Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/FL/Cape Coral
Updated October 2026 from ClinicalTrials.gov

Paid Clinical Trials in Cape Coral, FL

Studies commonly pay $75 to $4,500 per completed study

242 clinical trials are currently recruiting participants within 30 miles of Cape Coral. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

242studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Cape Coral right now

Top 25 of 242 recruiting studies, sorted by proximity — each links to its official registry page

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Fort Myers, Florida (9.7 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06129864)

RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures

Focal Onset Seizures Phase 2 Interventional 216 participants sought
Medsol Clinical Research Center — Port Charlotte, Florida (23.7 mi) · Sponsor: Supernus Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06798896)

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

NSCLC (Non-small Cell Lung Cancer), Non-Small Cell Lung Cancer Phase 3 Interventional 590 participants sought
Florida Cancer Specialists & Research Institute - South — Fort Myers, Florida (9.7 mi) · Sponsor: Revolution Medicines, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06881784)

A Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C Mutation

Advanced Solid Tumors Phase 2 Interventional 14 participants sought
Florida Cancer Specialists - Fort Myers — Fort Myers, Florida (9.7 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07172919)

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Childhood Medulloblastoma Phase 3 Interventional 225 participants sought
Golisano Children's Hospital of Southwest Florida — Fort Myers, Florida (9.7 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT05382338)

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Breast Neoplasms, Triple Negative Breast Neoplasms Phase 3 Interventional 2,400 participants sought
Florida Cancer Specialists - South ( Site 7004) — Fort Myers, Florida (9.7 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06966700)

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

Heart Failure, Acute Heart Failure Phase 3 Interventional 5,200 participants sought
Fort Myers, FL Investigative Site 10076 — Fort Myers, Florida (9.7 mi) · Sponsor: Colorado Prevention Center
See eligibility & contact on ClinicalTrials.gov (NCT06008197)

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

Psychosis Associated With Alzheimer's Disease Phase 3 Interventional 500 participants sought
Local Institution - 1165 — Fort Myers, Florida (9.7 mi) · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See eligibility & contact on ClinicalTrials.gov (NCT06126224)

Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy

Diabetic Peripheral Neuropathic Pain Phase 2 Interventional 300 participants sought
AMR Fort Myers (The Clinical Study Center) — Fort Myers, Florida (9.7 mi) · Sponsor: Vertex Pharmaceuticals Incorporated
See eligibility & contact on ClinicalTrials.gov (NCT06619860)

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

Limited Stage Small Cell Lung Cancer Phase 2 Interventional 250 participants sought
Florida Cancer Specialists - South — Fort Myers, Florida (9.7 mi) · Sponsor: SCRI Development Innovations, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06773910)

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Colon Adenocarcinoma, Rectal Adenocarcinoma Phase 3 Interventional 477 participants sought
Florida Cancer Specialists - South ( Site 7002) — Fort Myers, Florida (9.7 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06997497)

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Mitral Valve Regurgitation N/A Interventional 1,056 participants sought
HealthPark Medical Center — Fort Myers, Florida (9.7 mi) · Sponsor: Medtronic Cardiovascular
See eligibility & contact on ClinicalTrials.gov (NCT03242642)

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Graves' Disease Phase 2 Interventional 240 participants sought
Site Number - 1016 — Port Charlotte, Florida (23.7 mi) · Sponsor: Immunovant Sciences GmbH
See eligibility & contact on ClinicalTrials.gov (NCT06727604)

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis Phase 3 Interventional 762 participants sought
89bio Clinical Study Site — Fort Myers, Florida (9.7 mi) · Sponsor: 89bio, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06419374)

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Colorectal Neoplasms Phase 3 Interventional 1,000 participants sought
Florida Cancer Specialists South — Fort Myers, Florida (9.7 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06662786)

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Heart Failure Phase 3 Interventional 4,200 participants sought
Peace River Cardiovascular Center — Port Charlotte, Florida (23.7 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT06935370)

Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder

Schizophrenia, Bipolar Disorder Phase 3 Interventional 300 participants sought
Royal Palm Clinical Research — Fort Myers, Florida (9.7 mi) · Sponsor: Intra-Cellular Therapies, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06229210)

A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)

Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 600 participants sought
Site 12 — Fort Myers, Florida (9.7 mi) · Sponsor: Merus B.V.
See eligibility & contact on ClinicalTrials.gov (NCT06496178)

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

Ovarian Cancer, Fallopian Tube Cancer Phase 2 Interventional 270 participants sought
544 — Fort Myers, Florida (9.7 mi) · Sponsor: Corcept Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06906341)

