Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only

Home/VA/Roanoke

Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Roanoke, VA

Studies commonly pay $75 to $4,500 per completed study

197 clinical trials are currently recruiting participants within 30 miles of Roanoke. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

197studies recruiting

4+research centers nearby

6condition categories

Live from the NIH registry

Studies recruiting near Roanoke right now

Top 25 of 197 recruiting studies, sorted by proximity — each links to its official registry page

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought

Carilion Children's — Roanoke, Virginia (1.1 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Phase 2 Interventional 120 participants sought

BRCC/Oncology & Hematology Associates of SW Virginia — Blacksburg, Virginia (25.3 mi) · Sponsor: Regeneron Pharmaceuticals

See eligibility & contact on ClinicalTrials.gov (NCT06465329)

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Metastatic Castration Sensitive Prostate Cancer (mCSPC), Hormone Sensitive Prostate Cancer Phase 3 Interventional 1,000 participants sought

Blue Ridge Cancer Care — Roanoke, Virginia (1.1 mi) · Sponsor: Pfizer

See eligibility & contact on ClinicalTrials.gov (NCT07028853)

Clinical Trial Evaluating an Amnion Membrane Allograft for Use in the Management of Non- Healing Diabetic Foot Ulcers Versus Standard Of Care

Diabetic Foot Ulcers (DFUs) N/A Interventional 100 participants sought

Professional Education and Research Institute — Roanoke, Virginia (1.1 mi) · Sponsor: Skye Biologics Holdings, LLC

See eligibility & contact on ClinicalTrials.gov (NCT06767501)

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

Limited Stage Small Cell Lung Cancer Phase 2 Interventional 250 participants sought

Blue Ridge Cancer Center (Oncology & Hematology Associates of Southwest VA) — Salem, Virginia (5.4 mi) · Sponsor: SCRI Development Innovations, LLC

See eligibility & contact on ClinicalTrials.gov (NCT06773910)

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 Phase 3 Interventional 1,875 participants sought

Carilion Children's — Roanoke, Virginia (1.1 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT05675410)

Real-World Data Collection of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis When Used in Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) to Treat Aortoiliac Occlusive Disease

Aortoiliac Occlusive Disease N/A Observational 158 participants sought

Carilion Clinic — Roanoke, Virginia (1.1 mi) · Sponsor: W.L.Gore & Associates

See eligibility & contact on ClinicalTrials.gov (NCT06872905)

Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

Urothelial Cancer, Advanced/Metastatic Urothelial Cancer Phase 1, Phase 2 Interventional 132 participants sought

Oncology & Hematology Associates of Southwest Virginia, Inc.,DBA Blue Ridge Cancer Care — Roanoke, Virginia (1.1 mi) · Sponsor: Pfizer

See eligibility & contact on ClinicalTrials.gov (NCT07421700)

A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma Phase 2, Phase 3 Interventional 660 participants sought

Oncology and Hematology Associates of Southwest Virginia /ID# 265834 — Roanoke, Virginia (1.1 mi) · Sponsor: AbbVie

See eligibility & contact on ClinicalTrials.gov (NCT06109272)

PREVAIL Interdisciplinary Track: A Pragmatic Randomized Clinical Trial

Chronic Pain N/A Interventional 150 participants sought

Salem VA Health Care System — Salem, Virginia (5.4 mi) · Sponsor: Salem Veterans Affairs Medical Center

See eligibility & contact on ClinicalTrials.gov (NCT06427356)

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction Phase 3 Interventional 5,056 participants sought

Roanoke Heart Institute PLC — Roanoke, Virginia (1.1 mi) · Sponsor: Amgen

See eligibility & contact on ClinicalTrials.gov (NCT07037459)

The Role of the Locus Coeruleus in Age-related Distractibility

Aging, Alzheimer Disease N/A Interventional 200 participants sought

Virginia Polytechnic Institute and State University — Blacksburg, Virginia (25.3 mi) · Sponsor: Virginia Polytechnic Institute and State University

See eligibility & contact on ClinicalTrials.gov (NCT05574634)

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Cardiovascular Risk, Acute Myocardial Infarction (AMI) Phase 3 Interventional 10,000 participants sought

VA Medical Center_Salem — Salem, Virginia (5.4 mi) · Sponsor: Novo Nordisk A/S

See eligibility & contact on ClinicalTrials.gov (NCT06118281)

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Anaplastic Kidney Wilms Tumor, Recurrent Kidney Wilms Tumor Phase 2 Interventional 256 participants sought

Carilion Children's — Roanoke, Virginia (1.1 mi) · Sponsor: Children's Oncology Group

See eligibility & contact on ClinicalTrials.gov (NCT04322318)

Water Intake and Weight Control in Older Adults

Overweight and Obesity N/A Interventional 375 participants sought

Virginia Tech — Blacksburg, Virginia (25.3 mi) · Sponsor: Virginia Polytechnic Institute and State University

See eligibility & contact on ClinicalTrials.gov (NCT05843318)

Regulating Emotions Like An eXpert Among Adolescents With ADHD

RELAX Telehealth Intervention, Psychoeducational Waitlist Control N/A Interventional 60 participants sought

