Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/FL/Cape Coral
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Cape Coral, FL

Studies commonly pay $75 to $4,500 per completed study

246 clinical trials are currently recruiting participants within 30 miles of Cape Coral. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

246studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Cape Coral right now

Top 25 of 246 recruiting studies, sorted by proximity — each links to its official registry page

A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED

Persistent Corneal Epithelial Defect Phase 2 Interventional 84 participants sought
Glaukos Investigative Site — Fort Myers, Florida (9.7 mi) · Sponsor: Glaukos Corporation
See eligibility & contact on ClinicalTrials.gov (NCT05966493)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Golisano Children's Hospital of Southwest Florida — Fort Myers, Florida (9.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Fort Myers, Florida (9.7 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06129864)

The Purpose of This Study is to Evaluate Efficacy and Safety of NT-101 Eye Drops in Patients With Wet Age-Related Macular Degeneration (AMD)

Wet Age Related Macular Degeneration Phase 2 Interventional 66 participants sought
Advanced Retina Institute — Bonita Springs, Florida (25.0 mi) · Sponsor: NexThera Co., Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT07811726)

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Lymphoma, Non-Hodgkin, Multiple Myeloma Phase 2 Interventional 4,200 participants sought
Florida Cancer Specialists South / Sarah Cannon Research Institute — Cape Coral, Florida (6.3 mi) · Sponsor: American Society of Clinical Oncology
See eligibility & contact on ClinicalTrials.gov (NCT02693535)

Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)

CIN 2/3, HPV Infection Phase 2 Interventional 78 participants sought
Florida Gynecologic Oncology — Fort Myers, Florida (9.7 mi) · Sponsor: Frantz Viral Therapeutics, LLC
See eligibility & contact on ClinicalTrials.gov (NCT04098744)

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer Phase 3 Interventional 600 participants sought
Florida Cancer Specialists - SOUTH - SCRI - PPDS — Fort Myers, Florida (9.7 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06793215)

HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes

Type 2 Diabetes Phase 2 Interventional 300 participants sought
Southwest General Healthcare Center — Fort Myers, Florida (9.7 mi) · Sponsor: Housey Healthcare ULC
See eligibility & contact on ClinicalTrials.gov (NCT07546929)

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

Psychosis Associated With Alzheimer's Disease Phase 3 Interventional 500 participants sought
Local Institution - 1165 — Fort Myers, Florida (9.7 mi) · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See eligibility & contact on ClinicalTrials.gov (NCT06126224)

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis Phase 3 Interventional 2,150 participants sought
Akero Clinical Study Site — Fort Myers, Florida (9.7 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06528314)

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

Limited Stage Small Cell Lung Cancer Phase 2 Interventional 250 participants sought
Florida Cancer Specialists - South — Fort Myers, Florida (9.7 mi) · Sponsor: SCRI Development Innovations, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06773910)

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

Atherosclerotic Cardiovascular Disease (ASCVD) Phase 3 Interventional 340 participants sought
Peace River Cardiovascular Center — Port Charlotte, Florida (23.7 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06813911)

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Colon Adenocarcinoma, Rectal Adenocarcinoma Phase 3 Interventional 477 participants sought
Florida Cancer Specialists - South ( Site 7002) — Fort Myers, Florida (9.7 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06997497)

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Mitral Valve Regurgitation N/A Interventional 1,056 participants sought
HealthPark Medical Center — Fort Myers, Florida (9.7 mi) · Sponsor: Medtronic Cardiovascular
See eligibility & contact on ClinicalTrials.gov (NCT03242642)

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Advanced Non-Small Cell Lung Cancer, Non-Small Cell Lung Cancer Phase 3 Interventional 1,410 participants sought
Florida Cancer Specialists — Cape Coral, Florida (6.3 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07222566)

Quality of End-of-Life Care for Children With Cancer

Childhood Hematopoietic and Lymphatic System Neoplasm, Childhood Malignant Solid Neoplasm N/A Observational 2,425 participants sought
Golisano Children's Hospital of Southwest Florida — Fort Myers, Florida (9.7 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT07412002)

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

Obesity, Overweight Phase 3 Interventional 1,100 participants sought
ACCOMPLISH-2 Research Site — Fort Myers, Florida (9.7 mi) · Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT07654374)

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

Low Grade Serous Ovarian Cancer Phase 3 Interventional 270 participants sought
Florida Cancer Specialists - South — Fort Myers, Florida (9.7 mi) · Sponsor: Verastem, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06072781)

