Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CA/Santa Cruz
Updated November 2026 from ClinicalTrials.gov

Paid Clinical Trials in Santa Cruz, CA

Studies commonly pay $75 to $4,500 per completed study

174 clinical trials are currently recruiting participants within 30 miles of Santa Cruz. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

174studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Santa Cruz right now

Top 25 of 174 recruiting studies, sorted by proximity — each links to its official registry page

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma Phase 3 Interventional 1,273 participants sought
Kaiser Permanente-Santa Teresa-San Jose — San Jose, California (26.1 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03678025)

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought
Kaiser Permanente-Santa Teresa-San Jose — San Jose, California (26.1 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04251052)

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Cutaneous Melanoma, Stage II N/A Interventional 2,998 participants sought
Stanford Cancer Center South Bay — San Jose, California (26.1 mi) · Sponsor: Melanoma and Skin Cancer Trials Limited
See eligibility & contact on ClinicalTrials.gov (NCT03860883)

A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting

Pneumonia N/A Observational 12,500 participants sought
Kaiser Permanente Santa Clara Medical Center — Santa Clara, California (26.3 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT05452941)

A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

Chronic Idiopathic Constipation (CIC) Phase 3 Interventional 692 participants sought
San Jose Gastroenterology — San Jose, California (26.1 mi) · Sponsor: Ardelyx
See eligibility & contact on ClinicalTrials.gov (NCT07382167)

A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)

Geographic Atrophy Secondary to Age-related Macular Degeneration N/A Observational 75 participants sought
Northern California Retina Vitreous Associates Medical Group — Mountain View, California (28.3 mi) · Sponsor: Complement Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT07144137)

A Study to Evaluate the Maintenance Effect of Osavampator as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder Phase 3 Interventional 550 participants sought
Neurocrine Clinical Site — San Jose, California (26.1 mi) · Sponsor: Neurocrine Biosciences
See eligibility & contact on ClinicalTrials.gov (NCT07196501)

A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

Mature B-Cell Non-Hodgkin Lymphoma Phase 1, Phase 2 Interventional 65 participants sought
Kaiser Permanente - Santa Clara — Santa Clara, California (26.3 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT05533775)

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

Uncontrolled Hypertension Phase 2 Interventional 280 participants sought
Retension Clinical Site — San Jose, California (26.1 mi) · Sponsor: Retension Pharmaceuticals. Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07142356)

A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease

Immunoglobulin G4 Related Disease Phase 3 Interventional 124 participants sought
San Jose Clinical Trials- Site Number : 8400016 — San Jose, California (26.1 mi) · Sponsor: Sanofi
See eligibility & contact on ClinicalTrials.gov (NCT07190196)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (0.4 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis Phase 3 Interventional 2,150 participants sought
Akero Clinical Study Site — San Jose, California (26.1 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06528314)

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

Asthma Phase 3 Interventional 724 participants sought
Teva Investigational Site 12064 — San Jose, California (26.1 mi) · Sponsor: Teva Branded Pharmaceutical Products R&D LLC
See eligibility & contact on ClinicalTrials.gov (NCT06664619)

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma, Stage II Pancreatic Cancer AJCC v8 Phase 3 Interventional 356 participants sought
Palo Alto Medical Foundation-Sunnyvale — Sunnyvale, California (26.9 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06958328)

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Arrhythmia, Bradycardia N/A Observational 20,000 participants sought
Research site — Salinas, California (29.5 mi) · Sponsor: Medtronic
See eligibility & contact on ClinicalTrials.gov (NCT00271180)

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

End Stage Kidney Disease Phase 2, Phase 3 Interventional 3,110 participants sought
Satellite Healthcare — San Jose, California (26.1 mi) · Sponsor: CSL Behring
See eligibility & contact on ClinicalTrials.gov (NCT05485961)

Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)

