Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/SC/Charleston
Updated October 2026 from ClinicalTrials.gov

Paid Clinical Trials in Charleston, SC

Studies commonly pay $75 to $4,500 per completed study

737 clinical trials are currently recruiting participants within 30 miles of Charleston. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

737studies recruiting
2+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Charleston right now

Top 25 of 737 recruiting studies, sorted by proximity — each links to its official registry page

Quantitative Cardiac Parametric Mapping

Cardiomyopathy, Myocarditis, Ischemic Heart Disease N/A Interventional 240 participants sought
Medical University of South Carolina — Charleston, South Carolina (3.5 mi) · Sponsor: Medical University of South Carolina
See eligibility & contact on ClinicalTrials.gov (NCT02855554)

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications Phase 3 Interventional 115 participants sought
Medical University of South Carolina (Adults and Pediatrics) — Charleston, South Carolina (3.5 mi) · Sponsor: Pierre Fabre Medicament
See eligibility & contact on ClinicalTrials.gov (NCT03394365)

CARS: Cannabis and Alcohol Reduction Study

Cannabis Use, Alcohol Use, Unspecified N/A Interventional 52 participants sought
Medical University of South Carolina — Charleston, South Carolina (3.5 mi) · Sponsor: Medical University of South Carolina
See eligibility & contact on ClinicalTrials.gov (NCT05486234)

Safety and Efficacy of Mesenchymal Stem Cells Associated With Chronic Pancreatitis Pain

Chronic Pancreatitis, Chronic Pain EARLY/Phase 1 Interventional 48 participants sought
Medical University of South Carolina — Charleston, South Carolina (3.5 mi) · Sponsor: Medical University of South Carolina
See eligibility & contact on ClinicalTrials.gov (NCT06205342)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
Medical University of South Carolina ( Site 0153) — Charleston, South Carolina (3.5 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Charleston, South Carolina (3.5 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis With Cardiomyopathy Phase 3 Interventional 1,750 participants sought
Clinical Trial Site — Charleston, South Carolina (3.5 mi) · Sponsor: Alnylam Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07052903)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Ralph H Johnson VA Medical Center — Charleston, South Carolina (3.5 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)

Alpha 1-Antitrypsin Deficiency Phase 1, Phase 2 Interventional 106 participants sought
Clinical Study Center — Charleston, South Carolina (3.5 mi) · Sponsor: Beam Therapeutics Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06389877)

Optimizing Care for Cancer Survivors With Depression: Project 3

Cancer, Depression N/A Interventional 45 participants sought
Medical University of South Carolina — Charleston, South Carolina (3.5 mi) · Sponsor: Medical University of South Carolina
See eligibility & contact on ClinicalTrials.gov (NCT06930729)

WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis Phase 2 Interventional 164 participants sought
WISPer Site in Charleston, SC — Charleston, South Carolina (3.5 mi) · Sponsor: Mediar Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT06967805)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Charleston, South Carolina (3.5 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

Real Life Evaluation of the LibAirty Airway Clearance System in Adults With Bronchiectasis (RELACS)

Bronchiectasis Adult N/A Observational 200 participants sought
Medical University of South Carolina — Charleston, South Carolina (3.5 mi) · Sponsor: Synchrony-Medical, Ltd
See eligibility & contact on ClinicalTrials.gov (NCT07135284)

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

HNSCC, ESCC Phase 1 Interventional 150 participants sought
Normunity Investigational Site — Charleston, South Carolina (3.5 mi) · Sponsor: Normunity AccelCo, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07182149)

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric) Phase 3 Interventional 117 participants sought
MUSC Shawn Jenkins Children's Hospital - Cardiology — North Charleston, South Carolina (2.6 mi) · Sponsor: Bayer
See eligibility & contact on ClinicalTrials.gov (NCT07192952)

Closed-loop rTMS-EEG During Visuomotor Integration.

Visuomotor Skills, Brain Lesion (General) N/A Interventional 20 participants sought
Medical University of South Carolina — Charleston, South Carolina (3.5 mi) · Sponsor: Medical University of South Carolina
See eligibility & contact on ClinicalTrials.gov (NCT07249801)

A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

Myelodysplastic Syndrome, Acute Myeloid Leukemia Phase 1 Interventional 178 participants sought
Hollings Cancer Center — Charleston, South Carolina (3.5 mi) · Sponsor: Seagen, a wholly owned subsidiary of Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT04227847)

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer, c-MET Phase 3 Interventional 768 participants sought
Medical University of South Carolina /ID# 251383 — Charleston, South Carolina (3.5 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT04928846)

Evaluation of Trauma Center-Based Intervention for Adolescent Traumatic Injury Survivors

Traumatic Injury, Technology N/A Interventional 300 participants sought
Medical University of South Carolina — Charleston, South Carolina (3.5 mi) · Sponsor: Medical University of South Carolina
See eligibility & contact on ClinicalTrials.gov (NCT05086757)

Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease

Arterial Disease of Legs, Below-the-knee Obstruction N/A Interventional 368 participants sought
Medical University of South Carolina(MUSC) Health Ashley River Tower — Charleston, South Carolina (3.5 mi) · Sponsor: Concept Medical Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06182397)

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

Colitis, Ulcerative N/A Observational 300 participants sought
Medical University of South Carolina (MUSC) — Charleston, South Carolina (3.5 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT06398626)
Actively enrolling

Studies you may be able to join near Charleston

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Charleston

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Clinical Research Center Of The Carolinas

1364 Ashley River Rd, Charleston, SC 29407
(843) 375-8111

Coastal Carolina Research Center

★ 4.4
4920 O'Hear Ave Ste 101, North Charleston, SC 29405
(843) 856-3784
"I feel Coastal Carolina is a valuable asset to the research community in the Charleston area. They are extremely welcoming and professional. Their ex…"
— Pam, 5★

Clinical trials in Charleston: what's recruiting

The Charleston area currently has 737 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Charleston, the most active research areas are:

  • Cancer & Oncology10 studies
  • Heart & Vascular4 studies
  • Brain & Mental Health2 studies
  • Lungs & Breathing1 studies
  • Immune & Skin1 studies

Every listing shows the study phase, the recruiting site and its distance from Charleston, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Charleston

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Charleston participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in Charleston safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Charleston, SC?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Charleston?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Charleston typically complete one or two studies per year.

Paid clinical trials near Charleston

Other metros within reach

Myrtle Beach, SC92 Savannah, GA176 Columbia, SC190 Augusta, GA185 Rock Hill, SC603 Fayetteville, NC125 Wilmington, NC115 Charlotte, NC666

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Charleston Bladder Issues Due To Spinal Cord Injury in Charleston All conditions

More of SC

Rock Hill603 Greenville380 Mauldin378 Spartanburg364 Columbia190 Myrtle Beach92

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