Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/HI/Honolulu
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Honolulu, HI

Studies commonly pay $75 to $4,500 per completed study

201 clinical trials are currently recruiting participants within 30 miles of Honolulu. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

201studies recruiting
9+research centers nearby
3condition categories
Live from the NIH registry

Studies recruiting near Honolulu right now

Top 25 of 201 recruiting studies, sorted by proximity — each links to its official registry page

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

Prediabetic State, Atherosclerosis Phase 4 Interventional 7,410 participants sought
VA Pacific Islands Health Care System, Honolulu, HI — Honolulu, Hawaii (1.7 mi) · Sponsor: VA Office of Research and Development

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Kapiolani Medical Center for Women and Children — Honolulu, Hawaii (1.7 mi) · Sponsor: National Cancer Institute (NCI)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Honolulu, Hawaii (1.7 mi) · Sponsor: Sameek Roychowdhury

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma, Stage II Pancreatic Cancer AJCC v8 Phase 3 Interventional 356 participants sought
Hawaii Cancer Care Inc - Waterfront Plaza — Honolulu, Hawaii (1.7 mi) · Sponsor: NRG Oncology

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Solid Tumors, Hematologic Malignancies Phase 3 Interventional 3,500 participants sought
Kaiser Permanente Moanalua Medical Center ( Site 0063) — Honolulu, Hawaii (1.7 mi) · Sponsor: Merck Sharp & Dohme LLC

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism Phase 2, Phase 3 Interventional 2,800 participants sought
Pacific Diabetes & Endocrine Center /ID# 259030 — Honolulu, Hawaii (1.7 mi) · Sponsor: AbbVie

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Honolulu, Hawaii (1.7 mi) · Sponsor: AstraZeneca

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Lymphoma, Non-Hodgkin, Multiple Myeloma Phase 2 Interventional 4,200 participants sought
The Queen's Medical Center - POB I — Honolulu, Hawaii (1.7 mi) · Sponsor: American Society of Clinical Oncology

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 189 participants sought
Hawaii Cancer Care Inc - Waterfront Plaza — Honolulu, Hawaii (1.7 mi) · Sponsor: ECOG-ACRIN Cancer Research Group

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
Hawaii Cancer Care Inc - Waterfront Plaza — Honolulu, Hawaii (1.7 mi) · Sponsor: National Cancer Institute (NCI)

Function After Anterior Cervical Discectomy and Fusion Surgery: Timing of Physical Therapy

Cervical Spine Degeneration, ACDF Surgery N/A Interventional 76 participants sought
Tripler Army Medical Center — Honolulu, Hawaii (1.7 mi) · Sponsor: Vanderbilt University Medical Center

Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy

Estrogen Receptor Negative, HER2 Positive Breast Carcinoma N/A Interventional 120 participants sought
Queen's Medical Center — Honolulu, Hawaii (1.7 mi) · Sponsor: M.D. Anderson Cancer Center

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

Metastatic Salivary Gland Carcinoma, Recurrent Salivary Gland Carcinoma Phase 2 Interventional 146 participants sought
Kaiser Permanente Moanalua Medical Center — Honolulu, Hawaii (1.7 mi) · Sponsor: NRG Oncology

Education & Mentorship of Advanced Practice Providers to Increase Community-based Research Within the NCORP Network, COACH-APP Trial

Other N/A Interventional 97 participants sought
Queen's Medical Center — Honolulu, Hawaii (1.7 mi) · Sponsor: Wake Forest University Health Sciences

Multisite Advancement of Research on Chronic Posttraumatic Headache

Posttraumatic Headache N/A Interventional 525 participants sought
Tripler Army Medical Center (Desmond Doss Health Clinic, Schofield Barracks) — Honolulu, Hawaii (1.7 mi) · Sponsor: The University of Texas Health Science Center at San Antonio

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma, Stage I Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8 Phase 3 Interventional 228 participants sought
Kaiser Permanente Moanalua Medical Center — Honolulu, Hawaii (1.7 mi) · Sponsor: Alliance for Clinical Trials in Oncology

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,209 participants sought
Hawaii Cancer Care Inc - Waterfront Plaza — Honolulu, Hawaii (1.7 mi) · Sponsor: NRG Oncology

