Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only

Home/PA/Lancaster

Updated October 2026 from ClinicalTrials.gov

Paid Clinical Trials in Lancaster, PA

Studies commonly pay $75 to $4,500 per completed study

426 clinical trials are currently recruiting participants within 30 miles of Lancaster. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

426studies recruiting

1+research centers nearby

4condition categories

Live from the NIH registry

Studies recruiting near Lancaster right now

Top 25 of 426 recruiting studies, sorted by proximity — each links to its official registry page

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought

Ephrata Cancer Center — Ephrata, Pennsylvania (11.5 mi) · Sponsor: SWOG Cancer Research Network

See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer, c-MET Phase 3 Interventional 768 participants sought

Cancer Care Associates Of York /ID# 266143 — York, Pennsylvania (23.2 mi) · Sponsor: AbbVie

See eligibility & contact on ClinicalTrials.gov (NCT04928846)

Observational Study Protocol: LIVER-R

Hepatobiliary Cancers N/A Observational 4,000 participants sought

Research Site — Lancaster, Pennsylvania (0.4 mi) · Sponsor: AstraZeneca

See eligibility & contact on ClinicalTrials.gov (NCT06252753)

Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma

Neuroblastoma Phase 2 Interventional 98 participants sought

Penn State Milton S. Hershey Medical Center and Children's Hospital — Hershey, Pennsylvania (25.0 mi) · Sponsor: Giselle Sholler

See eligibility & contact on ClinicalTrials.gov (NCT06540963)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought

Cancer Care Associates Of York ( Site 0174) — York, Pennsylvania (23.2 mi) · Sponsor: Merck Sharp & Dohme LLC

See eligibility & contact on ClinicalTrials.gov (NCT06890884)

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

Non-Small Cell Lung Cancer (NSCLC) Phase 3 Interventional 750 participants sought

Lancaster General Hospital — Lancaster, Pennsylvania (0.4 mi) · Sponsor: Bristol-Myers Squibb

See eligibility & contact on ClinicalTrials.gov (NCT07361510)

The Pediatric Anesthesia Quality Improvement Project

Surgery, Anesthesia N/A Observational 5,000,000 participants sought

Penn State Hershey Children's Hospital — Hershey, Pennsylvania (25.0 mi) · Sponsor: The Society for Pediatric Anesthesia

See eligibility & contact on ClinicalTrials.gov (NCT00674388)

RA-PRO PRAGMATIC TRIAL

Rheumatoid Arthritis Phase 3 Interventional 924 participants sought

PA Regional Center for Arthritis and Osteoporosis Research — Wyomissing, Pennsylvania (26.6 mi) · Sponsor: University of Alabama at Birmingham

See eligibility & contact on ClinicalTrials.gov (NCT04692493)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought

Research Site — Hershey, Pennsylvania (25.0 mi) · Sponsor: AstraZeneca

See eligibility & contact on ClinicalTrials.gov (NCT06989112)

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis With Cardiomyopathy Phase 3 Interventional 1,750 participants sought

Clinical Trial Site — Lancaster, Pennsylvania (0.4 mi) · Sponsor: Alnylam Pharmaceuticals

See eligibility & contact on ClinicalTrials.gov (NCT07052903)

IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)

Relapsed/Refractory Primary Central Nervous System Lymphoma Phase 3 Interventional 132 participants sought

Penn State Health Milton S Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: Ono Pharmaceutical Co., Ltd.

See eligibility & contact on ClinicalTrials.gov (NCT07104032)

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

Colitis, Ulcerative Phase 3 Interventional 882 participants sought

Penn State Milton S Hershey Medical Ctr — Hershey, Pennsylvania (25.0 mi) · Sponsor: Janssen Research & Development, LLC

See eligibility & contact on ClinicalTrials.gov (NCT07196748)

WellSpan-THRIVE Cancer QOL Study

Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative, Cancer (Solid Tumors) N/A Observational 1,000 participants sought

WellSpan Ephrata Cancer Center — Ephrata, Pennsylvania (11.5 mi) · Sponsor: WellSpan Health

See eligibility & contact on ClinicalTrials.gov (NCT07433660)

