Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NC/Burlington
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Burlington, NC

Studies commonly pay $75 to $4,500 per completed study

748 clinical trials are currently recruiting participants within 30 miles of Burlington. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

748studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Burlington right now

Top 25 of 748 recruiting studies, sorted by proximity — each links to its official registry page

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Cone Health Cancer Center at Alamance Regional — Burlington, North Carolina (2.2 mi) · Sponsor: SWOG Cancer Research Network

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
UNC Lineberger Comprehensive Cancer Center — Chapel Hill, North Carolina (25.7 mi) · Sponsor: National Cancer Institute (NCI)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
University of North Carolina Medical Center ( Site 0136) — Chapel Hill, North Carolina (25.7 mi) · Sponsor: Merck Sharp & Dohme LLC

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

Urothelial Cancer, Bladder Cancer Phase 2, Phase 3 Interventional 630 participants sought
Research Site — Chapel Hill, North Carolina (25.7 mi) · Sponsor: Daiichi Sankyo

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma, Relapsed/Refractory Multiple Myeloma Phase 2 Interventional 100 participants sought
UNC Hospitals Adult Oncology Clinics — Chapel Hill, North Carolina (25.7 mi) · Sponsor: C4 Therapeutics, Inc.

Registry for Adults With Plasma Cell Disorders (PCD's)

Multiple Myeloma, Amyloidosis N/A Observational 2,000 participants sought
North Carolina Cancer Hospital — Chapel Hill, North Carolina (25.7 mi) · Sponsor: UNC Lineberger Comprehensive Cancer Center

Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI

Endometriosis Phase 2 Interventional 24 participants sought
University of North Carolina at Chapel Hill — Chapel Hill, North Carolina (25.7 mi) · Sponsor: University of North Carolina, Chapel Hill

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Chronic Migraine Phase 3 Interventional 420 participants sought
Headache Wellness Center /ID# 270568 — Greensboro, North Carolina (18.1 mi) · Sponsor: AbbVie

Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy

Breast Cancer, Quality of Life Phase 2 Interventional 90 participants sought
University of North Carolina — Chapel Hill, North Carolina (25.7 mi) · Sponsor: UNC Lineberger Comprehensive Cancer Center

Feasibility Test of Action Planning in Pediatric IBD

Inflammatory Bowel Diseases N/A Interventional 60 participants sought
University of North Carolina-Chapel Hill School of Medicine — Chapel Hill, North Carolina (25.7 mi) · Sponsor: University of North Carolina, Chapel Hill

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

Colitis, Ulcerative N/A Observational 300 participants sought
University of North Carolina at Chapel Hill, Division of Gastroenterology and Hepatology — Chapel Hill, North Carolina (25.7 mi) · Sponsor: Pfizer

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
University of North Carolina-Hillsborough Campus — Hillsborough, North Carolina (20.6 mi) · Sponsor: ECOG-ACRIN Cancer Research Group

The Safety and Tolerability of LBS-007 in Patients With Relapsed or Resistant Acute Leukaemias

Relapsed or Resistant Acute Leukaemias Phase 1, Phase 2 Interventional 90 participants sought
UNC Hospitals, The University of North Carolina at Chapel Hill — Chapel Hill, North Carolina (25.7 mi) · Sponsor: Lin BioScience, Inc

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

Squamous Cell Carcinoma of Head and Neck Phase 1, Phase 2 Interventional 287 participants sought
University of North Carolina at Chapel Hill — Chapel Hill, North Carolina (25.7 mi) · Sponsor: Janssen Research & Development, LLC

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

Acute Myeloid Leukemia (AML) Phase 3 Interventional 1,300 participants sought
University of North Carolina, Chapel Hill — Chapel Hill, North Carolina (25.7 mi) · Sponsor: Kura Oncology, Inc.

Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease N/A Observational 3,000 participants sought
Pulmonix LLC — Greensboro, North Carolina (18.1 mi) · Sponsor: Duke University

Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness

Hearing Loss, Unilateral, Deafness, Unilateral N/A Interventional 60 participants sought
University of North Carolina — Chapel Hill, North Carolina (25.7 mi) · Sponsor: Cochlear

A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

Acute HIV Infection Phase 2 Interventional 48 participants sought
3203, Greensboro CRS — Greensboro, North Carolina (18.1 mi) · Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis

Lewy Body Dementia Psychosis Phase 2 Interventional 180 participants sought
UNC Hospitals — Chapel Hill, North Carolina (25.7 mi) · Sponsor: ACADIA Pharmaceuticals Inc.

Mitigating PTSD-CUD After Sexual Assault

Posttraumatic Stress Disorder, Cannabis Use Disorder Phase 1, Phase 2 Interventional 68 participants sought
UNC Chapel Hill — Chapel Hill, North Carolina (25.7 mi) · Sponsor: University of Nevada, Las Vegas
Actively enrolling

Studies you may be able to join near Burlington

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Research study for heart failure

This study is enrolling adults in eligible areas of the United States who have been diagnosed with heart failure. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Google-rated

Top-rated research centers in Burlington

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Cone Health Cancer Center at Alamance Regional

★ 4.7 (35 reviews)
1236 Huffman Mill Rd #120, Burlington, NC 27215
(336) 538-7725
"Outstanding facility and awesome staff!"
— Willie Walker, 5★

Duke Clinical Research Institute

★ 4.9
300 W Morgan St, Durham, NC 27701
(919) 668-8700
"Great awesome place to work!! Loved it❤"
— Ramona Williams, 5★

UNC CTRC (Clinical & Translational Research Center)

★ 5.0
Burnett-Womack Building, 160 Dental Cir, Chapel Hill, NC 27514
(919) 966-1437

North Carolina Clinical Research

★ 5.0
2615 Lake Dr #301, Raleigh, NC 27607
(919) 881-0309
"I donated my brain here. I think..."
— Scott B, 5★

Triad Clinical Trials

★ 5.0
811 Dolley Madison Rd, Greensboro, NC 27410
(336) 235-0991
"Staff is very friendly.They make sure you understand everything with the study"
— Kenyatta Spruill, 5★

Clinical Trials of North Carolina

★ 2.5
811 9th St, Durham, NC 27705
(919) 590-9024
"This is NOT A Clinical trials it is a Dentistry and the phone number on the page do not Work"
— Blue Wallpaper, 1★

University of North Carolina Community Research Center & Clinic

★ 4.5
University of North Carolina Community Research Center & Clinic, 212 Finley Golf Course Rd, Chapel Hill, NC 27517
"Great place for youth, families, couples, and adults to receive evidence-based clinical assessment, therapy, and support from mental health professio…"
— Emma Choplin, 5★

UNC Clinical Research Alliance

123 W Franklin St #530, Chapel Hill, NC 27516
(919) 966-2340

Velocity Clinical Research

★ 4.5
300 E Main St Ste 200, Durham, NC 27701
(919) 503-4711
"Dr Cromwell and the entire staff are professional and caring people who made me feel important and valued during this year long trial.<br>I recommend…"
— Bob Kingsbery, 5★

Clinical trials in Burlington: what's recruiting

The Burlington area currently has 748 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Burlington, the most active research areas are:

  • Cancer & Oncology13 studies
  • Immune & Skin2 studies
  • Liver & Kidney1 studies
  • Brain & Mental Health1 studies
  • Lungs & Breathing1 studies

Every listing shows the study phase, the recruiting site and its distance from Burlington, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Burlington

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Burlington participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Burlington pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Burlington safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Burlington, NC?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
How often do new paid studies open in Burlington?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Burlington.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Burlington typically complete one or two studies per year.

Paid clinical trials near Burlington

Other metros within reach

By condition

Eligibility and exclusions, condition by condition

More of NC

New paid studies open every week

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