Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CA/Santa Cruz
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Santa Cruz, CA

Studies commonly pay $75 to $4,500 per completed study

168 clinical trials are currently recruiting participants within 30 miles of Santa Cruz. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

168studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Santa Cruz right now

Top 25 of 168 recruiting studies, sorted by proximity — each links to its official registry page

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (0.4 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Triple-Negative Breast Cancer Phase 3 Interventional 1,530 participants sought
Kaiser Permanente - Santa Clara ( Site 0082) — Santa Clara, California (26.3 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06393374)

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

Uncontrolled Hypertension Phase 2 Interventional 280 participants sought
Retension Clinical Site — San Jose, California (26.1 mi) · Sponsor: Retension Pharmaceuticals. Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07142356)

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Arrhythmia, Bradycardia N/A Observational 20,000 participants sought
Research site — Salinas, California (29.5 mi) · Sponsor: Medtronic
See eligibility & contact on ClinicalTrials.gov (NCT00271180)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
Kaiser Permanente-Santa Teresa-San Jose — San Jose, California (26.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

Locally Advanced Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8 Phase 3 Interventional 474 participants sought
Palo Alto Medical Foundation-Sunnyvale — Sunnyvale, California (26.9 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05624996)

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

Episodic Migraine Phase 3 Interventional 450 participants sought
Lumos Clinical Research Center /ID# 249731 — San Jose, California (26.1 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT05711394)

A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease

Immunoglobulin G4 Related Disease Phase 3 Interventional 124 participants sought
San Jose Clinical Trials- Site Number : 8400016 — San Jose, California (26.1 mi) · Sponsor: Sanofi
See eligibility & contact on ClinicalTrials.gov (NCT07190196)

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube High Grade Serous Adenocarcinoma Phase 3 Interventional 880 participants sought
Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (0.4 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06580314)

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Cancer (CRC) Phase 3 Interventional 600 participants sought
Clinical Study Site — Santa Clara, California (26.3 mi) · Sponsor: Summit Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT07228832)

A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients

Multiple Myeloma Phase 1 Interventional 134 participants sought
Pacific Cancer Care — Monterey, California (27.3 mi) · Sponsor: Oncotherapeutics
See eligibility & contact on ClinicalTrials.gov (NCT03110822)

Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

Non Small Cell Lung Cancer, Epidermal Growth Factor Receptor Gene Mutation N/A Observational 538 participants sought
Stanford Cancer Center South Bay — San Jose, California (26.1 mi) · Sponsor: PrECOG, LLC.
See eligibility & contact on ClinicalTrials.gov (NCT06538038)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,209 participants sought
Kaiser Permanente-Santa Teresa-San Jose — San Jose, California (26.1 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05946213)

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

Locally Advanced Pancreatic Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma Phase 3 Interventional 94 participants sought
Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (0.4 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT06998940)

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Stage III Colon Cancer Phase 2, Phase 3 Interventional 1,912 participants sought
Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California (0.4 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05174169)

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

Lung Non-Small Cell Carcinoma Phase 2 Interventional 88 participants sought
Palo Alto Medical Foundation-Sunnyvale — Sunnyvale, California (26.9 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT06116682)

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung Phase 2 Interventional 480 participants sought
Kaiser Permanente Santa Clara Medical Center — Santa Clara, California (26.3 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06667076)

SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes

Type 1 Diabetes Phase 2 Interventional 159 participants sought
San Jose Clinical Trials, LLC — San Jose, California (26.1 mi) · Sponsor: SAb Biotherapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07187531)

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

Asthma Phase 3 Interventional 724 participants sought
Teva Investigational Site 12064 — San Jose, California (26.1 mi) · Sponsor: Teva Branded Pharmaceutical Products R&D LLC
See eligibility & contact on ClinicalTrials.gov (NCT06664619)

Prevention of Cervical Cancer Using the Genotyping Screening and Same-day Self-sampling

Human Papilloma Virus N/A Observational 5,000 participants sought
Atila Biosystems, Inc. — Sunnyvale, California (26.9 mi) · Sponsor: Atila Biosystems Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07232355)
Actively enrolling

Studies you may be able to join near Santa Cruz

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Santa Cruz

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Institute for the Biology of Stem Cells (IBSC) at UC Santa Cruz

1156 High St, Santa Cruz, CA 95064
(831) 459-1399

Global Psychedelic Dinner

1115 Mission St, Santa Cruz, CA 95060
(831) 429-6362

Lumos Clinical Research Center

★ 4.9
2516 Samaritan Dr Ste b, San Jose, CA 95124
(408) 402-5424
"This is my first clinical trial experience and I look forward to many more with Lumos. They have the friendliest staff, they made me feel welcome and…"
— Soso Happy, 5★

San Jose Clinical Trials

★ 4.9
2211 Moorpark Ave #275, San Jose, CA 95128
(408) 443-3540
"Very professional and pleasant atmosphere plus informational"
— Zan Cortner, 5★

Department of Microbiology and Environmental Toxicology

Santa Cruz, CA 95064
(831) 459-2190

Gonstead Clinical Studies Society

2230 Ivy Ln, Santa Cruz, CA 95062
(831) 476-1873

Cancer Clinical Trials Office, Stanford Cancer Institute

★ 3.0
800 Welch Rd, Palo Alto, CA 94304
(650) 498-7061
"Do not waitlist here. We've been on waitlist here for over 1.5 yr with nothing to offer. Seek through UCSF or City of Hope."
— Eric Yen, 1★

Central Valley Research

★ 4.9
400 E Orangeburg Ave Ste 5, Modesto, CA 95350
(209) 549-9538

Oakland Clinical

3300 Webster St #1106, Oakland, CA 94609
(510) 817-2000

Clinical trials in Santa Cruz: what's recruiting

The Santa Cruz area currently has 168 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Santa Cruz, the most active research areas are:

  • Cancer & Oncology15 studies
  • Heart & Vascular2 studies
  • Diabetes & Metabolism1 studies
  • Lungs & Breathing1 studies

Every listing shows the study phase, the recruiting site and its distance from Santa Cruz, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Santa Cruz

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Santa Cruz participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Santa Cruz pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Santa Cruz safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Santa Cruz, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Santa Cruz?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Santa Cruz typically complete one or two studies per year.

Paid clinical trials near Santa Cruz

Other metros within reach

San Jose, CA1,132 Sunnyvale, CA1,165 Salinas, CA44 Fremont, CA2,254 Hayward, CA2,266 Oakland, CA2,257 San Francisco, CA2,236 Concord, CA1,513

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Santa Cruz Bladder Issues Due To Spinal Cord Injury in Santa Cruz All conditions

More of CA

Long Beach3,348 Torrance3,239 Fullerton3,230 Anaheim3,164 Garden Grove3,162 Pomona3,123 Glendale2,948 Los Angeles2,936 Huntington Beach2,847 Santa Clarita2,389 Hayward2,266 Oakland2,257

New paid studies open every week

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