Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/FL/Leesburg
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Leesburg, FL

Studies commonly pay $75 to $4,500 per completed study

143 clinical trials are currently recruiting participants within 30 miles of Leesburg. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

143studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Leesburg right now

Top 25 of 143 recruiting studies, sorted by proximity — each links to its official registry page

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought
Florida Retina Institute Wildwood — Wildwood, Florida (11.1 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07553429)

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin

Type 2 Diabetes Mellitus, Type 2 Diabetes With Chronic Kidney Disease Phase 3 Interventional 900 participants sought
Research Site — Leesburg, Florida (3.2 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07662135)

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism Phase 2, Phase 3 Interventional 2,800 participants sought
Adult Medicine of Lake County - Mount Dora /ID# 257371 — Mt. Dora, Florida (15.4 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06345339)

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis Phase 3 Interventional 2,150 participants sought
Akero Clinical Study Site — Lady Lake, Florida (10.5 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06528314)

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

Non-Small Cell Lung Cancer (NSCLC) Phase 3 Interventional 750 participants sought
Clermont Oncology Center — Clermont, Florida (16.8 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT07361510)

FX Shoulder Solutions Retrospective / Prospective Clinical Study

Rotator Cuff Syndrome of Shoulder and Allied Disorders, Osteoarthritis Shoulder N/A Observational 600 participants sought
Advanced Orthopedics Institute — The Villages, Florida (12.2 mi) · Sponsor: FX Shoulder Solutions
See eligibility & contact on ClinicalTrials.gov (NCT06077942)

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

Melanoma Phase 3 Interventional 560 participants sought
Clermont Oncology Center — Clermont, Florida (16.8 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06246916)

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Atherosclerotic Cardiovascular Disease, Overweight Phase 3 Interventional 12,800 participants sought
West Orange Endocrinology — Ocoee, Florida (25.4 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037433)

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

Metabolic Dysfunction-Associated Steatotic Liver Disease Phase 3 Interventional 4,500 participants sought
K2 MEDICAL Research THE VILLAGES — Lady Lake, Florida (10.5 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07165028)

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

Psychosis Associated With Alzheimer's Disease Phase 3 Interventional 410 participants sought
Local Institution - 1040 — The Villages, Florida (12.2 mi) · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See eligibility & contact on ClinicalTrials.gov (NCT05511363)

Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design

Fibromyalgia Phase 3 Interventional 620 participants sought
Clinical Research Site — The Villages, Florida (12.2 mi) · Sponsor: Axsome Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07398417)

A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia

Hypercholesterolemia Phase 2 Interventional 420 participants sought
K2 Medical Research The Villages — The Villages, Florida (12.2 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07477704)

A Study to Identify and Characterize Patients With Type 2 Diabetes Mellitus for Possible Participation in Ongoing or Future Type 2 Diabetes Mellitus Clinical Studies

Type 2 Diabetes N/A Observational 2,150 participants sought
Research Site — Leesburg, Florida (3.2 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07606066)

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Locally Advanced Cervical Adenocarcinoma, Locally Advanced Cervical Adenosquamous Carcinoma Phase 3 Interventional 336 participants sought
Health Central — Ocoee, Florida (25.4 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07061977)

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Phase 3 Interventional 1,200 participants sought
Clermont Oncology Center ( Site 0046) — Clermont, Florida (16.8 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06136559)

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

Alzheimer's Disease Phase 3 Interventional 586 participants sought
Charter Research - Lady Lake — The Villages, Florida (12.2 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT06976216)

ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors

Non Small Cell Lung Cancer Phase 3 Interventional 630 participants sought
Florida Cancer Specialists -North - 1125 — The Villages, Florida (12.2 mi) · Sponsor: OncoC4, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05671510)

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

Acne Phase 1, Phase 2 Interventional 800 participants sought
K2 Medical Research - The Villages - Northeast 138th Lane- Site Number : 8400063 — Lady Lake, Florida (10.5 mi) · Sponsor: Sanofi Pasteur, a Sanofi Company
See eligibility & contact on ClinicalTrials.gov (NCT06316297)

Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

Resectable Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8 Phase 3 Interventional 1,100 participants sought
Health Central — Ocoee, Florida (25.4 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06632327)

A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

Alzheimers Disease Phase 3 Interventional 800 participants sought
K2 Medical Research-Winter Garden — Clermont, Florida (16.8 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT07170150)

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia

Healthy Participants, Dyslipidemia Phase 1 Interventional 136 participants sought
Research Site — Inverness, Florida (26.7 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06980428)

