Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/FL/Spring Hill
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Spring Hill, FL

Studies commonly pay $75 to $4,500 per completed study

115 clinical trials are currently recruiting participants within 30 miles of Spring Hill. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

115studies recruiting
9+research centers nearby
7condition categories
Live from the NIH registry

Studies recruiting near Spring Hill right now

Top 25 of 115 recruiting studies, sorted by proximity — each links to its official registry page

Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS

COPD, Smoking N/A Interventional 290 participants sought
Advanced Research Institute, Inc — New Port Richey, Florida (19.9 mi) · Sponsor: Philip Morris Products S.A.
See eligibility & contact on ClinicalTrials.gov (NCT07108166)

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction Phase 3 Interventional 5,056 participants sought
Nature Coast Clinical Research — Inverness, Florida (27.4 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037459)

A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

Non-muscle Invasive Bladder Cancer Phase 1 Interventional 294 participants sought
Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida (20.6 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07206225)

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

Episodic Migraine Phase 3 Interventional 450 participants sought
Asclepes Research Centers - Spring Hill /ID# 248525 — Spring Hill, Florida (0.3 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT05711394)

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

Geographic Atrophy, Macular Degeneration N/A Observational 500 participants sought
Retina Specialists of Tampa — Wesley Chapel, Florida (20.6 mi) · Sponsor: Astellas Pharma Global Development, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06779773)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,209 participants sought
Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida (20.6 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05946213)

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

Alzheimer Disease, Dementia Phase 3 Interventional 550 participants sought
Suncoast Clinical Research, Inc. — New Port Richey, Florida (19.9 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07602582)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida (20.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

Multiple conditions Phase 2 Interventional 98 participants sought
Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida (20.6 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06532279)

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

Osteoarthritis, Knee, Diabetic Neuropathic Pain Phase 2 Interventional 10,000 participants sought
Suncoast Clinical Research, Inc. — New Port Richey, Florida (19.9 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT05986292)

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

Hypertension, Hypertension, Systolic N/A Interventional 500 participants sought
Citrus Cardiology Consultants — Crystal River, Florida (29.5 mi) · Sponsor: Orchestra BioMed, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06059638)

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Stage III Colon Cancer Phase 2, Phase 3 Interventional 1,912 participants sought
Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida (20.6 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05174169)

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

Early Alzheimer's Disease Phase 2 Interventional 340 participants sought
Suncoast Clinical Research ( Site 1007) — New Port Richey, Florida (19.9 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT07033494)

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

Cardiovascular, Metabolic Disease Phase 1 Interventional 90 participants sought
Research Site 19 — High Point, Florida (4.6 mi) · Sponsor: CRISPR Therapeutics AG
See eligibility & contact on ClinicalTrials.gov (NCT07491172)

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

Locally Advanced Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma Phase 1, Phase 2 Interventional 37 participants sought
Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida (20.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07012031)

eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation

Pulmonary Disease, Chronic Obstructive Phase 3 Interventional 1,196 participants sought
GSK Investigational Site — Crystal River, Florida (29.5 mi) · Sponsor: GlaxoSmithKline
See eligibility & contact on ClinicalTrials.gov (NCT07177339)

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

Colitis, Ulcerative Phase 3 Interventional 882 participants sought
Nature Coast Clinical Research — Inverness, Florida (27.4 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07196748)

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism Phase 2, Phase 3 Interventional 2,800 participants sought
Suncoast Clinical Research Pasco County /ID# 257018 — New Port Richey, Florida (19.9 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06345339)

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Obesity, Heart Failure Phase 3 Interventional 5,610 participants sought
Suncoast Clinical Research, Inc. — New Port Richey, Florida (19.9 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07567001)

A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

Arthritis, Psoriatic Phase 3 Interventional 750 participants sought
Suncoast Clinical Research — New Port Richey, Florida (19.9 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06807424)

A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

Psoriatic Arthritis, Axial Spondyloarthritis Phase 1 Interventional 392 participants sought
Pa0019 133 — Zephyrhills, Florida (27.2 mi) · Sponsor: UCB Biopharma SRL
See eligibility & contact on ClinicalTrials.gov (NCT07290036)