Child Study Center — Blacksburg, Virginia (25.3 mi) · Sponsor: Virginia Polytechnic Institute and State University

See eligibility & contact on ClinicalTrials.gov (NCT06725186)

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

Non-small Cell Carcinoma, Non-Small Cell Lung Cancer Metastatic Phase 3 Interventional 680 participants sought

Oncology & Hematology Associates of Southwest Virginia Inc dba Blue Ridge Cancer Care — Salem, Virginia (5.4 mi) · Sponsor: Pfizer

See eligibility & contact on ClinicalTrials.gov (NCT07144280)

A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

Lupus Erythematosus, Systemic Phase 3 Interventional 600 participants sought

Carilion Clinic Virginia Tech Carilion School of Medicine — Roanoke, Virginia (1.1 mi) · Sponsor: Janssen Research & Development, LLC

See eligibility & contact on ClinicalTrials.gov (NCT07438496)

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

Ulcerative Colitis, Obesity or Overweight Phase 3 Interventional 350 participants sought

Gastroenterology Consultants of Southwest Virginia — Roanoke, Virginia (1.1 mi) · Sponsor: Eli Lilly and Company

See eligibility & contact on ClinicalTrials.gov (NCT06937086)

NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

Aortic Dissection, Aortic Aneurysm N/A Interventional 110 participants sought

Carilion Clinic — Roanoke, Virginia (1.1 mi) · Sponsor: Endospan Ltd.

See eligibility & contact on ClinicalTrials.gov (NCT04471909)

Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma

Multiple Myeloma Phase 2 Interventional 100 participants sought

Blue Ridge Cancer Center — Roanoke, Virginia (1.1 mi) · Sponsor: SCRI Development Innovations, LLC

See eligibility & contact on ClinicalTrials.gov (NCT05972135)

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

Relapsed or Refractory Multiple Myeloma Phase 3 Interventional 810 participants sought

Local Institution - 0399 — Roanoke, Virginia (1.1 mi) · Sponsor: Celgene

See eligibility & contact on ClinicalTrials.gov (NCT05519085)

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

Relapsing Multiple Sclerosis, Multiple Sclerosis N/A Observational 2,000 participants sought

TG Therapeutics Investigational Trial Site — Salem, Virginia (5.4 mi) · Sponsor: TG Therapeutics, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06433752)

Clinical Trial Evaluating an Amnion Membrane Allograft Intended for Use in the Management of Non- Healing Venous Leg Ulcers Versus Standard Of Care Alone

Venous Leg Ulcers N/A Interventional 100 participants sought

Professional Education and Research Institute — Roanoke, Virginia (1.1 mi) · Sponsor: Skye Biologics Holdings, LLC

See eligibility & contact on ClinicalTrials.gov (NCT06764953)

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

Kidney Disease, Chronic Phase 3 Interventional 11,000 participants sought

Salem VA Medical Center — Salem, Virginia (5.4 mi) · Sponsor: Boehringer Ingelheim

See eligibility & contact on ClinicalTrials.gov (NCT06531824)

Actively enrolling

Studies you may be able to join near Roanoke

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Google-rated

Top-rated research centers in Roanoke

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Fralin Biomedical Research Institute at VTC

★ 4.4

4 Riverside Circle, Roanoke, VA 24016

(540) 526-2500

Website

"Seen promptly and answered questions"

— Julie White, 4★

Carilion Clinic Center for Simulation, Research and Patient Safety

★ 4.9

15 Old Woods Ave, Roanoke, VA 24016

(540) 855-6860

Website

"Attended a pre-joint replacement class here and it was a great experience well worth mine and my wife's time. Excellent presentations, caring and kno…"

— Bill Jennings, 5★

Salem Research Institute Inc

1970 Roanoke Blvd, Salem, VA 24153

(540) 224-1914

Website

Addiction Recovery Research Center

2 Riverside Circle, Roanoke, VA 24016

(540) 315-0205

Website

Clinical trials in Roanoke: what's recruiting

The Roanoke area currently has 197 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Roanoke, the most active research areas are:

Cancer & Oncology12 studies
Diabetes & Metabolism4 studies
Liver & Kidney3 studies
Heart & Vascular2 studies
Immune & Skin2 studies

Every listing shows the study phase, the recruiting site and its distance from Roanoke, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Roanoke

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Roanoke participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Roanoke pay?

Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.

Do I need to be sick to join a clinical trial in Roanoke?

No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.

Are clinical trials in Roanoke safe?

Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.

Is compensation for clinical trials taxable?

In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.

What is the difference between a research center and a hospital study in Roanoke?

Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.

Paid clinical trials near Roanoke

Other metros within reach

Greensboro, NC596 Winston-Salem, NC597 High Point, NC597 Burlington, NC759 Durham, NC1,679 Cary, NC1,679 Raleigh, NC1,671 Concord, NC627

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Roanoke Bladder Issues Due To Spinal Cord Injury in Roanoke All conditions

More of VA

Arlington2,342 Alexandria2,298 Richmond621 Chesapeake410 Virginia Beach409 Norfolk409 Newport News387 Fredericksburg33

New paid studies open every week

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