Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NY/Rochester
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Rochester, NY

Studies commonly pay $75 to $4,500 per completed study

471 clinical trials are currently recruiting participants within 30 miles of Rochester. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

471studies recruiting
8+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Rochester right now

Top 25 of 471 recruiting studies, sorted by proximity — each links to its official registry page

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
University of Rochester — Rochester, New York (0.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Novel Vaccine (EO2463) as Monotherapy and in Combination, for Treatment of Patients With Indolent Non-Hodgkin Lymphoma

Follicular Lymphoma, Marginal Zone Lymphoma Phase 1, Phase 2 Interventional 80 participants sought
University of Rochester Medical Center (URMC) - Wilmot Cancer Institute (WCI) (James P. Wilmot Cancer Center) — Rochester, New York (0.9 mi) · Sponsor: Enterome
See eligibility & contact on ClinicalTrials.gov (NCT04669171)

A Study of ASP3082 in Adults With Advanced Solid Tumors

Solid Tumor Phase 1 Interventional 681 participants sought
University of Rochester Medical Center James P. Wilmot Cancer Center — Rochester, New York (0.9 mi) · Sponsor: Astellas Pharma Inc
See eligibility & contact on ClinicalTrials.gov (NCT05382559)

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Ulcerative Colitis, Crohn's Disease Phase 3 Interventional 240 participants sought
University of Rochester Medical Center - PPDS — Rochester, New York (0.9 mi) · Sponsor: Takeda
See eligibility & contact on ClinicalTrials.gov (NCT05442567)

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 Phase 3 Interventional 1,875 participants sought
University of Rochester — Rochester, New York (0.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05675410)

A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

Multiple Myeloma Phase 2 Interventional 210 participants sought
University of Rochester Medical Center — Rochester, New York (0.9 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06500884)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
Wilmot Cancer Institute — Rochester, New York (0.9 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma

Glioblastoma, GBM Phase 2 Interventional 103 participants sought
University of Rochester — Rochester, New York (0.9 mi) · Sponsor: Alpheus Medical, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07225621)

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma, Grade 3b Follicular Lymphoma Phase 2 Interventional 396 participants sought
University of Rochester — Rochester, New York (0.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05633615)

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

Hypertension, Hypertension, Systolic N/A Interventional 316 participants sought
University of Rochester - Cardiology CCTU — Rochester, New York (0.9 mi) · Sponsor: Orchestra BioMed, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06059638)

Investigation of Standard Excision Surgical Margins Using Two Photon Fluorescence Microscopy

Basal Cell Carcinoma N/A Interventional 52 participants sought
Rochester Dermatologic Surgery — Victor, New York (16.5 mi) · Sponsor: University of Rochester
See eligibility & contact on ClinicalTrials.gov (NCT06473103)

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Metastatic Castration Sensitive Prostate Cancer (mCSPC), Hormone Sensitive Prostate Cancer Phase 3 Interventional 1,000 participants sought
University of Rochester Medical Center — Rochester, New York (0.9 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07028853)

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

Heart Failure With Preserved Ejection Fraction (HFpEF N/A Interventional 150 participants sought
Rochester General Hospital — Rochester, New York (0.9 mi) · Sponsor: Axon Therapies, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04592445)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
University of Rochester — Rochester, New York (0.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05561387)

A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

Acute HIV Infection Phase 2 Interventional 48 participants sought
31787, University of Rochester Adult HIV Therapeutic Strategies Network CRS — Rochester, New York (0.9 mi) · Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
See eligibility & contact on ClinicalTrials.gov (NCT05719441)

To Assess the Safety and Efficacy of SP-002 with Vismodegib for the Treatment of Locally Advanced Basal Cell Carcinoma

Basal Cell Carcinoma Phase 2 Interventional 80 participants sought
Research Site — Rochester, New York (0.9 mi) · Sponsor: Stamford Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06344052)

A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

Systemic Lupus Erythematosus, Active Refractory Rheumatoid Arthritis Phase 2 Interventional 220 participants sought
University of Rochester Medical Center — Rochester, New York (0.9 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT06570798)

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

Relapsed Refractory Multiple Myeloma Phase 3 Interventional 508 participants sought
Research Site — Rochester, New York (0.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07391657)

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

Aortic Valve Insufficiency, Aortic Valve Stenosis N/A Interventional 200 participants sought
Rochester General Hospital — Rochester, New York (0.9 mi) · Sponsor: Edwards Lifesciences
See eligibility & contact on ClinicalTrials.gov (NCT05172973)

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

Asthma Phase 3 Interventional 440 participants sought
Research Site — Rochester, New York (0.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06307665)

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Diabetes Mellitus, Type 2, Hypertension Phase 3 Interventional 11,800 participants sought
Rochester Clinical Research, Inc — Rochester, New York (0.9 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07064473)
Actively enrolling

Studies you may be able to join near Rochester

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Rochester

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Rochester Clinical Research, LLC

★ 4.7
500 Helendale Rd, Rochester, NY 14609
(585) 288-0890
"All the staff members are professional, efficient and kind.The nurses are easy to connect with. Great experience!"
— Denise Derrick, 5★

Clinical Research Center

500 Helendale Rd, Rochester, NY 14609
(585) 288-0890

Clinical Translational Science Institute

★ 5.0
265 Crittenden Blvd, Rochester, NY 14642
(585) 275-2107
"Super nice people. We're working on the building and their staff has been very professional to work with."
— Eric Bracken, 5★

LDM Clinical Research Source

425 East Ridge Road Box 17221, Rochester, NY 14621
(585) 654-8878

Clinical Research Institute, University

601 Elmwood Ave, Rochester, NY 14642

Clinical Trials

601 Elmwood Ave, Rochester, NY 14642

UR Medicine Saunders Research Building

265 Crittenden Blvd, Rochester, NY 14620
(585) 275-2107

Center For Clinical Research

Rochester, NY 14623
(585) 273-2518

Clinical trials in Rochester: what's recruiting

The Rochester area currently has 471 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Rochester, the most active research areas are:

  • Cancer & Oncology13 studies
  • Immune & Skin3 studies
  • Heart & Vascular3 studies
  • Brain & Mental Health2 studies
  • Lungs & Breathing1 studies

Every listing shows the study phase, the recruiting site and its distance from Rochester, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Rochester

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Rochester participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Rochester pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Rochester?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Rochester?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Rochester?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Rochester.

Paid clinical trials near Rochester

Other metros within reach

Buffalo, NY516 Syracuse, NY249 Binghamton, NY21 Scranton, PA99 Erie, PA89 Harrisburg, PA402 Reading, PA280 York, PA447

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Rochester Bladder Issues Due To Spinal Cord Injury in Rochester All conditions

More of NY

Staten Island4,271 Brooklyn4,269 New York4,206 Manhattan4,198 Bronx4,178 Queens4,161 Yonkers4,153 Buffalo516 Syracuse249 Albany197 Poughkeepsie77

New paid studies open every week

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