Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NC/Wilmington
Updated November 2026 from ClinicalTrials.gov

Paid Clinical Trials in Wilmington, NC

Studies commonly pay $75 to $4,500 per completed study

120 clinical trials are currently recruiting participants within 30 miles of Wilmington. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

120studies recruiting
9+research centers nearby
7condition categories
Live from the NIH registry

Studies recruiting near Wilmington right now

Top 25 of 120 recruiting studies, sorted by proximity — each links to its official registry page

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

Brain Tumor, Recurrent, Brain Tumor N/A Observational 600 participants sought
Atlantic Brain & Spine — Wilmington, North Carolina (3.8 mi) · Sponsor: GT Medical Technologies, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04427384)

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate Phase 2 Interventional 1,431 participants sought
Wilmington Health, PLLC — Wilmington, North Carolina (3.8 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07415044)

A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

HIV Infections Phase 2 Interventional 186 participants sought
GSK Investigational Site — Wilmington, North Carolina (3.8 mi) · Sponsor: ViiV Healthcare
See eligibility & contact on ClinicalTrials.gov (NCT07202546)

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Heart Failure Phase 3 Interventional 4,200 participants sought
Wilmington Health — Wilmington, North Carolina (3.8 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT06935370)

A Study Assessing Safety, Tolerability, and Efficacy of INNA-051 in Preventing Respiratory Illness Due to Viral Infections in Healthy Adults 18 to 45 Years of Age

Viral Respiratory Infection, Viral Respiratory Illnesses Phase 2 Interventional 1,100 participants sought
Accellacare - Wilmington — Wilmington, North Carolina (3.8 mi) · Sponsor: ENA Respiratory Pty Ltd
See eligibility & contact on ClinicalTrials.gov (NCT07222670)

Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)

Schizophrenia N/A Observational 1,500 participants sought
PPD Virtual - PPD - US — Wilmington, North Carolina (3.8 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT07379827)

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

Obesity, Overweight Phase 2 Interventional 360 participants sought
Accellacare - Tradd Court - Wilmington /ID# 282200 — Wilmington, North Carolina (3.8 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT07752979)

Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

Arthritis, Psoriatic Phase 3 Interventional 600 participants sought
Clinical Site — Leland, North Carolina (9.6 mi) · Sponsor: MoonLake Immunotherapeutics AG
See eligibility & contact on ClinicalTrials.gov (NCT06641089)

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

Obesity Phase 3 Interventional 1,150 participants sought
Accellacare and KDCILM, LLC — Wilmington, North Carolina (3.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07339423)

A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout

Uncontrolled Gout Phase 3 Interventional 270 participants sought
Cape Fear Arthritis Care, PLLC — Leland, North Carolina (9.6 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07388498)

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

Atrial Fibrillation (AF) Phase 3 Interventional 2,500 participants sought
Anthos Investigative Site 9952 — Wilmington, North Carolina (3.8 mi) · Sponsor: Anthos Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05712200)

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

Intracerebral Hemorrhage, Atrial Fibrillation Phase 3 Interventional 700 participants sought
New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: Yale University
See eligibility & contact on ClinicalTrials.gov (NCT03907046)

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Endometrial Carcinoma, Endometrial Clear Cell Adenocarcinoma Phase 3 Interventional 360 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05256225)

A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.

Chronic Kidney Disease Phase 3 Interventional 7,000 participants sought
Research Site — Wilmington, North Carolina (3.8 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07753993)

A Global, Multicenter Study to Assess Maternal, Fetal and Infant Outcomes of Exposure to Palynziq® (Pegvaliase) During Pregnancy and Breastfeeding

Phenylketonuria, Maternal N/A Observational 50 participants sought
Syneos Health — Wilmington, North Carolina (3.8 mi) · Sponsor: BioMarin Pharmaceutical
See eligibility & contact on ClinicalTrials.gov (NCT05579548)

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

Acne Phase 1, Phase 2 Interventional 800 participants sought
Trial Management Associates - Wilmington - Floral Parkway- Site Number : 8400104 — Wilmington, North Carolina (3.8 mi) · Sponsor: Sanofi Pasteur, a Sanofi Company
See eligibility & contact on ClinicalTrials.gov (NCT06316297)

