Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NC/Wilmington
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Wilmington, NC

Studies commonly pay $75 to $4,500 per completed study

109 clinical trials are currently recruiting participants within 30 miles of Wilmington. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

109studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Wilmington right now

Top 25 of 109 recruiting studies, sorted by proximity — each links to its official registry page

Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease N/A Observational 3,000 participants sought
PMG Research — Wilmington, North Carolina (3.8 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT01915511)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

Obesity, Knee Osteoarthritis (OA) Phase 3 Interventional 400 participants sought
Accellacare and KDCILM, LLC — Wilmington, North Carolina (3.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07481630)

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

Locally Advanced Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8 Phase 3 Interventional 474 participants sought
Novant Health Cancer Institute Radiation Oncology - Wilmington — Wilmington, North Carolina (3.8 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05624996)

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction Phase 3 Interventional 5,056 participants sought
Accellacare of Wilmington — Wilmington, North Carolina (3.8 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037459)

A Global, Multicenter Study to Assess Maternal, Fetal and Infant Outcomes of Exposure to Palynziq® (Pegvaliase) During Pregnancy and Breastfeeding

Phenylketonuria, Maternal N/A Observational 50 participants sought
Syneos Health — Wilmington, North Carolina (3.8 mi) · Sponsor: BioMarin Pharmaceutical
See eligibility & contact on ClinicalTrials.gov (NCT05579548)

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate Phase 2 Interventional 1,431 participants sought
Wilmington Health, PLLC — Wilmington, North Carolina (3.8 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07415044)

AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

Obesity Phase 3 Interventional 600 participants sought
PMG Research of Wilmington LLC — Wilmington, North Carolina (3.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07503210)

A Study to Assess the Safety and Effectiveness of ELAPR002f Injectable Gel in Adult Participants With Atrophic Acne Scars

Acne Scars Phase 3 Interventional 395 participants sought
Wilmington Dermatology Center /ID# 256192 — Wilmington, North Carolina (3.8 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT07207369)

Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)

Schizophrenia N/A Observational 1,500 participants sought
PPD Virtual - PPD - US — Wilmington, North Carolina (3.8 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT07379827)

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

Miscellaneous Neoplasm, Nos, Non-Neoplastic Condition, Nos N/A Interventional 535 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT07091617)

A Study Evaluating the Effect of BRIUMVI® (Ublituximab) on Pregnancy and Infant Outcomes in Participants With Multiple Sclerosis (MS)

Multiple Sclerosis N/A Observational 728 participants sought
BRIUMVI® Pregnancy Registry Virtual Research Coordination Center — Wilmington, North Carolina (3.8 mi) · Sponsor: TG Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06433765)

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Obesity, Heart Failure Phase 3 Interventional 5,610 participants sought
Accellacare Wilmington — Wilmington, North Carolina (3.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07567001)

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

Obesity or Overweight Phase 3 Interventional 300 participants sought
Accellacare Research of Wilmington — Wilmington, North Carolina (3.8 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07575399)

A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee

Osteoarthritis (OA) of the Knee Phase 2 Interventional 135 participants sought
M3 Wake Research - Wilmington, NC — Wilmington, North Carolina (3.8 mi) · Sponsor: Pacira Pharmaceuticals, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06884865)

Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring

Pregnancy Related, Pregnancy Complications N/A Observational 728 participants sought
PPD — Wilmington, North Carolina (3.8 mi) · Sponsor: Sumitomo Pharma Switzerland GmbH
See eligibility & contact on ClinicalTrials.gov (NCT05739123)

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 Phase 3 Interventional 1,524 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06876714)

A Study Evaluating the Presence and Concentration of BRIUMVI™ (Ublituximab) in Breast Milk

Relapsing Multiple Sclerosis N/A Observational 16 participants sought
PROVIDE Virtual Research Coordination Center — Wilmington, North Carolina (3.8 mi) · Sponsor: TG Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06143514)

A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

Crohn Disease Phase 2 Interventional 60 participants sought
Innovo Research - Wilmington Gastroenterology Associates — Wilmington, North Carolina (3.8 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07483099)