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Colorectal Neoplasms Phase 3 Interventional 1,000 participants sought
Florida Cancer Specialists South — Fort Myers, Florida (9.7 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06662786)

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Diabetes Mellitus, Type 2, Hypertension Phase 3 Interventional 11,800 participants sought
Covenant Metabolic Specialists, LLC - Fort Myers — Fort Myers, Florida (9.7 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07064473)

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

Psychosis Associated With Alzheimer's Disease Phase 3 Interventional 410 participants sought
Local Institution - 1020 — Bonita Springs, Florida (25.0 mi) · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See eligibility & contact on ClinicalTrials.gov (NCT05511363)

A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)

Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 600 participants sought
Site 12 — Fort Myers, Florida (9.7 mi) · Sponsor: Merus B.V.
See eligibility & contact on ClinicalTrials.gov (NCT06496178)
Actively enrolling

Studies you may be able to join near Cape Coral

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Cape Coral

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

AMR Clinical Fort Myers

★ 5.0
13670 Metropolis Ave #105, Fort Myers, FL 33912
(239) 936-4421

Gulfcoast Clinical Research Center

★ 3.9
6150 Diamond Centre Ct #500, Fort Myers, FL 33912
(239) 561-0009
"Don't waste your time. They will take your personal info and complete ignore calls. Beware."
— Brittany Alvarez, 2★

Clinical Trials

2307 Bolado Pkwy, Cape Coral, FL 33990
(239) 383-7062

C & R Research Services USA

★ 5.0
8140 College Pkwy Suite 104, Fort Myers, FL 33919
(239) 400-0224
"Azienda molto professionale ed all avanguardia. Mi sono rivolta a loro e sono stati molto bravi a risolvere il mio problema<br>Consiglio a tutti di r…"
— Daniela, 5★

Neuropsychiatric Research Center of Southwest Florida

★ 4.9
14271 Metropolis Ave, Fort Myers, FL 33912
(239) 939-7777
"Helps people get treatment for Alzheimers while researching and studies are down"
— Deana Rizzo, 5★

Abmed Clinical Research

★ 5.0
1716 Cape Coral Pkwy W #1, Cape Coral, FL 33914
(239) 471-7595
"I highly recommend the clinic… Mildred was very professional, the lady who attended to us and helped us throughout the entire process…"
— Claudia Rosich, 5★

S&D Clinical Research

★ 5.0
8140 College Pkwy Suite 104, Fort Myers, FL 33919
(239) 202-8876
"I had an amazing experience with everyone at S&D Clinical research and will definitely be returning soon."
— Aleida Delgado, 5★

Florida Cancer Specialists & Research Institute

★ 4.6 (737 reviews)
1030 Commerce Creek Blvd, Cape Coral, FL 33909
(239) 997-3081
"I moved to cape coral from Carmel in where I was treated by dr Gupta oncologist associated with Saint Francis hospital. I have to say walking into FL…"
— Roman Korbiak, 2★

Florida Cancer Specialists & Research Institute

★ 4.6 (349 reviews)
1708 Cape Coral Pkwy W #10, Cape Coral, FL 33914
(239) 541-4633
"While nurse staff is caring and supportive, office staff is unhelpful in and current doctors do not seem to care about patient wishes. It seems that …"
— Brooke Paprocki, 1★

Clinical trials in Cape Coral: what's recruiting

The Cape Coral area currently has 246 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Cape Coral, the most active research areas are:

  • Cancer & Oncology10 studies
  • Diabetes & Metabolism5 studies
  • Brain & Mental Health2 studies
  • Heart & Vascular2 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from Cape Coral, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Cape Coral

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Cape Coral participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Cape Coral?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Cape Coral?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Cape Coral?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Cape Coral.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Cape Coral typically complete one or two studies per year.

Paid clinical trials near Cape Coral

Other metros within reach

Bonita Springs, FL296 St. Petersburg, FL1,353 Winter Haven, FL159 Lakeland, FL191 Tampa, FL1,335 Port St. Lucie, FL105 Kissimmee, FL927 Pembroke Pines, FL1,980

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Cape Coral Bladder Issues Due To Spinal Cord Injury in Cape Coral All conditions

More of FL

Fort Lauderdale1,987 Pembroke Pines1,980 Hollywood1,980 Hialeah1,934 Miami1,911 St. Petersburg1,353 Tampa1,335 Deltona953 Orlando942 Kissimmee927 Jacksonville916 Gainesville538

New paid studies open every week

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