Repeat Biliary Point of Care Ultrasound for Detecting Early Acute Cholecystitis

Cholecystitis, Acute, Biliary Diseases N/A Interventional 90 participants sought

WellSpan Health York Hospital — York, Pennsylvania (23.2 mi) · Sponsor: WellSpan Health

See eligibility & contact on ClinicalTrials.gov (NCT07792200)

A Randomized Multicenter Study for Isolated Skin Vasculitis

Primary Cutaneous Vasculitis, Cutaneous Polyarteritis Nodosa Phase 2 Interventional 90 participants sought

Penn State Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: University of Pennsylvania

See eligibility & contact on ClinicalTrials.gov (NCT02939573)

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought

Penn State Milton S Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: ECOG-ACRIN Cancer Research Group

See eligibility & contact on ClinicalTrials.gov (NCT03937635)

Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

NSCLC, Stage I Phase 2 Interventional 244 participants sought

Penn State Cancer Institute — Hershey, Pennsylvania (25.0 mi) · Sponsor: Greg Durm, MD

See eligibility & contact on ClinicalTrials.gov (NCT04317534)

Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study

Heavy Menstrual Bleeding, Bleeding Disorder N/A Observational 300 participants sought

Penn State Health — Hershey, Pennsylvania (25.0 mi) · Sponsor: Oregon Health and Science University

See eligibility & contact on ClinicalTrials.gov (NCT05916469)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought

Research Site — York, Pennsylvania (23.2 mi) · Sponsor: AstraZeneca

See eligibility & contact on ClinicalTrials.gov (NCT06129864)

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

NSCLC (Non-small Cell Lung Cancer), Non-Small Cell Lung Cancer Phase 3 Interventional 590 participants sought

Penn State Milton S. Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: Revolution Medicines, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06881784)

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Low Grade Astrocytoma, Low Grade Glioma Phase 3 Interventional 170 participants sought

Penn State Children's Hospital — Hershey, Pennsylvania (25.0 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT04166409)

Use of an Intrauterine Manipulator and Its Correlation with Positive Peritoneal Cytology in Early Stage Endometrial Cancers

Endometrial Cancer N/A Interventional 350 participants sought

Wellspan Health — York, Pennsylvania (23.2 mi) · Sponsor: WellSpan Health

See eligibility & contact on ClinicalTrials.gov (NCT04570553)

ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Study

Transitional Cell Cancer of Renal Pelvis and Ureter Phase 3 Interventional 100 participants sought

The Pennsylvania State University (Penn State) Milton S. Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: Steba Biotech S.A.

See eligibility & contact on ClinicalTrials.gov (NCT04620239)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,209 participants sought

Ephrata Cancer Center — Ephrata, Pennsylvania (11.5 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT05946213)

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer Phase 3 Interventional 600 participants sought

Reading Hospital - McGlinn Cancer Institute — West Reading, Pennsylvania (27.5 mi) · Sponsor: Hoffmann-La Roche

See eligibility & contact on ClinicalTrials.gov (NCT06793215)

Actively enrolling

Studies you may be able to join near Lancaster

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Google-rated

Top-rated research centers in Lancaster

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Clinical Research Center-Reading

2760 Century Blvd #3, Reading, PA 19610

(610) 375-2466

Clinical trials in Lancaster: what's recruiting

The Lancaster area currently has 426 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Lancaster, the most active research areas are:

Cancer & Oncology17 studies
Liver & Kidney2 studies
Immune & Skin2 studies
Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from Lancaster, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Lancaster

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Lancaster participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Lancaster pay?

Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.

Are clinical trials in Lancaster safe?

Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.

How do I join a study in Lancaster, PA?

Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.

Is compensation for clinical trials taxable?

In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.

Can I be in more than one clinical trial at a time?

Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Lancaster typically complete one or two studies per year.

Paid clinical trials near Lancaster

Other metros within reach

York, PA446 Reading, PA269 Harrisburg, PA403 Baltimore, MD1,657 Allentown, PA230 Philadelphia, PA2,174 Frederick, MD258 Washington, DC2,359

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Lancaster Bladder Issues Due To Spinal Cord Injury in Lancaster All conditions

More of PA

Philadelphia2,174 Pittsburgh1,243 York446 Harrisburg403 Reading269 Allentown230 Scranton92 Erie89

New paid studies open every week

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