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Atherosclerotic Cardiovascular Disease, Overweight Phase 3 Interventional 12,800 participants sought
Alliance for Multispecialty Research - Fort Myers — Fort Myers, Florida (9.7 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037433)

Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)

CIN 2/3, HPV Infection Phase 2 Interventional 78 participants sought
Florida Gynecologic Oncology — Fort Myers, Florida (9.7 mi) · Sponsor: Frantz Viral Therapeutics, LLC
See eligibility & contact on ClinicalTrials.gov (NCT04098744)

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Low Grade Astrocytoma, Low Grade Glioma Phase 3 Interventional 170 participants sought
Golisano Children's Hospital of Southwest Florida — Fort Myers, Florida (9.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04166409)

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute Phase 3 Interventional 600 participants sought
Florida Cancer Specialists & Research Institute — Fort Myers, Florida (9.7 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06852222)
Actively enrolling

Studies you may be able to join near Cape Coral

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Cape Coral

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

AMR Clinical Fort Myers

★ 5.0
13670 Metropolis Ave #105, Fort Myers, FL 33912
(239) 936-4421

Gulfcoast Clinical Research Center

★ 3.9
6150 Diamond Centre Ct #500, Fort Myers, FL 33912
(239) 561-0009
"Don't waste your time. They will take your personal info and complete ignore calls. Beware."
— Brittany Alvarez, 2★

Clinical Trials

2307 Bolado Pkwy, Cape Coral, FL 33990
(239) 383-7062

C & R Research Services USA

★ 5.0
8140 College Pkwy Suite 104, Fort Myers, FL 33919
(239) 400-0224
"Azienda molto professionale ed all avanguardia. Mi sono rivolta a loro e sono stati molto bravi a risolvere il mio problema<br>Consiglio a tutti di r…"
— Daniela, 5★

Neuropsychiatric Research Center of Southwest Florida

★ 4.9
14271 Metropolis Ave, Fort Myers, FL 33912
(239) 939-7777
"Helps people get treatment for Alzheimers while researching and studies are down"
— Deana Rizzo, 5★

Abmed Clinical Research

★ 5.0
1716 Cape Coral Pkwy W #1, Cape Coral, FL 33914
(239) 471-7595
"I highly recommend the clinic… Mildred was very professional, the lady who attended to us and helped us throughout the entire process…"
— Claudia Rosich, 5★

S&D Clinical Research

★ 5.0
8140 College Pkwy Suite 104, Fort Myers, FL 33919
(239) 202-8876
"I had an amazing experience with everyone at S&D Clinical research and will definitely be returning soon."
— Aleida Delgado, 5★

Florida Cancer Specialists & Research Institute

★ 4.6 (737 reviews)
1030 Commerce Creek Blvd, Cape Coral, FL 33909
(239) 997-3081
"I moved to cape coral from Carmel in where I was treated by dr Gupta oncologist associated with Saint Francis hospital. I have to say walking into FL…"
— Roman Korbiak, 2★

Florida Cancer Specialists & Research Institute

★ 4.6 (349 reviews)
1708 Cape Coral Pkwy W #10, Cape Coral, FL 33914
(239) 541-4633
"While nurse staff is caring and supportive, office staff is unhelpful in and current doctors do not seem to care about patient wishes. It seems that …"
— Brooke Paprocki, 1★

Clinical trials in Cape Coral: what's recruiting

The Cape Coral area currently has 242 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Cape Coral, the most active research areas are:

  • Cancer & Oncology11 studies
  • Diabetes & Metabolism4 studies
  • Heart & Vascular3 studies
  • Brain & Mental Health2 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from Cape Coral, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Cape Coral

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Cape Coral participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Cape Coral?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Cape Coral?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Cape Coral?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Cape Coral.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Cape Coral typically complete one or two studies per year.

Paid clinical trials near Cape Coral

Other metros within reach

Bonita Springs, FL300 St. Petersburg, FL1,354 Winter Haven, FL167 Lakeland, FL200 Tampa, FL1,335 Port St. Lucie, FL103 Kissimmee, FL934 Pembroke Pines, FL2,002

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Cape Coral Bladder Issues Due To Spinal Cord Injury in Cape Coral All conditions

More of FL

Fort Lauderdale2,008 Pembroke Pines2,002 Hollywood2,002 Hialeah1,956 Miami1,931 St. Petersburg1,354 Tampa1,335 Deltona966 Orlando950 Kissimmee934 Jacksonville924 Gainesville532

New paid studies open every week

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