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

Overweight, Obesity Phase 2 Interventional 400 participants sought
Suncoast Clinical Research, Inc. — New Port Richey, Florida (19.9 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07589608)
Actively enrolling

Studies you may be able to join near Spring Hill

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Spring Hill

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Access Research Institute

★ 4.7
11373 Cortez Blvd Bldg C, Suite 200, Brooksville, FL 34613
(352) 691-1140
"Monika, Marilyn and shirin make my visits Easy enjoyable there was a point when I was about to quit and Monika and Marilyn spoke to me with kindness …"
— Peter Battista, 5★

Florida Cancer Specialists & Research Institute

★ 4.8 (393 reviews)
11063 County Line Rd, Spring Hill, FL 34609
(352) 688-7744
"PATRICIA lab technician she’s always smiling and hiding how rude she is she’s not professional"
— GENEISY CARTAYA VASALLO, 1★

Advanced Research Institute, Inc.

★ 5.0
7114 Congress St, New Port Richey, FL 34653
(727) 835-3261
"⭐️⭐️⭐️⭐️⭐️I was part of a clinical trial with ARI Clinical Research Florida for a little over two years, going in monthly — and I can honestly s…"
— Kimberly Hayward-Knapp, 5★

Clinical Research of West Florida, Inc - Tampa

★ 4.7
605 N Howard Ave, Tampa, FL 33606
(813) 870-1292
"Clinical research of West Florida is a great place the staff is friendly the nurses they all are great the doctor is very good I enjoyed being there …"
— Kelly Musgrave, 5★

Florida Cancer Specialists & Research Institute

★ 4.9 (723 reviews)
7154 Medical Center Dr, Spring Hill, FL 34608
(352) 596-1926

CenExel Tampa FL

★ 4.1
15416 N Florida Ave, Tampa, FL 33613
(813) 264-2155
"I am extremely disappointed with my experience and feel that I am being unfairly penalized for a mistake that was not my fault.<br><br>I participated…"
— D Hiddle, 1★

Suncoast Clinical Research

★ 5.0
5604 Gulf Dr, New Port Richey, FL 34652
(727) 849-4131
"Everyone was so friendly and professional. I felt well cared for and appreciated being part of something that helps advance medical research."
— Jana Waterworth, 5★

Florida Cancer Specialists & Research Institute

★ 4.6 (110 reviews)
14529 Cortez Blvd, Brooksville, FL 34613
(352) 596-1401
"I love Dr Malhotra,Dr Tang,Dr Li,"
— Michele Ricci, 5★

Clinical Research of West Florida , Inc - Clearwater

★ 4.9
2147 NE Coachman Rd, Clearwater, FL 33765
(727) 466-0078
"I have done several studies with this company and they are simply amazing. Every single person that works there genuinely cares about you. They are p…"
— Barbara Burns, 5★

Clinical trials in Spring Hill: what's recruiting

The Spring Hill area currently has 115 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Spring Hill, the most active research areas are:

  • Cancer & Oncology6 studies
  • Diabetes & Metabolism5 studies
  • Immune & Skin5 studies
  • Heart & Vascular4 studies
  • Lungs & Breathing3 studies

Every listing shows the study phase, the recruiting site and its distance from Spring Hill, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Spring Hill

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Spring Hill participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Spring Hill?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Spring Hill, FL?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Spring Hill?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Spring Hill?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Spring Hill.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Spring Hill typically complete one or two studies per year.

Paid clinical trials near Spring Hill

Other metros within reach

Tampa, FL1,316 Leesburg, FL136 St. Petersburg, FL1,334 Lakeland, FL186 Ocala, FL124 Winter Haven, FL156 Kissimmee, FL914 Orlando, FL928

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Spring Hill Bladder Issues Due To Spinal Cord Injury in Spring Hill All conditions

More of FL

Fort Lauderdale1,994 Pembroke Pines1,989 Hollywood1,989 Hialeah1,939 Miami1,913 St. Petersburg1,334 Tampa1,316 Deltona942 Orlando928 Kissimmee914 Jacksonville903 Gainesville543

New paid studies open every week

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