MOVE: Tenosynovial Giant Cell Tumor (TGCT) Real-World Participant Experience With Vimseltinib

Tenosynovial Giant Cell Tumor N/A Observational 100 participants sought
Synexus Clinical Research, US INC — Wilmington, North Carolina (3.8 mi) · Sponsor: Deciphera Pharmaceuticals, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07075471)

A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight

Obesity, Type 2 Diabetes Phase 3 Interventional 2,500 participants sought
Accellacare Wilmington — Wilmington, North Carolina (3.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07564414)

A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults

Pneumococcal Disease Phase 3 Interventional 4,670 participants sought
Accellacare - Wilmington — Wilmington, North Carolina (3.8 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07794748)
Actively enrolling

Studies you may be able to join near Wilmington

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Wilmington

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Accellacare Research of Wilmington

★ 4.9
1907 Tradd Ct, Wilmington, NC 28401
(910) 799-5500
"My experience with PMG Research of Wilmington has been just great.<br>the staff there are always very friendly and very professional. they always mak…"
— Cynthia Williamson, 5★

PMG Research of Wilmington

★ 4.0
1202 Medical Center Dr, Wilmington, NC 28401
(910) 815-6108

M3 Wake Research Wilmington

2716 Ashton Dr, Wilmington, NC 28412
(910) 408-5746

Catalyst Clinical Research

2528 Independence Blvd Ste 100, Wilmington, NC 28412
(919) 648-0668

WDC Clinical Research Center

710 Military Cutoff Rd Ste 220, Wilmington, NC 28405
(910) 726-9346

PharPoint Research, Inc.

★ 5.0
21 S Front St Ste 200, Wilmington, NC 28401
(910) 790-0482
"Very good! I'm happy to see such wonderful Souls diving deep into helping Humanity."
— MindOps, 5★

Novant Health New Hanover Regional Medical Center

★ 3.1
2131 S 17th St, Wilmington, NC 28401
(910) 667-7000
"Nurses took great care of me and honored all my requests. And the surgery must have gone well, because I came out great!"
— david kirk, 5★

Coastal Horizons Center

★ 2.8 (89 reviews)
615 Shipyard Blvd, Wilmington, NC 28412
(910) 343-0145
"Switched here from Better Life Partners, which was an awesome program. This place sucks. I've been in the lobby for 3 1/2 hours waiting to be called,…"
— Joshua Ward, 1★

Eastcoast Research

★ 5.0
1213 Culbreth Dr Ste 208, Wilmington, NC 28405
(910) 763-3260
"Did a one on one discussion with a narrator. She was very professional and polite. It was very easy and a good experience."
— Barbara Baize, 5★

Clinical trials in Wilmington: what's recruiting

The Wilmington area currently has 120 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Wilmington, the most active research areas are:

  • Cancer & Oncology3 studies
  • Immune & Skin3 studies
  • Diabetes & Metabolism3 studies
  • Heart & Vascular1 studies
  • Lungs & Breathing1 studies

Every listing shows the study phase, the recruiting site and its distance from Wilmington, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Wilmington

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Wilmington participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Wilmington pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Wilmington safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Wilmington, NC?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
How often do new paid studies open in Wilmington?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Wilmington.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Wilmington typically complete one or two studies per year.

Paid clinical trials near Wilmington

Other metros within reach

Myrtle Beach, SC94 Fayetteville, NC124 Raleigh, NC1,687 Cary, NC1,696 Durham, NC1,696 Burlington, NC747 Charleston, SC741 Greensboro, NC597

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Wilmington Chronic Kidney Disease (HealthMatch) in Wilmington Bladder Issues Due To Spinal Cord Injury in Wilmington All conditions

More of NC

Durham1,696 Cary1,696 Raleigh1,687 Burlington747 Charlotte673 Gastonia667 Concord648 Winston-Salem599 High Point598 Greensboro597 Asheville125 Fayetteville124

New paid studies open every week

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