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

B Acute Lymphoblastic Leukemia Associated With Down Syndrome, Down Syndrome N/A Observational 330 participants sought
Kapiolani Medical Center for Women and Children — Honolulu, Hawaii (1.7 mi) · Sponsor: Children's Oncology Group

Poi for Mama: a Pilot to Improve Maternal Microbiome and Gestational Diabetes Risk

Gestational Diabetes Mellitus (GDM), Pregnancy N/A Interventional 50 participants sought
University of Hawai'i Cancer Center — Honolulu, Hawaii (1.7 mi) · Sponsor: University of Hawaii

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Anaplastic Kidney Wilms Tumor, Recurrent Kidney Wilms Tumor Phase 2 Interventional 256 participants sought
Kapiolani Medical Center for Women and Children — Honolulu, Hawaii (1.7 mi) · Sponsor: Children's Oncology Group

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients

Epilepsy, Healthy Volunteer Phase 1 Interventional 88 participants sought
Hawaii Pacific Neuroscience, Comprehensive Epilepsy Center — Honolulu, Hawaii (1.7 mi) · Sponsor: Suninflam Inc

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Hematologic Malignancies, Inherited Disorders of Metabolism N/A Observational 99,999 participants sought
Kapiolani Medical Center for Women and Children — Honolulu, Hawaii (1.7 mi) · Sponsor: Center for International Blood and Marrow Transplant Research

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

Colorectal Cancer Stage II, Colorectal Cancer Stage III Phase 3 Interventional 1,057 participants sought
Hawaii Cancer Care Inc - Waterfront Plaza — Honolulu, Hawaii (1.7 mi) · Sponsor: SWOG Cancer Research Network
Actively enrolling

Studies you may be able to join near Honolulu

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Google-rated

Top-rated research centers in Honolulu

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Hawaii Clinical Research

1286 Queen Emma St, Honolulu, HI 96813
(808) 538-2880

East-West Medical Research Institute

★ 3.0
1585 Kapiolani Blvd, Honolulu, HI 96814
(808) 440-4426
"I love the respect and honor that the staff provides to the research participants!!!!! Make a different and get involved!!! You will not regret being…"
— Lisa Romano, 5★

Queen's Center for Biomedical Research

UH Tower, 1356 Lusitana St #8, Honolulu, HI 96813
(808) 691-4976

Hawaii Medical Research Center

★ 5.0
1401 S Beretania St. Ste 460, Honolulu, HI 96814
+81 3-6264-4413
"This was my first overseas training session and my first time taking a Cadaver course.<br>The facilities and equipment were excellent, and I was very…"
— 南真, 5★

Shepherd Research Lab

★ 3.7
701 Ilalo St, Honolulu, HI 96813
(808) 440-5230
"regarding my appointment that was rescheduled without prior notice. There were plenty of open appointment times earlier in the month, yet I was moved…"
— Juan Galindo, 1★

Pacific Health Research and Education Institute

3375 Koapaka St I-540, Honolulu, HI 96819
(808) 524-4411

Hawaii Pacific Neuroscience

★ 4.4
2230 Liliha St #104, Honolulu, HI 96817
(808) 261-4476
"Every person we've interacted with in HPN has been so kind and easy to work with. Jerry our EEG tech made the entire process so smooth, he kept the e…"
— Jocelyn Sasso, 5★

University Health Partners of Hawaii

★ 4.0
677 Ala Moana Blvd #1001, Honolulu, HI 96813
(808) 469-4900
"Hello and welcome to our shop. We do offer deescreet fast , safe and relaible services to our clients. Hit us up on telegram @chapo_exotics for good …"
— Frank Anderson, 4★

Neuroscience Institute Outpatient Center - The Queen’s Medical Center

550 S Beretania St. Suites 405, 503 & 510, Honolulu, HI 96813
(808) 691-8866

Clinical trials in Honolulu: what's recruiting

The Honolulu area currently has 201 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Honolulu, the most active research areas are:

  • Cancer & Oncology18 studies
  • Diabetes & Metabolism2 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from Honolulu, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Honolulu

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Honolulu participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Honolulu pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Honolulu?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Honolulu safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Honolulu, HI?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Honolulu typically complete one or two studies per year.

Paid clinical trials near Honolulu

Other metros within reach

New paid studies open every week

Get an email when a new clinical trial starts recruiting within 30 miles of your ZIP code. No spam — only real studies from the NIH registry.

Get free trial alerts