A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)

Active Rheumatoid Arthritis Phase 2 Interventional 180 participants sought
Carolina Arthritis Associates - Cliniverse Research (Network) — Wilmington, North Carolina (3.8 mi) · Sponsor: Elevara Medicines Limited
See eligibility & contact on ClinicalTrials.gov (NCT07409103)

A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity

Obesity Phase 2 Interventional 230 participants sought
KDCILM, LLC & Accellacare US, Inc. — Wilmington, North Carolina (3.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07639021)

A Study to Test Whether BI 3034701 Helps People to Lose Weight Who Live With Obesity or Overweight

Obesity, Overweight Phase 2 Interventional 300 participants sought
Accellacare-Wilmington-67123 — Wilmington, North Carolina (3.8 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07662122)
Actively enrolling

Studies you may be able to join near Wilmington

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Wilmington

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Accellacare Research of Wilmington

★ 4.9
1907 Tradd Ct, Wilmington, NC 28401
(910) 799-5500
"My experience with PMG Research of Wilmington has been just great.<br>the staff there are always very friendly and very professional. they always mak…"
— Cynthia Williamson, 5★

PMG Research of Wilmington

★ 4.0
1202 Medical Center Dr, Wilmington, NC 28401
(910) 815-6108

M3 Wake Research Wilmington

2716 Ashton Dr, Wilmington, NC 28412
(910) 408-5746

Catalyst Clinical Research

2528 Independence Blvd Ste 100, Wilmington, NC 28412
(919) 648-0668

WDC Clinical Research Center

710 Military Cutoff Rd Ste 220, Wilmington, NC 28405
(910) 726-9346

PharPoint Research, Inc.

★ 5.0
21 S Front St Ste 200, Wilmington, NC 28401
(910) 790-0482
"Very good! I'm happy to see such wonderful Souls diving deep into helping Humanity."
— MindOps, 5★

Novant Health New Hanover Regional Medical Center

★ 3.1
2131 S 17th St, Wilmington, NC 28401
(910) 667-7000
"Nurses took great care of me and honored all my requests. And the surgery must have gone well, because I came out great!"
— david kirk, 5★

Coastal Horizons Center

★ 2.8 (89 reviews)
615 Shipyard Blvd, Wilmington, NC 28412
(910) 343-0145
"Switched here from Better Life Partners, which was an awesome program. This place sucks. I've been in the lobby for 3 1/2 hours waiting to be called,…"
— Joshua Ward, 1★

Eastcoast Research

★ 5.0
1213 Culbreth Dr Ste 208, Wilmington, NC 28405
(910) 763-3260
"Did a one on one discussion with a narrator. She was very professional and polite. It was very easy and a good experience."
— Barbara Baize, 5★

Clinical trials in Wilmington: what's recruiting

The Wilmington area currently has 109 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Wilmington, the most active research areas are:

  • Diabetes & Metabolism7 studies
  • Immune & Skin5 studies
  • Cancer & Oncology4 studies
  • Heart & Vascular3 studies
  • Lungs & Breathing1 studies

Every listing shows the study phase, the recruiting site and its distance from Wilmington, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Wilmington

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Wilmington participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Wilmington pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Wilmington safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Wilmington, NC?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
How often do new paid studies open in Wilmington?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Wilmington.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Wilmington typically complete one or two studies per year.

Paid clinical trials near Wilmington

Other metros within reach

Myrtle Beach, SC89 Fayetteville, NC119 Raleigh, NC1,671 Cary, NC1,679 Durham, NC1,679 Burlington, NC759 Charleston, SC733 Greensboro, NC596

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Wilmington Chronic Kidney Disease (HealthMatch) in Wilmington Bladder Issues Due To Spinal Cord Injury in Wilmington All conditions

More of NC

Durham1,679 Cary1,679 Raleigh1,671 Burlington759 Gastonia651 Charlotte648 Concord627 High Point597 Winston-Salem597 Greensboro596 Asheville120 Fayetteville119

New paid studies open every week

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