Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NY/Rochester
Updated November 2026 from ClinicalTrials.gov

Paid Clinical Trials in Rochester, NY

Studies commonly pay $75 to $4,500 per completed study

473 clinical trials are currently recruiting participants within 30 miles of Rochester. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

473studies recruiting
8+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Rochester right now

Top 25 of 473 recruiting studies, sorted by proximity — each links to its official registry page

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy (SMA) N/A Observational 700 participants sought
University of Rochester Medical Center — Rochester, New York (0.9 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT04174157)

A Novel Vaccine (EO2463) as Monotherapy and in Combination, for Treatment of Patients With Indolent Non-Hodgkin Lymphoma

Follicular Lymphoma, Marginal Zone Lymphoma Phase 1, Phase 2 Interventional 80 participants sought
University of Rochester Medical Center (URMC) - Wilmot Cancer Institute (WCI) (James P. Wilmot Cancer Center) — Rochester, New York (0.9 mi) · Sponsor: Enterome
See eligibility & contact on ClinicalTrials.gov (NCT04669171)

A Study of ASP3082 in Adults With Advanced Solid Tumors

Solid Tumor Phase 1 Interventional 681 participants sought
University of Rochester Medical Center James P. Wilmot Cancer Center — Rochester, New York (0.9 mi) · Sponsor: Astellas Pharma Inc
See eligibility & contact on ClinicalTrials.gov (NCT05382559)

Access to Genetic Testing in Underserved Patients With Cancer

Breast Carcinoma, Male Breast Carcinoma N/A Interventional 800 participants sought
University of Rochester — Rochester, New York (0.9 mi) · Sponsor: University of Southern California
See eligibility & contact on ClinicalTrials.gov (NCT06422455)

RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures

Focal Onset Seizures Phase 2 Interventional 216 participants sought
University of Rochester Medical Center — Rochester, New York (0.9 mi) · Sponsor: Supernus Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06798896)

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

Prostate Cancer Phase 3 Interventional 940 participants sought
University of Rochester Medical Ctr — Rochester, New York (0.9 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06855277)

S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8, Estrogen Receptor Positive N/A Interventional 739 participants sought
University of Rochester — Rochester, New York (0.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03723928)

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 Phase 3 Interventional 1,875 participants sought
University of Rochester — Rochester, New York (0.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05675410)

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

Breast Cancer Phase 3 Interventional 400 participants sought
University of Rochester Cancer Center Pharmacy — Rochester, New York (0.9 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07062965)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
Wilmot Cancer Institute — Rochester, New York (0.9 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

Epileptic Encephalopathy Phase 1, Phase 2 Interventional 20 participants sought
University of Rochester Medical Center — Rochester, New York (0.9 mi) · Sponsor: Institut de Recherches Internationales Servier
See eligibility & contact on ClinicalTrials.gov (NCT07227857)

Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

Rectal Adenocarcinoma, Rectal Cancer Phase 2 Interventional 44 participants sought
University of Rochester Medical Center — Rochester, New York (0.9 mi) · Sponsor: University of Colorado, Denver
See eligibility & contact on ClinicalTrials.gov (NCT07292298)

Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)

Myotonic Dystrophy 1, DM1 N/A Observational 700 participants sought
University of Rochester — Rochester, New York (0.9 mi) · Sponsor: Virginia Commonwealth University
See eligibility & contact on ClinicalTrials.gov (NCT03981575)

Cardiopulmonary Exercise Testing and Oscillometry for the Evaluation of Dyspnea

Breathing, Mouth, Lung Function Decreased N/A Observational 50 participants sought
Highland Hospital — Rochester, New York (0.9 mi) · Sponsor: University of Rochester
See eligibility & contact on ClinicalTrials.gov (NCT06554353)

A Study to Assess Real-world Patient Characteristics and Clinical Course for Symptomatic Patients With PKP2-ACM

