Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/FL/Bonita Springs
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Bonita Springs, FL

Studies commonly pay $75 to $4,500 per completed study

298 clinical trials are currently recruiting participants within 30 miles of Bonita Springs. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

298studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Bonita Springs right now

Top 25 of 298 recruiting studies, sorted by proximity — each links to its official registry page

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Golisano Children's Hospital of Southwest Florida — Fort Myers, Florida (18.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Fort Myers, Florida (18.7 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06129864)

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought
Retina Group of Florida - Fort Myers Retina Center — Fort Myers, Florida (18.7 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07553429)

Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction, Concentric Hypertrophy N/A Interventional 105 participants sought
NCH Heart Institute — Naples, Florida (14.8 mi) · Sponsor: Medtronic Cardiac Rhythm and Heart Failure
See eligibility & contact on ClinicalTrials.gov (NCT05839730)

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis Phase 2 Interventional 168 participants sought
US Renal Care - Fort Myers South — Fort Myers, Florida (18.7 mi) · Sponsor: R1 Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06712654)

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer Phase 3 Interventional 600 participants sought
Florida Cancer Specialists - SOUTH - SCRI - PPDS — Fort Myers, Florida (18.7 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06793215)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Fort Myers, Florida (18.7 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Diabetes Mellitus, Type 2, Hypertension Phase 3 Interventional 11,800 participants sought
Advanced Research for Health Improvement, LLC — Naples, Florida (14.8 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07064473)

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Lymphoma, Non-Hodgkin, Multiple Myeloma Phase 2 Interventional 4,200 participants sought
Florida Cancer Specialists South / Sarah Cannon Research Institute — Bonita Springs, Florida (1.2 mi) · Sponsor: American Society of Clinical Oncology
See eligibility & contact on ClinicalTrials.gov (NCT02693535)

Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients

Irritability Associated With Autism Spectrum Disorder Phase 3 Interventional 160 participants sought
Royal Palm Clinical Research — Fort Myers, Florida (18.7 mi) · Sponsor: Intra-Cellular Therapies, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06690398)

Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

Viral Pneumonia Phase 2 Interventional 550 participants sought
NCH Pulmonary Critical Care — Naples, Florida (14.8 mi) · Sponsor: Synairgen Research Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT06999603)

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

Major Depressive Disorder Phase 2 Interventional 164 participants sought
Aqualane Clinical Research — Naples, Florida (14.8 mi) · Sponsor: Syndeio Biosciences, Inc
See eligibility & contact on ClinicalTrials.gov (NCT07115329)

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Phase 3 Interventional 1,200 participants sought
Florida Cancer Specialists - South ( Site 7001) — Fort Myers, Florida (18.7 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06136559)

A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

Bronchiectasis With Pseudomonas Aeruginosa Colonization Phase 2 Interventional 435 participants sought
Research Site — Naples, Florida (14.8 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07088926)

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Advanced Non-Small Cell Lung Cancer, Non-Small Cell Lung Cancer Phase 3 Interventional 1,410 participants sought
Florida Cancer Specialists — Bonita Springs, Florida (1.2 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07222566)

HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes

Type 2 Diabetes Phase 2 Interventional 300 participants sought
Southwest General Healthcare Center — Fort Myers, Florida (18.7 mi) · Sponsor: Housey Healthcare ULC
See eligibility & contact on ClinicalTrials.gov (NCT07546929)

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought
GenesisCare USA - FGO — Fort Myers, Florida (18.7 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04251052)

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Malignant Glioma Phase 1, Phase 2 Interventional 132 participants sought
Golisano Children's Hospital of Southwest Florida — Fort Myers, Florida (18.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05099003)

A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)

Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 600 participants sought
Site 12 — Fort Myers, Florida (18.7 mi) · Sponsor: Merus B.V.
See eligibility & contact on ClinicalTrials.gov (NCT06496178)

A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration

Neovascular Age-related Macular Degeneration, nAMD Phase 3 Interventional 304 participants sought
Retina Consultants of Southwest Florida - Naples — Naples, Florida (14.8 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07614776)

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Colon Adenocarcinoma, Rectal Adenocarcinoma Phase 3 Interventional 477 participants sought
Florida Cancer Specialists - South ( Site 7002) — Fort Myers, Florida (18.7 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06997497)

