Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NC/Winston-Salem
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Winston-Salem, NC

Studies commonly pay $75 to $4,500 per completed study

597 clinical trials are currently recruiting participants within 30 miles of Winston-Salem. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

597studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Winston-Salem right now

Top 25 of 597 recruiting studies, sorted by proximity — each links to its official registry page

Collection and Storage of Tissue Samples From Patients Undergoing Surgery For Suspected Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific N/A Observational 20,000 participants sought
Wake Forest University Comprehensive Cancer Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT00900471)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Novant Health Forsyth Medical Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Wake Forest University Health Sciences — Winston-Salem, North Carolina (1.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

BE WELL With Migraine: Brain Education and WELLness With Migraine

Migraine N/A Interventional 286 participants sought
Wake Forest University Health Sciences — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT05987592)

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Chronic Migraine Phase 3 Interventional 420 participants sought
Headache Wellness Center /ID# 270568 — Greensboro, North Carolina (26.3 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06810505)

Clinical Study of a Vaginal Cooling Device for the Treatment of Vulvovaginal Candidiasis (VVC)

Vulvovaginal Candidiasis (VVC), Yeast Vaginitis N/A Interventional 55 participants sought
Lyndhurst Clinical Research — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Coologics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06983041)

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

Atherosclerotic Cardiovascular Disease (ASCVD) Phase 3 Interventional 340 participants sought
Wake Forest University Baptist Medical Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06813911)

Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure

Heart Failure N/A Interventional 1,200 participants sought
Cone Health — Greensboro, North Carolina (26.3 mi) · Sponsor: Analog Device, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05650541)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Winston-Salem, North Carolina (1.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

Acute HIV Infection Phase 2 Interventional 48 participants sought
3203, Greensboro CRS — Greensboro, North Carolina (26.3 mi) · Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
See eligibility & contact on ClinicalTrials.gov (NCT05719441)

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

Cesarean Delivery, General Anesthesia N/A Observational 5,000 participants sought
Atrium Health Wake Forest Baptist Medical Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Yale University
See eligibility & contact on ClinicalTrials.gov (NCT06030063)

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes N/A Observational 200 participants sought
Atrium Health Wake Forest Baptist (Wake Forest Baptist) — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Jaeb Center for Health Research
See eligibility & contact on ClinicalTrials.gov (NCT06837181)

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

Cystic Fibrosis N/A Observational 400 participants sought
Atrium Health Wake Forest Baptist — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Nicole Hamblett
See eligibility & contact on ClinicalTrials.gov (NCT06504589)

A Study of HyQvia in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) in Routine Clinical Care

Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) N/A Observational 30 participants sought
Wake Forest University - School of Medicine - Central — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Takeda
See eligibility & contact on ClinicalTrials.gov (NCT06538064)

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

Migraine Phase 3 Interventional 200 participants sought
Wake Forest University Baptist Medical Center ( WFUBMC ) — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT06616194)

A Study to Compare TAK-881 and HYQVIA in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Phase 3 Interventional 59 participants sought
Atrium Health Wake Forest Baptist — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Takeda
See eligibility & contact on ClinicalTrials.gov (NCT06747351)

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Percutaneous Coronary Intervention, Peripheral Endovascular Intervention Phase 4 Interventional 6,000 participants sought
Novant Health Forsyth Medical Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT06909565)

Evaluation of Flexible Conductive Hearing Aids

Conductive Hearing Loss N/A Interventional 200 participants sought
Wake Forest University Health Sciences — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT07222202)

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

Diabetes Mellitus, Type 2 Phase 2 Interventional 270 participants sought
PharmQuest — Greensboro, North Carolina (26.3 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07415954)

Assoc. of Genomic Polymorphisms With Cancer Cachexia in Subjects With Panc Adenocarcinoma

Pancreas Adenocarcinoma, Cachexia N/A Observational 100 participants sought
Atrium Health Wake Forest Baptist Comprehensive Cancer Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT05376592)
Actively enrolling

Studies you may be able to join near Winston-Salem

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Winston-Salem

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Clinical Trials of America-NC, LLC

★ 5.0
210 Charlois Blvd #110, Winston-Salem, NC 27103
"Very nice and professional atmosphere. The people there will treat you like family."
— God is real, 5★

PMG Research of Winston-Salem

★ 2.4
1901 S Hawthorne Rd #306, Winston-Salem, NC 27103
(336) 768-8062
"Took my info and said I qualified then never contacted me or returned phone calls."
— Regina Smith, 1★

Southeastern Research Center

2932 Lyndhurst Ave Ste 110, Winston-Salem, NC 27103
(336) 659-8414

Center For Clinical Research

★ 3.0 (4 reviews)
145 Kimel Park Dr #330, Winston-Salem, NC 27103
(336) 765-6181
"ABSOLUTELY NO. ABSOLUTELY NOT.<br>You can thank me later."
— K, 1★

Southeast Clinical Oncology Research Consortium

2150 Country Club Rd, Winston-Salem, NC 27104
(336) 448-1417

Maya Angelou Center for Health Equity

★ 5.0
525 Vine St #150, Winston-Salem, NC 27102
(336) 713-7600
"Congratulations to Dr. Byrd on her recent award from Reynolds to educate the next generation in STEM.<br><br>We applaud your leadership!!!"
— Sheere Mills, 5★

Wake Forest Institute for Regenerative Medicine

★ 4.9
391 Technology Way NE, Winston-Salem, NC 27101
(336) 716-2011
"Some great things going on at Wake in WINSTON-SALEM"
— Anthony Salters, 5★

The Skin Surgery Center for Clinical Research

★ 5.0
725 Highland Oaks Dr Ste 106, Winston-Salem, NC 27103
(336) 200-8208

Center of Excellence for Research, Teaching and Learning

475 Vine St, Winston-Salem, NC 27101
(336) 713-2708

Clinical trials in Winston-Salem: what's recruiting

The Winston-Salem area currently has 597 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Winston-Salem, the most active research areas are:

  • Cancer & Oncology8 studies
  • Diabetes & Metabolism4 studies
  • Heart & Vascular4 studies
  • Brain & Mental Health2 studies
  • Immune & Skin1 studies

Every listing shows the study phase, the recruiting site and its distance from Winston-Salem, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Winston-Salem

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Winston-Salem participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Winston-Salem pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Winston-Salem?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Winston-Salem, NC?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Winston-Salem typically complete one or two studies per year.

Paid clinical trials near Winston-Salem

Other metros within reach

High Point, NC597 Greensboro, NC596 Burlington, NC759 Concord, NC627 Charlotte, NC648 Hickory, NC89 Roanoke, VA197 Gastonia, NC651

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Winston-Salem Chronic Kidney Disease (HealthMatch) in Winston-Salem Bladder Issues Due To Spinal Cord Injury in Winston-Salem All conditions

More of NC

Durham1,679 Cary1,679 Raleigh1,671 Burlington759 Gastonia651 Charlotte648 Concord627 High Point597 Greensboro596 Asheville120 Fayetteville119

New paid studies open every week

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