Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NC/Winston-Salem
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Winston-Salem, NC

Studies commonly pay $75 to $4,500 per completed study

590 clinical trials are currently recruiting participants within 30 miles of Winston-Salem. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

590studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Winston-Salem right now

Top 25 of 590 recruiting studies, sorted by proximity — each links to its official registry page

Collection and Storage of Tissue Samples From Patients Undergoing Surgery For Suspected Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific N/A Observational 20,000 participants sought
Wake Forest University Comprehensive Cancer Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT00900471)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Novant Health Forsyth Medical Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Open Versus Arthroscopic Stabilization of Shoulder Instability With Subcritical Bone Loss: The OASIS Trial

Shoulder Dislocation, Glenohumeral Dislocation N/A Observational 450 participants sought
Wake Forest University — Winston-Salem, North Carolina (1.0 mi) · Sponsor: University of Pittsburgh
See eligibility & contact on ClinicalTrials.gov (NCT04809064)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Wake Forest University Health Sciences — Winston-Salem, North Carolina (1.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease

Chronic Kidney Disease Phase 2 Interventional 465 participants sought
Brookview Hills Research Associates, LLC — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT06717698)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
Novant Health Forsyth Medical Center ( Site 0206) — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

Non-Small Cell Lung Cancer (NSCLC) Phase 3 Interventional 750 participants sought
Novant Health Pharmacy Oncology Specialists — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT07361510)

HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease

Huntington's Disease N/A Observational 2,500 participants sought
Wake Forest University — Winston-Salem, North Carolina (1.0 mi) · Sponsor: University College, London
See eligibility & contact on ClinicalTrials.gov (NCT02855476)

BE WELL With Migraine: Brain Education and WELLness With Migraine

Migraine N/A Interventional 286 participants sought
Wake Forest University Health Sciences — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT05987592)

Evaluation of the Pathobiology of CALR-mutated MPN Cells

Myeloproliferative Neoplasm N/A Observational 35 participants sought
Wake Forest Baptist Comprehensive Cancer Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT06480591)

Telehealth Intervention for Improving Distress and Financial Toxicity in the Caregivers

Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm N/A Interventional 50 participants sought
Wake Forest Baptist Comprehensive Cancer Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT06709404)

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Chronic Migraine Phase 3 Interventional 420 participants sought
Headache Wellness Center /ID# 270568 — Greensboro, North Carolina (26.3 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06810505)

Clinical Study of a Vaginal Cooling Device for the Treatment of Vulvovaginal Candidiasis (VVC)

Vulvovaginal Candidiasis (VVC), Yeast Vaginitis N/A Interventional 55 participants sought
Lyndhurst Clinical Research — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Coologics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06983041)

Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

Complex Regional Pain Syndrome Type I Phase 3 Interventional 270 participants sought
Ambros Clinical Trial Site — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Ambros Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07210515)

Comparative Self-collection for Cervical Cancer Screening Pivotal Study

HPV, HPV - Anogenital Human Papilloma Virus Infection N/A Interventional 260 participants sought
Lyndhurst Clinical Research (Unified) — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Mel Mont Medical
See eligibility & contact on ClinicalTrials.gov (NCT07758140)

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 3 Interventional 1,145 participants sought
Research Site — Winston-Salem, North Carolina (1.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06129864)

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

Atherosclerotic Cardiovascular Disease (ASCVD) Phase 3 Interventional 340 participants sought
Wake Forest University Baptist Medical Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06813911)

ONC-LEUK-2406: The Impact of Systematic Financial Navigation in Acute Myeloid Leukemia

Acute Myeloid Leukemia N/A Interventional 120 participants sought
Atrium Health Wake Forest Baptist Comprehensive Cancer Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT06945042)

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

Large B-cell Lymphoma, Lymphoma, B-Cell Phase 3 Interventional 400 participants sought
Atrium Health Wake Forest Baptist Comprehensive Cancer Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Lyell Immunopharma, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07188558)

A Clinical Study to Evaluate the Efficacy and SPF of Two Test Materials According to an Adaptation of the Guidelines of the FDA Sunscreen Drug Products for Over-the-Counter Human Use

