Do I need to be sick to join a clinical trial in Salinas?

No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.

Are clinical trials in Salinas safe?

Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.

Is compensation for clinical trials taxable?

In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.

How often do new paid studies open in Salinas?

Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Salinas.

Can I be in more than one clinical trial at a time?

Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Salinas typically complete one or two studies per year.

Paid Clinical Trials Salinas, CA — 44 Studies Recruiting (Jul 2026)

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma Phase 3 Interventional 1,450 participants sought

Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (29.6 mi) · Sponsor: ECOG-ACRIN Cancer Research Group

See eligibility & contact on ClinicalTrials.gov (NCT04566328)

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Stage I Breast Cancer Phase 3 Interventional 1,670 participants sought

Dominican Santa Cruz Hospital — Santa Cruz, California (29.6 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT04852887)

A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data

Cancer N/A Observational 20,000 participants sought

Pacific Cancer Care — Monterey, California (15.8 mi) · Sponsor: N-Power Medicine

See eligibility & contact on ClinicalTrials.gov (NCT06877884)

An External Control Arm Study in Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer N/A Observational 650 participants sought

Pacific Cancer Care — Monterey, California (15.8 mi) · Sponsor: N-Power Medicine

See eligibility & contact on ClinicalTrials.gov (NCT07174388)

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Intracranial Meningioma, Recurrent Meningioma Phase 2 Interventional 124 participants sought

Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (29.6 mi) · Sponsor: Alliance for Clinical Trials in Oncology

See eligibility & contact on ClinicalTrials.gov (NCT02523014)

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 Phase 3 Interventional 3,680 participants sought

Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (29.6 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT06058377)

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Lung Non-Small Cell Carcinoma, Lung Non-Small Cell Squamous Carcinoma Phase 3 Interventional 1,210 participants sought

Dominican Santa Cruz Hospital — Santa Cruz, California (29.6 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT04267848)

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Breast Cancer Phase 3 Interventional 4,220 participants sought

Pacific Cancer Care - Oncology — Monterey, California (15.8 mi) · Sponsor: Stemline Therapeutics, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06492616)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought

Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (29.6 mi) · Sponsor: SWOG Cancer Research Network

See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients

Multiple Myeloma Phase 1 Interventional 134 participants sought

Pacific Cancer Care — Monterey, California (15.8 mi) · Sponsor: Oncotherapeutics

See eligibility & contact on ClinicalTrials.gov (NCT03110822)

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma (RCC) Phase 3 Interventional 1,040 participants sought

Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (29.6 mi) · Sponsor: Alliance for Clinical Trials in Oncology

See eligibility & contact on ClinicalTrials.gov (NCT06661720)

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma Phase 3 Interventional 382 participants sought

Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (29.6 mi) · Sponsor: Alliance for Clinical Trials in Oncology

See eligibility & contact on ClinicalTrials.gov (NCT05677490)

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

Coronavirus Disease (COVID-19) Phase 3 Interventional 3,082 participants sought

Clinica de Salud del Valle de Salinas ( Site 3825) — Castroville, California (8.8 mi) · Sponsor: Merck Sharp & Dohme LLC

See eligibility & contact on ClinicalTrials.gov (NCT06667700)

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8 Phase 2 Interventional 66 participants sought

Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (29.6 mi) · Sponsor: SWOG Cancer Research Network

See eligibility & contact on ClinicalTrials.gov (NCT05642572)

Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease

Diabetic Kidney Disease (DKD) Phase 2 Interventional 270 participants sought

Central Coast Nephrology — Salinas, California (1.5 mi) · Sponsor: Regeneron Pharmaceuticals

See eligibility & contact on ClinicalTrials.gov (NCT07271186)

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8 Phase 2 Interventional 56 participants sought

Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (29.6 mi) · Sponsor: SWOG Cancer Research Network

See eligibility & contact on ClinicalTrials.gov (NCT06031688)

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

COPD (Chronic Obstructive Pulmonary Disease) Phase 3 Interventional 5,250 participants sought

Research Site — Castroville, California (8.8 mi) · Sponsor: AstraZeneca

See eligibility & contact on ClinicalTrials.gov (NCT06283966)

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Breast Cancer Phase 3 Interventional 3,960 participants sought

Salinas Valley Memorial — Salinas, California (1.5 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT05879926)

Phase II: Engagement and Clinical Impact of the Teleo Virtual Therapy Platform in Clinical Settings

Anxiety, Mood Disorders N/A Interventional 156 participants sought

Ohana Center for Child and Adolescent Behavioral Health — Monterey, California (15.8 mi) · Sponsor: Stanford University

See eligibility & contact on ClinicalTrials.gov (NCT07155707)

Toddlers' Responses to Strangers

Social Behavior N/A Observational 100 participants sought

Social Science 2 Building — Santa Cruz, California (29.6 mi) · Sponsor: University of California Santa Cruz

See eligibility & contact on ClinicalTrials.gov (NCT06550206)

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

Lumbar Spinal Stenosis N/A Observational 8,000 participants sought

Salinas Surgery Center — Salinas, California (1.5 mi) · Sponsor: Stryker Instruments

See eligibility & contact on ClinicalTrials.gov (NCT03072927)

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Lymphoma, Non-Hodgkin, Multiple Myeloma Phase 2 Interventional 4,200 participants sought

Sutter Palo Alto Medical Foundation: Santa Cruz — Santa Cruz, California (29.6 mi) · Sponsor: American Society of Clinical Oncology

See eligibility & contact on ClinicalTrials.gov (NCT02693535)

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

Pancreatic Acinar Cell Carcinoma, Pancreatic Adenosquamous Carcinoma Phase 2 Interventional 152 participants sought

Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (29.6 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT04858334)

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma Phase 3 Interventional 364 participants sought

Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (29.6 mi) · Sponsor: SWOG Cancer Research Network

See eligibility & contact on ClinicalTrials.gov (NCT04510597)

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

Locally Advanced Pancreatic Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma Phase 3 Interventional 94 participants sought

Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (29.6 mi) · Sponsor: SWOG Cancer Research Network

See eligibility & contact on ClinicalTrials.gov (NCT06998940)

Paid Clinical Trials in Salinas, CA

Studies recruiting near Salinas right now

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data

An External Control Arm Study in Non-Small Cell Lung Cancer

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Phase II: Engagement and Clinical Impact of the Teleo Virtual Therapy Platform in Clinical Settings

Toddlers' Responses to Strangers

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

Top-rated research centers in Salinas

Natividad Medical Center

Clinica de Salud del Valle de Salinas- Sanborn

Lumos Clinical Research Center

San Jose Clinical Trials

UCSF ALS Center at Monterey

ARCpoint Labs of Monterey Bay

Pacific Cancer Care

Naval Postgraduate School

Clinical trials in Salinas: what's recruiting

How to enroll in a paid study in Salinas

Frequently asked questions

Paid clinical trials near Salinas

More of CA

New paid studies open every week