PTSD, Post Traumatic Stress Disorder PTSD N/A Interventional 40 participants sought
Acacia Research Center — Sunnyvale, California (26.9 mi) · Sponsor: Acacia Clinics
See eligibility & contact on ClinicalTrials.gov (NCT07523685)

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Intracranial Meningioma, Recurrent Meningioma Phase 2 Interventional 124 participants sought
Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (0.4 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT02523014)

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

Hidradenitis Suppurativa (HS) Phase 3 Interventional 600 participants sought
Investigative Site US104 — Sunnyvale, California (26.9 mi) · Sponsor: Incyte Corporation
See eligibility & contact on ClinicalTrials.gov (NCT06855498)

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma, Stage I Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8 Phase 3 Interventional 228 participants sought
Kaiser Permanente-Santa Teresa-San Jose — San Jose, California (26.1 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06992427)

Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration (nAMD) Phase 3 Interventional 480 participants sought
Retinal Diagnostic Center — Campbell, California (21.8 mi) · Sponsor: 4D Molecular Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT07064759)
Actively enrolling

Studies you may be able to join near Santa Cruz

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Santa Cruz

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Institute for the Biology of Stem Cells (IBSC) at UC Santa Cruz

1156 High St, Santa Cruz, CA 95064
(831) 459-1399

Global Psychedelic Dinner

1115 Mission St, Santa Cruz, CA 95060
(831) 429-6362

Lumos Clinical Research Center

★ 4.9
2516 Samaritan Dr Ste b, San Jose, CA 95124
(408) 402-5424
"This is my first clinical trial experience and I look forward to many more with Lumos. They have the friendliest staff, they made me feel welcome and…"
— Soso Happy, 5★

San Jose Clinical Trials

★ 4.9
2211 Moorpark Ave #275, San Jose, CA 95128
(408) 443-3540
"Very professional and pleasant atmosphere plus informational"
— Zan Cortner, 5★

Department of Microbiology and Environmental Toxicology

Santa Cruz, CA 95064
(831) 459-2190

Gonstead Clinical Studies Society

2230 Ivy Ln, Santa Cruz, CA 95062
(831) 476-1873

Cancer Clinical Trials Office, Stanford Cancer Institute

★ 3.0
800 Welch Rd, Palo Alto, CA 94304
(650) 498-7061
"Do not waitlist here. We've been on waitlist here for over 1.5 yr with nothing to offer. Seek through UCSF or City of Hope."
— Eric Yen, 1★

Central Valley Research

★ 4.9
400 E Orangeburg Ave Ste 5, Modesto, CA 95350
(209) 549-9538

Oakland Clinical

3300 Webster St #1106, Oakland, CA 94609
(510) 817-2000

Clinical trials in Santa Cruz: what's recruiting

The Santa Cruz area currently has 174 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Santa Cruz, the most active research areas are:

  • Cancer & Oncology8 studies
  • Heart & Vascular5 studies
  • Brain & Mental Health3 studies
  • Diabetes & Metabolism2 studies
  • Liver & Kidney2 studies

Every listing shows the study phase, the recruiting site and its distance from Santa Cruz, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Santa Cruz

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Santa Cruz participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Santa Cruz pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Santa Cruz safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Santa Cruz, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Santa Cruz?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Santa Cruz typically complete one or two studies per year.

Paid clinical trials near Santa Cruz

Other metros within reach

San Jose, CA1,134 Sunnyvale, CA1,164 Salinas, CA46 Fremont, CA2,265 Hayward, CA2,274 Oakland, CA2,260 San Francisco, CA2,240 Concord, CA1,522

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Santa Cruz Bladder Issues Due To Spinal Cord Injury in Santa Cruz All conditions

More of CA

Long Beach3,380 Fullerton3,269 Torrance3,260 Anaheim3,212 Garden Grove3,202 Pomona3,169 Glendale2,968 Los Angeles2,945 Huntington Beach2,870 Santa Clarita2,368 Hayward2,274 Fremont2,265

New paid studies open every week

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