Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/SC/Columbia
Updated October 2026 from ClinicalTrials.gov

Paid Clinical Trials in Columbia, SC

Studies commonly pay $75 to $4,500 per completed study

190 clinical trials are currently recruiting participants within 30 miles of Columbia. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

190studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Columbia right now

Top 25 of 190 recruiting studies, sorted by proximity — each links to its official registry page

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Childhood Medulloblastoma Phase 3 Interventional 225 participants sought
Prisma Health Richland Hospital — Columbia, South Carolina (7.9 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT05382338)

Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments

Mild-moderate Cognitive Impairment N/A Interventional 50 participants sought
Arnold School of Public Health — Columbia, South Carolina (7.9 mi) · Sponsor: University of South Carolina
See eligibility & contact on ClinicalTrials.gov (NCT06799429)

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Low Grade Astrocytoma, Low Grade Glioma Phase 3 Interventional 170 participants sought
Prisma Health Richland Hospital — Columbia, South Carolina (7.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04166409)

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Phase 1, Phase 2 Interventional 960 participants sought
Prisma Health Richland Hospital — Columbia, South Carolina (7.9 mi) · Sponsor: PedAL BCU, LLC
See eligibility & contact on ClinicalTrials.gov (NCT04726241)

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Heart Failure Phase 3 Interventional 11,300 participants sought
Research Site — Columbia, South Carolina (7.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06677060)

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

Moderate to Severe Chronic Obstructive Pulmonary Disease Phase 2, Phase 3 Interventional 1,156 participants sought
Bogan Sleep Consultants, LLC — Columbia, South Carolina (7.9 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07363694)

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Anaplastic Kidney Wilms Tumor, Recurrent Kidney Wilms Tumor Phase 2 Interventional 256 participants sought
Prisma Health Richland Hospital — Columbia, South Carolina (7.9 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT04322318)

Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

Sleep Wake Disorders, Sleep Disorders, Circadian Rhythm Phase 3 Interventional 70 participants sought
Vanda Investigational Site — Columbia, South Carolina (7.9 mi) · Sponsor: Vanda Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT04652882)

A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

Uterine Fibroids, Endometriosis Phase 3 Interventional 1,000 participants sought
West Columbia — West Columbia, South Carolina (10.2 mi) · Sponsor: Sumitomo Pharma Switzerland GmbH
See eligibility & contact on ClinicalTrials.gov (NCT05862272)

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

NonSegmental Vitiligo Phase 3 Interventional 180 participants sought
Columbia Dermatology — Columbia, South Carolina (7.9 mi) · Sponsor: Incyte Corporation
See eligibility & contact on ClinicalTrials.gov (NCT06548360)

Mindful Walking Neural Correlates of Executive Function in SC Older Adults at Risk of Dementias

Older Adults With Elevated Dementia Risk Phase 2 Interventional 54 participants sought
University of South Carolina — Columbia, South Carolina (7.9 mi) · Sponsor: University of South Carolina
See eligibility & contact on ClinicalTrials.gov (NCT07638046)

A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

Idiopathic Short Stature Phase 2 Interventional 100 participants sought
Prisma Health Children's Hospital - Midlands — Columbia, South Carolina (7.9 mi) · Sponsor: BioMarin Pharmaceutical
See eligibility & contact on ClinicalTrials.gov (NCT06382155)

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis Phase 3 Interventional 762 participants sought
89bio Clinical Study Site — Columbia, South Carolina (7.9 mi) · Sponsor: 89bio, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06419374)

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

Lower Extremity Acute Limb Ischemia, LE ALI N/A Observational 300 participants sought
Lexington Medical Center — West Columbia, South Carolina (10.2 mi) · Sponsor: Penumbra Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06747117)

A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.

