Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/HI/Honolulu
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Honolulu, HI

Studies commonly pay $75 to $4,500 per completed study

201 clinical trials are currently recruiting participants within 30 miles of Honolulu. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

201studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Honolulu right now

Top 25 of 201 recruiting studies, sorted by proximity — each links to its official registry page

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Lymphoma, Non-Hodgkin, Multiple Myeloma Phase 2 Interventional 4,200 participants sought
The Queen's Medical Center - POB I — Honolulu, Hawaii (1.7 mi) · Sponsor: American Society of Clinical Oncology

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

Prediabetic State, Atherosclerosis Phase 4 Interventional 7,410 participants sought
VA Pacific Islands Health Care System, Honolulu, HI — Honolulu, Hawaii (1.7 mi) · Sponsor: VA Office of Research and Development

Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study

Colorectal Adenocarcinoma, Stage I Colorectal Cancer AJCC v8 N/A Observational 1,000 participants sought
The Queen's Medical Center — Honolulu, Hawaii (1.7 mi) · Sponsor: M.D. Anderson Cancer Center

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Kapiolani Medical Center for Women and Children — Honolulu, Hawaii (1.7 mi) · Sponsor: National Cancer Institute (NCI)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Honolulu, Hawaii (1.7 mi) · Sponsor: Sameek Roychowdhury

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Solid Tumors, Hematologic Malignancies Phase 3 Interventional 3,500 participants sought
Kaiser Permanente Moanalua Medical Center ( Site 0063) — Honolulu, Hawaii (1.7 mi) · Sponsor: Merck Sharp & Dohme LLC

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism Phase 2, Phase 3 Interventional 2,800 participants sought
Pacific Diabetes & Endocrine Center /ID# 259030 — Honolulu, Hawaii (1.7 mi) · Sponsor: AbbVie

The PROmoting Pain Self-Management (PROs) Trial: Holistic Pain Care in the Military Health System

Chronic Pain, Musculoskeletal Pain N/A Interventional 608 participants sought
Desmond Doss Health Clinic — Schofield Barracks, Hawaii (18.3 mi) · Sponsor: Brooke Army Medical Center

Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular Degeneration

Neovascular Age-Related Macular Degeneration (nAMD) Wet AMD Phase 2 Interventional 15 participants sought
Adverum site 149 — ‘Aiea, Hawaii (6.7 mi) · Sponsor: Adverum Biotechnologies, Inc.

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 626 participants sought
Local Institution - 007-897 — Honolulu, Hawaii (1.7 mi) · Sponsor: Mirati Therapeutics Inc.

Function After Anterior Cervical Discectomy and Fusion Surgery: Timing of Physical Therapy

Cervical Spine Degeneration, ACDF Surgery N/A Interventional 76 participants sought
Tripler Army Medical Center — Honolulu, Hawaii (1.7 mi) · Sponsor: Vanderbilt University Medical Center

Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

AMI Cardiogenic Shock N/A Observational 350 participants sought
Straub Benioff Medical Center — Honolulu, Hawaii (1.7 mi) · Sponsor: Abiomed Inc.

Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy

Estrogen Receptor Negative, HER2 Positive Breast Carcinoma N/A Interventional 120 participants sought
Queen's Medical Center — Honolulu, Hawaii (1.7 mi) · Sponsor: M.D. Anderson Cancer Center

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Low Grade Astrocytoma, Low Grade Glioma Phase 3 Interventional 170 participants sought
Kapiolani Medical Center for Women and Children — Honolulu, Hawaii (1.7 mi) · Sponsor: National Cancer Institute (NCI)

A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight

Overweight, Obesity Phase 3 Interventional 285 participants sought
East West Med Res Inst — Honolulu, Hawaii (1.7 mi) · Sponsor: Novo Nordisk A/S

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Phase 1, Phase 2 Interventional 960 participants sought
Kapiolani Medical Center for Women and Children — Honolulu, Hawaii (1.7 mi) · Sponsor: PedAL BCU, LLC

A Prospective Study to Develop and Clinically Validate an in Vitro Diagnostic Medical Device That Uses Blood to Classify Patients at High Risk for Breast Cancer

Breast Neoplasm N/A Observational 330 participants sought
Univercity of Hawaii Cancer Center — Honolulu, Hawaii (1.7 mi) · Sponsor: EXoPERT

