Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NE/Lincoln
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Lincoln, NE

Studies commonly pay $75 to $4,500 per completed study

159 clinical trials are currently recruiting participants within 30 miles of Lincoln. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

159studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Lincoln right now

Top 25 of 159 recruiting studies, sorted by proximity — each links to its official registry page

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Saint Elizabeth Regional Medical Center — Lincoln, Nebraska (0.9 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer Phase 3 Interventional 600 participants sought
NHO Revive Research Institute — Lincoln, Nebraska (0.9 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06793215)

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

HER2-positive Breast Cancer, Breast Cancer Phase 2 Interventional 125 participants sought
Cancer Partners of Nebraska — Lincoln, Nebraska (0.9 mi) · Sponsor: Jazz Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07102381)

Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC

Carcinoma, Non-Small-Cell Lung Phase 2 Interventional 120 participants sought
Cancer Partners of Nebraska — Lincoln, Nebraska (0.9 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07489066)

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism Phase 2, Phase 3 Interventional 2,800 participants sought
Bryan Health Pine Lake Campus /ID# 259638 — Lincoln, Nebraska (0.9 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06345339)

BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

Healthy Phase 3 Interventional 6,000 participants sought
Midwest Children's Health Research Center — Lincoln, Nebraska (0.9 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07160244)

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 189 participants sought
Nebraska Hematology and Oncology — Lincoln, Nebraska (0.9 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT02734537)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
Saint Elizabeth Regional Medical Center — Lincoln, Nebraska (0.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05561387)

Randomization of Single vs Multiple Arterial Grafts

Coronary Artery Disease, Heart Diseases N/A Interventional 4,300 participants sought
Nebraska Heart Hospital — Lincoln, Nebraska (0.9 mi) · Sponsor: Weill Medical College of Cornell University
See eligibility & contact on ClinicalTrials.gov (NCT03217006)

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

Clonal Mast Cell Disease, KIT D816V Mutation N/A Observational 750 participants sought
Somnos Clinical Research — Lincoln, Nebraska (0.9 mi) · Sponsor: Blueprint Medicines Corporation
See eligibility & contact on ClinicalTrials.gov (NCT07143669)

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Advanced Non-Small Cell Lung Cancer, Non-Small Cell Lung Cancer Phase 3 Interventional 1,410 participants sought
NHO Revive Research Institute, LLC — Lincoln, Nebraska (0.9 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07222566)

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Malignancy N/A Observational 240 participants sought
Saint Elizabeth Regional Medical Center — Lincoln, Nebraska (0.9 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04242095)

Multi-Site Feasibility Testing of the Ventricular Assist Device Anticipatory Guidance Tool

Ventricular Assist Device, Advanced Heart Failure N/A Observational 10 participants sought
Bryan Heart — Lincoln, Nebraska (0.9 mi) · Sponsor: Bryan Heart
See eligibility & contact on ClinicalTrials.gov (NCT06823583)

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Atherosclerotic Cardiovascular Disease, Overweight Phase 3 Interventional 12,800 participants sought
Bryan Heart — Lincoln, Nebraska (0.9 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037433)

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction Phase 3 Interventional 5,056 participants sought
Bryan Heart — Lincoln, Nebraska (0.9 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037459)

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Cancer (CRC) Phase 3 Interventional 600 participants sought
Clinical Study Site — Lincoln, Nebraska (0.9 mi) · Sponsor: Summit Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT07228832)

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

Heart Failure Phase 3 Interventional 6,000 participants sought
Velocity Clinical Research-Lincoln-69943 — Lincoln, Nebraska (0.9 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT06424288)

Evaluation of Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stones, A Pivotal Trial

Kidney Calculi; Ureteral Calculi N/A Interventional 101 participants sought
Nebraska Urology — Lincoln, Nebraska (0.9 mi) · Sponsor: Avvio Medical
See eligibility & contact on ClinicalTrials.gov (NCT06942949)

Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents

Pneumococcal Disease Phase 3 Interventional 1,200 participants sought
Midwest Children's Health Research Institute — Lincoln, Nebraska (0.9 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07660198)

Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients

Irritability Associated With Autism Spectrum Disorder Phase 3 Interventional 160 participants sought
Alivation Research LLC — Lincoln, Nebraska (0.9 mi) · Sponsor: Intra-Cellular Therapies, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06706674)

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

Non-small Cell Lung Cancer (NSCLC) Phase 3 Interventional 400 participants sought
Research Site — Lincoln, Nebraska (0.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07291037)
Actively enrolling

Studies you may be able to join near Lincoln

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Lincoln

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Celerion

★ 3.5
621 Rose St, Lincoln, NE 68502
(402) 476-2811
"I enjoyed doing a study here, the facility is huge and clean. Most of the staff are warm and friendly some not so much but I just chalked it up to th…"
— viola simms, 5★

Velocity Clinical Research

★ 4.4
4600 Valley Rd, Lincoln, NE 68510
(531) 530-2800
"Nice staff and knowledgeable doctors"
— Lionheart The Great, 5★

UNL Center for Brain, Biology, and Behavior (CB3)

★ 3.0
Stadium East, 1100 T St Suite C89, Lincoln, NE 68588
"Tell others about your experience"
— P Dot, 1★

Be Well Clinical Studies

★ 4.9
5800 Hidcote Dr #103, Lincoln, NE 68516
(402) 937-9392
"Just wonderful people. Very efficient and easy to work with. Excellent experience."
— Prashant Nadkarni, 5★

The NL3 Wang lab

4075 E Campus Loop #101X, Lincoln, NE 68583
(402) 472-0106

UNL Quantitative Life Sciences Initiative

Prem Paul Research Center at Whittier School, 2200 Vine St Ste 230, Lincoln, NE 68503
(402) 472-2512

NHO Revive Research Institute, LLC

4004 Pioneer Woods Dr, Lincoln, NE 68506
(248) 721-9539

UNL Research Compliance Services

Prem S. Paul Research Center at Whittier School, 2200 Vine St Ste 275, Lincoln, NE 68503
(402) 472-6965

Lincoln Medical Education

★ 4.7
4600 Valley Rd, Lincoln, NE 68510
(402) 483-4571
"Great place for the kids to play and learn something too!"
— Bonnie Collins, 5★

Clinical trials in Lincoln: what's recruiting

The Lincoln area currently has 159 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Lincoln, the most active research areas are:

  • Cancer & Oncology9 studies
  • Heart & Vascular5 studies
  • Diabetes & Metabolism2 studies
  • Brain & Mental Health1 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from Lincoln, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Lincoln

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Lincoln participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Lincoln pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Lincoln?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Lincoln safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Lincoln?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Lincoln.

Paid clinical trials near Lincoln

Other metros within reach

Omaha, NE594 Topeka, KS110 Kansas City, KS1,029 Olathe, KS1,025 Kansas City, MO1,018 Sioux Falls, SD265 Overland Park, KS1,017 Des Moines, IA222

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Lincoln Bladder Issues Due To Spinal Cord Injury in Lincoln All conditions

More of NE

Omaha594

New paid studies open every week

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