Epidermis, Ultraviolet Exposure Phase 4 Interventional 60 participants sought
Eurofins | CRL, Cosmetics LLC — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Good Molecules, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07789639)

Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity

Chronic Pain, Osteoarthritis, Knee Phase 2 Interventional 38 participants sought
Wake Forest Baptist Health — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT04427709)

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma, Grade 3b Follicular Lymphoma Phase 2 Interventional 396 participants sought
Wake Forest University Health Sciences — Winston-Salem, North Carolina (1.0 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05633615)
Actively enrolling

Studies you may be able to join near Winston-Salem

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research studies for chronic kidney disease

This research platform is enrolling Black and African American adults in eligible areas who have been diagnosed with chronic kidney disease. Compensation may be available. The study team confirms eligibility before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Winston-Salem

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Clinical Trials of America-NC, LLC

★ 5.0
210 Charlois Blvd #110, Winston-Salem, NC 27103
"Very nice and professional atmosphere. The people there will treat you like family."
— God is real, 5★

PMG Research of Winston-Salem

★ 2.4
1901 S Hawthorne Rd #306, Winston-Salem, NC 27103
(336) 768-8062
"Took my info and said I qualified then never contacted me or returned phone calls."
— Regina Smith, 1★

Southeastern Research Center

2932 Lyndhurst Ave Ste 110, Winston-Salem, NC 27103
(336) 659-8414

Center For Clinical Research

★ 3.0 (4 reviews)
145 Kimel Park Dr #330, Winston-Salem, NC 27103
(336) 765-6181
"ABSOLUTELY NO. ABSOLUTELY NOT.<br>You can thank me later."
— K, 1★

Southeast Clinical Oncology Research Consortium

2150 Country Club Rd, Winston-Salem, NC 27104
(336) 448-1417

Maya Angelou Center for Health Equity

★ 5.0
525 Vine St #150, Winston-Salem, NC 27102
(336) 713-7600
"Congratulations to Dr. Byrd on her recent award from Reynolds to educate the next generation in STEM.<br><br>We applaud your leadership!!!"
— Sheere Mills, 5★

Wake Forest Institute for Regenerative Medicine

★ 4.9
391 Technology Way NE, Winston-Salem, NC 27101
(336) 716-2011
"Some great things going on at Wake in WINSTON-SALEM"
— Anthony Salters, 5★

The Skin Surgery Center for Clinical Research

★ 5.0
725 Highland Oaks Dr Ste 106, Winston-Salem, NC 27103
(336) 200-8208

Center of Excellence for Research, Teaching and Learning

475 Vine St, Winston-Salem, NC 27101
(336) 713-2708

Clinical trials in Winston-Salem: what's recruiting

The Winston-Salem area currently has 590 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Winston-Salem, the most active research areas are:

  • Cancer & Oncology13 studies
  • Brain & Mental Health2 studies
  • Liver & Kidney1 studies
  • Heart & Vascular1 studies
  • Immune & Skin1 studies

Every listing shows the study phase, the recruiting site and its distance from Winston-Salem, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Winston-Salem

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Winston-Salem participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Winston-Salem pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Winston-Salem?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Winston-Salem, NC?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Winston-Salem typically complete one or two studies per year.

Paid clinical trials near Winston-Salem

Other metros within reach

High Point, NC590 Greensboro, NC589 Burlington, NC758 Concord, NC635 Charlotte, NC656 Hickory, NC91 Roanoke, VA191 Gastonia, NC653

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Winston-Salem Chronic Kidney Disease (HealthMatch) in Winston-Salem Bladder Issues Due To Spinal Cord Injury in Winston-Salem All conditions

More of NC

Durham1,684 Cary1,684 Raleigh1,677 Burlington758 Charlotte656 Gastonia653 Concord635 High Point590 Greensboro589 Fayetteville124 Asheville118

New paid studies open every week

Get an email when a new clinical trial starts recruiting within 30 miles of your ZIP code. No spam — only real studies from the NIH registry.

By subscribing you agree to receive study alert emails. Unsubscribe anytime in one click.

Get free trial alerts