Hidradenitis Suppurativa Phase 2 Interventional 240 participants sought
Columbia Dermatology & Aesthetics — Columbia, South Carolina (7.9 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07228390)

Beneficial or Fostering Future Struggles (B.F.F.s)? Characterizing the Role of Friends in the Development of 13- to 17-Year-Old Adolescents

Child Maltreatment, Interpersonal Relations N/A Interventional 120 participants sought
University of South Carolina — Columbia, South Carolina (7.9 mi) · Sponsor: University of South Carolina
See eligibility & contact on ClinicalTrials.gov (NCT05893459)

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Advanced Breast Cancer Phase 3 Interventional 788 participants sought
Research Site — West Columbia, South Carolina (10.2 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06380751)

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Arrhythmia, Bradycardia N/A Observational 20,000 participants sought
Research site — Columbia, South Carolina (7.9 mi) · Sponsor: Medtronic
See eligibility & contact on ClinicalTrials.gov (NCT00271180)

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

B Acute Lymphoblastic Leukemia Associated With Down Syndrome, Down Syndrome N/A Observational 330 participants sought
Prisma Health Richland Hospital — Columbia, South Carolina (7.9 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT05702645)

A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 2

Narcolepsy Type 2 Phase 3 Interventional 176 participants sought
Alkermes Investigational Site — Columbia, South Carolina (7.9 mi) · Sponsor: Alkermes, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07502443)
Actively enrolling

Studies you may be able to join near Columbia

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Columbia

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Velocity Clinical Research

★ 4.0
1655 Bernardin Ave Ste 300, Columbia, SC 29204
(803) 766-2680
"Be sure to get a copy of your contract for study with payment details and a contact number for any medical complications."
— Azilee Billy, 3★

MUSC Research Center - Columbia

2001 Laurel St, Columbia, SC 29204
(803) 255-2927

Biocentric Health Research Center

★ 4.1
160 Medical Cir, West Columbia, SC 29169
(803) 764-2406
"It has been a great experience to work with this company's excellent team. They are very friendly, provide excellent service, and accommodate appoint…"
— Laura C. Bonilla, 5★

Vista Clinical Research

★ 5.0
700 Gervais St Ste 300, Columbia, SC 29201
(803) 251-1160
"ANY CALL BACK NUMBERS>>? Sleep to Heart rate and blood testing sugar testing have eating pyramids .<br>Would like to be paid for Clinical Research"
— jessie parsley, 5★

Carolina Clinical Research Services

712 Richland St # H, Columbia, SC 29201
(803) 988-0080

Columbia Digestive Health Research

2739 Laurel St Ste 2-A, Columbia, SC 29204
(803) 386-8933

South Carolina Clinical Research

1301 Taylor St #5L, Columbia, SC 29201
(803) 988-1438

USC COBRE Center for Targeted Therapeutics (CTT)

Coker Life Sciences Building, 700 Sumter St, Columbia, SC 29208
(803) 777-4689

Lexington Medical Center Park 3

★ 5.0
222 E Medical Ln, West Columbia, SC 29169
"Excellent hospital with great quality doctor and nursing care. The staff is always so very helpful and the facility is very clean."
— Denise Perez, 5★

Clinical trials in Columbia: what's recruiting

The Columbia area currently has 190 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Columbia, the most active research areas are:

  • Cancer & Oncology7 studies
  • Heart & Vascular3 studies
  • Liver & Kidney2 studies
  • Lungs & Breathing1 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Columbia, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Columbia

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Columbia participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Columbia?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Columbia safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Columbia, SC?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Columbia typically complete one or two studies per year.

Paid clinical trials near Columbia

Other metros within reach

Rock Hill, SC603 Charlotte, NC666 Gastonia, NC661 Augusta, GA185 Spartanburg, SC364 Concord, NC645 Charleston, SC737 Mauldin, SC378

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Columbia Severe Chronic Pruritus in Columbia Chronic Kidney Disease (HealthMatch) in Columbia Bladder Issues Due To Spinal Cord Injury in Columbia All conditions

More of SC

Charleston737 Rock Hill603 Greenville380 Mauldin378 Spartanburg364 Myrtle Beach92

New paid studies open every week

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