Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/VA/Roanoke
Updated October 2026 from ClinicalTrials.gov

Paid Clinical Trials in Roanoke, VA

Studies commonly pay $75 to $4,500 per completed study

192 clinical trials are currently recruiting participants within 30 miles of Roanoke. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

192studies recruiting
4+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Roanoke right now

Top 25 of 192 recruiting studies, sorted by proximity — each links to its official registry page

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

Heart Failure, Acute Heart Failure Phase 3 Interventional 5,200 participants sought
Salem, VA Investigative Site 10048 — Salem, Virginia (5.4 mi) · Sponsor: Colorado Prevention Center
See eligibility & contact on ClinicalTrials.gov (NCT06008197)

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Phase 2 Interventional 120 participants sought
BRCC/Oncology & Hematology Associates of SW Virginia — Blacksburg, Virginia (25.3 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06465329)

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

Limited Stage Small Cell Lung Cancer Phase 2 Interventional 250 participants sought
Blue Ridge Cancer Center (Oncology & Hematology Associates of Southwest VA) — Salem, Virginia (5.4 mi) · Sponsor: SCRI Development Innovations, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06773910)

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Heart Failure Phase 3 Interventional 4,200 participants sought
Carilion Clinic — Roanoke, Virginia (1.1 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT06935370)

A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk

Atherosclerosis, Cardiovascular Diseases Phase 3 Interventional 252 participants sought
Carilion Clinic — Roanoke, Virginia (1.1 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07613294)

Inflammation and Medical Provider Attitudes, Cognition, and Treatment Decisions Study

Decision-Making, Patient Care Phase 2 Interventional 210 participants sought
Carilion Medical Center — Roanoke, Virginia (1.1 mi) · Sponsor: University of Arkansas, Fayetteville
See eligibility & contact on ClinicalTrials.gov (NCT07842367)

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought
Carilion Roanoke Memorial Hospital — Roanoke, Virginia (1.1 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04251052)

A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer

Diabetic Foot Ulcer, Foot Ulcer Phase 3 Interventional 230 participants sought
Salem Veterans Affairs Medical Center VAMC — Salem, Virginia (5.4 mi) · Sponsor: Energenesis Biomedical Co., Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT05930210)

Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema

Diabetic Retinopathy Phase 2, Phase 3 Interventional 576 participants sought
Vistar Eye Center - Salem /ID# 282879 — Salem, Virginia (5.4 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT07592273)

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Mitral Valve Regurgitation N/A Interventional 1,056 participants sought
Carilion Roanoke Memorial Hospital — Roanoke, Virginia (1.1 mi) · Sponsor: Medtronic Cardiovascular
See eligibility & contact on ClinicalTrials.gov (NCT03242642)

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Cardiovascular Risk, Acute Myocardial Infarction (AMI) Phase 3 Interventional 10,000 participants sought
VA Medical Center_Salem — Salem, Virginia (5.4 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT06118281)

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis Phase 3 Interventional 2,150 participants sought
Akero Clinical Study Site — Roanoke, Virginia (1.1 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06528314)

Real-World Data Collection of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis When Used in Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) to Treat Aortoiliac Occlusive Disease

Aortoiliac Occlusive Disease N/A Observational 158 participants sought
Carilion Clinic — Roanoke, Virginia (1.1 mi) · Sponsor: W.L.Gore & Associates
See eligibility & contact on ClinicalTrials.gov (NCT06872905)

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

Retroperitoneal Sarcoma, Liposarcoma Phase 3 Interventional 250 participants sought
Carilion Roanoke Memorial Hospital — Roanoke, Virginia (1.1 mi) · Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
See eligibility & contact on ClinicalTrials.gov (NCT04031677)

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Low Grade Astrocytoma, Low Grade Glioma Phase 3 Interventional 170 participants sought
Carilion Children's — Roanoke, Virginia (1.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04166409)

A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)

Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 600 participants sought
Site 10 — Blacksburg, Virginia (25.3 mi) · Sponsor: Merus B.V.
See eligibility & contact on ClinicalTrials.gov (NCT06496178)

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

Metastatic Colorectal Cancer Phase 3 Interventional 1,020 participants sought
Blue Ridge Cancer Care - 300202915 — Roanoke, Virginia (1.1 mi) · Sponsor: EMD Serono Research & Development Institute, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07549412)

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

Colorectal Cancer, Pancreatic Ductal Adenocarcinoma Phase 1, Phase 2 Interventional 220 participants sought
Oncology and Hematology Associates of Southwest Virginia (BRCC) ( Site 0295) — Roanoke, Virginia (1.1 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06428409)

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Phase 2, Phase 3 Interventional 690 participants sought
Oncology and Hematology Associates of Southwest Virginia, Inc. - Salem — Salem, Virginia (5.4 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT07221149)

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma Phase 3 Interventional 62 participants sought
Carilion Children's — Roanoke, Virginia (1.1 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT05235165)

eTMS for Veterans and First Responders With PTSD

Post Traumatic Stress Disorder N/A Interventional 20 participants sought
Fralin Biomedical Research Institute — Roanoke, Virginia (1.1 mi) · Sponsor: Virginia Polytechnic Institute and State University
See eligibility & contact on ClinicalTrials.gov (NCT06294106)
Actively enrolling

Studies you may be able to join near Roanoke

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Roanoke

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Fralin Biomedical Research Institute at VTC

★ 4.4
4 Riverside Circle, Roanoke, VA 24016
(540) 526-2500
"Seen promptly and answered questions"
— Julie White, 4★

Carilion Clinic Center for Simulation, Research and Patient Safety

★ 4.9
15 Old Woods Ave, Roanoke, VA 24016
(540) 855-6860
"Attended a pre-joint replacement class here and it was a great experience well worth mine and my wife's time. Excellent presentations, caring and kno…"
— Bill Jennings, 5★

Salem Research Institute Inc

1970 Roanoke Blvd, Salem, VA 24153
(540) 224-1914

Addiction Recovery Research Center

2 Riverside Circle, Roanoke, VA 24016
(540) 315-0205

Clinical trials in Roanoke: what's recruiting

The Roanoke area currently has 192 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Roanoke, the most active research areas are:

  • Cancer & Oncology11 studies
  • Heart & Vascular4 studies
  • Diabetes & Metabolism4 studies
  • Liver & Kidney1 studies

Every listing shows the study phase, the recruiting site and its distance from Roanoke, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Roanoke

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Roanoke participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Roanoke pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Roanoke?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Roanoke safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Roanoke?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.

Paid clinical trials near Roanoke

Other metros within reach

Greensboro, NC586 Winston-Salem, NC588 High Point, NC587 Burlington, NC745 Durham, NC1,695 Cary, NC1,695 Raleigh, NC1,686 Concord, NC640

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Roanoke Bladder Issues Due To Spinal Cord Injury in Roanoke All conditions

More of VA

Arlington2,332 Alexandria2,291 Richmond616 Chesapeake399 Virginia Beach398 Norfolk398 Newport News379 Fredericksburg38

New paid studies open every week

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