Arrhythmogenic Cardiomyopathy, PKP2-ACM N/A Observational 40 participants sought
University of Rochester — Rochester, New York (0.9 mi) · Sponsor: Lexeo Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06976606)

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Metastatic Castration Sensitive Prostate Cancer (mCSPC), Hormone Sensitive Prostate Cancer Phase 3 Interventional 1,000 participants sought
University of Rochester Medical Center — Rochester, New York (0.9 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07028853)

Considering alloHCT: Opportunities for Patient Reflection During Decision-Making Via Digital Stories

Myeloid Malignancy N/A Interventional 120 participants sought
University of Rochester — Rochester, New York (0.9 mi) · Sponsor: University of Rochester
See eligibility & contact on ClinicalTrials.gov (NCT07263074)

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

Metastatic Colorectal Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8 Phase 2 Interventional 146 participants sought
University of Rochester — Rochester, New York (0.9 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05673148)

A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

Acute HIV Infection Phase 2 Interventional 48 participants sought
31787, University of Rochester Adult HIV Therapeutic Strategies Network CRS — Rochester, New York (0.9 mi) · Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
See eligibility & contact on ClinicalTrials.gov (NCT05719441)

A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

Acute Myeloid Leukemia, Myelodysplastic Syndromes Phase 1, Phase 2 Interventional 225 participants sought
The University of Rochester — Rochester, New York (0.9 mi) · Sponsor: Chordia Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05732103)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,500 participants sought
Highland Hospital — Rochester, New York (0.9 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05946213)

A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

Systemic Lupus Erythematosus, Active Refractory Rheumatoid Arthritis Phase 2 Interventional 220 participants sought
University of Rochester Medical Center — Rochester, New York (0.9 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT06570798)
Actively enrolling

Studies you may be able to join near Rochester

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Rochester

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Rochester Clinical Research, LLC

★ 4.7
500 Helendale Rd, Rochester, NY 14609
(585) 288-0890
"All the staff members are professional, efficient and kind.The nurses are easy to connect with. Great experience!"
— Denise Derrick, 5★

Clinical Research Center

500 Helendale Rd, Rochester, NY 14609
(585) 288-0890

Clinical Translational Science Institute

★ 5.0
265 Crittenden Blvd, Rochester, NY 14642
(585) 275-2107
"Super nice people. We're working on the building and their staff has been very professional to work with."
— Eric Bracken, 5★

LDM Clinical Research Source

425 East Ridge Road Box 17221, Rochester, NY 14621
(585) 654-8878

Clinical Research Institute, University

601 Elmwood Ave, Rochester, NY 14642

Clinical Trials

601 Elmwood Ave, Rochester, NY 14642

UR Medicine Saunders Research Building

265 Crittenden Blvd, Rochester, NY 14620
(585) 275-2107

Center For Clinical Research

Rochester, NY 14623
(585) 273-2518

Clinical trials in Rochester: what's recruiting

The Rochester area currently has 473 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Rochester, the most active research areas are:

  • Cancer & Oncology14 studies
  • Brain & Mental Health1 studies
  • Heart & Vascular1 studies
  • Lungs & Breathing1 studies
  • Immune & Skin1 studies

Every listing shows the study phase, the recruiting site and its distance from Rochester, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Rochester

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Rochester participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Rochester pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Rochester?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Rochester?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Rochester?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Rochester.

Paid clinical trials near Rochester

Other metros within reach

Buffalo, NY521 Syracuse, NY256 Binghamton, NY21 Scranton, PA96 Erie, PA92 Harrisburg, PA403 Reading, PA267 York, PA446

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Rochester Bladder Issues Due To Spinal Cord Injury in Rochester All conditions

More of NY

Staten Island4,289 Brooklyn4,288 New York4,217 Manhattan4,215 Bronx4,196 Queens4,178 Yonkers4,171 Buffalo521 Syracuse256 Albany201 Poughkeepsie77

New paid studies open every week

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