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Diabetes Mellitus, Type 2, Hypertension Phase 3 Interventional 11,800 participants sought
Pacific Diabetes & Endocrine Center — Honolulu, Hawaii (1.7 mi) · Sponsor: Boehringer Ingelheim

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

Obesity, Overweight Phase 3 Interventional 3,200 participants sought
East-West Medical Research — Honolulu, Hawaii (1.7 mi) · Sponsor: Amgen

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 335 participants sought
Hawaii Cancer Care Inc - Waterfront Plaza — Honolulu, Hawaii (1.7 mi) · Sponsor: National Cancer Institute (NCI)

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

Locally Advanced Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8 Phase 3 Interventional 474 participants sought
Hawaii Cancer Care Inc - Waterfront Plaza — Honolulu, Hawaii (1.7 mi) · Sponsor: NRG Oncology

Poi for Mama: a Pilot to Improve Maternal Microbiome and Gestational Diabetes Risk

Gestational Diabetes Mellitus (GDM), Pregnancy N/A Interventional 50 participants sought
University of Hawai'i Cancer Center — Honolulu, Hawaii (1.7 mi) · Sponsor: University of Hawaii

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Anaplastic Kidney Wilms Tumor, Recurrent Kidney Wilms Tumor Phase 2 Interventional 256 participants sought
Kapiolani Medical Center for Women and Children — Honolulu, Hawaii (1.7 mi) · Sponsor: Children's Oncology Group

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

Adjustment Disorder Phase 2 Interventional 100 participants sought
Hawaii Pacific Neuroscience — Honolulu, Hawaii (1.7 mi) · Sponsor: Reunion Neuroscience Inc
Actively enrolling

Studies you may be able to join near Honolulu

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Google-rated

Top-rated research centers in Honolulu

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Hawaii Clinical Research

1286 Queen Emma St, Honolulu, HI 96813
(808) 538-2880

East-West Medical Research Institute

★ 3.0
1585 Kapiolani Blvd, Honolulu, HI 96814
(808) 440-4426
"I love the respect and honor that the staff provides to the research participants!!!!! Make a different and get involved!!! You will not regret being…"
— Lisa Romano, 5★

Queen's Center for Biomedical Research

UH Tower, 1356 Lusitana St #8, Honolulu, HI 96813
(808) 691-4976

Hawaii Medical Research Center

★ 5.0
1401 S Beretania St. Ste 460, Honolulu, HI 96814
+81 3-6264-4413
"This was my first overseas training session and my first time taking a Cadaver course.<br>The facilities and equipment were excellent, and I was very…"
— 南真, 5★

Shepherd Research Lab

★ 3.7
701 Ilalo St, Honolulu, HI 96813
(808) 440-5230
"regarding my appointment that was rescheduled without prior notice. There were plenty of open appointment times earlier in the month, yet I was moved…"
— Juan Galindo, 1★

Pacific Health Research and Education Institute

3375 Koapaka St I-540, Honolulu, HI 96819
(808) 524-4411

Hawaii Pacific Neuroscience

★ 4.4
2230 Liliha St #104, Honolulu, HI 96817
(808) 261-4476
"Every person we've interacted with in HPN has been so kind and easy to work with. Jerry our EEG tech made the entire process so smooth, he kept the e…"
— Jocelyn Sasso, 5★

University Health Partners of Hawaii

★ 4.0
677 Ala Moana Blvd #1001, Honolulu, HI 96813
(808) 469-4900
"Hello and welcome to our shop. We do offer deescreet fast , safe and relaible services to our clients. Hit us up on telegram @chapo_exotics for good …"
— Frank Anderson, 4★

Neuroscience Institute Outpatient Center - The Queen’s Medical Center

550 S Beretania St. Suites 405, 503 & 510, Honolulu, HI 96813
(808) 691-8866

Clinical trials in Honolulu: what's recruiting

The Honolulu area currently has 201 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Honolulu, the most active research areas are:

  • Cancer & Oncology13 studies
  • Diabetes & Metabolism5 studies
  • Heart & Vascular3 studies
  • Liver & Kidney2 studies

Every listing shows the study phase, the recruiting site and its distance from Honolulu, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Honolulu

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Honolulu participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Honolulu pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Honolulu?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Honolulu safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Honolulu, HI?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Honolulu typically complete one or two studies per year.

Paid clinical trials near Honolulu

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