A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus Phase 3 Interventional 1,200 participants sought
Research Site — Leesburg, Florida (3.2 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07662213)

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

High Risk Cardiovascular Disease, Hypertension Phase 3 Interventional 11,000 participants sought
Clinical Trial Site — Leesburg, Florida (3.2 mi) · Sponsor: Alnylam Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07181109)

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

Amyloid Plaque, Beta-Amyloid Phase 1, Phase 2 Interventional 304 participants sought
K2 Medical Research The Villages LLC — Lady Lake, Florida (10.5 mi) · Sponsor: AC Immune SA
See eligibility & contact on ClinicalTrials.gov (NCT05462106)

A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)

Multiple Myeloma, Newly Diagnosed Multiple Myeloma Phase 3 Interventional 520 participants sought
GSK Investigational Site — Lady Lake, Florida (10.5 mi) · Sponsor: GlaxoSmithKline
See eligibility & contact on ClinicalTrials.gov (NCT06679101)
Actively enrolling

Studies you may be able to join near Leesburg

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Leesburg

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Flourish Research - Leesburg

★ 5.0
1038 W N Blvd Ste 101, Leesburg, FL 34748
(352) 354-4466

Lakeview Institute of Clinical Research LLC

★ 4.0
410 Fern Dr Research, Leesburg, FL 34748
(352) 782-0606

Synexus Clinical Research Center

★ 3.7
3201 Wedgewood Ln #7179, The Villages, FL 32162
(352) 261-0901
"I had a very positive experience with Synexus Clinical Research in The Villages. The staff was professional, kind, and very helpful throughout the en…"
— Joe Martin, 5★

Orlando Clinical Research Center

★ 4.6
5055 S Orange Ave, Orlando, FL 32809
(407) 240-7878
"Friendly informative doctors and nurses..."
— Jeffrey Kallas, 5★

Charter Research

★ 4.9
1025 Lake Sumter Landing, The Villages, FL 32162
(352) 441-2000
"With appointment, no waiting. Thorough testing for your info only, and for research qualifications. No diagnosis given. Parking nearby"
— Betty Scanlon, 5★

UF Health — Precision Health Research Center

★ 4.5
1400 U.S. 27/441 Suite 820, The Villages, FL 32159
(352) 247-2493
"The dining room and food service at UF Villages is exceptional. Every visit has been a culinary delight. I love the choices available at the various…"
— Nora Cloud, 5★

Florida Cancer Specialists & Research Institute

★ 4.8 (290 reviews)
601 E Dixie Ave Ste 1001, Leesburg, FL 34748
(352) 787-9448
"I highly recommend Dr.Teklie. However, at least for this location in Leesburg, I do not recommend. Trying to get imaging approved through insurance i…"
— Brittany Nadwodny, 1★

Clinical Research AMLC

3587 Lake Center Dr, Mt Dora, FL 32757
(352) 374-0022

K2 Medical Research - The Villages, FL

★ 4.6
1400 US-441 Ste 537, The Villages, FL 32159
(352) 500-5252
"5-Stars! Professional, caring, serious about their work but they maintain a casual, friendly atmosphere. A fine medical facility and staff."
— Eric Ruff, 5★

Clinical trials in Leesburg: what's recruiting

The Leesburg area currently has 143 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Leesburg, the most active research areas are:

  • Cancer & Oncology8 studies
  • Diabetes & Metabolism7 studies
  • Brain & Mental Health4 studies
  • Liver & Kidney3 studies
  • Heart & Vascular2 studies

Every listing shows the study phase, the recruiting site and its distance from Leesburg, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Leesburg

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Leesburg participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Leesburg pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Leesburg?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Leesburg safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How often do new paid studies open in Leesburg?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Leesburg.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Leesburg typically complete one or two studies per year.

Paid clinical trials near Leesburg

Other metros within reach

Ocala, FL135 Orlando, FL942 Kissimmee, FL927 Spring Hill, FL110 Deltona, FL953 Lakeland, FL191 Winter Haven, FL159 Tampa, FL1,335

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Leesburg Bladder Issues Due To Spinal Cord Injury in Leesburg All conditions

More of FL

Fort Lauderdale1,987 Pembroke Pines1,980 Hollywood1,980 Hialeah1,934 Miami1,911 St. Petersburg1,353 Tampa1,335 Deltona953 Orlando942 Kissimmee927 Jacksonville916 Gainesville538

New paid studies open every week

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