A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio

Geographic Atrophy Secondary to Age-related Macular Degeneration Phase 2 Interventional 240 participants sought
Advance Retina Institute — Bonita Springs, Florida (1.2 mi) · Sponsor: Apellis Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07215390)
Actively enrolling

Studies you may be able to join near Bonita Springs

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Bonita Springs

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Envision Trials

★ 5.0
3421 Bonita Beach Rd SW #401, Bonita Springs, FL 34134
(941) 677-0087
"The doctors are very good and the benefits are excellent. I recommend them."
— zulema fontaine lovelle, 5★

AMR Clinical Fort Myers

★ 5.0
13670 Metropolis Ave #105, Fort Myers, FL 33912
(239) 936-4421

Florida Cancer Specialists & Research Institute

★ 4.7 (429 reviews)
9776 Bonita Beach Rd SE #201a, Bonita Springs, FL 34135
(239) 947-3092
"Dr. Rubin and his staff are excellent. Attentive and always available to talk, text, or meet with you. This facility is thorough. Your first visit co…"
— Scott Lepore, 5★

Gulfcoast Clinical Research Center

★ 3.9
6150 Diamond Centre Ct #500, Fort Myers, FL 33912
(239) 561-0009
"Don't waste your time. They will take your personal info and complete ignore calls. Beware."
— Brittany Alvarez, 2★

Neuropsychiatric Research Center of Southwest Florida

★ 4.9
14271 Metropolis Ave, Fort Myers, FL 33912
(239) 939-7777
"Helps people get treatment for Alzheimers while researching and studies are down"
— Deana Rizzo, 5★

C & R Research Services USA

★ 5.0
8140 College Pkwy Suite 104, Fort Myers, FL 33919
(239) 400-0224
"Azienda molto professionale ed all avanguardia. Mi sono rivolta a loro e sono stati molto bravi a risolvere il mio problema<br>Consiglio a tutti di r…"
— Daniela, 5★

Aqualane Clinical Research

★ 5.0
3200 Bailey Ln Ste 250, Naples, FL 34105
(239) 529-6780
"Kind and professional staff members. They took the time to explain all the questions and concerns I had.<br>I highly recommend to anyone who would be…"
— Dobromira Komaeva, 5★

Florida Cancer Specialists & Research Institute

★ 4.8 (380 reviews)
8440 Murano Del Lago Dr, Bonita Springs, FL 34135
(239) 221-5402
"Dr. Khan is great! Office and communication of office is horrible. Delays for care and test results, no call backs or portal message answers. Very p…"
— Dawn Saeger, 1★

S&D Clinical Research

★ 5.0
8140 College Pkwy Suite 104, Fort Myers, FL 33919
(239) 202-8876
"I had an amazing experience with everyone at S&D Clinical research and will definitely be returning soon."
— Aleida Delgado, 5★

Clinical trials in Bonita Springs: what's recruiting

The Bonita Springs area currently has 298 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Bonita Springs, the most active research areas are:

  • Cancer & Oncology11 studies
  • Diabetes & Metabolism3 studies
  • Heart & Vascular3 studies
  • Liver & Kidney1 studies
  • Brain & Mental Health1 studies

Every listing shows the study phase, the recruiting site and its distance from Bonita Springs, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Bonita Springs

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Bonita Springs participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Bonita Springs pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Bonita Springs?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Bonita Springs?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Bonita Springs?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Bonita Springs.

Paid clinical trials near Bonita Springs

Other metros within reach

Cape Coral, FL247 Pembroke Pines, FL1,988 Hialeah, FL1,939 Hollywood, FL1,988 Fort Lauderdale, FL1,996 Winter Haven, FL159 Port St. Lucie, FL106 Miami, FL1,917

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Bonita Springs Bladder Issues Due To Spinal Cord Injury in Bonita Springs All conditions

More of FL

Fort Lauderdale1,996 Pembroke Pines1,988 Hollywood1,988 Hialeah1,939 Miami1,917 St. Petersburg1,350 Tampa1,331 Deltona946 Orlando937 Kissimmee924 Jacksonville910 Gainesville540

New paid studies open every week

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