 79 participants sought
Allegheny General Hospital — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: NSABP Foundation Inc
See eligibility & contact on ClinicalTrials.gov (NCT07058012)

ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile Infection

Clostridium Difficile Infection Recurrence Phase 2 Interventional 20 participants sought
Romano, Pontzer & Associated — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Acurx Pharmaceuticals Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07513285)

Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8 Phase 3 Interventional 428 participants sought
Bryn Mawr Hospital — Bryn Mawr, Pennsylvania (11.0 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05646316)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06129864)

A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)

Chronic Graft-versus-host-disease Phase 2 Interventional 60 participants sought
Childrens Hospital of Pittsburgh — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Incyte Corporation
See eligibility & contact on ClinicalTrials.gov (NCT07124078)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
AHN Allegheny General Hospital — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

Safety And Tolerability Of Gamma Glutamylcysteine (GGC) Oral Supplementation In MCI Patients

Mild Cognitive Impairment (MCI) Phase 1 Interventional 9 participants sought
UPMC Presbyterian Hospital — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Pravat Mandal
See eligibility & contact on ClinicalTrials.gov (NCT07583251)
Actively enrolling

Studies you may be able to join near Pittsburgh

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Pittsburgh

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

University of Pittsburgh, Institute for Clinical Research Education (ICRE)

Parkvale Building, 200 Meyran Ave, Pittsburgh, PA 15213

Clinical and Translational Science Institute (CTSI)

★ 5.0
Forbes Tower, Meyran Ave Ste 7057, Pittsburgh, PA 15213
(412) 648-4185
"They helped me when no one else could or would! Thank you CTSI at Pitt, thank you."
— Zachary Ferguson, 5★

University of Pittsburgh Center for Behavioral Health and Smart Technology

Professional Building, 230 McKee Pl #600, Pittsburgh, PA 15213
(412) 692-4758

Physical Therapy-Clinical Research Center

100 Technology Dr, Pittsburgh, PA 15219

Magee-Womens Research Institute

★ 4.4
204 Craft Ave, Pittsburgh, PA 15213
(412) 641-6091
"Wish I could rate zero stars. I had a serious surgery done March 14,2023 and my medical staff neglected to provide me with any discharge meds someone…"
— Lolita 'Lolo' (Lolo), 1★

Alzheimer Disease Research Center

200 Lothrop St, Pittsburgh, PA 15213
(412) 692-2700

UPMC Hillman Cancer Center: Research Pavilion

5115 Centre Ave #2, Pittsburgh, PA 15232

University of Pittsburgh O'Brien Center for Kidney Research

3550 Terrace St, Pittsburgh, PA 15261
(412) 647-3118

University of Pittsburgh Liver Research Center

Biomedical Science Tower, S414, 200 Lothrop St, Pittsburgh, PA 15261
(412) 624-3507

Clinical trials in Pittsburgh: what's recruiting

The Pittsburgh area currently has 1,232 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Pittsburgh, the most active research areas are:

  • Cancer & Oncology11 studies
  • Immune & Skin2 studies
  • Brain & Mental Health1 studies
  • Diabetes & Metabolism1 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from Pittsburgh, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Pittsburgh

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Pittsburgh participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Pittsburgh?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Pittsburgh, PA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Pittsburgh?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Pittsburgh.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Pittsburgh typically complete one or two studies per year.

Paid clinical trials near Pittsburgh

Other metros within reach

Youngstown, OH82 Canton, OH304 Akron, OH394 Erie, PA89 Cleveland, OH1,413 Hagerstown, MD114 Lorain, OH1,309 Buffalo, NY516

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Pittsburgh Bladder Issues Due To Spinal Cord Injury in Pittsburgh All conditions

More of PA

Philadelphia2,177 York447 Lancaster431 Harrisburg402 Reading280 Allentown234 Scranton99 Erie89

New paid studies open every week

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