Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/FL/Leesburg
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Leesburg, FL

Studies commonly pay $75 to $4,500 per completed study

136 clinical trials are currently recruiting participants within 30 miles of Leesburg. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

136studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Leesburg right now

Top 25 of 136 recruiting studies, sorted by proximity — each links to its official registry page

A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis

Colitis Ulcerative Phase 2 Interventional 204 participants sought
Novum Research- Site Number : 8400018 — Clermont, Florida (16.8 mi) · Sponsor: Sanofi
See eligibility & contact on ClinicalTrials.gov (NCT06867094)

Phase 2 Study of ADX-038 in Participants With Geographic Atrophy

Geographic Atrophy Secondary to Age-related Macular Degeneration Phase 2 Interventional 240 participants sought
ADARx Clinical Site — Wildwood, Florida (11.1 mi) · Sponsor: ADARx Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06990269)

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

Macular Degeneration, Age-Related Macular Degeneration Phase 2, Phase 3 Interventional 960 participants sought
Wildwood Clinical Research / Florida Retina Institute — Wildwood, Florida (11.1 mi) · Sponsor: EyeBiotech Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT07440225)

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Phase 3 Interventional 1,200 participants sought
Clermont Oncology Center ( Site 0046) — Clermont, Florida (16.8 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06136559)

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis, Ulcerative Colitis Chronic Phase 2 Interventional 143 participants sought
Novum Research, LLC — Clermont, Florida (16.8 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT06598943)

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction Phase 3 Interventional 5,056 participants sought
Nature Coast Clinical Research — Inverness, Florida (26.7 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037459)

Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design

Fibromyalgia Phase 3 Interventional 620 participants sought
Clinical Research Site — The Villages, Florida (12.2 mi) · Sponsor: Axsome Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07398417)

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Atherosclerotic Cardiovascular Disease, Overweight Phase 3 Interventional 12,800 participants sought
West Orange Endocrinology — Ocoee, Florida (25.4 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037433)

Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

Chronic Pain, Intractable Pain N/A Interventional 70 participants sought
Orlando Health Neuroscience Institute — Clermont, Florida (16.8 mi) · Sponsor: Boston Scientific Corporation
See eligibility & contact on ClinicalTrials.gov (NCT07190807)

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

Alzheimer Disease, Dementia Phase 3 Interventional 550 participants sought
Charter Research - The Villages — The Villages, Florida (12.2 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07602582)

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

High-Risk Non-Muscle-Invasive Bladder Cancer Phase 2 Interventional 325 participants sought
Advanced Urology Institute — Oxford, Florida (14.0 mi) · Sponsor: CG Oncology, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06567743)

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube High Grade Serous Adenocarcinoma Phase 3 Interventional 880 participants sought
Health Central — Ocoee, Florida (25.4 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06580314)

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

Alzheimer's Disease Phase 3 Interventional 586 participants sought
Charter Research - Lady Lake — The Villages, Florida (12.2 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT06976216)

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

Osteoarthritis, Knee, Diabetic Neuropathic Pain Phase 2 Interventional 10,000 participants sought
K2 MEDICAL Research THE VILLAGES — Lady Lake, Florida (10.5 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT05986292)

ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors

Non Small Cell Lung Cancer Phase 3 Interventional 630 participants sought
Florida Cancer Specialists -North - 1125 — The Villages, Florida (12.2 mi) · Sponsor: OncoC4, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05671510)

Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

Resectable Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8 Phase 3 Interventional 1,100 participants sought
Health Central — Ocoee, Florida (25.4 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06632327)

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

Early Alzheimer's Disease Phase 2 Interventional 340 participants sought
Charter Research - Lady Lake ( Site 1019) — The Villages, Florida (12.2 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT07033494)

A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease

Parkinson Disease Phase 1 Interventional 127 participants sought
K2 Medical Research, LLC — The Villages, Florida (12.2 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT06809400)

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

Obesity or Overweight Phase 3 Interventional 300 participants sought
Charter Research - The Villages — The Villages, Florida (12.2 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07575399)

KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)

Malignant Neoplasm Phase 2 Interventional 140 participants sought
Clermont Oncology Center ( Site 0041) — Clermont, Florida (16.8 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT07252739)

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Non-Small Cell Lung Cancer Phase 3 Interventional 675 participants sought
Research Site — Clermont, Florida (16.8 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06357533)

BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women

Depressive Symptoms, Urinary Incontinence N/A Interventional 60 participants sought
Luxury Psychiatry Clinic — Winter Garden, Florida (23.4 mi) · Sponsor: BTL Industries Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT07413705)
Actively enrolling

Studies you may be able to join near Leesburg

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Leesburg

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Flourish Research - Leesburg

★ 5.0
1038 W N Blvd Ste 101, Leesburg, FL 34748
(352) 354-4466

Lakeview Institute of Clinical Research LLC

★ 4.0
410 Fern Dr Research, Leesburg, FL 34748
(352) 782-0606

Synexus Clinical Research Center

★ 3.7
3201 Wedgewood Ln #7179, The Villages, FL 32162
(352) 261-0901
"I had a very positive experience with Synexus Clinical Research in The Villages. The staff was professional, kind, and very helpful throughout the en…"
— Joe Martin, 5★

Orlando Clinical Research Center

★ 4.6
5055 S Orange Ave, Orlando, FL 32809
(407) 240-7878
"Friendly informative doctors and nurses..."
— Jeffrey Kallas, 5★

Charter Research

★ 4.9
1025 Lake Sumter Landing, The Villages, FL 32162
(352) 441-2000
"With appointment, no waiting. Thorough testing for your info only, and for research qualifications. No diagnosis given. Parking nearby"
— Betty Scanlon, 5★

UF Health — Precision Health Research Center

★ 4.5
1400 U.S. 27/441 Suite 820, The Villages, FL 32159
(352) 247-2493
"The dining room and food service at UF Villages is exceptional. Every visit has been a culinary delight. I love the choices available at the various…"
— Nora Cloud, 5★

Florida Cancer Specialists & Research Institute

★ 4.8 (290 reviews)
601 E Dixie Ave Ste 1001, Leesburg, FL 34748
(352) 787-9448
"I highly recommend Dr.Teklie. However, at least for this location in Leesburg, I do not recommend. Trying to get imaging approved through insurance i…"
— Brittany Nadwodny, 1★

Clinical Research AMLC

3587 Lake Center Dr, Mt Dora, FL 32757
(352) 374-0022

K2 Medical Research - The Villages, FL

★ 4.6
1400 US-441 Ste 537, The Villages, FL 32159
(352) 500-5252
"5-Stars! Professional, caring, serious about their work but they maintain a casual, friendly atmosphere. A fine medical facility and staff."
— Eric Ruff, 5★

Clinical trials in Leesburg: what's recruiting

The Leesburg area currently has 136 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Leesburg, the most active research areas are:

  • Cancer & Oncology8 studies
  • Brain & Mental Health6 studies
  • Diabetes & Metabolism4 studies
  • Immune & Skin3 studies
  • Heart & Vascular3 studies

Every listing shows the study phase, the recruiting site and its distance from Leesburg, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Leesburg

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Leesburg participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Leesburg pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Leesburg?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Leesburg safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How often do new paid studies open in Leesburg?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Leesburg.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Leesburg typically complete one or two studies per year.

Paid clinical trials near Leesburg

Other metros within reach

Ocala, FL124 Orlando, FL928 Kissimmee, FL914 Spring Hill, FL115 Deltona, FL942 Lakeland, FL186 Winter Haven, FL156 Tampa, FL1,316

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Leesburg Bladder Issues Due To Spinal Cord Injury in Leesburg All conditions

More of FL

Fort Lauderdale1,994 Pembroke Pines1,989 Hollywood1,989 Hialeah1,939 Miami1,913 St. Petersburg1,334 Tampa1,316 Deltona942 Orlando928 Kissimmee914 Jacksonville903 Gainesville543

New paid studies open every week

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