Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CA/San Jose
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in San Jose, CA

Studies commonly pay $75 to $4,500 per completed study

1,134 clinical trials are currently recruiting participants within 30 miles of San Jose. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,134studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near San Jose right now

Top 25 of 1,134 recruiting studies, sorted by proximity — each links to its official registry page

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A

Von Willebrand Disease, Type 3, Concomitant VWD and Hemophilia Phase 1 Interventional 40 participants sought
Stanford University: Stanford Children's Health — Redwood City, California (24.8 mi) · Sponsor: Bleeding and Clotting Disorders Institute Peoria, Illinois
See eligibility & contact on ClinicalTrials.gov (NCT05500807)

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

Drug Resistant Epilepsy, Epilepsy Phase 1, Phase 2 Interventional 8 participants sought
Stanford University School of Medicine — Palo Alto, California (18.9 mi) · Sponsor: NaviFUS Corporation
See eligibility & contact on ClinicalTrials.gov (NCT06388707)

TBI Rehabilitation and Activation in Veterans

Traumatic Brain Injury N/A Interventional 120 participants sought
VA Palo Alto Health Care System — Palo Alto, California (18.9 mi) · Sponsor: Northern California Institute of Research and Education
See eligibility & contact on ClinicalTrials.gov (NCT06562127)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Stanford Women's Cancer Center — Palo Alto, California (18.9 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
Stanford University Medical Center — Stanford, California (19.4 mi) · Sponsor: Medtronic MiniMed, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07228117)

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

Parkinson Disease Phase 2 Interventional 150 participants sought
Parkinson's Research Centers of America (Site #218) — Palo Alto, California (18.9 mi) · Sponsor: Appello Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07432958)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Kaiser Permanente-Santa Teresa-San Jose — San Jose, California (3.7 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Lucile Packard Children's Hospital Stanford University — Palo Alto, California (18.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

Capsule Microbiota Sampling in IBS/Functional Gastrointestinal Disease

IBS - Irritable Bowel Syndrome, Healthy N/A Observational 40 participants sought
Stanford Digestive Health Clinic — Redwood City, California (24.8 mi) · Sponsor: Stanford University
See eligibility & contact on ClinicalTrials.gov (NCT06215222)

Implementing Scalable, PAtient-centered, Team-based, Technology-enabled Care for Adults With Type 2 Diabetes (iPATH)

Diabetes Mellitus, Type 2 N/A Interventional 119,680 participants sought
Board of Trustees of the Leland Stanford Junior University — Stanford, California (19.4 mi) · Sponsor: Stanford University
See eligibility & contact on ClinicalTrials.gov (NCT06251323)

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer Phase 3 Interventional 600 participants sought
Palo Alto Medical Foundation Research Center — Palo Alto, California (18.9 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06793215)

ID Of Prognostic Factors In Mycosis Fungoides/Sezary Syndrome

Mycosis Fungoides, Non-Hodgkin's Lymphoma N/A Observational 2,000 participants sought
Stanford University, School of Medicine — Palo Alto, California (18.9 mi) · Sponsor: Stanford University
See eligibility & contact on ClinicalTrials.gov (NCT02848274)

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

Pulmonary Invasive Fungal Infections, Pulmonary Invasive Aspergillosis N/A Observational 400 participants sought
Lucile Packard Children's Hospital, Stanford University — Palo Alto, California (18.9 mi) · Sponsor: Arkansas Children's Hospital Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT03827694)

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Epic Care-Dublin — Dublin, California (28.1 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

Aortic Valve Insufficiency, Aortic Valve Stenosis N/A Interventional 200 participants sought
Stanford University Medical Center — Stanford, California (19.4 mi) · Sponsor: Edwards Lifesciences
See eligibility & contact on ClinicalTrials.gov (NCT05172973)

Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness

Hearing Loss, Unilateral, Deafness, Unilateral N/A Interventional 60 participants sought
Stanford University — Palo Alto, California (18.9 mi) · Sponsor: Cochlear
See eligibility & contact on ClinicalTrials.gov (NCT05318417)

The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia

Ventilatory Depression, Postoperative Respiratory Failure N/A Interventional 60 participants sought
Stanford University School of Medicine — Stanford, California (19.4 mi) · Sponsor: Stanford University
See eligibility & contact on ClinicalTrials.gov (NCT05379673)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Palo Alto, California (18.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)
Actively enrolling

Studies you may be able to join near San Jose

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in San Jose

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Lumos Clinical Research Center

★ 4.9
2516 Samaritan Dr Ste b, San Jose, CA 95124
(408) 402-5424
"This is my first clinical trial experience and I look forward to many more with Lumos. They have the friendliest staff, they made me feel welcome and…"
— Soso Happy, 5★

San Jose Clinical Trials

★ 4.9
2211 Moorpark Ave #275, San Jose, CA 95128
(408) 443-3540
"Very professional and pleasant atmosphere plus informational"
— Zan Cortner, 5★

Silicon Valley Research Center

★ 5.0
Ringwood Ct, San Jose, CA 95131

IBM Research - Almaden Lab

★ 4.7
650 Harry Rd, San Jose, CA 95120
(408) 927-1080
"This was one of the great research facilities in the world. Unfortunately, it is shut down and in the process of being emptied out. Let's hope for a …"
— Andreas Heinrich, 5★

Dr. Syverain San Jose

★ 5.0
88 Tully Rd, San Jose, CA 95111
(408) 294-9234

Molecular Medicine Research Institute

★ 5.0
428 Oakmead Pkwy, Sunnyvale, CA 94085
(408) 523-6260

Cancer Clinical Trials Office, Stanford Cancer Institute

★ 3.0
800 Welch Rd, Palo Alto, CA 94304
(650) 498-7061
"Do not waitlist here. We've been on waitlist here for over 1.5 yr with nothing to offer. Seek through UCSF or City of Hope."
— Eric Yen, 1★

OIRRC

333 W Maude Ave, Sunnyvale, CA 94085
(669) 699-1080

Vibrant Wellness

★ 4.6
3521 Leonard Ct, Santa Clara, CA 95054
(866) 364-0963

Clinical trials in San Jose: what's recruiting

The San Jose area currently has 1,134 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to San Jose, the most active research areas are:

  • Cancer & Oncology8 studies
  • Diabetes & Metabolism2 studies
  • Brain & Mental Health2 studies
  • Lungs & Breathing2 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from San Jose, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in San Jose

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

San Jose participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in San Jose pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in San Jose safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in San Jose, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in San Jose typically complete one or two studies per year.

Paid clinical trials near San Jose

Other metros within reach

Sunnyvale, CA1,166 Fremont, CA2,256 Santa Cruz, CA164 Hayward, CA2,268 Oakland, CA2,257 Salinas, CA43 Antioch, CA451 Concord, CA1,509

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in San Jose Chronic Kidney Disease (HealthMatch) in San Jose Bladder Issues Due To Spinal Cord Injury in San Jose All conditions

More of CA

Long Beach3,361 Torrance3,253 Fullerton3,246 Anaheim3,181 Garden Grove3,176 Pomona3,138 Glendale2,959 Los Angeles2,949 Huntington Beach2,863 Santa Clarita2,390 Hayward2,268 Oakland2,257

New paid studies open every week

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