Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/FL/St. Petersburg
Updated November 2026 from ClinicalTrials.gov

Paid Clinical Trials in St. Petersburg, FL

Studies commonly pay $75 to $4,500 per completed study

1,357 clinical trials are currently recruiting participants within 30 miles of St. Petersburg. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,357studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near St. Petersburg right now

Top 25 of 1,357 recruiting studies, sorted by proximity — each links to its official registry page

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A

Von Willebrand Disease, Type 3, Concomitant VWD and Hemophilia Phase 1 Interventional 40 participants sought
St. Joseph's Children's Hospital - Center for Bleeding and Clotting Disorders — Tampa, Florida (16.5 mi) · Sponsor: Bleeding and Clotting Disorders Institute Peoria, Illinois
See eligibility & contact on ClinicalTrials.gov (NCT05500807)

Adaptive Therapy of Vismodegib in Advanced Basal Cell Carcinoma

Advanced Basal Cell Carcinoma EARLY/Phase 1 Interventional 34 participants sought
Moffitt Cancer Center — Tampa, Florida (16.5 mi) · Sponsor: H. Lee Moffitt Cancer Center and Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT05651828)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Johns Hopkins All Children's Hospital — St. Petersburg, Florida (1.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma

Melanoma Stage III, Melanoma Stage IV Phase 2 Interventional 90 participants sought
Moffitt Cancer Center — Tampa, Florida (16.5 mi) · Sponsor: H. Lee Moffitt Cancer Center and Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT06295159)

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC

Metastatic Colorectal Cancer, Hepatocellular Carcinoma Phase 2 Interventional 40 participants sought
Moffitt Cancer Center — Tampa, Florida (16.5 mi) · Sponsor: H. Lee Moffitt Cancer Center and Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT06553885)

A Phase Ib Study of Rezatapopt in Combination With Azacitidine in Patients With TP53Y220C Mutant Myeloid Malignancies (Acute Myeloid Leukemia or Myelodysplastic Syndrome)

Myelodysplastic Syndrome, Acute Myeloid Leukemia Phase 1 Interventional 24 participants sought
Moffitt Cancer Center — Tampa, Florida (16.5 mi) · Sponsor: M.D. Anderson Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT06616636)

Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy

Chronic Graft-versus-host Disease (cGVHD) Phase 2 Interventional 120 participants sought
Moffitt Cancer Center — Tampa, Florida (16.5 mi) · Sponsor: H. Lee Moffitt Cancer Center and Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT06660355)

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

Breast Cancer Phase 3 Interventional 450 participants sought
Moffitt Cancer Center-McKinley Campus — Tampa, Florida (16.5 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06790693)

A Study of HS235 for Treatment of Pulmonary Arterial Hypertension (PAH) in Adults

Pulmonary Arterial Hypertension Phase 1, Phase 2 Interventional 90 participants sought
Investigational Site-102 — Tampa, Florida (16.5 mi) · Sponsor: 35Pharma Inc
See eligibility & contact on ClinicalTrials.gov (NCT07143448)

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
USF Diabetes and Endocrinology Center — Tampa, Florida (16.5 mi) · Sponsor: Medtronic MiniMed, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07228117)

A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)

Multiple Myeloma Phase 1 Interventional 127 participants sought
Moffitt Cancer Center /ID# 279068 — Tampa, Florida (16.5 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT07409246)

Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea

Sleep Apnea, Chronic Nasal Congestion Phase 4 Interventional 52 participants sought
Usf Asthma Allergy and Immunology Cru — Tampa, Florida (16.5 mi) · Sponsor: University of South Florida
See eligibility & contact on ClinicalTrials.gov (NCT02630121)

Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

Generalized Myasthenia Gravis N/A Observational 500 participants sought
Clinical Trial Site — Clearwater, Florida (14.5 mi) · Sponsor: Alexion Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04202341)

Pilot Study to Evaluate the Long-term Chronic Care of Patients Who Could or do Utilize an Osseointegrated Device (OID)

Hearing Loss, Conductive, Hearing Loss, Mixed N/A Observational 50 participants sought
Department of USF Health Otolaryngology; Auditory Rehabilitation & Clinical Trials Lab — Tampa, Florida (16.5 mi) · Sponsor: University of South Florida
See eligibility & contact on ClinicalTrials.gov (NCT04899037)

A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF SHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS

Advanced Solid Tumors Phase 1, Phase 2 Interventional 83 participants sought
Comprehensive Hematology Oncology — St. Petersburg, Florida (1.8 mi) · Sponsor: Jiangsu HengRui Medicine Co., Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT05277168)

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC) Phase 1 Interventional 604 participants sought
Lee Moffitt Cancer Center — Tampa, Florida (16.5 mi) · Sponsor: Revolution Medicines, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06040541)

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Solid Tumor, Adult, Metastatic Breast Cancer Phase 1 Interventional 392 participants sought
Moffitt Cancer Center — Tampa, Florida (16.5 mi) · Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
See eligibility & contact on ClinicalTrials.gov (NCT06625775)

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Breast Neoplasms, Triple Negative Breast Neoplasms Phase 3 Interventional 2,400 participants sought
Florida Cancer Specialists - North ( Site 7002) — St. Petersburg, Florida (1.8 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06966700)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — St. Petersburg, Florida (1.8 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

Urothelial Cancer, Bladder Cancer Phase 2, Phase 3 Interventional 630 participants sought
Research Site — St. Petersburg, Florida (1.8 mi) · Sponsor: Daiichi Sankyo
See eligibility & contact on ClinicalTrials.gov (NCT07129993)

A Study of Buntanetap in Participants With PD

Parkinson's Disease (PD), Deep Brain Stimulation Phase 2, Phase 3 Interventional 500 participants sought
University of South Florida (USF) - University of South Florida College of Medicine - Parkinson's Di — Tampa, Florida (16.5 mi) · Sponsor: Annovis Bio Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07284784)

A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma

Severe Asthma Phase 2 Interventional 512 participants sought
Research site — Tampa, Florida (16.5 mi) · Sponsor: Kinaset Therapeutics Inc
See eligibility & contact on ClinicalTrials.gov (NCT07532265)

AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

Obesity, Overweight Phase 3 Interventional 300 participants sought
DM Clinical — Bradenton, Florida (21.1 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07571109)
Actively enrolling

Studies you may be able to join near St. Petersburg

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in St. Petersburg

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Cliantha Research

★ 4.8
4711 34th St N, St. Petersburg, FL 33714
(727) 362-6358
"This place is great They gea 5stars all the way around"
— Jason Case, 5★

GCP Research

★ 5.0
3455 58th Ave N, St. Petersburg, FL 33714
(727) 520-1427
"Buena clínica research, buenos estudios y el personal un trato excelente"
— Dayetsi Piedra, 5★

IMA Clinical Research

★ 3.0
1530 4th St N, St. Petersburg, FL 33704
(727) 235-7382
"Olga is very good, and the doctor is as well. However, the resources they use, such as the MRI facility (ST Pete MRI), I do not recommend at all. The…"
— Karen Amador, 1★

THEIA Clinical Research

5760 5th Ave N, St. Petersburg, FL 33710
(727) 225-2728

Princeton Consumer Research

★ 4.7
Baypoint Commerce Center, 9600 Koger Blvd N, St. Petersburg, FL 33702
(727) 576-7300
"See articles on the sunscreen testing scandal in Australia, including one on July 3rd, 2025, from the Australian Broadcasting Corporation, titled "Pr…"
— Larry West, 1★

Vantage Clinical Trials (Saint Petersburg)

5800 49th Street N Ste S-108, St. Petersburg, FL 33709
(727) 471-6226

Florida Cancer Specialists & Research Institute - Corporate

★ 5.0
560 Jackson St N, St. Petersburg, FL 33705
"friendly and knowledgeable staff"
— Glenn Harris, 5★

Advent Clinical Research Center

★ 1.0
4820 Park Blvd Ste 2, Pinellas Park, FL 33781
(727) 521-9200
"There needs to be a better picture of your establishment. Not sure if this is right place."
— U.M. Flavien, 1★

Clinical Research of West Florida, Inc - Tampa

★ 4.7
605 N Howard Ave, Tampa, FL 33606
(813) 870-1292
"Clinical research of West Florida is a great place the staff is friendly the nurses they all are great the doctor is very good I enjoyed being there …"
— Kelly Musgrave, 5★

Clinical trials in St. Petersburg: what's recruiting

The St. Petersburg area currently has 1,357 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to St. Petersburg, the most active research areas are:

  • Cancer & Oncology12 studies
  • Lungs & Breathing2 studies
  • Diabetes & Metabolism2 studies
  • Liver & Kidney1 studies
  • Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from St. Petersburg, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in St. Petersburg

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

St. Petersburg participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in St. Petersburg?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in St. Petersburg safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in St. Petersburg?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of St. Petersburg.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in St. Petersburg typically complete one or two studies per year.

Paid clinical trials near St. Petersburg

Other metros within reach

Tampa, FL1,338 Spring Hill, FL116 Lakeland, FL196 Winter Haven, FL166 Leesburg, FL149 Cape Coral, FL236 Kissimmee, FL940 Ocala, FL136

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in St. Petersburg Bladder Issues Due To Spinal Cord Injury in St. Petersburg All conditions

More of FL

Fort Lauderdale2,010 Pembroke Pines2,009 Hollywood2,009 Hialeah1,960 Miami1,931 Tampa1,338 Deltona971 Orlando957 Kissimmee940 Jacksonville920 Gainesville533

New paid studies open every week

Get an email when a new clinical trial starts recruiting within 30 miles of your ZIP code. No spam — only real studies from the NIH registry.

By subscribing you agree to receive study alert emails. Unsubscribe anytime in one click.

Get free trial alerts